Abstract:
:The aim of this study was to develop a biodegradable three-dimensional-printed polylactide (PLA) cage for promoting bony fixation and an antibiotics-embedded poly(d,l)-lactide-co-glycolide (PLGA) nanofibrous membrane for infectious prophylaxis during treating the comminuted metaphyseal fracture in a rabbit femoral model. The in vitro studies included measuring the mechanical properties of the 3D printed cage and determining release activities of vancomycin and ceftazidime from the nanofibers. The in vivo study included comparisons of rabbits of the femoral metaphyseal comminuted fracture treated with or without the combined biodegradable polymers. The results showed that vancomycin and ceftazidime were sustainably detected above the effective levels in the local tissue fluid around the fracture site for 3 weeks. The animal studies showed that rabbits with the 3D cage implantation possessed better cortical integrity, leg length ratio, and maximal bending strengths. The study results indicate that these combined polymers may promote fracture fixation during treating the rabbit femoral metaphyseal comminuted fracture.
journal_name
J Mech Behav Biomed Materauthors
Chou YC,Lee D,Chang TM,Hsu YH,Yu YH,Chan EC,Liu SJdoi
10.1016/j.jmbbm.2017.05.002subject
Has Abstractpub_date
2017-08-01 00:00:00pages
209-218eissn
1751-6161issn
1878-0180pii
S1751-6161(17)30190-Xjournal_volume
72pub_type
杂志文章abstract::As natural flexible dermal armor, pangolin scales provide effective protection against predatory threats and possess other notable properties such as anti-adhesion and wear-resistance. In this study, the structure, mechanical properties, deformation and damage behaviors of pangolin scales were systematically investiga...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2015.11.013
更新日期:2016-03-01 00:00:00
abstract::An optimized thickness of a transplantable auricular silicone scaffold was researched. The original image data were acquired from CT scans, and reverse modeling technology was used to build a digital 3D model of an auricle. The transplant process was simulated in ANSYS Workbench by finite element analysis (FEA), solid...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2015.08.032
更新日期:2016-01-01 00:00:00
abstract::The ability to determine patient-specific mechanical properties of trabecular bone is needed for a reliable estimation of fracture risks. Tissue mechanics and material composition are important factors that contribute to trabecular bone performance, but only a few studies have investigated the post-yield behaviour of ...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2013.04.014
更新日期:2013-08-01 00:00:00
abstract::Magnesium alloys are a promising candidate material for an emerging generation of absorbable metal stents. Due to its hexagonal-close-packed lattice structure and tendency to undergo twinning, the deformation behaviour of magnesium is quite different to that of conventional stent materials, such as stainless steel 316...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2014.01.007
更新日期:2014-06-01 00:00:00
abstract::Implants made from naturally-derived biomaterials, also called biological meshes or biomeshes, typically derive from decellularized extracellular matrix of either animal or human tissue. Biomeshes have many biomedical applications such as ligament repair, bone and cartilage regeneration and soft tissue replacement. Bo...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2017.12.003
更新日期:2018-02-01 00:00:00
abstract::A limitation in the use of hydrophilic polymers as implantable devices is their inherently poor mechanical strength. Using interpenetrating polymer networks (IPNs) consisting of both hydrophilic and hydrophobic networks is an effective method of strengthening these polymers. In this work, a series of poly(dimethyl sil...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2009.01.002
更新日期:2009-10-01 00:00:00
abstract::This study investigated the strengthening effect of glass fibers when added to conventional glass-ionomer restorative material. Glass fibers were incorporated into glass-ionomer powder in 3 wt% and 5 wt%. The fibers used had 1 mm length and 10 microm thickness. These criteria of fiber length, diameter, and concentrati...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2008.04.002
更新日期:2009-01-01 00:00:00
abstract::In the present study, inflation tests with free axial extension of 15 human vena saphena magna were conducted ex vivo to obtain data suitable for multi-axial constitutive modeling at overloading conditions (pressures up to approximately 15kPa). Subsequently the data were fitted with a hyperelastic, nonlinear and aniso...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2015.01.023
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:To evaluate the interfacial adhesion of an autopolymerizing acrylic resin to 3D printed thermoset occlusal splints compared to thermoplastic occlusal splints. MATERIALS AND METHODS:Cylinders made of an autopolymerizing acrylic resin were adhered to 3D printed thermoset and also to thermoplastic plates. A di...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2019.04.011
更新日期:2019-07-01 00:00:00
abstract::An assessment tool to evaluate the degradation of biodegradable materials in a more physiological environment is still needed. Macrophages are critical players in host response, remodeling and degradation. In this study, a cell culture model using monocyte-derived primary macrophages was established to study the degra...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2020.104077
更新日期:2020-12-01 00:00:00
abstract::Haversian remodeling is known to result in improved resistance to compressive fracture in healthy cortical bone. Here, we examine the individual roles of the mean porosity, structure of the network of pores and remodeled bone matrix properties in the fracture behavior of Haversian bone. The detailed structure of poros...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2018.04.013
更新日期:2018-07-01 00:00:00
abstract::Osteosynthesis plates are clinically used to fixate and position a fractured bone. They should have the ability to withstand cyclic loads produced by muscle contractions and total body weight. The very high demand for osteosynthesis plates in developing countries in general and in Indonesia in particular necessitates ...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2012.04.018
更新日期:2012-09-01 00:00:00
abstract::The high-performance polymer PEEK (poly-ether-ether-ketone) is more and more being used in the field of dentistry, mainly for removable and fixed prostheses. In cases of screw-retained implant-supported reconstructions of PEEK, an abutment screw made of PEEK might be advantageous over a conventional metal screw due to...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2016.06.024
更新日期:2016-10-01 00:00:00
abstract::Tissue material properties are crucial to understanding their mechanical function, both in healthy and diseased states. However, in certain circumstances logistical limitations can prevent testing on fresh samples necessitating one or more freeze-thaw cycles. To date, the nature and extent to which the material proper...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2017.03.006
更新日期:2017-07-01 00:00:00
abstract::Tissue nonlinearity is conventionally measured in shear wave elastography by studying the change in wave speed caused by the tissue deformation, generally known as the acoustoelastic effect. However, these measurements have mainly focused on the excitation and detection of one specific shear mode, while it is theoreti...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2020.103754
更新日期:2020-07-01 00:00:00
abstract::Observations of the cuticle of the Boston Spiny Lobster using scanning electron microscope (SEM) show that it is a natural biocomposite consisting of chitin fibers and sclerotic-protein matrix with hierarchical and helicoidal structure. The SEM images also indicate that there is a hole-pin joining structure in the cut...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2014.09.001
更新日期:2014-12-01 00:00:00
abstract::The use of highly sensitive soft materials has become increasingly apparent in the last few years in numerous industrial fields, due to their viscous and damping nature. Unfortunately these materials remain difficult to characterize using conventional techniques, mainly because of the very low internal forces supporte...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2016.06.008
更新日期:2016-10-01 00:00:00
abstract::The design of meshes for the treatment of incisional hernias could benefit from better knowledge of the mechanical response of the abdominal wall and how this response is affected by the implant. The aim of this study was to characterise the mechanical behaviour of the human abdominal wall. Abdominal walls were tested...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2014.07.002
更新日期:2014-10-01 00:00:00
abstract::The mechanical reliability of calcium phosphate cements has restricted their clinical application in load-bearing locations. Although their mechanical strength can be improved using a variety of strategies, their fatigue properties are still unclear, especially after degradation. The evolutions of uniaxial compressive...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2017.07.026
更新日期:2017-11-01 00:00:00
abstract::The bite force of the piranha (Serrasalmidae) has drawn considerable attention due to its ability to effectively capture and masticate prey. Herein, we analyze theoretical anterior bite forces using a lever approach and compare them to in-vivo maximum bite forces. We provide a mechanics analysis that explains the scal...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2020.104296
更新日期:2021-03-01 00:00:00
abstract::Although great progresses in the fracture mechanisms and deformation behaviors of cortical bones have been achieved, the effective methods to predict the surface fracture path of cortical bones are still difficult. By using depth-sensing nanoindentation measurement technique, the hardness distribution map of cortical ...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2020.104303
更新日期:2021-01-20 00:00:00
abstract::Polymerization shrinkage and mechanical properties affect the service life of dental restorative composites. Polyhedral oligomeric silsesquioxanes (POSS) can be an efficient strategy to improve the shrinkage properties and mechanical properties simultaneously. In this work, epoxycyclohexyl POSS (E-POSS) was used to mo...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2019.103515
更新日期:2020-03-01 00:00:00
abstract::Hydrogels are promising materials for bioengineering applications, and are good model materials for the study of hydrated biological tissues. As these materials often have a structural function, the measurement of their mechanical properties is of fundamental importance. In the present study gelatin gels reinforced wi...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2011.01.009
更新日期:2011-05-01 00:00:00
abstract::In this study, we explored the Ti-Nb-Fe system to find an optimal cost-effective composition with the lowest elastic modulus and the lowest added Nb content. Six Ti-(31-4x)Nb-(1+0.5x)Fe ingots were prepared and Nb was substituted with Fe, starting at Ti-31Nb-1.0Fe and going up to Ti-11Nb-3.5Fe (wt%). The ingots were s...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2016.09.024
更新日期:2017-01-01 00:00:00
abstract::A facile procedure has been devised to develop a novel dentin bonding system containing poly (acrylic acid)-grafted-silanized fumed silica particles as reinforcing filler, with high stability of nanoparticle dispersion and enhanced bond strength and mechanical properties. In the first step, the silanization of fumed s...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2020.103904
更新日期:2020-10-01 00:00:00
abstract::The atrioventricular heart valve (AHV) leaflets are critical to the facilitation of proper unidirectional blood flow through the heart. Previously, studies have been conducted to understand the tissue mechanics of healthy AHV leaflets to inform the development of valve-specific computational models and replacement mat...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2019.103438
更新日期:2020-01-01 00:00:00
abstract::Since the local, on demand, cancer therapy is a challenging clinical issue today, this paper presents the design, fabrication and characterization of a remotely controlled single reservoir drug delivery chip using Ionic Polymer Metal Composite (IPMC) actuator. Here, Drug release was externally programmed and controlle...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2018.06.034
更新日期:2018-10-01 00:00:00
abstract::Biocompatible polymers are commonly used to fabricate microfluidic channels for the study of biological flows such as blood microflows. The most common of these materials is polydimethylsiloxane (PDMS) which is very hydrophobic. Oxygenated plasma is advocated to treat the PDMS with reported decreases in contact angle ...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2012.07.007
更新日期:2013-01-01 00:00:00
abstract::Laser surface melting (LSM) of Ti6Al4V alloy was carried out with an aim to improve properties such as microstructure and wear for implant applications. The alloy substrate was melted at 250W and 400W at a scan velocity of 5mm/s, with input energy of 42J/mm(2) and 68J/mm(2), respectively. The results showed that equia...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2013.12.001
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:To investigate the elastic properties of human enamel using resonant ultrasound spectroscopy (RUS). METHODS:Six rectangular parallelepiped specimens were prepared from six human third molars. For all specimens, the theoretical resonant frequencies were calculated using the Rayleigh-Ritz method, knowing the ...
journal_title:Journal of the mechanical behavior of biomedical materials
pub_type: 杂志文章
doi:10.1016/j.jmbbm.2018.09.014
更新日期:2019-01-01 00:00:00