Abstract:
:The ability to determine patient-specific mechanical properties of trabecular bone is needed for a reliable estimation of fracture risks. Tissue mechanics and material composition are important factors that contribute to trabecular bone performance, but only a few studies have investigated the post-yield behaviour of human trabecular bone, and limited knowledge for modelling is available about ultimate properties needed. Aim of this paper was to investigate absolute values and deviation of mechanical and material properties of human trabecular bone at the tissue level, in a healthy and osteoporotic donor. A combination of tensile and bending tests of single trabeculae up to failure, μCT measurement of sample geometry and finite element analysis were incorporated to determine mechanical properties. The samples were analysed with Raman spectroscopy to evaluate the material composition. High within-subject variability was found, for both the healthy and osteoporotic donor. Nevertheless, the two donors could be separated by analysing the ultimate strain and post-yield work, as well as two of the material parameters (B-type carbonate substitution ratio and collagen cross-link ratio). It indicates that tissue level properties seem to be relevant also for macroscopic mechanical behaviour. These findings also suggest that the mechanical variability for the inelastic region at the tissue level may be associated with varying material properties, while until yielding occurs our data does not suggest any connection between the mechanical and the investigated material. Finally, a set of mechanical properties of human bone have been reported that are a relevant reference for computational studies and FE analysis.
journal_name
J Mech Behav Biomed Materauthors
Carretta R,Stüssi E,Müller R,Lorenzetti Sdoi
10.1016/j.jmbbm.2013.04.014subject
Has Abstractpub_date
2013-08-01 00:00:00pages
64-73eissn
1751-6161issn
1878-0180pii
S1751-6161(13)00137-9journal_volume
24pub_type
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章,收录出版
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
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journal_title:Journal of the mechanical behavior of biomedical materials
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