Abstract:
:Silicone may, like any other adjuvant, induce an inflammatory reaction and diseases. There is no data about its use in renal transplant recipients. Increased immunogenicity of silicon may manifest by activation of both the innate and the adaptive immune system cells what promotes a chronic pro-inflammatory response. Dendritic cells, macrophages, fibroblasts and T-cells have all been found at the capsule/silicone implant contact zone. Additionally, silicon may induce mononuclear cells to secrete proinflammatory cytokines IL-1β, IL-6 and TNF-α. Herein, we present two patients who developed acute rejection after breast augmentation and reconstruction with silicone-gel implants. By influencing the immunological and inflammatory response, silicone-gel may be involved in promotion of acute allograft rejection in renal transplant recipients. Further studies are needed to prove our hypothesis.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Basic-Jukic N,Ratkovic M,Radunovic D,Kastelan Zdoi
10.1016/j.mehy.2018.12.012subject
Has Abstractpub_date
2019-02-01 00:00:00pages
81-82eissn
0306-9877issn
1532-2777pii
S0306-9877(18)31217-9journal_volume
123pub_type
杂志文章abstract::Characteristics of malignant tumors, including anaerobic metabolism and metastases to lung, liver, bone and brain, may permit the enhanced survival of edited parts of the genome during periods of rapid environmental change. Carcinogenesis may be partially analogous to fossilization. ...
journal_title:Medical hypotheses
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2002-09-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章,评审
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更新日期:2017-08-01 00:00:00
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journal_title:Medical hypotheses
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更新日期:2020-04-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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pub_type: 历史文章,杂志文章
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更新日期:2004-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/s0306-9877(97)90196-1
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pub_type: 杂志文章
doi:10.1016/j.mehy.2012.04.009
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pub_type: 杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2009.08.027
更新日期:2010-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2001-05-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
pub_type: 杂志文章
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