Abstract：
:Bone is a complex material showing a hierarchical and porous structure but also a natural ability to remodel thanks to cells sensitive to fluid flows. Based on these characteristics, a multiscale numerical model has been developed in order to represent the bone response under mechanical solicitation. It relies on the homogenization technique, simulating bone as a homogeneous structure having a porous microstructure saturated with bone fluid. The numerical modeling of the loading of a finite volume of bone enables the determination of an equivalent poroelastic stiffness. Focusing on two extreme fluid boundary conditions, the study of the corresponding structural response provides an overview of the fluid contribution to the poroelastic behavior, impacting the stiffness of the considered material. This parameter is either reduced (when the fluid can flow out of the structure) or increased (when the fluid is kept inside the structure) and quantified through this model. The presented poroelastic numerical model is here developed in the perspective of providing a bio-reliable model of bones, to determine the critical parameters that might impact bone remodeling.
journal_name
J Mech Behav Biomed Materauthors
Perrin E,Bou-Saïd B,Massi Fdoi
10.1016/j.jmbbm.2018.12.015subject
Has Abstractpub_date
2019-03-01 00:00:00pages
373-382eissn
1751-6161issn
1878-0180pii
S1751-6161(18)30902-0journal_volume
91pub_type
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