Upregulation of long noncoding RNA XIST is associated with poor prognosis in human cancers.

abstract：:The components of 45calcium (Ca) uptake were studied in saponin skinned rat caudal artery. The steady-state Ca content increased when the free Ca concentration was varied from 10(-8) to 10(-4) M but was reduced by azide when the free Ca concentration exceeded 3.1 microM. The azide sensitivity and low affinity for Ca w...

journal_title：Journal of cellular physiology

authors： Stout MA

更新日期：1991-12-01 00:00:00

abstract：:Both mammary gland development and mammary carcinogenesis involve extensive remodeling of the mammary gland extracellular matrix. The expression of four membrane-type matrix metalloproteinases (MT-MMPs) with matrix remodeling potential in development and tumorigenesis was evaluated by in-situ hybridization on mouse ma...

journal_title：Journal of cellular physiology

authors： Szabova L,Yamada SS,Birkedal-Hansen H,Holmbeck K

更新日期：2005-10-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is one of the main liver diseases today, and may progress to steatohepatitis, cirrhosis, and hepatocellular carcinoma. Some studies have shown the beneficial effects of aerobic exercise on reversing NAFLD. To verify whether chronic aerobic exercise improves the insulin resistan...

journal_title：Journal of cellular physiology

authors： Batatinha HA,Lima EA,Teixeira AA,Souza CO,Biondo LA,Silveira LS,Lira FS,Rosa Neto JC

更新日期：2017-05-01 00:00:00

abstract：:During the early period after poliovirus infection of HeLa cells, cellular Na+/K+ ATPase activity is transiently activated. We investigated the possibility that Na+/K+ ATPase activation is a consequence of Na+/H+ antiporter activation. Increased uptake of the weak organic acid 5,5-dimethyloxazolidine-2,4-dione by infe...

journal_title：Journal of cellular physiology

authors： Holsey C,Cragoe EJ Jr,Nair CN

更新日期：1990-03-01 00:00:00

abstract：:Differentiation commitment events are essential for the initiation of hemopoiesis and, in one form or another, occur continuously during adult hemopoiesis. The most studied type of differentiation commitment decision a hemopoietic cell can make involves the alternative choice of self-renewal versus the formation of pr...

journal_title：Journal of cellular physiology

authors： Metcalf D,Nicola NA,Robb L

更新日期：1997-11-01 00:00:00

abstract：:The effects of the polyamines putrescine (PUT), spermidine (SPD), and spermidine (SPM) on the secretion of plasminogen activator (PA) and plasminogen activator inhibitor (PAI) were evaluated using cultured bovine aortic endothelial cells. All three polyamines enhanced PA secretion in a time- and dose-dependent manner,...

journal_title：Journal of cellular physiology

authors： Kuo BS,Korner G,Dryjski M,Bjornsson TD

更新日期：1988-10-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) have been shown to have critical regulatory roles in tumorigenesis. lncRNA LINC01561 (LINC01561) is a newly identified tumor-related lncRNA and its dysregulation has been demonstrated in several tumors. However, whether LINC01561 is involved in the progression of non-small-cell lung carci...

journal_title：Journal of cellular physiology

authors： Gao W,Qi CQ,Feng MG,Yang P,Liu L,Sun SH

更新日期：2020-10-01 00:00:00

abstract：:Stromal cell-derived factor-1 (SDF-1) and CXC chemokine receptor 4 (CXCR4) have been found to be tightly correlated with the progression of prostate cancer (PC). In this study, we investigated the effects of an SDF-1α/CXCR4 inhibitor, AMD3100, on cell progression and metastasis potential of human PC cells. Human PC ce...

journal_title：Journal of cellular physiology

authors： Zhu WB,Zhao ZF,Zhou X

更新日期：2019-07-01 00:00:00

abstract：:Exposure of cultured endothelial cells to endotoxin causes an increase in the amount of cellular heparan sulfate proteoglycan and a depletion of this molecule in the extracellular matrix. Concomitant with the decrease in the extracellular matrix is the appearance of a fraction of proteoglycan bearing altered carbohydr...

journal_title：Journal of cellular physiology

authors： Colburn P,Kobayashi E,Buonassisi V

更新日期：1994-04-01 00:00:00

abstract：:Comparative studies with rat transferrin (rTf) and asialotransferrin (asialo-rTf) were performed on suspended adult rat hepatocytes with the aim of elucidating the mechanism of enhanced hepatic Fe acquisition from asialo-rTf observed previously in vivo. At low ligand concentrations (0.05-20 micrograms/ml), the cells b...

journal_title：Journal of cellular physiology

authors： Rudolph JR,Regoeczi E

更新日期：1988-06-01 00:00:00

abstract：:Insulin-like growth factor-I (IGF-I) (13 nM) can replace insulin (0.8 microM) in a serum-free medium containing epidermal growth factor (EGF) (16 nM) and dexamethasone (DEX) (140 nM) and stimulate DNA synthesis in young cultures of WI-38 cells, similar to the stimulation of serum-supplemented medium. By contrast, sene...

journal_title：Journal of cellular physiology

authors： Phillips PD,Pignolo RJ,Cristofalo VJ

更新日期：1987-10-01 00:00:00

abstract：:CRM197 is a naturally nontoxic diphtheria toxin mutant that binds and inhibits heparin-binding epidermal growth factor-like growth factor. CRM197 serves as carrier protein for vaccine and other therapeutic agents. CRM197 also inhibits the growth, migration, invasion, and induces apoptosis in various tumors. Vascular c...

journal_title：Journal of cellular physiology

authors： Hu Y,Lin X,Wang P,Xue YX,Li Z,Liu LB,Yu B,Feng TD,Liu YH

更新日期：2015-08-01 00:00:00

abstract：:Wound healing is critically affected by age, ischemia, and growth factors such as TGFbeta1. The combined effect of these factors on fibroblast migration, an essential component of wound healing, is poorly understood. To address this deficiency, we examined expression of TGFbeta receptor type I and II (TGFbetaRI and RI...

journal_title：Journal of cellular physiology

authors： Mogford JE,Tawil N,Chen A,Gies D,Xia Y,Mustoe TA

更新日期：2002-02-01 00:00:00

abstract：:Subcellular localization of the large multicatalytic protease complexes called proteasomes, which have been found in soluble fractions of various cells, was examined by biochemical, immunological, and immunohistological methods. Rat liver nuclei, purified by two different procedures, showed high activities for degradi...

journal_title：Journal of cellular physiology

authors： Tanaka K,Kumatori A,Ii K,Ichihara A

更新日期：1989-04-01 00:00:00

abstract：:Increased vascular resistance in the fetoplacental circulation is a characteristic of preeclampsia. However, the potential molecular mechanisms of this condition remain obscure. The current study aimed to determine the direct effect of the peptide antigen corresponding to the second extracellular loop of the angiotens...

journal_title：Journal of cellular physiology

authors： Zhang S,Zheng R,Yang L,Zhang X,Zuo L,Yang X,Bai K,Song L,Tian J,Yang J,Liu H

更新日期：2013-01-01 00:00:00

abstract：:We have previously shown that knockout of fibroblast growth factor-2 (FGF-2) and potential compensatory effects of other growth factors result in amelioration of disease symptoms in a transgenic mouse model of amyotrophic lateral sclerosis (ALS). ALS is a rapidly progressive neurological disorder leading to degenerati...

journal_title：Journal of cellular physiology

authors： Kefalakes E,Böselt S,Sarikidi A,Ettcheto M,Bursch F,Naujock M,Stanslowsky N,Schmuck M,Barenys M,Wegner F,Grothe C,Petri S

更新日期：2019-05-01 00:00:00

abstract：:Maintenance of intestinal epithelial barrier functions is crucial to prevent systemic contamination by microbes that penetrate from the gut lumen. GTPases of the Rho-family such as RhoA, Rac1, and Cdc42 are known to be critically involved in the regulation of intestinal epithelial barrier functions. However, it is sti...

journal_title：Journal of cellular physiology

authors： Schlegel N,Meir M,Spindler V,Germer CT,Waschke J

更新日期：2011-05-01 00:00:00

abstract：:Impaired cardiac control of intracellular diastolic Ca(2+) gives rise to arrhythmias. Whereas exercise training corrects abnormal cyclic Ca(2+) handling in heart failure, the effect on diastolic Ca(2+) remains unstudied. Here, we studied the effect of exercise training on the generation and propagation of spontaneous ...

journal_title：Journal of cellular physiology

authors： Kemi OJ,MacQuaide N,Hoydal MA,Ellingsen O,Smith GL,Wisloff U

更新日期：2012-01-01 00:00:00

abstract：:A proliferation inducing ligand (APRIL or TALL-2 and TRDL-1) was first discovered as a cytokine over-expressed in many transformed cells and with the capacity to stimulate proliferation. APRIL was shown to bind two different receptors of the TNF receptor superfamily: B cell maturation antigen (BCMA) and transmembrane ...

journal_title：Journal of cellular physiology

authors： Kimberley FC,Hahne M,Medema JP

更新日期：2009-01-01 00:00:00

abstract：:p53-mediated apoptosis involves multiple mechanisms. A number of p53-regulated apoptosis-related genes have been identified. Some of these genes encode proteins that are important in controlling the integrity of mitochondria while the others code for membrane death receptors. p53 may also induce apoptosis by interferi...

journal_title：Journal of cellular physiology

authors： Sheikh MS,Fornace AJ Jr

更新日期：2000-02-01 00:00:00

abstract：:Nucleoside transporter proteins are specialized proteins that mediate the transport of nucleosides and nucleoside analog drugs across the plasma membrane. The human equilibrative nucleoside transporter 1 (hENT1) is a member of these proteins and mediates cellular entry of gemcitabine, cytarabine, and fludarabine. The ...

journal_title：Journal of cellular physiology

authors： Santini D,Vincenzi B,Fratto ME,Perrone G,Lai R,Catalano V,Cass C,Ruffini PA,Spoto C,Muretto P,Rizzo S,Muda AO,Mackey JR,Russo A,Tonini G,Graziano F

更新日期：2010-05-01 00:00:00

abstract：:Deep vein thrombosis associated with advanced cancer is known as Trousseau's syndrome. We hypothesized that thrombin, an activator of protease-activated receptor (PAR)-1 and PAR-4 contributes to tumor metastasis. In this study, we demonstrated that thrombin and the PAR-1 activating peptide (AP) SFLLRN, but not the PAR...

journal_title：Journal of cellular physiology

authors： Chang LH,Chen CH,Huang DY,Pai HC,Pan SL,Teng CM

更新日期：2011-04-01 00:00:00

abstract：:The antibody-secreting murine hybridoma, CC9C10, was grown in batch culture in a medium containing 20 mM glucose and 2 mM glutamine. After 2 days of exponential growth, the glutamine content of the medium was completely depleted, whereas the glucose content was reduced to 60% of the original concentration. The glucose...

journal_title：Journal of cellular physiology

authors： Petch D,Butler M

更新日期：1994-10-01 00:00:00

abstract：:During human pregnancy, the trophoblast develops from differentiation of cytotrophoblast cells into an endocrine active syncytiotrophoblast. In culture, isolated mononuclear cytotrophoblasts aggregate and then fuse to form a syncytium, reproducing the in vivo process. In this study, we examined the effect of low oxyge...

journal_title：Journal of cellular physiology

authors： Alsat E,Wyplosz P,Malassiné A,Guibourdenche J,Porquet D,Nessmann C,Evain-Brion D

更新日期：1996-08-01 00:00:00

abstract：:The purpose of this study was to characterize the direct effects of uncarboxylated osteocalcin (ucOCN) on vascular cell biology in vitro, to assess its potential function in pathophysiological conditions such as atherosclerosis. Human aortic endothelial cells (HAECs) and smooth muscle cells (HASMCs) were treated with ...

journal_title：Journal of cellular physiology

authors： Millar SA,Anderson SI,O'sullivan SE

更新日期：2019-11-01 00:00:00

abstract：:Ankylosing spondylitis (AS) is a chronic immune-mediated inflammatory disease that affects both axial and peripheral skeletons as well as soft tissues. Recent investigations offer that disease pathogenesis is ascribed to a complex interplay of genetic, environmental, and immunological factors. Until now, there is no a...

journal_title：Journal of cellular physiology

authors： Mohammadi H,Hemmatzadeh M,Babaie F,Gowhari Shabgah A,Azizi G,Hosseini F,Majidi J,Baradaran B

更新日期：2018-08-01 00:00:00

abstract：:Methylxantine derivative, caffeine, is known to prevent the p53-dependent apoptosis pathway via inhibition of ATM (ataxia telangiectasia mutated) kinase, which activates p53 by phosphorylation of the Ser-15 residue. In contrast, it has been reported that caffeine induces p53-mediated apoptosis through Bax protein in n...

journal_title：Journal of cellular physiology

authors： Ito K,Nakazato T,Miyakawa Y,Yamato K,Ikeda Y,Kizaki M

更新日期：2003-08-01 00:00:00

abstract：:Wound healing is a complex but a fine-tuned biological process in which human skin has the ability to regenerate itself following damage. However, in particular conditions such as deep burn or diabetes the process of wound healing is compromised. Despite investigations on the potency of a wide variety of stem cells fo...

journal_title：Journal of cellular physiology

authors： Hassanshahi A,Hassanshahi M,Khabbazi S,Hosseini-Khah Z,Peymanfar Y,Ghalamkari S,Su YW,Xian CJ

更新日期：2019-06-01 00:00:00

abstract：:Increased neovascularization is commonly observed in hemorrhagic plaques and associated with rupture of atherosclerotic lesions. This study aims to investigate whether hemin accumulated at the site of hematoma promotes neovascularization through affecting the growth and function of endothelial progenitor cells (EPCs) ...

journal_title：Journal of cellular physiology

authors： Wang JY,Lee YT,Chang PF,Chau LY

更新日期：2009-06-01 00:00:00

abstract：:The periderm is a flat layer of epithelium created during embryonic development. During palatogenesis, the periderm forms a protective layer against premature adhesion of the oral epithelia, including the palate. However, the periderm must be removed in order for the medial edge epithelia (MEE) to properly adhere and ...

journal_title：Journal of cellular physiology

authors： Hu L,Liu J,Li Z,Ozturk F,Gurumurthy C,Romano RA,Sinha S,Nawshad A

更新日期：2015-06-01 00:00:00