A fruit firmness QTL identified on linkage group 4 in sweet cherry (Prunus avium L.) is associated with domesticated and bred germplasm.

Abstract:

:Fruit firmness is an important market driven trait in sweet cherry (Prunus avium L.) where the desirable increase in fruit firmness is associated with landrace and bred cultivars. The aim of this work was to investigate the genetic basis of fruit firmness using plant materials that include wild cherry (syn. mazzard), landrace and bred sweet cherry germplasm. A major QTL for fruit firmness, named qP-FF4.1, that had not previously been reported, was identified in three sweet cherry populations. Thirteen haplotypes (alleles) associated with either soft or firm fruit were identified for qP-FF4.1 in the sweet cherry germplasm, and the "soft" alleles were dominant over the "firm" alleles. The finding that sweet cherry individuals that are homozygous for the "soft" alleles for qP-FF4.1 are exclusively mazzards and that the vast majority of the bred cultivars are homozygous for "firm" alleles suggests that this locus is a signature of selection. Candidate genes related to plant cell wall modification and various plant hormone signaling pathways were identified, with an expansin gene being the most promising candidate. These results advance our understanding of the genetic basis of fruit firmness and will help to enable the use of DNA informed breeding for this trait in sweet cherry breeding programs.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Cai L,Quero-García J,Barreneche T,Dirlewanger E,Saski C,Iezzoni A

doi

10.1038/s41598-019-41484-8

subject

Has Abstract

pub_date

2019-03-21 00:00:00

pages

5008

issue

1

issn

2045-2322

pii

10.1038/s41598-019-41484-8

journal_volume

9

pub_type

杂志文章
  • Author Correction: Evaporative deposition of polystyrene microparticles on PDMS surface.

    abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-018-23132-9

    authors: Yu YS,Wang MC,Huang X

    更新日期:2018-03-19 00:00:00

  • Maintenance of aversive memories shown by fear extinction-impaired phenotypes is associated with increased activity in the amygdaloid-prefrontal circuit.

    abstract::Although aversive memory has been mainly addressed by analysing the changes occurring in average populations, the study of neuronal mechanisms of outliers allows understanding the involvement of individual differences in fear conditioning and extinction. We recently developed an innovative experimental model of indivi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep21205

    authors: Laricchiuta D,Saba L,De Bartolo P,Caioli S,Zona C,Petrosini L

    更新日期:2016-02-15 00:00:00

  • The transition state structure for coupled binding and folding of disordered protein domains.

    abstract::Intrinsically disordered proteins are abundant in the eukaryotic proteome, and they are implicated in a range of different diseases. However, there is a paucity of experimental data on molecular details of the coupled binding and folding of such proteins. Two interacting and relatively well studied disordered protein ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep02076

    authors: Dogan J,Mu X,Engström Å,Jemth P

    更新日期:2013-01-01 00:00:00

  • Possible connections of the opposite trends in Arctic and Antarctic sea-ice cover.

    abstract::Sea ice is an important component of the global climate system and a key indicator of climate change. A decreasing trend in Arctic sea-ice concentration is evident in recent years, whereas Antarctic sea-ice concentration exhibits a generally increasing trend. Various studies have investigated the underlying causes of ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep45804

    authors: Yu L,Zhong S,Winkler JA,Zhou M,Lenschow DH,Li B,Wang X,Yang Q

    更新日期:2017-04-05 00:00:00

  • Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin.

    abstract::PP2A is a master controller of multiple inflammatory signaling pathways. It is a target in asthma; however the molecular mechanisms by which PP2A controls inflammation warrant further investigation. In A549 lung epithelial cells in vitro we show that inhibition of basal PP2A activity by okadaic acid (OA) releases rest...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep10063

    authors: Rahman MM,Rumzhum NN,Morris JC,Clark AR,Verrills NM,Ammit AJ

    更新日期:2015-05-18 00:00:00

  • Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector.

    abstract::Multiple approaches utilizing viral and DNA vectors have shown promise in the development of an effective vaccine against HIV. In this study, an alternative replication-defective flavivirus vector, RepliVax (RV), was evaluated for the delivery of HIV-1 immunogens. Recombinant RV-HIV viruses were engineered to stably e...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-56550-4

    authors: Giel-Moloney M,Esteban M,Oakes BH,Vaine M,Asbach B,Wagner R,Mize GJ,Spies AG,McElrath J,Perreau M,Roger T,Ives A,Calandra T,Weiss D,Perdiguero B,Kibler KV,Jacobs B,Ding S,Tomaras GD,Montefiori DC,Ferrari G,Yates

    更新日期:2019-12-27 00:00:00

  • Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state.

    abstract::Moyamoya disease is an idiopathic human cerebrovascular disorder that is characterized by progressive stenosis and abnormal collateral vessels. We recently identified mysterin/RNF213 as its first susceptibility gene, which encodes a 591-kDa protein containing enzymatically active P-loop ATPase and ubiquitin ligase dom...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep04442

    authors: Morito D,Nishikawa K,Hoseki J,Kitamura A,Kotani Y,Kiso K,Kinjo M,Fujiyoshi Y,Nagata K

    更新日期:2014-03-24 00:00:00

  • Development of a quantitative fluorescence-based ligand-binding assay.

    abstract::A major goal of biology is to develop a quantitative ligand-binding assay that does not involve the use of radioactivity. Existing fluorescence-based assays have a serious drawback due to fluorescence quenching that accompanies the binding of fluorescently-labeled ligands to their receptors. This limitation of existin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep25769

    authors: Breen CJ,Raverdeau M,Voorheis HP

    更新日期:2016-05-10 00:00:00

  • Strain-enhanced Dzyaloshinskii-Moriya interaction at Co/Pt interfaces.

    abstract::The interfacial Dzyaloshinskii-Moriya interaction (DMI) is an essential ingredient for stabilizing chiral spin configurations in spintronic applications. Here, via first-principles calculations, we reveal the influence of lattice strain on DMI in Co/Pt interface. We observed a considerable enhancement for a certain la...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-69360-w

    authors: Deger C

    更新日期:2020-07-23 00:00:00

  • SGTA interacts with the proteasomal ubiquitin receptor Rpn13 via a carboxylate clamp mechanism.

    abstract::The fate of secretory and membrane proteins that mislocalize to the cytosol is decided by a collaboration between cochaperone SGTA (small, glutamine-rich, tetratricopeptide repeat protein alpha) and the BAG6 complex, whose operation relies on multiple transient and subtly discriminated interactions with diverse bindin...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep36622

    authors: Thapaliya A,Nyathi Y,Martínez-Lumbreras S,Krysztofinska EM,Evans NJ,Terry IL,High S,Isaacson RL

    更新日期:2016-11-09 00:00:00

  • Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling.

    abstract::Endocannabinoids are small signaling lipids, with 2-arachidonoylglycerol (2-AG) implicated in modulating axonal growth and synaptic plasticity. The concept of short-range extracellular signaling by endocannabinoids is supported by the lack of trans-synaptic 2-AG signaling in mice lacking sn-1-diacylglycerol lipases (D...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep02093

    authors: Keimpema E,Alpár A,Howell F,Malenczyk K,Hobbs C,Hurd YL,Watanabe M,Sakimura K,Kano M,Doherty P,Harkany T

    更新日期:2013-01-01 00:00:00

  • Quantum valley Hall effect in wide-gap semiconductor SiC monolayer.

    abstract::We have investigated the valley Chern number and gapless edge states in wide-gap semiconductor SiC and BN monolayers by using the density functional theory calculations. We found that while SiC monolayer has a non-quantized valley Chern number due to a partial mixing of the Berry curvature peaks pertaining to the oppo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-61906-2

    authors: Lee KW,Lee CE

    更新日期:2020-03-19 00:00:00

  • Steady streaming as a method for drug delivery to the inner ear.

    abstract::The inner ear, or cochlea, is a fluid-filled organ housing the mechanosensitive hair cells. Sound stimulation is relayed to the hair cells through waves that propagate on the elastic basilar membrane. Sensorineural hearing loss occurs from damage to the hair cells and cannot currently be cured. Although drugs have bee...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-79946-z

    authors: Sumner L,Mestel J,Reichenbach T

    更新日期:2021-01-08 00:00:00

  • Quantum phases in circuit QED with a superconducting qubit array.

    abstract::Circuit QED on a chip has become a powerful platform for simulating complex many-body physics. In this report, we realize a Dicke-Ising model with an antiferromagnetic nearest-neighbor spin-spin interaction in circuit QED with a superconducting qubit array. We show that this system exhibits a competition between the c...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep04083

    authors: Zhang Y,Yu L,Liang JQ,Chen G,Jia S,Nori F

    更新日期:2014-02-13 00:00:00

  • On Wiener polarity index of bicyclic networks.

    abstract::Complex networks are ubiquitous in biological, physical and social sciences. Network robustness research aims at finding a measure to quantify network robustness. A number of Wiener type indices have recently been incorporated as distance-based descriptors of complex networks. Wiener type indices are known to depend b...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep19066

    authors: Ma J,Shi Y,Wang Z,Yue J

    更新日期:2016-01-11 00:00:00

  • Phenome-wide association study for CYP2A6 alleles: rs113288603 is associated with hearing loss symptoms in elderly smokers.

    abstract::To identify novel phenotypic associations related to Cytochrome P450 Family 2 Subfamily A Member 6 (CYP2A6), we investigated the human phenome in a total of 11,271 individuals. Initially, we conducted a phenome-wide association study in 3,401 nicotine-exposed elderly subjects considering 358 phenotypic traits. We iden...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-01098-4

    authors: Polimanti R,Jensen KP,Gelernter J

    更新日期:2017-04-21 00:00:00

  • Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice.

    abstract::Photoreceptor degeneration due to retinitis pigmentosa (RP) is a primary cause of inherited retinal blindness. Photoreceptor cell-replacement may hold the potential for repair in a completely degenerate retina by reinstating light sensitive cells to form connections that relay information to downstream retinal layers....

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep29784

    authors: Barnea-Cramer AO,Wang W,Lu SJ,Singh MS,Luo C,Huo H,McClements ME,Barnard AR,MacLaren RE,Lanza R

    更新日期:2016-07-13 00:00:00

  • Shortened leukocyte telomere length is associated with reduced pulmonary function and greater subsequent decline in function in a sample of World Trade Center responders.

    abstract::The objective of this study was to examine whether shorter leukocyte telomere length (LTL) is associated with more rapid pulmonary function decline in a longitudinal study of World Trade Center (WTC) responders. WTC responders (N = 284) participating in a monitoring study underwent blood sampling and were followed pro...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44625-1

    authors: Clouston SAP,Edelman NH,Aviv A,Stewart C,Luft BJ

    更新日期:2019-05-31 00:00:00

  • Global Trends and Regional Variations in Studies of HIV/AIDS.

    abstract::We conduct textual analysis of a sample of more than 200,000 papers written on HIV/AIDS during the past three decades. Using the Latent Dirichlet Allocation method, we disentangle studies that address behavioral and social aspects from other studies and measure the trends of different topics as related to HIV/AIDS. We...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-04527-6

    authors: Baghaei Lakeh A,Ghaffarzadegan N

    更新日期:2017-06-23 00:00:00

  • Understanding solute effect on grain boundary strength based on atomic size and electronic interaction.

    abstract::Solute segregating to grain boundary can stabilize the microstructure of nanocrystalline materials, but a lot of solutes also cause embrittlement effect on interfacial strength. Therefore, uncovering the solute effect on grain boundary strength is very important for nanocrystalline alloys design. In this work, we have...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-74065-1

    authors: Huang Z,Wang P,Chen F,Shen Q,Zhang L

    更新日期:2020-10-08 00:00:00

  • Early change in circulating tumor DNA as a potential predictor of response to chemotherapy in patients with metastatic colorectal cancer.

    abstract::The impact of ctDNA changes after chemotherapy on the clinical outcomes of patients with metastatic colorectal cancer (mCRC) remains unclear. The present study evaluated the clinical implications of the early change in ctDNA levels as a predictor of objective response and clinical outcome in mCRC patients who received...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-53711-3

    authors: Osumi H,Shinozaki E,Yamaguchi K,Zembutsu H

    更新日期:2019-11-22 00:00:00

  • Absorption of α-tocopheryl acetate is limited in mink kits (Mustela vison) during weaning.

    abstract::Bioavailability of α-tocopherol varies with source, dose and duration of supplementation. The effect of source and dose of α-tocopherol on response of α-tocopherol stereoisomers in plasma and tissues of mink kits during the weaning period was studied. Twelve mink kits were euthanised in CO2 at the beginning of the exp...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-80902-0

    authors: Lashkari S,Clausen TN,Foldager L,Jensen SK

    更新日期:2021-01-29 00:00:00

  • Dna is a New Target of Parp3.

    abstract::Most members of the poly(ADP-ribose)polymerase family, PARP family, have a catalytic activity that involves the transfer of ADP-ribose from a beta-NAD+-molecule to protein acceptors. It was recently discovered by Talhaoui et al. that DNA-dependent PARP1 and PARP2 can also modify DNA. Here, we demonstrate that DNA-depe...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-22673-3

    authors: Belousova EA,Ishchenko АA,Lavrik OI

    更新日期:2018-03-08 00:00:00

  • The T cell receptor resides in ordered plasma membrane nanodomains that aggregate upon patching of the receptor.

    abstract::Two related models for T cell signalling initiation suggest either that T cell receptor (TCR) engagement leads to its recruitment to ordered membrane domains, often referred to as lipid rafts, where signalling molecules are enriched or that ordered TCR-containing membrane nanodomains coalesce upon TCR engagement. That...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep10082

    authors: Dinic J,Riehl A,Adler J,Parmryd I

    更新日期:2015-05-08 00:00:00

  • Monkeys share the neurophysiological basis for encoding sound periodicities captured by the frequency-following response with humans.

    abstract::The extraction and encoding of acoustical temporal regularities are fundamental for human cognitive auditory abilities such as speech or beat entrainment. Because the comparison of the neural sensitivity to temporal regularities between human and animals is fundamental to relate non-invasive measures of auditory proce...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-16774-8

    authors: Ayala YA,Lehmann A,Merchant H

    更新日期:2017-11-30 00:00:00

  • Food knowledge depends upon the integrity of both sensory and functional properties: a VBM, TBSS and DTI tractography study.

    abstract::Food constitutes a fuel of life for human beings. It is therefore of chief importance that their recognition system readily identifies the most relevant properties of food by drawing on semantic memory. One of the most relevant properties to be considered is the level of processing impressed by humans on food. We hypo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-43919-8

    authors: Vignando M,Aiello M,Rinaldi A,Cattarruzza T,Mazzon G,Manganotti P,Eleopra R,Rumiati RI

    更新日期:2019-05-15 00:00:00

  • µ-opioid receptor-mediated downregulation of midline thalamic pathways to basal and central amygdala.

    abstract::Brain µ-opioid receptors (MOR) mediate reward and help coping with pain, social rejection, anxiety and depression. The dorsal midline thalamus (dMT) integrates visceral/emotional signals and biases behavior towards aversive or defensive states through projections to the amygdala. While a dense MOR expression in the dM...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54128-8

    authors: Goedecke L,Bengoetxea X,Blaesse P,Pape HC,Jüngling K

    更新日期:2019-11-28 00:00:00

  • The strange flight behaviour of slowly spinning soccer balls.

    abstract::The strange three-dimensional flight behaviour of slowly spinning soccer balls is one of the most interesting and unknown phenomenon associated with the trajectories of sports balls. Many spectators have experienced numerous exciting and emotional instances while observing the curious flight behaviour of these balls. ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep01871

    authors: Mizota T,Kurogi K,Ohya Y,Okajima A,Naruo T,Kawamura Y

    更新日期:2013-01-01 00:00:00

  • Epidermal CD147 expression plays a key role in IL-22-induced psoriatic dermatitis.

    abstract::Psoriasis is a chronic inflammatory skin disease characterized by abnormal keratinocyte proliferation and terminal differentiation. Interleukin-22 (IL-22) and the transcription factor Stat3 play pivotal roles in the pathogenesis of psoriasis. CD147 is a transmembrane glycosylation protein that belongs to the immunoglo...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep44172

    authors: Peng C,Zhang S,Lei L,Zhang X,Jia X,Luo Z,Huang X,Kuang Y,Zeng W,Su J,Chen X

    更新日期:2017-03-08 00:00:00

  • Ecosystem carbon storage in forest fragments of differing patch size.

    abstract::Forest fragmentation threatens the ecosystem carbon (C) storage. The distribution patterns of ecosystem C density are poorly documented for fragmented forests of differing patch size. The objectives of this study were to examine C density in these forest ecosystems and the influence of edge effects on C density. Allom...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-13598-4

    authors: Ma L,Shen C,Lou D,Fu S,Guan D

    更新日期:2017-10-13 00:00:00