Osteogenesis imperfecta: potential therapeutic approaches.

abstract：:The genus Elatine contains ca 25 species, all of which are small, herbaceous annuals distributed in ephemeral waters on both hemispheres. However, due to a high degree of morphological variability (as a consequence of their amphibious life-style), the taxonomy of this genus remains controversial. Thus, to fill this ga...

journal_title：PeerJ

authors： Sramkó G,Molnár V A,Tóth JP,Laczkó L,Kalinka A,Horváth O,Skuza L,Lukács BA,Popiela A

更新日期：2016-12-21 00:00:00

abstract：:Coastal habitats in Chile are hypothesized to support a number of diadromous fish species. The objective of this study was to document migratory life histories of native galaxiids and introduced salmonids from a wide latitudinal range in Chilean Patagonia (39-48°S). Otolith microchemistry data were analysed using a re...

journal_title：PeerJ

authors： Alò D,Correa C,Samaniego H,Krabbenhoft CA,Turner TF

更新日期：2019-01-03 00:00:00

abstract：:Some plants popularly employed for the treatment of peptic ulcers have proved to be attractive sources of new drugs. Despite extensive research, the pharmacological and toxicological potentials of these plants are not fully understood. In this context, the aim of this work was to analyze the multielemental composition...

journal_title：PeerJ

authors： Vieira LD,da Silva KT,Giarola RS,Inocente GF,Kushima H,Hiruma Lima CA,Hormaza JM

更新日期：2018-09-12 00:00:00

abstract：:Koalas (Phascolarctos cinereus) are highly specialized herbivorous marsupials that feed almost exclusively on Eucalyptus leaves, which are known to contain varying concentrations of many different toxic chemical compounds. The literature suggests that Lonepinella koalarum, a bacterium in the Pasteurellaceae family, ca...

journal_title：PeerJ

authors： Dahlhausen KE,Jospin G,Coil DA,Eisen JA,Wilkins LGE

更新日期：2020-10-20 00:00:00

abstract：:Background. Low molecular weight heparin (LMWH) is an effective anti-coagulant for thrombotic events. However, due to its predominant renal clearance, there are concerns that it might be associated with increased bleeding in patients with renal disease. Objectives. We systematically evaluated the efficacy and safety o...

journal_title：PeerJ

authors： Palamaner Subash Shantha G,Kumar AA,Sethi M,Khanna RC,Pancholy SB

更新日期：2015-03-10 00:00:00

abstract：:At the turn of February and March 2020, COVID-19 pandemic reached Europe. Many countries, including Poland imposed lockdown as a method of securing social distance between potentially infected. Stay-at-home orders and movement control within public space not only affected the touristm industry, but also the everyday l...

journal_title：PeerJ

authors： Szczepanek R

更新日期：2020-10-05 00:00:00

abstract：:As the most widely distributed snake in Eurasia, the adder (Vipera berus) has been extensively investigated in Europe but poorly understood in Asia. The Southern Altay Mountains represent the adder's southern distribution limit in Central Asia, whereas its population status has never been assessed. We conducted, for t...

journal_title：PeerJ

authors： Cui S,Luo X,Chen D,Sun J,Chu H,Li C,Jiang Z

更新日期：2016-08-16 00:00:00

abstract：:As conspicuous modular components of benthic marine habitats, gorgonian (sea fan) octocorals have perplexed taxonomists for centuries through their shear diversity, particularly throughout the Indo-Pacific. Phenotypic incongruence within and between seemingly unitary lineages across contrasting environments can provid...

journal_title：PeerJ

authors： Rowley SJ,Pochon X,Watling L

更新日期：2015-08-20 00:00:00

abstract：:Caloric restriction (CR) can trigger gorging behavior. We examined macronutrient choice and behavior in mice that gorged during restriction compared to restricted non-gorgers and controls. Fifty MF1 male mice were restricted to 75% of ad-libitum food intake (FI), while ten controls were fed ad-lib. Body mass (BM) and ...

journal_title：PeerJ

authors： Hambly C,Speakman JR

更新日期：2015-07-02 00:00:00

abstract：:Bacterial vaginosis (BV) is one of most common vaginal infections. However, its diagnosis by classical methods reveals low specificity. Our goal was to evaluate the accuracy diagnosis of 150 vaginal samples with research gold standard methods and our Peptide Nucleic Acid (PNA) probes by Fluorescence in situ Hybridizat...

journal_title：PeerJ

authors： Machado A,Castro J,Cereija T,Almeida C,Cerca N

更新日期：2015-02-17 00:00:00

abstract：:A cervical vertebra of the large, pelagic pterodactyloid pterosaur Pteranodon sp. from the Late Cretaceous Niobrara Formation of Kansas, USA is significant for its association with a tooth from the large lamniform shark, Cretoxyrhina mantelli. Though the tooth does not pierce the vertebral periosteum, the intimate ass...

journal_title：PeerJ

authors： Hone DWE,Witton MP,Habib MB

更新日期：2018-12-14 00:00:00

abstract：OBJECTIVE:The aim of our study was to identify barriers and enablers to implementation of the Xpert MTB/RIF test within Mongolia's National Tuberculosis Program. METHODS:Twenty-foursemi-structured interviews were conducted between June and September 2015 with laboratory staff and tuberculosis physicians in Mongolia's ...

journal_title：PeerJ

authors： Rendell NL,Bekhbat S,Ganbaatar G,Dorjravdan M,Pai M,Dobler CC

更新日期：2017-07-14 00:00:00

abstract：:Chronic kidney disease (CKD) is a common disease in elderly dogs. The present study aims to evaluate the efficacy of a dietary supplement containing calcium carbonate, calcium-lactate gluconate, chitosan and sodium bicarbonate in dogs with IRIS stage 3 of CKD. Twenty dogs were enrolled in the study, ten were administe...

journal_title：PeerJ

authors： Martello E,Perondi F,Capucchio MT,Biasato I,Biasibetti E,Cocca T,Bruni N,Lippi I

更新日期：2020-08-14 00:00:00

abstract：:Niche production is intended to produce premium pork, but several husbandry factors may affect the meat fatty acid composition and aroma. Fatty acid profile (by GC-FID) of raw meat and volatile compounds (by SPME-GC-MS) of cooked meat were analysed in loin samples from two pig genetic types-75% Duroc (Du) and 50% Piet...

journal_title：PeerJ

authors： Argemí-Armengol I,Villalba D,Tor M,Pérez-Santaescolástica C,Purriños L,Manuel Lorenzo J,Álvarez-Rodríguez J

更新日期：2019-07-17 00:00:00

abstract：Background:The exoskeleton of an insect could be an important factor in the success of its evolutionary process. This reaches its maximum expression in beetles, which constitute the most diversified animal taxon. The involvement in the management of environmental radiation could be one of the most important functions o...

journal_title：PeerJ

authors： Cuesta E,Lobo JM

更新日期：2019-11-25 00:00:00

abstract：:Several data loggers deployed to monitor temperature and humidity of Crocodylus acutus (American crocodile) nests in South Florida could not be located after hatching. One badly damaged data logger was retrieved, providing insight into the possible fate of the others. Using a taphonomic approach, we identified numerou...

journal_title：PeerJ

authors： Drumheller SK,Nestler JH,Hackett Farris CE,Farris SC,Mazzotti FJ

更新日期：2020-02-17 00:00:00

abstract：:Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous synoviocytes from the affected stifle is an attractive cell source for tissue engineering replacement fibrocartilage. However, the diseased state of these cells may impede in vitro fibrocartilage formation. Synoviocytes from 12 osteoarthri...

journal_title：PeerJ

authors： Warnock JJ,Bobe G,Duesterdieck-Zellmer KF

更新日期：2014-09-30 00:00:00

abstract：:Tufted Puffin (Fratercula cirrhata) populations have experienced dramatic declines since the mid-19th century along the southern portion of the species range, leading citizen groups to petition the United States Fish and Wildlife Service (USFWS) to list the species as endangered in the contiguous US. While there remai...

journal_title：PeerJ

authors： Hart CJ,Kelly RP,Pearson SF

更新日期：2018-03-22 00:00:00

abstract：:Weaning is an important event for all mammals, including young forest musk deer. However, weaning stress may cause intestinal microbiota-related disorders. Therefore, high-throughput 16S rRNA gene sequencing was applied to study the dynamic changes in intestinal microbiota during pre-weaning (10 days before weaning) a...

journal_title：PeerJ

authors： Li Y,Shi M,Zhang T,Hu X,Zhang B,Xu S,Ding J,Hu D,Liu S

更新日期：2020-04-13 00:00:00

abstract：:Hypocotyl elongation is a critical sign of seed germination and seedling growth, and it is regulated by multi-environmental factors. Light, temperature, and water potential are the major environmental stimuli, and their regulatory mechanism on hypocotyl growth has been extensively studied at molecular level. However, ...

journal_title：PeerJ

authors： Wang H,Shang Q

更新日期：2020-05-26 00:00:00

abstract：:The ubiquitin-proteasome system targets misfolded proteins for degradation. Since the accumulation of such proteins is potentially harmful for the cell, their prompt removal is important. E3 ubiquitin-protein ligases mediate substrate ubiquitination by bringing together the substrate with an E2 ubiquitin-conjugating e...

journal_title：PeerJ

authors： Boomsma W,Nielsen SV,Lindorff-Larsen K,Hartmann-Petersen R,Ellgaard L

更新日期：2016-02-25 00:00:00

abstract：Background:This systematic review aimed to investigate the psychometric properties of the school health's assessment tools in primary schools through COSMIN Risk of Bias checklist. We examined the studies that have addressed the measurement properties of school-health instruments to give a clear overview of the quality...

journal_title：PeerJ

authors： Kazemitabar M,Moghadamzadeh A,Habibi M,Hakimzadeh R,Garcia D

更新日期：2020-07-21 00:00:00

abstract：Background:Current and future changes in rainfall amount and frequency may particularly impact annual plants in desert ecosystems. The winter annual Echinops gmelinii Turcz. is widely distributed in the desert habitats of northern China and is a dominant pioneer annual plant following sand stabilization in the Tengger ...

journal_title：PeerJ

authors： Wang Y,Li X,Liu L,Zhao J,Sun J

更新日期：2019-11-29 00:00:00

abstract：:Trypophobia is a strong emotion of disgust evoked by clusters of holes or round objects (e.g., lotus seed pod). It has become increasingly popular and been studied since 2010s, mainly in the West and Japan. Considering this, trypophobia might be a modern emotion, and hence urbanization possibly plays key roles in tryp...

journal_title：PeerJ

authors： Zhu S,Sasaki K,Jiang Y,Qian K,Yamada Y

更新日期：2020-03-18 00:00:00

abstract：Purpose:To explore whether unilateral relapse of Bechet's disease-associated uveitis (BDU) causes differences in the tear proteome between the diseased and the contralateral quiescent eye and potential tear biomarkers for uveitis recurrence and disease monitoring. Method:To minimize interindividual variations, bilater...

journal_title：PeerJ

authors： Liang A,Qin W,Zhang M,Gao F,Zhao C,Gao Y

更新日期：2020-06-19 00:00:00

abstract：:In this paper, we propose a method for automatically detecting the times during which game players exhibit specific behavior, such as when players commonly show excitement, concentration, immersion, and surprise. The proposed method detects such outlying behavior based on the game players' characteristics. These chara...

journal_title：PeerJ

authors： Kim YB,Kang SJ,Lee SH,Jung JY,Kam HR,Lee J,Kim YS,Lee J,Kim CH

更新日期：2015-12-10 00:00:00

abstract：:Wildlife biologists often use grid-based designs to sample animals and generate abundance estimates. Although sampling in grids is theoretically sound, in application, the method can be logistically difficult and expensive when sampling elusive species inhabiting extensive areas. These factors make it challenging to s...

journal_title：PeerJ

authors： Harris G,Farley S,Russell GJ,Butler MJ,Selinger J

更新日期：2013-12-17 00:00:00

abstract：BACKGROUND:Algae encompass a wide array of photosynthetic organisms that are ubiquitously distributed in aquatic and terrestrial habitats. Algal species often bloom in aquatic ecosystems, providing a significant autochthonous carbon input to the deeper anoxic layers in stratified water bodies. In addition, various alga...

journal_title：PeerJ

authors： Morrison JM,Murphy CL,Baker K,Zamor RM,Nikolai SJ,Wilder S,Elshahed MS,Youssef NH

更新日期：2017-01-10 00:00:00

abstract：:Mutations that cause an error in the splicing of a messenger RNA (mRNA) can lead to diseases in humans. Various computational models have been developed to recognize the sequence pattern of the splice sites. In recent studies, Convolutional Neural Network (CNN) architectures were shown to outperform other existing mod...

journal_title：PeerJ

authors： Thanapattheerakul T,Engchuan W,Chan JH

更新日期：2020-07-06 00:00:00

abstract：:Anemones of genus Exaiptasia are used as model organisms for the study of cnidarian-dinoflagellate (genus Symbiodinium) endosymbiosis. However, while most reef-building corals harbor Symbiodinium of clade C, Exaiptasia spp. anemones mainly harbor clade B Symbiodinium (ITS2 type B1) populations. In this study, we revea...

journal_title：PeerJ

authors： Chen WN,Hsiao YJ,Mayfield AB,Young R,Hsu LL,Peng SE

更新日期：2016-08-24 00:00:00