Mice that gorged during dietary restriction increased foraging related behaviors and differed in their macronutrient preference when released from restriction.

Abstract:

:Caloric restriction (CR) can trigger gorging behavior. We examined macronutrient choice and behavior in mice that gorged during restriction compared to restricted non-gorgers and controls. Fifty MF1 male mice were restricted to 75% of ad-libitum food intake (FI), while ten controls were fed ad-lib. Body mass (BM) and FI were measured two and 24-h after food inclusion over 14-days. 'Gorging' mice were defined as those which ate over 25% of their daily FI in 2-h. The top 11 gorgers and the lowest 9 gorgers, along with 10 controls, had their behavior analysed during restriction, and were then provided with an unrestricted food choice, consisting of three diets that were high in fat, protein or carbohydrate. During restriction gorgers ate on average 51% of their daily FI in the 2-h following food introduction while the non-gorgers ate only 16%. Gorgers lost significantly more BM than non-gorgers possibly due to an increased physical activity linked to anticipation of daily food provision. Controls and non-gorgers spent most of their time sleeping. After restriction, both gorgers and non-gorgers were hyperphagic until their lost weight was regained. All 3 groups favoured high fat food. Gorgers and non-gorgers had a significantly greater high carbohydrate diet intake than controls, and gorgers also had a significantly greater high protein diet intake than non-gorgers and controls. On unrestricted food, they did not continue to gorge, although they still had a significantly greater 2-h FI than the other groups. Elevated protein intake may play an important role in the recovery of the lost lean tissue of gorgers after restriction.

journal_name

PeerJ

journal_title

PeerJ

authors

Hambly C,Speakman JR

doi

10.7717/peerj.1091

subject

Has Abstract

pub_date

2015-07-02 00:00:00

pages

e1091

issn

2167-8359

pii

1091

journal_volume

3

pub_type

杂志文章

相关文献

PeerJ文献大全
  • Whole gut microbiome composition of damselfish and cardinalfish before and after reef settlement.

    abstract::The Pomacentridae (damselfish) and Apogonidae (cardinalfish) are among the most common fish families on coral reefs and in the aquarium trade. Members of both families undergo a pelagic larvae phase prior to settlement on the reef, where adults play key roles in benthic habitat structuring and trophic interactions. Fi...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2412

    authors: Parris DJ,Brooker RM,Morgan MA,Dixson DL,Stewart FJ

    更新日期:2016-08-31 00:00:00

  • Changes in sprint performance and sagittal plane kinematics after heavy resisted sprint training in professional soccer players.

    abstract:Background:Sprint performance is an essential skill to target within soccer, which can be likely achieved with a variety of methods, including different on-field training options. One such method could be heavy resisted sprint training. However, the effects of such overload on sprint performance and the related kinetic...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.10507

    authors: Lahti J,Huuhka T,Romero V,Bezodis I,Morin JB,Häkkinen K

    更新日期:2020-12-15 00:00:00

  • Marked variations in gut microbiota and some innate immune responses of fresh water crayfish, marron (Cherax cainii, Austin 2002) fed dietary supplementation of Clostridium butyricum.

    abstract::This study aimed to investigate the effects of Clostridium butyricum as a dietary probiotic supplement in fishmeal based diet on growth, gut microbiota and immune performance of marron (Cherax cainii). Marron were randomly distributed into two different treatment groups, control and probiotic fed group. After 42 days ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7553

    authors: Foysal MJ,Nguyen TTT,Chaklader MR,Siddik MAB,Tay CY,Fotedar R,Gupta SK

    更新日期:2019-08-27 00:00:00

  • sv-callers: a highly portable parallel workflow for structural variant detection in whole-genome sequence data.

    abstract::Structural variants (SVs) are an important class of genetic variation implicated in a wide array of genetic diseases including cancer. Despite the advances in whole genome sequencing, comprehensive and accurate detection of SVs in short-read data still poses some practical and computational challenges. We present sv-c...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8214

    authors: Kuzniar A,Maassen J,Verhoeven S,Santuari L,Shneider C,Kloosterman WP,de Ridder J

    更新日期:2020-01-06 00:00:00

  • Development and application of molecular biomarkers for characterizing Caribbean Yellow Band Disease in Orbicella faveolata.

    abstract::Molecular stress responses associated with coral diseases represent an under-studied area of cnidarian transcriptome investigations. Caribbean Yellow Band Disease (CYBD) is considered a disease of Symbiodinium within the tissues of the coral host Orbicella faveolata. There is a paucity of diagnostic tools to assist in...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1371

    authors: Morgan M,Goodner K,Ross J,Poole AZ,Stepp E,Stuart CH,Wilbanks C,Weil E

    更新日期:2015-11-03 00:00:00

  • Microgeographic variation in body condition of three Mexican garter snakes in central Mexico.

    abstract:Background:Geographic variation in body size and condition can reveal differential local adaptation to resource availability or climatic factors. Body size and condition are related to fitness in garter snakes (Thamnophis), thus good body condition may increase survival, fecundity in females, and mating success in male...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6601

    authors: Valencia-Flores E,Venegas-Barrera CS,Fajardo V,Manjarrez J

    更新日期:2019-03-13 00:00:00

  • A unified simulation model for understanding the diversity of cancer evolution.

    abstract::Because cancer evolution underlies the therapeutic difficulties of cancer, it is clinically important to understand the evolutionary dynamics of cancer. Thus far, a number of evolutionary processes have been proposed to be working in cancer evolution. However, there exists no simulation model that can describe the dif...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8842

    authors: Niida A,Hasegawa T,Innan H,Shibata T,Mimori K,Miyano S

    更新日期:2020-04-08 00:00:00

  • A comparative in-silico analysis of autophagy proteins in ciliates.

    abstract::Autophagy serves as a turnover mechanism for the recycling of redundant and/or damaged macromolecules present in eukaryotic cells to re-use them under starvation conditions via a double-membrane structure known as autophagosome. A set of eukaryotic genes called autophagy-related genes (ATGs) orchestrate this highly el...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2878

    authors: Aslan E,Küçükoğlu N,Arslanyolu M

    更新日期:2017-01-17 00:00:00

  • Obesity, but not hypohydration, mediates changes in mental task load during passive heating in females.

    abstract:Background:The independent effects of hypohydration and hyperthermia on cognition and mood is unclear since the two stresses often confound each other. Further, it is unknown if obese individuals have the same impairments during hyperthermia and hypohydration that is often observed in non-obese individuals. Methods:Th...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5394

    authors: Caldwell AR,Burchfield J,Moyen NE,Tucker MA,Butts CL,Elbin RJ,Ganio MS

    更新日期:2018-08-16 00:00:00

  • Gonadal transcriptome sequencing of the critically endangered Acipenser dabryanus to discover candidate sex-related genes.

    abstract:Background:Acipenser dabryanus, an endemic Chinese species, has been listed as a first-class protected animal in China. Sturgeons are among the oldest and most primitive group of existing fish in the world and occupy a special place in the evolutionary history of fish. Thus, a study of the reproduction and sex differen...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5389

    authors: Chen Y,Liu Y,Gong Q,Lai J,Song M,Du J,Deng X

    更新日期:2018-07-27 00:00:00

  • Descriptive anatomy of the largest known specimen of Protoichthyosaurus prostaxalis (Reptilia: Ichthyosauria) including computed tomography and digital reconstruction of a three-dimensional skull.

    abstract::Ichthyosaur fossils are abundant in Lower Jurassic sediments with nine genera found in the UK. In this paper, we describe the partial skeleton of a large ichthyosaur from the Lower Jurassic (lower Sinemurian) of Warwickshire, England, which was conserved and rearticulated to form the centrepiece of a new permanent gal...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6112

    authors: Lomax DR,Porro LB,Larkin NR

    更新日期:2019-01-08 00:00:00

  • Characteristics and outcomes of hemodialysis patients with COVID-19: a retrospective single center study.

    abstract:Background:The coronavirus 19 (COVID-19) pandemic has heightened the threat to the health and lives of patients with comorbid diseases. Infection by COVID-19 is especially detrimental to patients on hemodialysis. In this study, we evaluated the clinical characteristics, laboratory findings, treatments and prognoses of ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.10459

    authors: Luo Y,Li J,Liu Z,Yu H,Peng X,Cao C

    更新日期:2020-11-26 00:00:00

  • Molecular evolution and expression divergence of three key Met biosynthetic genes in plants: CGS, HMT and MMT.

    abstract::Methionine (Met) is an essential sulfur-containing amino acid in animals. Cereal and legume crops with limiting levels of Met represent the major food and feed sources for animals. In plants, cystathionine gamma-synthase (CGS), methionine methyltransferase (MMT) and homocysteine methyltransferase (HMT) are committing ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6023

    authors: Zhao M,Wang W,Wei L,Chen P,Yuan F,Wang Z,Ying X

    更新日期:2018-12-04 00:00:00

  • Molecular phylogeny and taxonomy of the Epictia goudotii Species complex (Serpentes: Leptotyphlopidae: Epictinae) in Middle America and northern South America.

    abstract::Here we review the systematics of the threadsnakes of the Epictia goudotii Species complex in Middle and northern South America using external morphology and molecular data. Two species, Epictia goudotii and E. magnamaculata, are currently recognized from that region, but we provide evidence for recognizing, as specie...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1551

    authors: McCranie JR,Hedges SB

    更新日期:2016-01-12 00:00:00

  • Applicability of the ReproQ client experiences questionnaire for quality improvement in maternity care.

    abstract::Background. The ReproQuestionnaire (ReproQ) measures the client's experience with maternity care, following the WHO responsiveness model. In 2015, the ReproQ was appointed as national client experience questionnaire and will be added to the national list of indicators in maternity care. For using the ReproQ in quality...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2092

    authors: Scheerhagen M,van Stel HF,Tholhuijsen DJ,Birnie E,Franx A,Bonsel GJ

    更新日期:2016-07-13 00:00:00

  • Movement and ranging patterns of the Common Chaffinch in heterogeneous forest landscapes.

    abstract::The partitioning of production forests into discretely managed forest stands confronts animals with diversity in forest attributes at scales from point-level tree assemblages to distinct forest patches and range-level forest cover. We have investigated the movement and ranging patterns of male Common Chaffinches, Frin...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.368

    authors: Kubiczek K,Renner SC,Böhm SM,Kalko EK,Wells K

    更新日期:2014-06-19 00:00:00

  • Epidemiological dynamics of an urban Dengue 4 outbreak in São Paulo, Brazil.

    abstract:BACKGROUND:Dengue studies at the urban scale are scarce and required for guiding control efforts. In Brazil, the burden of dengue is high and challenges city public health administrations with limited resources. Here we studied the dynamics of a dengue epidemic in a single city. METHODS:Serum samples from dengue suspe...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1892

    authors: Villabona-Arenas CJ,de Oliveira JL,de Sousa-Capra C,Balarini K,Pereira da Fonseca CR,Zanotto PM

    更新日期:2016-04-05 00:00:00

  • The vibrating reed frequency meter: digital investigation of an early cochlear model.

    abstract::The vibrating reed frequency meter, originally employed by Békésy and later by Wilson as a cochlear model, uses a set of tuned reeds to represent the cochlea's graded bank of resonant elements and an elastic band threaded between them to provide nearest-neighbour coupling. Here the system, constructed of 21 reeds prog...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.1333

    authors: Bell A,Wit HP

    更新日期:2015-10-13 00:00:00

  • Lacosamide adjunctive therapy for partial-onset seizures: a meta-analysis.

    abstract::Background. The relative efficacy and safety of lacosamide as adjunctive therapy compared to other antiepileptic drugs has not been well established. Objective. To determine if lacosamide provides improved efficacy and safety, reduced length of hospital stay and improved quality of life compared with other anti-epilep...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.114

    authors: Sawh SC,Newman JJ,Deshpande S,Jones PM

    更新日期:2013-08-06 00:00:00

  • Bunyaviruses are common in male and female Ixodes scapularis ticks in central Pennsylvania.

    abstract::The blacklegged tick Ixodes scapularis is widely distributed in the United States and transmits multiple pathogens to humans, wildlife and domestic animals. Recently, several novel viruses in the family Bunyaviridae (South Bay virus (SBV) and Blacklegged tick phlebovirus (BTPV)) were identified infecting female I. sca...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2324

    authors: Sakamoto JM,Ng TFF,Suzuki Y,Tsujimoto H,Deng X,Delwart E,Rasgon JL

    更新日期:2016-08-11 00:00:00

  • Mesoscale spatiotemporal variability in a complex host-parasite system influenced by intermediate host body size.

    abstract:BACKGROUND:Parasites are essential components of natural communities, but the factors that generate skewed distributions of parasite occurrences and abundances across host populations are not well understood. METHODS:Here, we analyse at a seascape scale the spatiotemporal relationships of parasite exposure and host bo...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3675

    authors: Rodríguez SM,Valdivia N

    更新日期:2017-08-17 00:00:00

  • The effect of pharmacological inhibition of Serine Proteases on neuronal networks in vitro.

    abstract::Neurons are embedded in an extracellular matrix (ECM), which functions both as a scaffold and as a regulator of neuronal function. The ECM is in turn dynamically altered through the action of serine proteases, which break down its constituents. This pathway has been implicated in the regulation of synaptic plasticity ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.6796

    authors: Van De Vijver S,Missault S,Van Soom J,Van Der Veken P,Augustyns K,Joossens J,Dedeurwaerdere S,Giugliano M

    更新日期:2019-04-23 00:00:00

  • VSEARCH: a versatile open source tool for metagenomics.

    abstract:BACKGROUND:VSEARCH is an open source and free of charge multithreaded 64-bit tool for processing and preparing metagenomics, genomics and population genomics nucleotide sequence data. It is designed as an alternative to the widely used USEARCH tool (Edgar, 2010) for which the source code is not publicly available, algo...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2584

    authors: Rognes T,Flouri T,Nichols B,Quince C,Mahé F

    更新日期:2016-10-18 00:00:00

  • Transcriptomic profiling of purple broccoli reveals light-induced anthocyanin biosynthetic signaling and structural genes.

    abstract::Purple Broccoli (Brassica oleracea L. var italica) attracts growing attention as a functional food. Its purple coloration is due to high anthocyanin amounts. Light represents a critical parameter affecting anthocyanins biosynthesis. In this study, 'Purple Broccoli', a light-responding pigmentation cultivar, was assess...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.8870

    authors: Liu C,Yao X,Li G,Huang L,Xie Z

    更新日期:2020-05-05 00:00:00

  • Comparison of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in the serum of hypothyroxinemic and euthyroid dogs.

    abstract:OBJECTIVE:To determine the profile of 14 polybrominated diphenyl ethers (PBDEs) and 23 polychlorinated biphenyls (PCBs) in serum of domestic canines and whether this was predictive of thyroid hormone status. SAMPLES:Serum samples were collected from 51 client-owned dogs visiting the University of California Davis Will...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.3780

    authors: Lau G,Walter K,Kass P,Puschner B

    更新日期:2017-09-12 00:00:00

  • Assessment of antioxidant properties of membrane ultrafiltration peptides from mungbean meal protein hydrolysates.

    abstract:Background:Bioactive peptides can prevent damage associated with oxidative stress in humans when consumed regularly. Recently, peptides have attracted immense interest because of their beneficial functional properties, safety and little or no side effects when used at high concentration. Most antioxidant peptides are s...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.5337

    authors: Sonklin C,Laohakunjit N,Kerdchoechuen O

    更新日期:2018-07-27 00:00:00

  • Population connectivity and larval dispersal of the exploited mangrove crab Ucides cordatus along the Brazilian coast.

    abstract:Background:The mangrove crab Ucides cordatus is considered a key species for the ecological balance of mangrove forests and a major source of employment and income for traditional crab collectors in Brazil. Several studies evidenced weak genetic variation among populations due to an efficient larval transport. However,...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.4702

    authors: Britto FB,Schmidt AJ,Carvalho AMF,Vasconcelos CCMP,Farias AM,Bentzen P,Diniz FM

    更新日期:2018-04-30 00:00:00

  • Life history and past demography maintain genetic structure, outcrossing rate, contemporary pollen gene flow of an understory herb in a highly fragmented rainforest.

    abstract:INTRODUCTION:Theory predicts that habitat fragmentation, by reducing population size and increasing isolation among remnant populations, can alter their genetic diversity and structure. A cascade of effects is expected: genetic drift and inbreeding after a population bottleneck, changes in biotic interactions that may ...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2764

    authors: Suárez-Montes P,Chávez-Pesqueira M,Núñez-Farfán J

    更新日期:2016-12-22 00:00:00

  • Geriatric syndromes are potential determinants of the medication adherence status in prevalent dialysis patients.

    abstract::Background. Geriatric syndromes (GS) exhibit high prevalence in patients with end-stage renal disease (ESRD) under chronic dialysis irrespective of age. We sought to determine whether GS influences medication adherence in ESRD patients. Methods. A prospective cohort of chronic dialysis patients was assembled. The pres...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.2122

    authors: Chao CT,Huang JW,COGENT (COhort of GEriatric Nephrology in NTUH) study group.

    更新日期:2016-06-14 00:00:00

  • An enigmatic decoupling between heat stress and coral bleaching on the Great Barrier Reef.

    abstract::Ocean warming threatens the functioning of coral reef ecosystems by inducing mass coral bleaching and mortality events. The link between temperature and coral bleaching is now well-established based on observations that mass bleaching events usually occur when seawater temperatures are anomalously high. However, times...

    journal_title:PeerJ

    pub_type: 杂志文章

    doi:10.7717/peerj.7473

    authors: DeCarlo TM,Harrison HB

    更新日期:2019-08-12 00:00:00