A microcomputer aided control system for visual tracking task of monkey.

abstract：:The effect of epinephrine (EPI) on the activity of 150 periaqueductal gray (PAG) neurons was examined using extracellular recordings in an in vitro slice preparation. Drop application of EPI inhibited 45%, excited 35%, and had no effect on 20% of PAG neurons. Both the excitatory and inhibitory effects of EPI were of l...

journal_title：Brain research bulletin

authors： Jiang M,Chandler SD,Ennis M,Shipley MT,Behbehani MM

更新日期：1992-12-01 00:00:00

abstract：:Extracellular recordings were made from 467 anti-dromically identified neurosecretory neurons and 148 non-neurosecretory neurons in the paraventricular nucleus of the hypothalamus of hemispherectomized cats under pentobarbital anesthesia. Stimulation of the dorsal, median, and pontine raphe nuclei excited 31%, 26%, an...

journal_title：Brain research bulletin

authors： Kawano S,Osaka T,Kannan H,Yamashita H

更新日期：1992-04-01 00:00:00

abstract：:The antidepressant desipramine has been shown to decrease synaptic membrane concentrations of the norepinephrine re-uptake transporter (NET) in vivo and in vitro, on both an acute and a chronic basis. The possible contribution of decreased NET synthesis to the chronic downregulation of the NETs has not been definitive...

journal_title：Brain research bulletin

authors： Zavosh A,Schaefer J,Ferrel A,Figlewicz DP

更新日期：1999-07-01 00:00:00

abstract：:Waxing and waning electrographic responses (augmenting) and primary evoked responses could be induced in restricted regions of hippocampus, thalamus, and skeletal muscle by bipolar, low-frequency (7-10 Hz), low-amplitude (35 mV-4V) stimulation of selected sites within the hippocampus or thalamus of rabbits. Induction ...

journal_title：Brain research bulletin

authors： Palmer MR,Klemm WR

更新日期：1977-03-01 00:00:00

abstract：:In tests of corticosterone production in vitro, aqueous pineal homogenate (APH) modulates the effect of a short-chain ACTH analogue, ACTH 1-17, added to adrenals from different circadian stages. Adrenal and pineal glands from female B6D2F1 mice, standardized on staggered LD 12:12 regimens, were obtained at the same cl...

journal_title：Brain research bulletin

authors： Sánchez de la Peña S,Halberg F,Halberg E,Ungar F,Cornelissen G,Sánchez E,Brown G,Scheving LE,Yunis EG,Vecsei P

更新日期：1983-07-01 00:00:00

abstract：:Mice selected for differences in nest-building behavior differ in the number of arginine-vasopressin (AVP)-immunoreactive neurons in the suprachiasmatic nuclei (SCN). Although previous efforts to link AVP-immunoreactive neurons in the SCN to clock function have failed, we show that differences in several circadian par...

journal_title：Brain research bulletin

authors： Bult A,Hiestand L,Van der Zee EA,Lynch CB

更新日期：1993-01-01 00:00:00

abstract：:Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter in the mature brain. At an early developmental period, it acts in an excitatory manner that influences many processes of proliferation, migration, and differentiation of the neurons. Previous evidence indicated that manipulation of the GABAergi...

journal_title：Brain research bulletin

authors： Naderipoor P,Amani M,Abedi A,Sakhaie N,Sadegzadeh F,Saadati H

更新日期：2021-01-10 00:00:00

abstract：:Saturation and competition binding studies showed that the turtle brain contains sigma sites labeled by both [3H]di-o-tolylguanidine (DTG) and [3H](+)-pentazocine. There was a significant correlation between the IC50 values of sigma ligands for [3H]DTG sites in the turtle vs. rat brain, suggesting that the sites are c...

journal_title：Brain research bulletin

authors： Matsumoto RR,Bowen WD,de Costa BR,Houk JC

更新日期：1999-03-15 00:00:00

abstract：:Methylphenidate (MPD) is a psychostimulant that enhances dopaminergic neurotransmission in the central nervous system by using mechanisms similar to cocaine and amphetamine. The mode of action of brain circuitry responsible for an animal's neuronal response to MPD is not fully understood. The nucleus accumbens (NAc) h...

journal_title：Brain research bulletin

authors： Chong SL,Claussen CM,Dafny N

更新日期：2012-03-10 00:00:00

abstract：:Neuropathic pain (NP) is a challenge due to our limited understanding of the mechanisms that initiate and maintain chronic pain. The prelimbic division (PrL) of the medial prefrontal cortex (mPFC) is an important area of the emotional and cognitive components of pain and pharmacological systems can interact into the n...

journal_title：Brain research bulletin

authors： Medeiros P,Oliveira-Silva M,Negrini-Ferrari SE,Medeiros AC,Elias-Filho DH,Coimbra NC,de Freitas RL

更新日期：2020-12-01 00:00:00

abstract：:Studies have indicated that glutamate receptor subunit 3 peptide B antibodies (GluR3B Ab's) by directing against a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid subtype glutamate receptors (AMPARs) subunit 3 (GluR3B) was involved in the hippocampal neuron damage in the pathogenesis of epilepsy. Glutamate accumula...

journal_title：Brain research bulletin

authors： Liu Y,Chen Y,Du WT,Wu XX,Dong FX,Qu XB,Fan HB,Yao RQ

更新日期：2017-04-01 00:00:00

abstract：:We studied the ontogeny of muscarinic depression in the developing rat visual cortex using carbachol (a nonhydrolyzable cholinergic agonist) application to neocortical slices obtained from four postnatal age groups: 9-10 days, 15 days, 30-40 days and 18 months. Carbachol suppressed the evoked synaptic response of laye...

journal_title：Brain research bulletin

authors： Vaknin G,Teyler TJ

更新日期：1991-02-01 00:00:00

abstract：:Rats with chronic hippocampal electrode implants had afterdischarges induced with electrical stimulus intensities of 115, 200, and 800% of a previously determined threshold. Afterdischarge duration, postictal EEG depression duration, and the duration of postictal electrical hypoexcitability were assessed. After discha...

journal_title：Brain research bulletin

authors： Swartzwelder HS,Wegener ST,Johnson CT,Dyer RS

更新日期：1980-09-01 00:00:00

abstract：:Fipronil, a GABA(A) receptor antagonist, is replacing many insecticide uses formerly fulfilled by organophosphates like chlorpyrifos. Few studies have addressed the potential for fipronil to produce developmental neurotoxicity. We compared the neurotoxicity of fipronil and chlorpyrifos in undifferentiated and differen...

journal_title：Brain research bulletin

authors： Lassiter TL,MacKillop EA,Ryde IT,Seidler FJ,Slotkin TA

更新日期：2009-03-30 00:00:00

abstract：:Here we asked if insulin activation of the nucleus accumbens in vitro is reflected by an increase in (3)H-deoxyglucose ([(3)H]DG) uptake, thus subserving a new model to study molecular mechanisms of central insulin actions. Additionally, we investigated the dependence of this insulin effect on endocannabinoids and cor...

journal_title：Brain research bulletin

authors： Pinheiro BS,Lemos C,Neutzling Kaufmann F,Marques JM,da Silva-Santos CS,Carvalho E,Mackie K,Rodrigues RJ,Cunha RA,Köfalvi A

更新日期：2016-06-01 00:00:00

abstract：:Microtubules are essential for the development and maintenance of axons and dendrites throughout the life of the neuron, and are vulnerable to degradation and disorganization in a variety of neurodegenerative diseases. Microtubules, polymers of tubulin heterodimers, are intrinsically polar structures with a plus end f...

journal_title：Brain research bulletin

authors： Matamoros AJ,Baas PW

更新日期：2016-09-01 00:00:00

abstract：:The effects of administration of isoproterenol, a beta-adrenergic agonist, and angiotensin II, a peptide, separately and in combination, on water intake and blood pressure of rats were studied. The results of 6 factorially designed studies in which 4 different doses of each compound were administered revealed that wat...

journal_title：Brain research bulletin

authors： Fregly MJ,Threatte RM,Barney CC,Katovich MJ

更新日期：1983-03-01 00:00:00

abstract：:Simple tandem repeats represent more than 1% of the human genome: occasionally they exhibit intergenerational expansibility and are associated with neuromuscular diseases. In transgenic mice the same sequences elicit similar symptoms, but do not expand. We have searched for di-, tri-, and tetra-repeats in the publishe...

journal_title：Brain research bulletin

authors： Astolfi P,Bellizzi D,Losso MA,Sgaramella V

更新日期：2001-10-01 00:00:00

abstract：:Prenatal cocaine exposure increases mu-opioid receptor binding in dopaminergic terminal areas and enhances behavioral responsiveness to mu-opioid agonists. We investigated the influence of early postnatal cocaine treatment on in vitro mu- and delta-opioid receptor activation in male and female weanling rats. Pups rece...

journal_title：Brain research bulletin

authors： Meyer JS,Shani I,Rice D

更新日期：2000-09-15 00:00:00

abstract：:In alpha-chloralose-anesthetized Sprague-Dawley (SD) rats with unilateral nucleus tractus solitarius (NTS) lesions, injection of the alpha(1)-adrenergic receptor agonist phenylephrine into the contralateral NTS dose-dependently increased arterial pressure (AP). Bunazosin (0.1 nmol) or prazosin (0.36 nmol), an alpha(1)...

journal_title：Brain research bulletin

authors： Tsukamoto K,Ito S,Katsunuma N,Hiratsuka M,Masubuchi Y,Kanai T,Kawabe T,Yajima Y,Kanmatsuse K

更新日期：2002-08-15 00:00:00

abstract：:The effect of progesterone (P) on monoamine levels and turnover was evaluated in 8 brain nuclei in estrogen-primed rats. Animals were subcutaneously (SC) injected with P or vehicle 21 hours after SC treatment with 5 micrograms of estradiol benzoate (EB). EB-primed animals treated with P showed high levels of lordosis ...

journal_title：Brain research bulletin

authors： Renner KJ,Krey LC,Luine VN

更新日期：1987-08-01 00:00:00

abstract：:Although increasing evidence indicates that psychiatric symptoms are crucial characteristic of the early stage of Parkinson's disease (PD) and precede motor impairments, the neuronal firing activity of the basolateral nucleus of the amygdala (BLA) in the psychiatric symptom of PD and the involved mechanism are still u...

journal_title：Brain research bulletin

authors： Chen L,Liu J,Zhang QJ,Feng JJ,Gui ZH,Ali U,Wang Y,Fan LL,Hou C,Wang T

更新日期：2011-07-15 00:00:00

abstract：:Impairment of endosomal/lysosomal functions are reported as some of the earliest changes in several age-related neurological disorders such as Alzheimer's disease. Dysregulation of the lysosomal system is also accompanied by the accumulation of age-associated pigments and several recent reports have indicated that thi...

journal_title：Brain research bulletin

authors： Ditaranto-Desimone K,Saito M,Tekirian TL,Saito M,Berg M,Dubowchik G,Soreghan B,Thomas S,Marks N,Yang AJ

更新日期：2003-02-15 00:00:00

abstract：:We celebrate in 1998 the centenary of the discovery of the Golgi apparatus. Neurones have played a special role in the history of this cell organelle, primarily because the endocellular apparatus was discovered in nerve cells by Camillo Golgi when he was studying the cerebellum of an owl. In the following years, the a...

journal_title：Brain research bulletin

authors： Dröscher A

更新日期：1998-10-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in people over 60 years of age in the US and many other developed countries. Increasingly sophisticated methods for the diagnosis and treatment of macular degeneration are not effective for the majority of patients in whom late stage...

journal_title：Brain research bulletin

authors： Rowe-Rendleman C,Glickman RD

更新日期：2004-02-15 00:00:00

abstract：:Chronic cerebral hypofusion (CCH) after bilateral carotid artery occlusion (2VO) causes cognitive damage and neuronal degeneration in the cortex and hippocampal CA1 area, and influences the oxygen and glucose supply in the brain which often results in metabolic alterations and oxidative stress. AMP-activated protein k...

journal_title：Brain research bulletin

authors： Chen Y,Guo Z,Peng X,Xie W,Chen L,Tan Z

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:The effects of COX-2 inhibitors on seizure activity are controversial. The aim of the current study was to determine the post-treatment effect of aceclofenac on penicillin-induced experimental epilepsy. METHODS:Male Wistar rats were used in all experiments (n=18). The seizure activity was triggered by penicill...

journal_title：Brain research bulletin

authors： Taşkıran M,Taşdemir A,Ayyıldız N

更新日期：2017-04-01 00:00:00

abstract：:Concomitant behavioral and dorsal raphe (DR) neuronal activity were recorded following acute and chronic dose response of methylphenidate (MPD) in freely moving rats previously implanted with permanent semi-microelectrodes using telemetric (wireless) technology. On experimental day (ED) 1, the neuronal and locomotor a...

journal_title：Brain research bulletin

authors： Tang B,Dafny N

更新日期：2013-09-01 00:00:00

abstract：:It is well known that some epileptic patients does not respond to conventional treatments, despite multiple combination of antiepileptic drugs, and they are therefore considered drug-resistant. For these patients, vagal nerve stimulation (VNS) represents a successful alternative to traditional therapy, and it is gener...

journal_title：Brain research bulletin

authors： Borghetti D,Pizzanelli C,Maritato P,Fabbrini M,Jensen S,Iudice A,Murri L,Sartucci F

更新日期：2007-06-15 00:00:00

abstract：:Progesterone receptor (PR) isoforms expression was determined in several regions of the prepuberal and adult male rat brain by using reverse transcription coupled to polymerase chain reaction. Rats under a 14:10-h light-dark cycle, with lights on at 0600 h were used. We found that in the hypothalamus of prepuberal ani...

journal_title：Brain research bulletin

authors： Guerra-Araiza C,Reyna-Neyra A,Salazar AM,Cerbón MA,Morimoto S,Camacho-Arroyo I

更新日期：2001-01-01 00:00:00