Atherogenic cytokines and chemokines in chronic hepatitis C are not associated with the presence of cardiovascular diseases.

abstract：:Peptic ulcer is a lesion in the mucosa of the digestive tract affecting many people all around the world. Recent investigations have indicated that produced inflammatory cytokines such as TNF-α and IL-1β in response to gastric infection by Helicobacter pylori play an important role in the development of peptic ulcer. ...

journal_title：Cytokine

authors： Tourani M,Habibzadeh M,Karkhah A,Shokri-Shirvani J,Barari L,Nouri HR

更新日期：2018-10-01 00:00:00

abstract：:CoPoIFN-α is a recombinant non-naturally occurring porcine interferon-α (IFN-α). It was designed by scanning 17 porcine IFN-α nonallelic subtypes and assigning the most frequently occurring amino acid in each position. We used a porcine IFN-α (PoIFN-α) derived from domestic pig as a control. Both porcine IFN-α genes w...

journal_title：Cytokine

authors： Huang L,Cao RB,Wang N,Liu K,Wei JC,Isahg H,Song LJ,Zuo WY,Zhou B,Wang WW,Mao X,Chen PY

更新日期：2012-01-01 00:00:00

abstract：:IL-18 is a pleiotropic and multifunctional cytokine that belongs to the IL-1 family. It is produced as a biologically inactive precursor, which is cleaved into its active mature form mainly by caspase-1. The caspase becomes active from its inactive precursor (procaspase-1) upon assembly of an inflammasome. Because of ...

journal_title：Cytokine

authors： Samarani S,Allam O,Sagala P,Aldabah Z,Jenabian MA,Mehraj V,Tremblay C,Routy JP,Amre D,Ahmad A

更新日期：2016-06-01 00:00:00

abstract：:CC Chemokine ligand 22 (Ccl22) is a selective, high affinity ligand at the CC chemokine receptor 4 (Ccr4). We have identified cDNAs encoding both ligand and receptor of the Ccl22-Ccr4 pair in cDNA libraries of the anterior hypothalamus/pre-optic area (AH/POA) by PCR. The AH/POA is the key brain region where endogenous...

journal_title：Cytokine

authors： Osborn O,Sanchez-Alavez M,Dubins JS,Gonzalez AS,Morrison B,Hadcock JR,Bartfai T

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND/AIMS:Infliximab (Ifx) is effective in the treatment of Crohn's disease (CD) and rheumatoid arthritis (RA), etanercept (Eta) in RA but not in CD. The mechanisms underlying these clinical differences are not fully understood, but this knowledge could be valuable to identify responders and develop new treatment...

journal_title：Cytokine

authors： Agnholt J,Dahlerup JF,Kaltoft K

更新日期：2003-08-07 00:00:00

abstract：OBJECTIVE:To examine the expression of chemokine receptors in different peripheral blood T-cell subsets in patients with polymyositis (PM) and dermatomyositis (DM). METHODS:We used flow cytometry to measure the frequencies of chemokinereceptors CXCR3 and CCR4 expression in the CD4+ or CD8+ lymphocytes. Enzyme linked i...

journal_title：Cytokine

authors： Zhu Z,Yang C,Wang J,Feng Q,Chen Q,Yang P

更新日期：2017-11-01 00:00:00

abstract：:Previous studies have suggested that heterotrimeric G(i) proteins, Src tyrosine kinase and phosphatidylinositol-3 kinase (PI3 Kinase) are involved in signaling events induced by lipopolysaccharide (LPS) leading to pro-inflammatory cytokines gene expression. To investigate the involvement of these mediators in Gram-pos...

journal_title：Cytokine

authors： Fan H,Teti G,Ashton S,Guyton K,Tempel GE,Halushka PV,Cook JA

更新日期：2003-06-07 00:00:00

abstract：:Among New Mexican Hispanic women, breast cancer is detected at a more advanced stage than compared to Non-Hispanic White women. One central factor that has been little studied is the role of critical cytokines. We genotyped incident breast cancer cases and their age-, gender- and smoking-matched controls (N=40 matched...

journal_title：Cytokine

authors： Erdei E,Kang H,Meisner A,White K,Pickett G,Baca C,Royce M,Berwick M

更新日期：2010-07-01 00:00:00

abstract：:MERS-CoV, a highly pathogenic virus in humans, is associated with high morbidity and case fatality. Inflammatory responses have a significant impact on MERS-CoV pathogenesis and disease outcome. However, CD4+ T-cell induced immune responses during acute MERS-CoV infection are barely detectable, with potent inhibition ...

journal_title：Cytokine

authors： Alosaimi B,Hamed ME,Naeem A,Alsharef AA,AlQahtani SY,AlDosari KM,Alamri AA,Al-Eisa K,Khojah T,Assiri AM,Enani MA

更新日期：2020-02-01 00:00:00

abstract：:It is known that long-term exposure to stressful situations can produce severe consequences affecting behavioral, endocrine and immunological parameters. We have previously shown that stressed BALB/c mice had poor learning performance, which was reverted by glatiramer acetate treatment through a mechanism that likely ...

journal_title：Cytokine

authors： Palumbo ML,Di Rosso ME,Simon EH,Gonzalez Murano MR,Genaro AM

更新日期：2018-07-01 00:00:00

abstract：:Imbalance in the production of cytokines and their inhibitors plays a part in inflammation in chronic destructive diseases. Direct cell-cell contact with stimulated T cells markedly induces the production of pro-inflammatory cytokines and matrix metalloproteinases in monocytes. This study demonstrates that direct cont...

journal_title：Cytokine

authors： Vey E,Dayer JM,Burger D

更新日期：1997-07-01 00:00:00

abstract：:The pleiotropic cytokine, interleukin-6 (IL-6), has emerged in recent years as a key regulator of the transition from innate to adaptive immunity through its ability to modulate leukocyte recruitment at inflammatory sites. This review highlights a newly identified role for IL-6 trans-signaling, initiated by an agonist...

journal_title：Cytokine

authors： Vardam TD,Zhou L,Appenheimer MM,Chen Q,Wang WC,Baumann H,Evans SS

更新日期：2007-07-01 00:00:00

abstract：:Increased levels of serum IgE have been described in gliadin-intolerant patients; however, biological mechanisms implicated in this immunoglobulin production remained unknown. In this study, we demonstrated that in vitro crude gliadins and gliadin lysates (Glilys) promoted the IL-4-induced IgE production by human peri...

journal_title：Cytokine

authors： Dugas B,Dugas N,Conti M,Calenda A,Pino P,Thomas Y,Mazier D,Vouldoukis I

更新日期：2003-03-21 00:00:00

abstract：BACKGROUND:Among all cytokines involved in the pathogenesis and in the progression of psoriasis, Tumor Necrosis Factor (TNF)-alpha and interleukin (IL)-17 play a pivotal role. OBJECTIVE:The aim of the present study was to mimic a psoriatic microenvironment and to investigate the early effects of TNF-alpha and IL-17 in...

journal_title：Cytokine

authors： Donetti E,Cornaghi L,Gualerzi A,Baruffaldi Preis FW,Prignano F

更新日期：2014-07-01 00:00:00

abstract：:The authors have shown previously that in addition to its survival effects on neurons and glia, ciliary neurotrophic factor (CNTF) induced potent cachectic effects and acute phase proteins when present in the peripheral circulation at concentrations of < or = 10 ng/ml. These effects did not depend upon the induction o...

journal_title：Cytokine

authors： Henderson JT,Mullen BJ,Roder JC

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Adiponectin is an anti-atherogenic insulin-sensitizer hormone whose plasma concentration is lower in patients with metabolic syndrome (MS). Visceral adiposity, including epicardial adipose tissue (EAT), is closely related to the development of MS and coronary artery disease (CAD). We sought to study whether ...

journal_title：Cytokine

authors： Teijeira-Fernandez E,Eiras S,Shamagian LG,Somoza AS,Delgado C,Gonzalez-Juanatey JR

更新日期：2011-05-01 00:00:00

abstract：:A series of controlled clinical trials have shown that exogenous interferon-beta (IFN-β) benefits patients with relapsing-remitting multiple sclerosis (RRMS) by reducing relapse rate, disability progression, and the formation of new brain and spinal cord lesions on magnetic resonance imaging (MRI) scans. Unfortunately...

journal_title：Cytokine

authors： Huber AK,Duncker PC,Irani DN

更新日期：2015-08-01 00:00:00

abstract：:Thymic vulnerability, a leading cause of defective immunity, was discovered decades ago. To date, several strategies have been investigated to unveil any immunorestorative capacities they might confer. Studies exploiting castration, transplantation, adoptive cell therapies, hormones/growth factors, and cytokines have ...

journal_title：Cytokine

authors： El-Kadiry AE,Rafei M

更新日期：2019-08-01 00:00:00

abstract：:Toll-like receptors induce a complex inflammatory response that can function to alert the body to infection, neutralize pathogens and repair damaged tissues. Toll-like receptors are expressed on kupffer, endothelial, dendritic, biliary epithelial, hepatic stellate cells, and hepatocytes in the liver. The endoplasmic r...

journal_title：Cytokine

authors： Lawless MW,Greene CM

更新日期：2012-08-01 00:00:00

abstract：:Along with several other aspects of Chagas disease, the mechanisms responsible for the different clinical outcomes observed in chronic infected individuals have not yet been clarified. It is believed that the host immune response to the parasite plays an important role in the development of the pathology. Therefore, t...

journal_title：Cytokine

authors： de Melo AS,de Lorena VM,de Moura Braz SC,Docena C,de Miranda Gomes Y

更新日期：2012-05-01 00:00:00

abstract：:Pro-inflammatory cytokines are important mediators of cutaneous cellular activities during many skin diseases. In the present study, we investigated the production of tumor necrosis factor-alpha (TNF-alpha), IL-6 and IL-10 by UVB-irradiated human keratinocytes NCTC 2544 cell line in the presence of cAMP-elevating agen...

journal_title：Cytokine

authors： Grandjean-Laquerriere A,Le Naour R,Gangloff SC,Guenounou M

更新日期：2003-08-21 00:00:00

abstract：:The development of acidic environments is a hallmark of inflammatory processes of different etiology. We have previously shown that transient exposure to acidic conditions, similar to those encountered in vivo, induces the activation of neutrophils and the phenotypic maturation of dendritic cells. We here report that ...

journal_title：Cytokine

authors： Jancic CC,Cabrini M,Gabelloni ML,Rodríguez Rodrigues C,Salamone G,Trevani AS,Geffner J

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Owing to involvement of host genetic factors in susceptibility to brucellosis infection and its outcome, this study aimed to carry out a comprehensive systematic review and meta-analysis to derive a precise evaluation of the association between the risk of brucellosis and its focal complication and all cytoki...

journal_title：Cytokine

authors： Zafari P,Zarifian A,Alizadeh-Navaei R,Taghadosi M,Rafiei A

更新日期：2020-03-01 00:00:00

abstract：AIMS:At present, there are few studies on the relationship between circulating irisin levels and gestational diabetes mellitus (GDM), and the results are inconsistent. Therefore, this study conducts a systematic review and meta-analysis to comprehensively discuss the role of irisin in the occurrence and development of ...

journal_title：Cytokine

authors： Cui L,Qiao T,Xu F,Li Z,Chen T,Su H,Chen G,Zhang L,Xu D,Zhang X

更新日期：2020-02-01 00:00:00

abstract：:The Toll like receptors (TLRs) and the type I interferons have critical roles to play in innate immunity. In this review we will discuss new developments relating to the important area of TLR/IFN cross regulation. ...

journal_title：Cytokine

authors： Perkins DJ,Vogel SN

更新日期：2015-08-01 00:00:00

abstract：:Malignant ascites of epithelial ovarian cancer patients contains high levels of interleukin 6 (IL-6). The present study was conducted to compare the secretion of IL-6 by seven different human ovarian cancer cell lines (OVCA) and cultured human peritoneal mesothelial cells (HPMC) and to examine the regulation of its pr...

journal_title：Cytokine

authors： Offner FA,Obrist P,Stadlmann S,Feichtinger H,Klingler P,Herold M,Zwierzina H,Hittmair A,Mikuz G,Abendstein B

更新日期：1995-08-01 00:00:00

abstract：AIM:How irreversible electroporation (IRE) affect immune status is still kept unknown. This preclinical study is to investigate its local and systemic immune reaction both on tumor-bearing and tumor free animals. METHODS:Liver ablation was performed by a standard IRE instrument and proposal. Altogether 57 tumor bearin...

journal_title：Cytokine

authors： Chen X,Ren Z,Yin S,Xu Y,Guo D,Xie H,Zhou L,Wu L,Jiang J,Li H,Sun J,Zheng S

更新日期：2017-05-01 00:00:00

abstract：:Recently, a novel technique for "real time" quantitative Reverse Transcriptase-PCR which measures PCR-product accumulation during the exponential phase of the PCR reaction using a dual-labelled fluorogenic probe, has been developed. This method allows direct detection of PCR-product formation by measuring the increase...

journal_title：Cytokine

authors： Overbergh L,Valckx D,Waer M,Mathieu C

更新日期：1999-04-01 00:00:00

abstract：:Therapeutic plasmapheresis is a recognized medical procedure in which various techniques are used to separate and remove undesirable or excessively elevated plasma elements from blood. The main purpose of the procedure is to remove the substances responsible for the disease (autoantibodies, circulating immune complexe...

journal_title：Cytokine

authors： Zenti MG,Stefanutti C

更新日期：2011-12-01 00:00:00

abstract：:Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Although the pathogenesis of AD is not fully understood, we and others have shown that IL-4 plays a key role. In this study we aimed to identify keratinocyte genes regulated by IL-4 that may play important roles in the pathophysiology of AD. HaCat c...

journal_title：Cytokine

authors： Bao L,Shi VY,Chan LS

更新日期：2013-02-01 00:00:00