Complementary nature of radiotracer parathyroid imaging and intraoperative parathyroid hormone assays in the surgical management of primary hyperparathyroid disease: case report and review.

Abstract:

PURPOSE:This article illustrates the complementary nature of preoperative radionuclide parathyroid imaging and intraoperative rapid parathyroid hormone (PTH) assays in primary hyperparathyroid disease. The authors review the literature on these procedures and compare this protocol and its cost-effectiveness with those of the classic four-gland exploration. MATERIALS AND METHODS:Preoperative parathyroid imaging with Tc-99m MIBI and intraoperative rapid PTH assays were performed at the time of neck exploration. RESULTS:One of two parathyroid adenomas seen on radionuclide images would have been missed if the authors had relied solely on the initial decrease in PTH assay value to a normal level. CONCLUSIONS:Tc-99m MIBI imaging and intraoperative rapid PTH assays are complementary; when used together, they lessen the likelihood that abnormal parathyroid glands will be overlooked. This experience and that of others suggest these combined procedures are cost-effective.

journal_name

Clin Nucl Med

authors

Wilkinson RH Jr,Leight GS Jr,Garner SC,Borges-Neto S

doi

10.1097/00003072-200003000-00002

keywords:

subject

Has Abstract

pub_date

2000-03-01 00:00:00

pages

173-8

issue

3

eissn

0363-9762

issn

1536-0229

journal_volume

25

pub_type

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