68Ga-Labeled PSMA Uptake in Nonprostatic Malignancies: Has the Time Come to Remove "PS" From PSMA?

Abstract:

:PET/CT with Ga-labeled prostate-specific membrane antigen (PSMA) is increasingly recognized as the best imaging modality for disease staging and detection of recurrent prostate cancer. Despite its name, PSMA expression has been reported in a number of nonprostatic benign and malignant pathologies. Apparently, angioneogenesis is the mechanism attributed to increased Ga-PSMA uptake at these sites. Here we illustrate the utility of Ga-PSMA in 5 nonprostatic malignancies that could open up new possibilities for diagnostics and theranostic concepts with PSMA labeled radioligands in nonprostate tumor entities.

journal_name

Clin Nucl Med

authors

Malik D,Kumar R,Mittal BR,Singh H,Bhattacharya A,Singh SK

doi

10.1097/RLU.0000000000002103

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

529-532

issue

7

eissn

0363-9762

issn

1536-0229

journal_volume

43

pub_type

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