Abstract:
:A 54-year-old man with multiple endocrine neoplasia type 1 had previous history of parathyroid surgery and left thyroid lobectomy 5 years earlier, and was referred for recurrent hypoglycemic episodes. Ga-DOTATATE PET/CT had showed multiple lesions in the right lung, liver, and pancreas. Biopsy from pancreas revealed low-grade neuroendocrine neoplasia. After 2 fractions of Lu-DOTATATE therapy, the size of lesions and its activity reduced on the Ga-DOTATATE scan and the hypoglycemic episodes manifested every day have scaled down to 1 time over 1-year follow-up. Herein, we report a case of malignant insulinoma successfully treated with radiolabeled somatostatin receptor therapy using Lu-DOTATATE.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Novruzov F,Mehmetbeyli L,Aliyev JA,Abbasov B,Mehdi Edoi
10.1097/RLU.0000000000002500subject
Has Abstractpub_date
2019-06-01 00:00:00pages
e415-e417issue
6eissn
0363-9762issn
1536-0229journal_volume
44pub_type
杂志文章abstract::Limping is a frequent occurrence in children and may be caused by various conditions, including trauma, inflammation, infection, and malignancy. Nontraumatic avascular necrosis of the tarsal bones should be included in the differential diagnosis. Accumulated data have supported the superiority of bone scans to radiogr...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000255026.52044.85
更新日期:2007-03-01 00:00:00
abstract::Findings on cholescintigraphy in gallbladder carcinoma are described in five patients. Four patients presenting with acute cholecystitis had nonvisualization of the gallbladder with normal hepatoenteric transit time. One of these had a large portal mass and two had liver metastasis as additional findings. The fifth pa...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198604000-00013
更新日期:1986-04-01 00:00:00
abstract::A 48-year-old man experienced recurrent vertigo refractory to antiplatelet medications. Cerebral angiography showed occlusion of bilateral vertebral arteries with poor collateral circulation. PET using O2 gas showed reduced blood flow and metabolic rate of oxygen and elevated oxygen extraction fraction in bilateral ce...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002469
更新日期:2019-04-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001125
更新日期:2016-06-01 00:00:00
abstract::Usefulness of N-isopropyl-p-I-123 iodoamphetamine (I-123 IMP) for the detection of malignant melanoma and malignant lymphoma is well known. The appropriate interval from administration until image acquisition is unusual because the accumulation mechanism is different. We present a case of choroidal melanoma of the rig...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3180a1abbd
更新日期:2007-08-01 00:00:00
abstract::When early complications occur after a kidney transplant, radionuclide angiography may be useful in determining a possible vascular origin. The authors describe the case of a patient with anuria continuing 24 hours after transplantation. Radionuclide angiography showed a defect at the site of the renal graft, suggesti...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199111000-00012
更新日期:1991-11-01 00:00:00
abstract:PURPOSE:Investigate the ability of F-fluorothymidine (FLT) PET combined with CT at 6 weeks to predict treatment response at 12 weeks after treatment with pembrolizumab. METHODS:Five patients with unresectable stage IV melanoma were included in this single-institution pilot study. Patients underwent FLT-PET/CT (baselin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002967
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:This report highlights the presence of extensive cerebral dysfunction in a patient with cerebral mitochondrial disorder. MATERIALS AND METHODS:The patient is a 10-year-old girl with a history of hemiparesis, encephalopathy, developmental delay, and seizures. She underwent 1H magnetic resonance spectroscopic im...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31817dec3c
更新日期:2008-08-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200411000-00004
更新日期:2004-11-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000402
更新日期:2014-07-01 00:00:00
abstract::Primary squamous cell carcinoma of the thyroid is rare. We present FDG PET/CT findings on 2 male patients with primary squamous cell carcinoma of the thyroid. Elevated FDG activity was visualized on primary thyroid tumor and metastatic lesions on both patients. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000511
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the role of ⁶⁸Ga-DOTANOC (⁶⁸Gallium-labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI³-octreotide) PET/CT for localization of the primary tumor in patients with carcinoma of unknown primary of neuroendocrine origin. MATERIAL AND METHODS:Twenty patients (median age, 55 years...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31823ea730
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To investigate the significance of increased perfusion associated with some hepatic hemangiomata during radionuclide blood volume imaging. METHODS:Immediate dynamic planar projections and delayed SPECT imaging of a hepatic lesion were obtained after the administration of Tc-99m-labeled RBC. Scintigraphic data ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199708000-00006
更新日期:1997-08-01 00:00:00
abstract::A 52-year-old man with metastatic poorly differentiated bronchogenic carcinoma and serum calcium levels as high as 14.6 had intense Tc-99m MDP uptake found throughout the stomach wall on SPECT imaging. FDG uptake assessed by PET imaging was not elevated in the stomach, whereas multiple hyper-metabolic tumor foci could...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199509000-00002
更新日期:1995-09-01 00:00:00
abstract:ABSTRACT:A 13-year-old boy with mediastinal T-cell lymphoblastic lymphoma demonstrated an altered biodistribution with diffuse activity in subcutaneous white adipose tissue and decreased visceral activity on interim posttreatment FDG PET/CT. This altered biodistribution was attributed to administration of the chemother...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003340
更新日期:2021-03-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200109000-00001
更新日期:2001-09-01 00:00:00
abstract::O-(2-fluoroethyl)-L-tyrosine (FET) PET/CT is a promising imaging modality for brain tumor imaging because of its reported high sensitivity for biologically active tumor tissue. We present a case of biopsy-proven neurosarcoidosis showing FET uptake. It is an important cause of false-positive uptake on FET PET/CT. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001516
更新日期:2017-03-01 00:00:00
abstract::Melorheostosis is a rare but benign disorder characterized by asymmetric osteosclerotic dysplasia. Radiographic appearances are characteristic and described as "melting wax flowing down a candle." This disorder may involve more than one bone contiguously across the joints following a sclerotomal distribution. It is of...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318208f517
更新日期:2011-03-01 00:00:00
abstract::To determine the potential of Tc-99m MIBI for detecting bone marrow malignancy, MIBI imaging of the femur was evaluated. There was no detectable MIBI activity in 125 of 141 (89%) control patients. Clearly demonstrated focal or tubular MIBI activity indicating intramedullary accumulation was demonstrated in 44 of 45 (9...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199810000-00004
更新日期:1998-10-01 00:00:00
abstract:INTRODUCTION:Patients with radioiodine-refractory differentiated thyroid cancer (RrDTC) have a rather poor prognosis and are in need of novel treatments. As RrDTCs can in some cases express somatostatin receptors (SSRT), targeting of these receptors by Ga/Lu-DOTATATE could evolve as a novel theranostic option. METHODS...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002219
更新日期:2018-10-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31815c513c
更新日期:2008-01-01 00:00:00
abstract::The spongy body of the penis metastasis from other primary sites is a rare clinical entity. It is frequently associated with widespread metastatic disease and poor prognosis clinically. We report a case of a 61-year-old man with a previous history of cystectomy due to infiltrating urothelial carcinoma of the bladder 1...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000974
更新日期:2016-05-01 00:00:00
abstract::Incidental thyroid FDG uptake is not rarely encountered on PET studies. In this case, we present an incidental thyroid focus of F-FDG uptake identified in a patient with splenic marginal zone lymphoma during the baseline and the response assessment PET/CT study that proved to be medullary thyroid carcinoma on subseque...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001290
更新日期:2016-10-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.rlu.0000246818.24566.54
更新日期:2006-12-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000089521.56809.e7
更新日期:2003-10-01 00:00:00
abstract:INTRODUCTION:The purpose of presurgical assessment is to delimit the epileptogenic zone and the functional deficit zone with a brain MRI, an electroencephalograph or even a stereo-electroencephalograph (SEEG), neuropsychological evaluation, and a cerebral FDG PET. Several studies concur that the hypometabolism of FDG P...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002615
更新日期:2019-07-01 00:00:00
abstract::PET/CT with Ga-labeled prostate-specific membrane antigen (PSMA) is increasingly recognized as the best imaging modality for disease staging and detection of recurrent prostate cancer. Despite its name, PSMA expression has been reported in a number of nonprostatic benign and malignant pathologies. Apparently, angioneo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002103
更新日期:2018-07-01 00:00:00
abstract::The usefulness of F-18 2'-deoxy-2-fluoro-D-glucose (FDG) positron emission tomography (PET) has been well established for lymphoma staging. Although involvement of the pancreas occurs in more than one third of patients with non-Hodgkin lymphoma, primary lymphoma of the pancreas accounts for less than 1% of extranodal ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000135269.00531.f8
更新日期:2004-09-01 00:00:00
abstract::Use of F-18 fluorodeoxyglucose positron emission tomography (F-18 FDG PET) in patients with known thyroid cancer is well documented, but the role of this imaging modality in the initial workup of a thyroid nodule has not been defined. The incidental finding of a hypermetabolic focus in the thyroid on F-18 FDG PET in p...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
doi:10.1097/01.rlu.0000082675.64816.22
更新日期:2003-09-01 00:00:00
abstract::Sodium fluoride (NaF) is a bone-seeking positron-emitting tracer with high sensitivity and specificity for detection of osseous lesions, particularly osteolytic lesions. We believe that NaF positron emission tomography (PET)/computed tomography (CT) scans can provide a more thorough and conclusive evaluation of bone d...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31824c81ee
更新日期:2012-05-01 00:00:00