Abstract:
INTRODUCTION:The purpose of presurgical assessment is to delimit the epileptogenic zone and the functional deficit zone with a brain MRI, an electroencephalograph or even a stereo-electroencephalograph (SEEG), neuropsychological evaluation, and a cerebral FDG PET. Several studies concur that the hypometabolism of FDG PET seems to be consistent with epileptogenic zones. We compared the functional deficit zone defined by FDG PET with the results of the SEEG, for each cluster electrode contact (CEC) located in the gray matter. METHODS:The electrode diagram of the 15 patients (486 CECs) operated on for drug-resistant epilepsy was merged with MRI and FDG PET. The metabolisms of FDG PET and SEEG were compared using a logistic regression test. RESULTS:The presence of hypometabolism resulted in a significantly higher risk of being in the seizure onset zone and the irritative zone, particularly when it was intense. Of the deeply hypometabolic CECs, 47% were in the seizure onset zone and 76% in the irritative zone. Normal metabolism resulted in a significantly higher probability of being in the healthy zone. CONCLUSIONS:This study demonstrated an association between the presence of normal metabolism and the location of CECs in the healthy zone, and between the presence of pathological metabolism and the location of CECs in the seizure onset zone and the irritative zone, with metabolism abnormalities progressively more present and more intense near the seizure onset zone.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Montaz-Rosset MS,Scholly J,Voulleminot P,Severac F,Hirsch E,Valenti-Hirsch MP,Namer IJdoi
10.1097/RLU.0000000000002615subject
Has Abstractpub_date
2019-07-01 00:00:00pages
526-531issue
7eissn
0363-9762issn
1536-0229journal_volume
44pub_type
杂志文章abstract::We report two cases of supra-scrotal vasitis incidentally detected in patients who had undergone mesh herniorrhaphy. PET/CT in patients undergoing lymphoma work-up and health check-up revealed hypermetabolic dilatation of vas deferens in the external iliac area. There were no symptoms, and blood test results did not i...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002402
更新日期:2019-02-01 00:00:00
abstract::During a Tc-99m DTPA study, activity simultaneously appeared in the kidneys and in a right lateral band. This was due to an inflammatory tract and not to urinary drainage. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198601000-00020
更新日期:1986-01-01 00:00:00
abstract::Gallium-67 citrate imaging for the staging of lymphomas was performed in three patients receiving Corynebacterium parvum (C. parvum) immunotherapy. Unexpected uptake at the site of C. parvum injections was identified and although the mechanism of localization is not determined by this study, similarities between C. pa...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197809000-00009
更新日期:1978-09-01 00:00:00
abstract::The authors evaluated the clinical applications of Tc-99m methoxy isobutyl isonitrile (MIBI) in the simultaneous assessment of ventricular function and myocardial perfusion in patients with congenital heart disease. Global ventricular function was assessed by first-pass ECG gated study. Myocardial perfusion was evalua...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199401000-00009
更新日期:1994-01-01 00:00:00
abstract::Urachal inflammation is rarely seen in adults. Two patients with suspected abdominal tumor underwent FDG PET/CT. One patient showed an irregular hypermetabolic mass anterosuperior to the bladder. The other patient showed a thick-walled cystic mass with strong FDG uptake extending from the bladder dome to the anterior ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31827a263e
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:FDG PET-CT plays a critical role in the management of head and neck cancer patients. After therapy, many patterns of altered physiologic FDG uptake have been recognized. In our institution, we noticed patterns of head and neck muscle uptake that were unique in the post-therapy scans of head and neck cancer p...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181e05d94
更新日期:2010-07-01 00:00:00
abstract::The amino-terminal domain of fibronectin has a fibrin binding site and a site for covalent cross-linking to fibrin. This fibrin binding domain was isolated from human recombinant fibronectin and labeled with In-111; the final molecular weight was 12 kD. It was applied to a pilot study of 62 patients; 30 who were thoug...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/00003072-199505000-00004
更新日期:1995-05-01 00:00:00
abstract::Studies have suggested that Tc-99m white blood cell (WBC) imaging is superior to contrast radiology for assessing the extent and activity of inflammatory bowel disease (IBD). The Tc-99m WBC scan seems ideally suited to obtain, in only one examination, a precise temporal snapshot of the distribution and intensity of in...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
doi:10.1097/00003072-200009000-00012
更新日期:2000-09-01 00:00:00
abstract::The liver was not visualized by In-111 WBC scan in a patient with alcoholic liver disease. The liver was visualized on repeat scan when liver function had improved. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198602000-00002
更新日期:1986-02-01 00:00:00
abstract::A 74-year-old man presented to our hospital for a 2-month history of worsening feet and left hand swelling pain. Computed tomography reconstruction image and sagittal images of the left foot demonstrated multiple and irregular bone destruction. Orthopedic surgeon suspected tuberculosis or primary skeletal malignancy. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000755
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the feasibility of using Ga PSMA-11 PET/CT for imaging brain lesions and its comparison with F-FDG. METHODS:Ten patients with brain lesions were included in the study. Five patients were treated cases of glioblastoma with suspected recurrence. F-FDG and Ga PSMA-11 brain scans were done for these ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001451
更新日期:2017-01-01 00:00:00
abstract::Technetium-99m labeled human serum albumin has been shown to detect protein leakage into the bowel. A case of a young adult is presented with endoscopic and pathological correlation of scintigraphic findings supporting Menètrier's disease. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199502000-00004
更新日期:1995-02-01 00:00:00
abstract:PURPOSE:To determine whether rapid, dynamic SPECT imaging with Tc-99m labeled red blood cells was technically feasible and of value in the detection of cavernous hemangiomas of the liver. MATERIALS AND METHODS:The acquisition protocol for Tc-99m labeled red blood cell imaging of hepatic hemangiomas was modified with s...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199711000-00001
更新日期:1997-11-01 00:00:00
abstract::Tc-99m sulfur colloid has been shown to be accurate in the detection of intrapulmonary bleeding (1,2). The present example demonstrates the usefulness of Tc-99m sulfur colloid in identifying an unusual manifestation of intrathoracic hemorrhage. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198411000-00020
更新日期:1984-11-01 00:00:00
abstract::C-acetate uptake could be increased in physiologic or inflammatory conditions without evidence of cancer. We report a hepatocellular carcinoma patient with sorafenib-induced metabolic acidosis, who showed increased hepatic uptake of C-acetate. C-acetate PET/CT might be a potentially useful surrogate marker to monitor ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001879
更新日期:2018-01-01 00:00:00
abstract::The authors have previously shown that the definition of ablation of thyroid tissue in patients treated with thyroidectomy and radioiodine (I-131) for thyroid carcinoma depends upon the dose of I-131 used to scan the patient. The therapeutic response to I-131 therapy was evaluated in a group of ten differentiated thyr...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198510000-00003
更新日期:1985-10-01 00:00:00
abstract::Two radiocolloid preparations, differing in particle size by a factor of 5 to 20, were compared in each of 15 patients. The smaller colloid, measuring less than 80 nm, showed a relative decrease in the calculated target to background ratios for the liver and spleen and an increase for the bone marrow. The increased up...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198105000-00005
更新日期:1981-05-01 00:00:00
abstract:PURPOSE:To evaluate the findings and usefulness of Ga-67 scanning in recent cases of tuberculosis (TB). MATERIALS AND METHODS:The authors reviewed chest x-ray films and Ga-67 citrate scans of 52 patients with culture-confirmed infection caused by Mycobacterium tuberculosis treated after 1988. RESULTS:Ga-67 scans were...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199707000-00005
更新日期:1997-07-01 00:00:00
abstract::Hairy cell leukemia is a rare hematologic malignancy characterized by splenomegaly, pancytopenia, and susceptibility to infections. We report a case of a 66-year-old man, diagnosed with hairy cell leukemia, without severe cytopenias and splenomegaly, but with an extensive pathological retroperitoneal mass and infiltra...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002557
更新日期:2019-07-01 00:00:00
abstract:PURPOSE OF THE REPORT:Extrahepatic bile duct (EHD) cancer varies in uptake of FDG. The aim of the present study was to determine the role of glucose transporter (GLUT) 1 and hexokinase (HK) 2 in the glucose metabolism of EHD cancer cells using immunohistochemistry and 18F-FDG PET/CT. METHODS:Twenty-six patients with E...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000640
更新日期:2015-03-01 00:00:00
abstract::Tc-99m pertechnetate radionuclide scrotal scanning was performed on nine hospitalized boys with anaphylactoid purpura and acute scrotal tenderness. Scrotal involvement in anaphylactoid purpura is generally a part of the basic pathological process (i.e., vasculitis). Sometimes testicular torsion could not be excluded b...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199304000-00006
更新日期:1993-04-01 00:00:00
abstract::A 51-year-old man presented with cough and pain in his upper chest for 1 week. Chest CT showed an ill-defined right paratracheal mass with slight enhancement in the upper mediastinum. A FDG PET/CT was performed showing focal increased FDG uptake with SUVmax of 4.7 in the mass. The mass was excised surgically. Histopat...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002860
更新日期:2020-02-01 00:00:00
abstract::A 26-year-old man had unilateral facial numbness. A brain MRI suggested possible brain metastases. F-FDG and C-choline PET/CT revealed multiple sites of abnormal activity in the body. However, C-choline PET/CT was more impressive than FDG PET/CT. Especially, the brain lesions revealed by MRI had only elevated C-cholin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001324
更新日期:2016-10-01 00:00:00
abstract::Measurement of relative renal function in azotemic patients can be misleading due to elevated background activity and delayed renal concentration of radiotracer. When there is delayed excretion of the tracer and obvious splenic or hepatic activity superimposed over one of the kidneys, it often is advantageous to delay...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199305000-00002
更新日期:1993-05-01 00:00:00
abstract::The neuroendocrine small cell carcinoma of the cervix is a rare malignancy that has a poor prognosis due to early lymphatic and hematogenous spread. We herein report a case of a 27- year-old woman who was referred for initial staging of a neuroendocrine small cell carcinoma with previous unremarkable structural imagin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001498
更新日期:2017-03-01 00:00:00
abstract::Lower neck uptake in bone scan is hard to interpret because of superposition of several structures. Single photon emission computerized tomography can be beneficial, as illustrated in this patient with a laryngeal tumor. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198312000-00012
更新日期:1983-12-01 00:00:00
abstract::Central neurocytoma is a rare benign tumor of neuronal origin. The tumor is often located in the ventricular system and can proliferate within the ventricle. Five months after stereotactic radiosurgery for recurrent neurocytoma, a 33-year-old woman had a 2.0-cm lesion in the right third ventricle on the MRI. FDG PET d...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318286bdea
更新日期:2013-06-01 00:00:00
abstract::Computed tomography is the standard diagnostic examination employed to identify the morbid anatomy of cerebrospinal fluid spaces in children. This noninvasive technique provides excellent anatomic information. However, CT only indirectly characterizes the cerebral spinal fluid pathways. When it is necessary to determi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197910000-00006
更新日期:1979-10-01 00:00:00
abstract::The cerebral hemodynamics and oxygen metabolism before and after the recanalization of the occluded sinus were evaluated using O-15 positron emission tomography (PET) scanning in a 21-year-old woman with superior sagittal sinus thrombosis. During the initial presentation, there was increased regional cerebral blood vo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000162603.26986.ac
更新日期:2005-06-01 00:00:00
abstract::Brain death is the complete, irreversible cessation of brain function, including the capacity for brainstem, respiratory, and vegetative activities. It is a clinical diagnosis that can be supplemented with brain perfusion imaging. Absent cerebral blood flow can be visualized with CT angiography or perfusion scintigrap...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003237
更新日期:2020-10-01 00:00:00