Chemical analysis and evaluation of antioxidant and antimicrobial activities of fruit fractions of Mauritia flexuosa L. f. (Arecaceae).

abstract：Background:This study evaluates the generalizability of an eight-station progress clinical skills examination and assesses the growth in performance for six clinical skills domains among first- and second-year medical students over four time points during the academic year. Methods:We conducted a generalizability stud...

journal_title：PeerJ

authors： Laird-Fick HS,Chang C,Wang L,Parker C,Malinowski R,Emery M,Solomon DJ

更新日期：2020-05-01 00:00:00

abstract：:In Western countries dogs and cats are the most popular pets, and people are increasingly opposed to their rearing for the fur industry. In 2007, a Regulation of the European Union (EU) banned the use and trade of dog and cat furs, but an official analytical protocol to identify them as source species was not provided...

journal_title：PeerJ

authors： Garofalo L,Mariacher A,Fanelli R,Fico R,Lorenzini R

更新日期：2018-06-05 00:00:00

abstract：BACKGROUND:Estimating volumes and masses of total body components is important for the study and treatment monitoring of nutrition and nutrition-related disorders, cancer, joint replacement, energy-expenditure and exercise physiology. While several equations have been offered for estimating total body components from M...

journal_title：PeerJ

authors： Lacoste Jeanson A,Dupej J,Villa C,Brůžek J

更新日期：2017-05-18 00:00:00

abstract：:Aerobic activity levels increase with body temperature across vertebrates. Differences in these levels, from highly active to sedentary, are reflected in their ecology and behavior. Yet, the changes in the cardiovascular system that allow for greater oxygen supply at higher temperatures, and thus greater aerobic activ...

journal_title：PeerJ

authors： Gillooly JF,Zenil-Ferguson R

更新日期：2014-04-10 00:00:00

abstract：:Atoposaurid crocodyliforms represent an important faunal component of Late Jurassic to Early Cretaceous Laurasian semi-aquatic to terrestrial ecosystems, with numerous spatiotemporally contemporaneous atoposaurids known from western Europe. In particular, the Late Jurassic of France and Germany records evidence for hi...

journal_title：PeerJ

authors： Tennant JP,Mannion PD

更新日期：2014-09-25 00:00:00

abstract：:This paper investigates the capabilities of the evolutionary fuzzy genetic (FG) approach and compares it with three neuro-fuzzy methods-neuro-fuzzy with grid partitioning (ANFIS-GP), neuro-fuzzy with subtractive clustering (ANFIS-SC), and neuro-fuzzy with fuzzy c-means clustering (ANFIS-FCM)-in terms of modeling long-...

journal_title：PeerJ

authors： Sadeghi-Niaraki A,Kisi O,Choi SM

更新日期：2020-08-14 00:00:00

abstract：Background:Lysyl oxidases (LOX) have been extensively studied in mammals, whereas properties and functions of recently found homologues in prokaryotic genomes remain enigmatic. Methods:LOX open reading frame was cloned from Haloterrigena turkmenica in an E. coli expression vector. Recombinant Haloterrigena turkmenica ...

journal_title：PeerJ

authors： Pestov NB,Kalinovsky DV,Larionova TD,Zakirova AZ,Modyanov NN,Okkelman IA,Korneenko TV

更新日期：2019-04-05 00:00:00

abstract：Background:A key step in embryo implantation is the adhesion to and invasion of the endometrium by the blastocyst trophectoderm. The envelope proteins of HERV-W and -FRD (human endogenous retrovirus-W and -FRD), syncytin-1 and syncytin-2, are mainly distributed in the placenta, and play important roles in the developme...

journal_title：PeerJ

authors： Guo L,Gu F,Xu Y,Zhou C

更新日期：2020-11-17 00:00:00

abstract：Background:Electrochemical signals play an important role in cell communication and behavior. Electrically charged ions transported across cell membranes maintain an electrochemical imbalance that gives rise to bioelectric signaling, called membrane potential or Vmem. Vmem plays a key role in numerous inter- and intrac...

journal_title：PeerJ

authors： Bhavsar MB,Cato G,Hauschild A,Leppik L,Costa Oliveira KM,Eischen-Loges MJ,Barker JH

更新日期：2019-02-08 00:00:00

abstract：:Agriculture is one of the main drivers of land conversion, and agriculture practices can impact on microbial diversity. Here we characterized the phyllosphere fungal diversity associated with Carménère grapevines under conventional and organic agricultural management. We also explored the fungal diversity present in t...

journal_title：PeerJ

authors： Castañeda LE,Miura T,Sánchez R,Barbosa O

更新日期：2018-10-29 00:00:00

abstract：Aims:The study aimed to explore factors contributing to body weight change over time in gastric cancer patients after gastrectomy, in order to find risk factors to implement nutritional intervention beforehand. Methods:A cohort of gastric cancer patients who were treated with gastrectomy from January to March 2019 at ...

journal_title：PeerJ

authors： Tian Q,Qin L,Zhu W,Xiong S,Wu B

更新日期：2020-07-10 00:00:00

abstract：Background:The microRNAs (miRNAs) have been validated as prognostic markers in many cancers. Here, we aimed at developing a miRNA-based signature for predicting the prognosis of esophagus adenocarcinoma (EAC). Methods:The RNA-sequencing data set of EAC was downloaded from The Cancer Genome Atlas (TCGA). Eighty-four pa...

journal_title：PeerJ

authors： Lan T,Lu Y,Xiao Z,Xu H,He J,Hu Z,Mao W

更新日期：2019-07-25 00:00:00

abstract：Background:Little is known regarding the toxic and therapeutic doses of amygdalin. Treatment regimens and schedules can vary between humans and animal models, and there have been reports of cyanide toxicity due to amygdalin use. Objective:The aim of this study was to evaluate the effect of different doses of amygdalin...

journal_title：PeerJ

authors： Albogami S,Hassan A,Ahmed N,Alnefaie A,Alattas A,Alquthami L,Alharbi A

更新日期：2020-05-21 00:00:00

abstract：:We present the first comprehensive review of the present and past shark and ray diversity in marine waters of Tropical America, examining the patterns of distribution in the Eastern Central Pacific (EP) and Western Central Atlantic (WA) realms. We identified the major regions of diversity and of endemism, and explored...

journal_title：PeerJ

authors： Carrillo-Briceño JD,Carrillo JD,Aguilera OA,Sanchez-Villagra MR

更新日期：2018-07-20 00:00:00

abstract：Background:"Quantile-dependent expressivity" occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g. adiponectin) is high or low relative to its distribution. We have previously shown that the heritability (h2 ) of adiposity, lipoproteins, postprandial lipemia, pulmonary function, and ...

journal_title：PeerJ

authors： Williams PT

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Assessing psychological pain has been recommended as an integral part of a comprehensive suicide risk assessment. The Psychache Scale, an established measure of psychological pain, does not specify a time frame for when pain is experienced, which may inadvertently increase the likelihood of identifying indiv...

journal_title：PeerJ

authors： Meerwijk EL,Weiss SJ

更新日期：2017-06-22 00:00:00

abstract：BACKGROUND:Preterm birth is a main determinant of neonatal mortality and morbidity and a major contributor to the overall mortality and burden of disease. However, research of the preterm birth is hindered by the imprecise definition of the clinical phenotype and complexity of the molecular phenotype due to multiple pr...

journal_title：PeerJ

authors： Bukowski R,Sadovsky Y,Goodarzi H,Zhang H,Biggio JR,Varner M,Parry S,Xiao F,Esplin SM,Andrews W,Saade GR,Ilekis JV,Reddy UM,Baldwin DA

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Periodization is an important component of resistance training programs. It is meant to improve adherence to the training regimen, allow for constant progression, help in avoiding plateaus, and reduce occurrence and severity of injuries. Previous findings regarding the effects of different periodization mode...

journal_title：PeerJ

authors： Grgic J,Mikulic P,Podnar H,Pedisic Z

更新日期：2017-08-22 00:00:00

abstract：Background:Mucoepidermoid carcinoma (MEC) is a common cancer in the oral salivary gland malignancy, which mainly occurs in the parotid gland. The aim of this study is to identify independent prognostic factors and establish a nomogram model for parotid gland mucoepidermoid carcinoma (P-MEC) patients using the National ...

journal_title：PeerJ

authors： Sun J,Sun Y,Yang F,Zhou Q,Liu W,Cheng Y,Wu X,Chen T,Li R,Huang B,Att W,Yu Y,Bi W

更新日期：2019-07-01 00:00:00

abstract：:We documented significantly increasing trends in atmospheric loading of ammonium (NH4) and nitrate/nitrite (NO2/3) and decreasing trends in total phosphorus (P) and sulfate (SO4) to Flathead Lake, Montana, from 1985 to 2004. Atmospheric loading of NO2/3 and NH4 increased by 48 and 198% and total P and SO4 decreased by...

journal_title：PeerJ

authors： Ellis BK,Craft JA,Stanford JA

更新日期：2015-03-19 00:00:00

abstract：:Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous synoviocytes from the affected stifle is an attractive cell source for tissue engineering replacement fibrocartilage. However, the diseased state of these cells may impede in vitro fibrocartilage formation. Synoviocytes from 12 osteoarthri...

journal_title：PeerJ

authors： Warnock JJ,Bobe G,Duesterdieck-Zellmer KF

更新日期：2014-09-30 00:00:00

abstract：:Analysis of calcium sparks in cardiomyocytes can provide valuable information about functional changes of calcium handling in health and disease. As a part of the calcium sparks analysis, sparks detection and characterization is necessary. Here, we describe a new open-source platform for automatic calcium sparks detec...

journal_title：PeerJ

authors： Laasmaa M,Karro N,Birkedal R,Vendelin M

更新日期：2019-03-29 00:00:00

abstract：:Recent years have seen a growing awareness of the role the immune system plays in successful cancer treatment, especially in novel therapies like immunotherapy. The characterization of the immunological composition of tumors and their micro-environment is thus becoming a necessity. In this paper we introduce a deep le...

journal_title：PeerJ

authors： Aprupe L,Litjens G,Brinker TJ,van der Laak J,Grabe N

更新日期：2019-04-10 00:00:00

abstract：:Synaptic exocytosis requires the assembly of syntaxin 1A and SNAP-25 on the plasma membrane and synaptobrevin 2 (VAMP2) on the vesicular membrane to bridge the two opposite membranes. It is believed that the three SNARE proteins assemble in steps along the dynamic assembly pathway. The C-terminus of SNAP-25 is known t...

journal_title：PeerJ

authors： Lu B

更新日期：2015-06-30 00:00:00

abstract：:Amazonian bamboo forests dominated by large woody bamboo plants in the genus Guadua cover approximately 180,000 km2 and represent a key resource for many organisms. In southwestern Amazonia, native bamboo forests differ in structure, biodiversity, and growth dynamics from other forest types in the region. However, wit...

journal_title：PeerJ

authors： Jacobs JM,von May R,Kavanaugh DH,Connor EF

更新日期：2018-07-03 00:00:00

abstract：Background:In the absence of highly effective antiviral therapies against SARS-CoV-2, it is crucial to counter the known pathophysiological causes of severe COVID-19. Evaluating the efficacy existing drugs may expedite the development of such therapeutics. Severe COVID-19 is largely the result of a dysregulated immune ...

journal_title：PeerJ

authors： Kaye AG,Siegel R

更新日期：2020-11-02 00:00:00

abstract：:Osteogenesis imperfecta (OI) is a genetic disorder that is usually caused by disturbed production of collagen type I. Depending on its severity in the patient, this disorder may create difficulties and challenges for the dental practitioner. The goal of this article is to provide guidelines based on scientific evidenc...

journal_title：PeerJ

authors： Rousseau M,Retrouvey JM,Members of the Brittle Bone Disease Consortium.

更新日期：2018-08-17 00:00:00

abstract：Background:During their long evolution, Synechocystis sp. PCC6803 developed a remarkable capacity to acclimate to diverse environmental conditions. In this study, Raman spectroscopy and Raman chemometrics tools (RametrixTM) were employed to investigate the phenotypic changes in response to external stressors and correl...

journal_title：PeerJ

authors： Tanniche I,Collakova E,Denbow C,Senger RS

更新日期：2020-03-30 00:00:00

abstract：Background:Grazing activity on periphytic mats determines mat structure and spatial heterogeneity. Spatial complexity in stream periphyton is highly divergent and may depend on the functional traits of the different primary consumers species (i.e., grazers) such as mouthpart morphology, feeding behavior, and feeding ac...

journal_title：PeerJ

authors： Katano I,Doi H

更新日期：2019-06-05 00:00:00

abstract：:As the most widely distributed snake in Eurasia, the adder (Vipera berus) has been extensively investigated in Europe but poorly understood in Asia. The Southern Altay Mountains represent the adder's southern distribution limit in Central Asia, whereas its population status has never been assessed. We conducted, for t...

journal_title：PeerJ

authors： Cui S,Luo X,Chen D,Sun J,Chu H,Li C,Jiang Z

更新日期：2016-08-16 00:00:00