当前位置： SCI文献检索 > JOURNAL OF DIABETES AND ITS COMPLICATIONS期刊下所有文献 > The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio as a predictor of insulin resistance, β-cell function, and diabetes in Hispanics and African Americans.

The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio as a predictor of insulin resistance, β-cell function, and diabetes in Hispanics and African Americans.

Abstract：

OBJECTIVE:The TG/HDL-C ratio is used as a marker of insulin resistance (IR) in Caucasians; however, there is limited data in other ethnic groups. We hypothesized that the TG/HDL-C ratio is associated with IR in Hispanics and African Americans (AA). RESEARCH DESIGN AND METHODS:Data from the Insulin Resistance Atherosclerosis Family Study was examined for associations between TG/HDL-C ratio and IR, β-cell function and incident diabetes in non-diabetic Hispanics (n = 872, 63% female) and AA (n = 371, 61% female). Insulin sensitivity index (SI) and disposition index (DI) from frequently-sampled intravenous glucose tolerance tests were used as markers of IR and β-cell function respectively. Incident type 2 diabetes was determined by fasting glucose ≥ 126 mg/dl or initiation of anti-hyperglycemia agents over 5 year follow-up. RESULTS:Higher TG/HDL-C ratio was associated with IR in Hispanic and AA men and women (P < 0.0002), as well as β-cell function in Hispanic women and AA men and women (P < 0.02). TG/HDL-C predicted incident type 2 diabetes in women (area under the curves 0.703 and 0.795 for Hispanics and AA respectively). CONCLUSIONS:Similar to Caucasians, the TG/HDL-C ratio can be used to identify IR in Hispanics and AA, and may predict type 2 diabetes in women.

journal_name

J Diabetes Complications

journal_title

Journal of diabetes and its complications

authors

Young KA,Maturu A,Lorenzo C,Langefeld CD,Wagenknecht LE,Chen YI,Taylor KD,Rotter JI,Norris JM,Rasouli N

doi

10.1016/j.jdiacomp.2018.10.018

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

118-122

issue

2

eissn

1056-8727

issn

1873-460X

pii

S1056-8727(18)30894-8

journal_volume

33

pub_type

杂志文章

相关文献

JOURNAL OF DIABETES AND ITS COMPLICATIONS文献大全
  • Normal blood flow response and vasomotion in the diabetic Charcot foot.

    abstract：:Vasomotion, the spontaneous rhythmic contraction exhibited by small arteries and arterioles is dysregulated in patients with diabetic neuropathy. We examined the relationship between Charcot arthropathy and vasomotion at the dorsum of the foot. We studied nine diabetic patients with clinically diagnosed neuropathy and...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/s1056-8727(97)00080-9

    authors： Shapiro SA,Stansberry KB,Hill MA,Meyer MD,McNitt PM,Bhatt BA,Vinik AI

    更新日期：1998-05-01 00:00:00

  • Survival following alpha particle pituitary irradiation for diabetic retinopathy.

    abstract：:The purpose of this study was to evaluate the mortality experience of persons with longstanding diabetes who had received pituitary irradiation for diabetic retinopathy compared to a matched group of persons with diabetes who had not had pituitary ablation. The irradiated cohort consisted of 167 patients treated at th...

    journal_title：Journal of diabetes and its complications

    pub_type： 临床试验,杂志文章

    doi：10.1016/s1056-8727(97)00124-4

    authors： Klein BE,Linfoot JA,Nakagawa JS,Lee KE

    更新日期：1998-09-01 00:00:00

  • Diabetic peripheral neuropathy: effects of age, duration of diabetes, glycemic control, and vascular factors.

    abstract：:The aim of this study was to determine the factors associated with diabetic peripheral neuropathy and more particularly its relation to precisely assessed microangiopathy. Peripheral neuropathy was assessed in 135 diabetic patients: 28 insulin-dependent diabetes mellitus (IDDM), 85 non-insulin-dependent diabetes melli...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/s1056-8727(95)00086-0

    authors： Valensi P,Giroux C,Seeboth-Ghalayini B,Attali JR

    更新日期：1997-01-01 00:00:00

  • Mexican population sub-analysis of the lixilan clinical program with the fixed ratio combination of insulin glargine and lixisenatide (iGlarLixi).

    abstract：AIM:To evaluate the efficacy and safety of iGlarLixi in Mexican patients with type 2 diabetes who participated in the LixiLan clinical trials and compare results with the rest of the patients. METHODS:Data was collected for Mexican patients who participated in either of three studies: phase 2 trial LixiLan-POC, that c...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2019.05.020

    authors： González-Gálvez G,Díaz-Toscano ML,Llamas-Moreno JF,Fernández-Rodarte K,Sañudo-Maury ME

    更新日期：2020-08-01 00:00:00

  • Brain-derived neurotrophic factor correlated with muscle strength in subjects undergoing stationary bicycle exercise training.

    abstract：AIMS:Several central nervous disorders are associated with metabolic syndrome (MetS) and type 2 diabetes. Reduction in brain-derived neurotrophic factor (BDNF) is involved in the mechanism of central nervous dysfunction. BDNF is up-regulated after exercise, but it is not known whether increased BDNF is related to incre...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2015.01.014

    authors： Tsai SW,Chan YC,Liang F,Hsu CY,Lee IT

    更新日期：2015-04-01 00:00:00

  • Seasonal variability of glycated hemoglobin in a diabetic population from southern Europe.

    abstract：AIMS:To analyze the seasonal variations in A1c levels among a southern European diabetic population. METHODS:We examined all monthly-grouped A1c determinations from diabetic patients during the period 2006-2011, in a region of southern Spain. RESULTS:There were 61,329 records available. The mean A1c value was 56mmol/...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2013.04.013

    authors： Gomez-Huelgas R,Santamaria-Fernandez S,Guijarro-Merino R,Navajas-Luque F,Tinahones FJ,Roman-Teran CM,Picon MJ,Bernal-Lopez MR

    更新日期：2013-11-01 00:00:00

  • Consequences of delayed pump infusion line change in patients with type 1 diabetes mellitus treated with continuous subcutaneous insulin infusion.

    abstract：OBJECTIVE:To systematically investigate the effect of lack of adherence to the recommended change in insulin pump infusion line use beyond 48 h and determine whether the type of insulin made a difference. RESEARCH DESIGN AND METHODS:This was a double-blind, randomized, crossover trial with 20 patients with diabetes me...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jdiacomp.2009.03.002

    authors： Thethi TK,Rao A,Kawji H,Mallik T,Yau CL,Christians U,Fonseca V

    更新日期：2010-03-01 00:00:00

  • Effect of quinapril or losartan alone and in combination on left ventricular systolic and diastolic functions in asymptomatic patients with diabetic autonomic neuropathy.

    abstract：OBJECTIVE:To investigate the effect of angiotensin converting enzyme inhibition (ACE-I) or angiotensin receptor blockade (ARB), and their combination, on both diabetic autonomic neuropathy (DAN) and left ventricular (LV) diastolic dysfunction (LVDD) in asymptomatic patients with diabetes mellitus (DM). MATERIALS AND M...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jdiacomp.2005.05.002

    authors： Didangelos TP,Arsos GA,Karamitsos DT,Athyros VG,Georga SD,Karatzas ND

    更新日期：2006-01-01 00:00:00

  • Effects of structured testing versus routine testing of blood glucose in diabetes self-management: A randomized controlled trial.

    abstract：AIMS:To compare the effects of structured and routine testing regimens used in self-monitoring of blood glucose (SMBG) on glycemic control and diabetes self-management in insulin-naïve type 2 diabetes patients. METHODS:Sixty-two outpatients with insulin-naïve type 2 diabetes were randomly allocated into two less-frequ...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jdiacomp.2016.08.019

    authors： Nishimura A,Harashima SI,Fujita Y,Tanaka D,Wang Y,Liu Y,Inagaki N

    更新日期：2017-01-01 00:00:00

  • Superoxide production and LDL oxidation by diabetic neutrophils.

    abstract：:The mechanism(s) resulting in the premature atherosclerosis of diabetes is unknown. Increased phagocyte release of reactive oxygen species such as superoxide anion (O2.-), resulting in low-density lipoprotein (LDL) oxidation, could be one possible cause. The purpose of the present study was to compare the abilities of...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/1056-8727(95)00002-x

    authors： Fuller CJ,Agil A,Lender D,Jialal I

    更新日期：1996-07-01 00:00:00

  • Plerixafor stimulates adhesive activity and endothelial regeneration of endothelial progenitor cells via elevating CXCR7 expression.

    abstract：AIMS:To assess the effects of plerixafor on function and endothelial regeneration of endothelial progenitor cells (EPCs). METHODS:The proliferation and adhesion capacity of EPCs were evaluated in vitro. Furthermore, the expression levels of CXC chemokine receptor-7 (CXCR7) were detected before and after treatment with...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2020.107654

    authors： Jiang C,Li R,Ma X,Hu H,Wei L,Zhao J

    更新日期：2020-10-01 00:00:00

  • Insulin resistance since early adulthood and appendicular lean mass in middle-aged adults without diabetes: 20 years of the CARDIA study.

    abstract：AIMS:To determine the association between 20-year trajectories in insulin resistance (IR) since young adulthood and appendicular lean mass (ALM) at middle-age in adults without diabetes. METHODS:A prospective cohort study was designed among young and middle-aged US men (n = 925) and women (n = 1193). Fasting serum glu...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2018.09.011

    authors： Zhong VW,Bancks MP,Schreiner PJ,Lewis CE,Steffen LM,Meigs JB,Schrader LA,Schorr M,Miller KK,Sidney S,Carnethon MR

    更新日期：2019-01-01 00:00:00

  • Synergistic interaction between semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in diabetes: functional analysis by gene ontology.

    abstract：:Plasma semicarbazide-sensitive amine oxidase (SSAO) and angiotensin-converting enzyme (ACE) were studied for their correlation with diabetes (DM) complication. The effect of interaction between SSAO and ACE in DM complication is of interest. Studying the functional change due to interaction between SSAO and ACE is dif...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2007.02.007

    authors： Wiwanitkit V

    更新日期：2008-11-01 00:00:00

  • Relationship between dipstick positive proteinuria and albumin:creatinine ratios.

    abstract：:Currently, neither the American Diabetes Association nor the Kidney Foundation consider the results of a positive dipstick urine test for protein, a semi-quantitative measurement, in the final evaluation of diabetic nephropathy. Instead, they require a quantitative test. The object of this study was to assess whether ...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/s1056-8727(98)00017-8

    authors： Davidson MB,Smiley JF

    更新日期：1999-01-01 00:00:00

  • Changes in superoxide dismutase activities and concentrations and myeloperoxidase activities in leukocytes from patients with diabetes mellitus.

    abstract：:To investigate whether the two free-radical scavengers, Cu, Zn- and Mn-superoxide dismutase (SOD), are changed in leukocytes of diabetic patients, and the alteration of these enzymes correlates with the diabetic state, we measured the activity and concentration of these enzymes in leukocytes from diabetic patients. Bo...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/s1056-8727(99)00053-7

    authors： Uchimura K,Nagasaka A,Hayashi R,Makino M,Nagata M,Kakizawa H,Kobayashi T,Fujiwara K,Kato T,Iwase K,Shinohara R,Kato K,Itoh M

    更新日期：1999-09-01 00:00:00

  • The impact of sensory and/or sensorimotor neuropathy on lower limb muscle endurance, explosive and maximal muscle strength in patients with type 2 diabetes mellitus.

    abstract：AIMS:The purpose of this study was to investigate the impact of diabetic neuropathy (dNP) on lower limb endurance, explosive and maximal muscle strength in patients with Type 2 Diabetes Mellitus (T2DM). METHODS:Fifty-four participants, aged between 55 and 85, were enrolled in this observational comparative study. The ...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2020.107562

    authors： Van Eetvelde BLM,Lapauw B,Proot P,Vanden Wyngaert K,Celie B,Cambier D,Calders P

    更新日期：2020-06-01 00:00:00

  • Effect of oral fluid intake on urinary albumin excretion in diabetes mellitus.

    abstract：:The importance of routine screening for microalbuminuria in patients with diabetes has gained widespread acceptance. Since shortened collection times and random urine sampling facilitate outpatient testing for patients, it is necessary to establish whether a recent fluid intake might alter test results. Specifically, ...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/s1056-8727(01)00216-1

    authors： Ravikovich E,Messersmith T,Mick G,McCormick K

    更新日期：2002-07-01 00:00:00

  • The effect of radial pulse spectrum on the risk of major adverse cardiovascular events in patients with type 2 diabetes.

    abstract：:Radial pulse spectrum has been shown to correlate with coronary stenosis in patients with type 2 diabetes mellitus (T2DM). In academia, it has not been demonstrated that the radial artery pulse spectrum is an independent risk factor for major adverse cardiovascular events (MACE), including myocardial infarction, strok...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2018.10.009

    authors： Chang CW,Liao KM,Chang YT,Wang SH,Chen YC,Wang GC

    更新日期：2019-02-01 00:00:00

  • Factors involved in cardiac autonomic neuropathy in diabetic patients.

    abstract：:The role cardiac autonomic neuropathy (CAN) plays in diabetes is not well known. The aim of this study was to identify the factors involved in CAN in diabetic patients. One hundred patients, 44 insulin-dependent (IDDM) and 56 non-insulin-dependent (NIDDM), were investigated, using five standard tests. Three of these t...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/s1056-8727(97)00005-6

    authors： Valensi P,Huard JP,Giroux C,Attali JR

    更新日期：1997-05-01 00:00:00

  • Depression and incident lower limb amputations in veterans with diabetes.

    abstract：PROBLEM:Depression is associated with a higher risk of macrovascular and microvascular complications and mortality in diabetes, but whether depression is linked to an increased risk of incident amputations is unknown. We examined the association between diagnosed depression and incident non-traumatic lower limb amputat...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2010.07.002

    authors： Williams LH,Miller DR,Fincke G,Lafrance JP,Etzioni R,Maynard C,Raugi GJ,Reiber GE

    更新日期：2011-05-01 00:00:00

  • Potential role of E4orf1 protein in aging-associated impairment in glycemic control.

    abstract：:Aging constitutes a major risk factor for the development of type-2 diabetes (T2D) where glucose tolerance declines with age, resulting in a high prevalence of T2D and impaired glucose tolerance in the elderly population. Currently more than half of the 20 million U.S. adults with T2D are above the age of 60, and the ...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章,评审

    doi：10.1016/j.jdiacomp.2018.11.006

    authors： Gamage S,Reddy PH,Dhurandhar NV,Hegde V

    更新日期：2019-03-01 00:00:00

  • Combined exercise and visual gaze training improves stepping accuracy in people with diabetic peripheral neuropathy.

    abstract：INTRODUCTION:Patients with diabetes and diabetic peripheral neuropathy (DPN) place their feet with less accuracy whilst walking, which may contribute to the increased falls-risk. This study examines the effects of a multi-faceted intervention on stepping accuracy, in patients with diabetes and DPN. METHODS:Forty parti...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2019.07.001

    authors： Handsaker JC,Brown SJ,Petrovic M,Bowling FL,Rajbhandari S,Marple-Horvat DE,Boulton AJM,Reeves ND

    更新日期：2019-10-01 00:00:00

  • Poor glycemic control is associated with increased diastolic blood pressure and heart rate in children with Type 1 diabetes.

    abstract：:Although higher levels of hemoglobin A1c (HbA1c) and blood pressure precede the development of nephropathy in Type 1 diabetes (T1DM), the relationship between glycemic control and cardiovascular factors early in the course of diabetes is not clear. We conducted a retrospective study from clinic data for a 1-year perio...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/S1056-8727(03)00031-X

    authors： Torchinsky MY,Gomez R,Rao J,Vargas A,Mercante DE,Chalew SA

    更新日期：2004-07-01 00:00:00

  • Plasma NT-proBNP is independently associated with albuminuria in type 2 diabetes.

    abstract：OBJECTIVE:The aim of this study is to investigate the relationship between plasma NH2-terminal pro-brain natriuretic peptide (NT-proBNP) levels and diabetic nephropathy in type 2 diabetic patients. METHODS:The records of 983 patients with type 2 diabetes hospitalized in the Endocrinology and Metabolism Department of P...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2016.01.017

    authors： Zhou L,Cai X,Li M,Han X,Ji L

    更新日期：2016-05-01 00:00:00

  • Toll-like receptors 2 and 4 mediate hyperglycemia induced macrovascular aortic endothelial cell inflammation and perturbation of the endothelial glycocalyx.

    abstract：OBJECTIVES:Hyperglycemia-induced inflammation is central to the vascular complications in diabetes. Toll-like receptors (TLRs) are key players in regulating inflammatory responses. There are sparse data on the role of TLR2 and TLR4 in regulating human macrovascular aortic endothelial cells (HMAECs) inflammation and gly...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2016.01.014

    authors： Pahwa R,Nallasamy P,Jialal I

    更新日期：2016-05-01 00:00:00

  • Impact of differences in glucose tolerance on the prevalence of a negative insulinogenic index.

    abstract：OBJECTIVE:To determine the prevalence of a negative insulinogenic index (change in plasma insulin/change in plasma glucose from 0 to 30 min) from an oral glucose tolerance test according to glucose tolerance category. MATERIALS AND METHODS:Data from the San Antonio Heart Study (n=2494), Japanese American Community Dia...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2012.09.011

    authors： Faulenbach MV,Wright LA,Lorenzo C,Utzschneider KM,Goedecke JH,Fujimoto WY,Boyko EJ,McNeely MJ,Leonetti DL,Haffner SM,Kahn SE,American Diabetes Association GENNID Study Group.

    更新日期：2013-03-01 00:00:00

  • Risk factors for autonomic and somatic nerve dysfunction in different stages of glucose tolerance.

    abstract：AIM:The present study evaluates autonomic and somatic nerve function in different stages of glucose tolerance and its correlation with different cardio-metabolic parameters. MATERIAL AND METHODS:Four hundred seventy-eight subjects, mean age 49.3±13.7years and mean BMI 31.0±6.2kg/m2, divided according to glucose tolera...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2016.11.002

    authors： Dimova R,Tankova T,Guergueltcheva V,Tournev I,Chakarova N,Grozeva G,Dakovska L

    更新日期：2017-03-01 00:00:00

  • Using Tc-99m DMSA renal cortex scan to detect renal damage in women with type 2 diabetes.

    abstract：:Women with diabetes mellitus (DM) have urinary tract infection (UTI) more often than women without DM. It is unknown, however, what the prevalence and type of renal damage due to UTI is in these women. Therefore, in this study, we compared type 2 DM women with or without UTI history for the prevalence and type of rena...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/s1056-8727(02)00222-2

    authors： Wu HC,Chang CH,Lai MM,Lin CC,Lee CC,Kao A

    更新日期：2003-09-01 00:00:00

  • Angiotensin-converting enzyme inhibition for the treatment of moderate to severe diabetic retinopathy in normotensive Type 2 diabetic patients. A pilot study.

    abstract：:A few reports have suggested that angiotensin-converting enzyme inhibitors (ACE-I) have a beneficial effect on mild diabetic retinopathy (DR). This pilot study was carried out to determine if a small dose of an ACE-I would retard the progression of moderate to severe DR in normotensive Type 2 diabetic patients. Normot...

    journal_title：Journal of diabetes and its complications

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/s1056-8727(02)00188-5

    authors： Pradhan R,Fong D,March C,Jack R,Rezapour G,Norris K,Davidson MB

    更新日期：2002-11-01 00:00:00

  • Impact of metformin on metastases in patients with breast cancer and type 2 diabetes.

    abstract：AIM:To analyze the impact of glucose-lowering drugs on metastases in women living in Germany who have been diagnosed with breast cancer (BC) and type 2 diabetes mellitus (T2DM). METHODS:Women initially diagnosed with BC (2004-2013) were identified in the IMS Disease Analyzer database. Patients with a documentation of ...

    journal_title：Journal of diabetes and its complications

    pub_type： 杂志文章

    doi：10.1016/j.jdiacomp.2016.04.003

    authors： Jacob L,Kostev K,Rathmann W,Kalder M

    更新日期：2016-08-01 00:00:00