Abstract：
:It is widely held that transdiaphragmatic pressure is a reliable index of the extent of central activation of the diaphragm but the maximal voluntary transdiaphragmatic pressure is lower during inspiratory than expulsive efforts. To determine whether the diaphragm is fully activated during the two manoeuvres supramaximal stimuli were delivered to both phrenic nerves during maximal efforts. No discernible twitch was evoked during 30-55% of attempted maximal efforts with either voluntary manoeuvre. Thus the difference in maximal transdiaphragmatic pressure between the manoeuvres must reflect changes in chest-wall geometry or mechanics rather than in the phrenic motor outflow. Inspiratory intercostal muscle activity was consistently submaximal during maximal inspiratory efforts.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
McKenzie DK,Plassman BL,Gandevia SCdoi
10.1016/0304-3940(88)90481-8subject
Has Abstractpub_date
1988-06-17 00:00:00pages
63-8issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(88)90481-8journal_volume
89pub_type
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