sv-callers: a highly portable parallel workflow for structural variant detection in whole-genome sequence data.

abstract：:One of the best ex situ conservation strategies for wild germplasm is in vitro conservation of genetic banks. The success of in vitro conservation relies heavily on the micropropagation or performance of the species of interest. In the context of global change, crop production challenges and climate change, we face a ...

journal_title：PeerJ

authors： Hernández-Terán A,Wegier A,Benítez M,Lira R,Sosa Fuentes TG,Escalante AE

更新日期：2019-06-10 00:00:00

abstract：:Multimodal imaging enables sensitive measures of the architecture and integrity of the human brain, but the high-dimensional nature of advanced brain imaging features poses inherent challenges for the analyses and interpretations. Multivariate age prediction reduces the dimensionality to one biologically informative s...

journal_title：PeerJ

authors： Richard G,Kolskår K,Sanders AM,Kaufmann T,Petersen A,Doan NT,Monereo Sánchez J,Alnæs D,Ulrichsen KM,Dørum ES,Andreassen OA,Nordvik JE,Westlye LT

更新日期：2018-11-30 00:00:00

abstract：BACKGROUND:Digital medicine and smartphone-enabled health technologies provide a novel source of human health and human biology data. However, in part due to its intricacies, few methods have been established to analyze and interpret data in this domain. We previously conducted a six-month interventional trial examinin...

journal_title：PeerJ

authors： Gollamudi SS,Topol EJ,Wineinger NE

更新日期：2016-08-02 00:00:00

abstract：:The INDETERMINATE DOMAIN (IDD) gene family encodes hybrid transcription factors with distinct zinc finger motifs and appears to be found in all higher plant genomes. IDD genes have been identified throughout the genomes of the model plants Arabidopsis thaliana and Oryza sativa, and the functions of many members of thi...

journal_title：PeerJ

authors： Su X,Meng T,Zhao Y,Li G,Cheng X,Abdullah M,Sun X,Cai Y,Lin Y

更新日期：2019-03-26 00:00:00

abstract：:Although liver cirrhosis and hepatocellular carcinoma are major consequences of hepatitis C (HCV), there has been an increasing number of studies examining extrahepatic manifestations, especially those caused by systemic chronic inflammation and metabolic complications that might predispose HCV patients to atheroscler...

journal_title：PeerJ

authors： Pavicic Ivelja M,Dolic K,Tandara L,Perkovic N,Mestrovic A,Ivic I

更新日期：2021-01-14 00:00:00

abstract：Background:Medicare is one of the world's largest health insurance programs. It provides health insurance to nearly 44 million beneficiaries whose entitlements are based on age, disability, or end-stage renal disease (ESRD). Data of these ESRD beneficiaries are collected in the US Renal Data System (USRDS), which inclu...

journal_title：PeerJ

authors： Mu Y,Chin AI,Kshirsagar AV,Bang H

更新日期：2018-07-27 00:00:00

abstract：:Metabolic dysfunction in skeletal muscle is a major contributor to the development of type 2 diabetes. Endurance exercise training has long been established as an effective means to directly restore skeletal muscle glucose and lipid uptake and metabolism. However, in addition to the direct effects of skeletal muscle o...

journal_title：PeerJ

authors： Peterson JM,Mart R,Bond CE

更新日期：2014-09-30 00:00:00

abstract：:MicoRNAs (miRNAs), usually as gene regulators, participate in various biological processes, including stress responses. The hypothalamus-pituitary-adrenal axis (HPA axis) is an important pathway in regulating stress response. Although the mechanism that HPA axis regulates stress response has been basically revealed, t...

journal_title：PeerJ

authors： Luo W,Fang M,Xu H,Xing H,Fu J,Nie Q

更新日期：2016-02-18 00:00:00

abstract：:We describe a new species of Oligodon from the highlands of the Langbian Plateau, southern Truong Son Mountains, Vietnam, based on morphological and molecular phylogenetic analyses. The new species, Oligodon rostralissp. nov is distinguished from its congeners by the following morphological characters: medium size in ...

journal_title：PeerJ

authors： Nguyen HN,Tran BV,Nguyen LH,Neang T,Yushchenko PV,Poyarkov NA

更新日期：2020-01-06 00:00:00

abstract：Background:In this study cull dairy cows from six California dairy herds were sampled seasonally over the course of a year. The objectives were to determine the prevalence of antimicrobial resistant (AMR) Salmonella spp. shed in cull cow feces, and the factors associated with fecal shedding of AMR and multidrug resista...

journal_title：PeerJ

authors： Pereira R,Williams DR,Rossitto P,Adaska J,Okello E,Champagne J,Lehenbauer TW,Li X,Chase J,Nguyen T,Pires AFA,Atwill ER,Aly SS

更新日期：2019-03-21 00:00:00

abstract：:According to Spearman's law of diminishing returns (SLODR), IQ test scores are more g saturated among those with low, compared to those with high, ability. The present simulation shows that such difference in saturation can be observed if test scores are affected by a disturbing factor, for example, low motivation, il...

journal_title：PeerJ

authors： Sorjonen K,Melin B

更新日期：2020-07-03 00:00:00

abstract：Background:Experiencing an adequate amount of cold temperatures over winter is necessary for many temperate tree species to break dormancy and flower in spring. Thus, changes in winter and spring temperatures associated with climate change may influence when trees break dormancy and flower in the future. There have bee...

journal_title：PeerJ

authors： Prevéy JS,Harrington CA

更新日期：2018-09-25 00:00:00

abstract：:In highly biodiverse systems, such as coral reefs, prey species are faced with predatory threats from numerous species. Recognition of predators can be innate, or learned, and can help increase the chance of survival. Research suggests that parental exposure to increased predatory threats can affect the development, b...

journal_title：PeerJ

authors： Atherton JA,McCormick MI

更新日期：2020-06-18 00:00:00

abstract：:Weevils (Coleoptera: Curculionoidea) represent one of the most diverse groups of organisms on Earth; interactions with their host plants have been recognized to play a central role in their remarkable diversity, yet the exact mechanisms and factors still remain poorly understood. Using phylogenetic comparative analyse...

journal_title：PeerJ

authors： Hernández-Vera G,Toševski I,Caldara R,Emerson BC

更新日期：2019-03-20 00:00:00

abstract：Background:Vegetation in the Mongolian Plateau is very sensitive to climate change, which has a significant impact on the regulation of terrestrial carbon cycle. Methods:We analyzed spatio-temporal changes of both growing season and the seasonal Normalized Difference Vegetation Index (NDVI) using simple linear trend a...

journal_title：PeerJ

authors： Meng M,Huang N,Wu M,Pei J,Wang J,Niu Z

更新日期：2019-09-30 00:00:00

abstract：Background:Inhibition processing is sensitive to aging, and an age-related decline in inhibition processing has been associated with an accelerated rate of progression to Alzheimer disease. Elderly women are two to three times more likely than age-matched men to have Alzheimer disease. Therefore, this study examined wh...

journal_title：PeerJ

authors： Xu C,Lu Y,Wang B,Zhou C

更新日期：2019-03-18 00:00:00

abstract：:Local ancestry estimation infers the regional ancestral origin of chromosomal segments in admixed populations using reference populations and a variety of statistical models. Integrating local ancestry into complex trait genetics has the potential to increase detection of genetic associations and improve genetic predi...

journal_title：PeerJ

authors： Schubert R,Andaleon A,Wheeler HE

更新日期：2020-10-02 00:00:00

abstract：:Freshwater food webs are dominated by aquatic invertebrates whose trophic relationships are often poorly known. Here, I used laboratory experiments to study the role of a water bug, Sigara striata, as a potential predator and prey in food webs of stagnant waters. Multiple-choice predation experiment revealed that Siga...

journal_title：PeerJ

authors： Klecka J

更新日期：2014-05-22 00:00:00

abstract：:Changes in behavior are often the proximate response of animals to human disturbance, with variability in tolerance levels leading some species to exhibit striking shifts in life history, fitness, and/or survival. Thus, elucidating the effects of disturbance on animal behavior, and how this varies among taxonomically ...

journal_title：PeerJ

authors： Matich P,Schalk CM

更新日期：2019-06-07 00:00:00

abstract：Background:This systematic review aimed to investigate the psychometric properties of the school health's assessment tools in primary schools through COSMIN Risk of Bias checklist. We examined the studies that have addressed the measurement properties of school-health instruments to give a clear overview of the quality...

journal_title：PeerJ

authors： Kazemitabar M,Moghadamzadeh A,Habibi M,Hakimzadeh R,Garcia D

更新日期：2020-07-21 00:00:00

abstract：:Acoustic recording has been recognized as a valuable tool for non-intrusive monitoring of the marine environment, complementing traditional visual surveys. Acoustic surveys conducted on coral ecosystems have so far been restricted to barrier reefs and to shallow depths (10-30 m). Since they may provide refuge for cora...

journal_title：PeerJ

authors： Bertucci F,Parmentier E,Berthe C,Besson M,Hawkins AD,Aubin T,Lecchini D

更新日期：2017-11-14 00:00:00

abstract：:In agricultural landscape, there are thousands of young wild animals killed every year. Their deaths are caused mostly by agricultural fieldworks during spring harvest. Among the affected animals there are also fawns of roe deer (Capreolus capreolus), which react to danger by pressing themselves against the ground in ...

journal_title：PeerJ

authors： Cukor J,Bartoška J,Rohla J,Sova J,Machálek A

更新日期：2019-05-10 00:00:00

abstract：:Arbuscular mycorrhizal fungi (AMF) colonization, sampled at 32-50 days post-inoculation (dpi), was significantly reduced in suppressor of prosystemin-mediated responses2 (spr2) mutant tomato plants impaired in the ω-3 FATTY ACID DESATURASE7 (FAD7) gene that limits the generation of linolenic acid and, consequently, th...

journal_title：PeerJ

authors： Casarrubias-Castillo K,Montero-Vargas JM,Dabdoub-González N,Winkler R,Martinez-Gallardo NA,Zañudo-Hernández J,Avilés-Arnaut H,Délano-Frier JP

更新日期：2020-04-16 00:00:00

abstract：Background:Geographic variation in body size and condition can reveal differential local adaptation to resource availability or climatic factors. Body size and condition are related to fitness in garter snakes (Thamnophis), thus good body condition may increase survival, fecundity in females, and mating success in male...

journal_title：PeerJ

authors： Valencia-Flores E,Venegas-Barrera CS,Fajardo V,Manjarrez J

更新日期：2019-03-13 00:00:00

abstract：:Inflammation is critical in the dysregulated growth of adipose tissue and associated vascular dysfunctions. 15-Lipoxygenase metabolites, important mediators of inflammation in adipose tissue during obese conditions, may contribute to codependence of inflammation and angiogenesis in adipose tissue. We have already repo...

journal_title：PeerJ

authors： Soumya SJ,Binu S,Helen A,Reddanna P,Sudhakaran PR

更新日期：2014-10-21 00:00:00

abstract：:Combination Index (CI) analysis suggested that MBIC and doxorubicin synergistically inhibited up to 97% of cell proliferation in ER+/PR+MCF-7 and triple negative MDA-MB-231 breast cancer cell lines. Moreover, treatment of the breast cancer cells with the combined drugs resulted in lower IC50 values in contrast to the ...

journal_title：PeerJ

authors： Hasanpourghadi M,Abdul Majid N,Rais Mustafa M

更新日期：2018-09-17 00:00:00

abstract：:The purpose of the study was to investigate the relationship between different exercise modes and visuospatial working memory in healthy older adults. A cross-sectional design was adopted. A total of 111 healthy older adults were enrolled in the study. They were classified by the exercise-related questionnaire to be i...

journal_title：PeerJ

authors： Guo W,Wang B,Lu Y,Zhu Q,Shi Z,Ren J

更新日期：2016-07-20 00:00:00

abstract：:We explored the genetic background of social interactions in two breeding metapopulations of the pied flycatcher (Ficedula hypoleuca) in Western Siberia. In 2005, we sampled blood from birds breeding in study areas located in the city of Tomsk and in a natural forest 13 km southward of Tomsk (Western Siberia, Russia)....

journal_title：PeerJ

authors： Grinkov VG,Bauer A,Gashkov SI,Sternberg H,Wink M

更新日期：2018-12-06 00:00:00

abstract：Background:Fibroblast growth factor 2 (FGF2) is a highly pleiotropic cytokine with antifibrotic activity in wound healing. During the process of wound healing and fibrosis, fibroblasts are the key players. Although accumulating evidence has suggested the antagonistic effects of FGF2 in the activation process of fibrobl...

journal_title：PeerJ

authors： Wu B,Tang X,Zhou Z,Ke H,Tang S,Ke R

更新日期：2021-01-15 00:00:00

abstract：Background:Cities face rapid changes leading to increasing inequalities and emerging public health issues that require cost-effective interventions. The urban exposome concept refers to the continuous monitoring of urban environmental and health indicators using the city and smaller intra-city areas as measurement unit...

journal_title：PeerJ

authors： Andrianou XD,van der Lek C,Charisiadis P,Ioannou S,Fotopoulou KN,Papapanagiotou Z,Botsaris G,Beumer C,Makris KC

更新日期：2019-05-24 00:00:00