Food Allergy: A Comprehensive Population-Based Cohort Study.


OBJECTIVE:To determine the incidence and temporal trends of food allergies. PATIENTS AND METHODS:We performed a historical cohort study to describe the epidemiology of food allergies among residents of all ages in Olmsted County, Minnesota, during a 10-year period from January 2, 2002, through December 31, 2011, using the Rochester Epidemiology Project database. Overall incidence and trends in biannual incidence rates over time were evaluated. RESULTS:During the 10-year study period, 578 new cases of food allergies were diagnosed. The average annual incidence rate was significantly higher among males compared with females (4.1 [95% CI, 3.6-4.5] vs 3.0 [95% CI, 2.7-3.4]; P<.001; per 10,000 person-years; 3.6 per 10,000 person-years overall). The pediatric incidence rate of food allergy increased from 7.0 (95% CI, 6.2-8.9) to 13.3 (95% CI, 10.9-15.7) per 10,000 person-years between the 2002-2003 and 2006-2007 calendar periods and then stabilized at 12.5 and 12.1 per 10,000 person-years in the last 2 calendar periods. Milk, peanut, and seafood were the most common allergen in infancy, in children between ages 1 and 4 years, and in the adult population, respectively. CONCLUSION:This is one of the first population-based studies to examine the temporal trends of food allergies. The incidence of food allergies increased markedly between 2002 and 2009, with stabilization afterward. Additional longitudinal studies are warranted to assess for epidemiological evidence of changes in food allergy incidence with changing recommendations for allergenic food introduction.


Mayo Clin Proc


Mayo Clinic proceedings


Willits EK,Park MA,Hartz MF,Schleck CD,Weaver AL,Joshi AY




Has Abstract


2018-10-01 00:00:00














  • Epidemiology, treatment, and prevention of community-acquired methicillin-resistant Staphylococcus aureus infections.

    abstract::Since first described In 1961, methicillin-resistant Staphylococcus aureus (MRSA) has become a common nosocomial pathogen. Substantial increases in MRSA infections among nonhospitalized patients are being reported. Methicillin-resistant S. aureus is the most common isolate from skin and soft tissue infections in selec...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Kowalski TJ,Berbari EF,Osmon DR

    更新日期:2005-09-01 00:00:00

  • Ovarian dysgerminoma: a retrospective analysis of results of treatment, sites of treatment failure, and radiosensitivity.

    abstract::Thirty-five patients with a diagnosis of pure ovarian dysgerminoma underwent assessment at our institution between 1950 and 1984. The median age of these patients was 21 years (range, 8 to 41 years). The surgical pathologic stages of the tumors were as follows: stage IA1 in 18 patients, stage IA2 in 2, stage IB1 in 2,...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Buskirk SJ,Schray MF,Podratz KC,Lee RA,Stanhope CR,Gaffey TA,Weber FC,Earle JD,Naessens JM,Malkasian GD

    更新日期:1987-12-01 00:00:00

  • Antibiotic therapy for severe infections in infants and children.

    abstract::Guidelines for the use of antibiotics in infants and children must take into account drug absorption, distribution, metabolism, and excretion. In the developing human being, these factors may differ significantly from those in the adult, and so there are differences in therapeutic efficacy and toxicity. Certain drugs ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Rhodes KH

    更新日期:1977-11-01 00:00:00

  • Thoracic manifestations after esophageal variceal sclerotherapy.

    abstract::Endoscopic esophageal variceal sclerotherapy (EVS) is often used in the treatment of upper gastrointestinal hemorrhage due to esophageal varices. We retrospectively reviewed the Mayo Clinic experience with EVS between 1980 and 1989 to determine the incidence of thoracic manifestations and chest roentgenographic abnorm...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Zeller FA,Cannan CR,Prakash UB

    更新日期:1991-07-01 00:00:00

  • The German Pflegeversicherung (long-term care insurance).

    abstract::The German Pflegeversicherung, introduced in January 1995, has been very successful. It has been well accepted by persons in need and by their relatives and friends, providing benefits for both parties. The insurance is financially sound and has helped to create new workplaces. ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Wahner-Roedler DL,Knuth P,Juchems RH

    更新日期:1999-02-01 00:00:00

  • Percutaneous transcatheter embolization of coronary arteriovenous fistulas.

    abstract::Coronary artery fistulas are infrequently encountered vascular communications that are either congenital or due to cardiac trauma. Most patients with these anomalies are asymptomatic, but late complications can occur and include congestive heart failure, myocardial ischemia, arrhythmias, and endocarditis. Therefore, m...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Harris WO,Andrews JC,Nichols DA,Holmes DR Jr

    更新日期:1996-01-01 00:00:00

  • The necessity for clinical reasoning in the era of evidence-based medicine.

    abstract::Clinical decisions are increasingly driven by evidence-based recommendations of guideline groups, which aim to be based on the highest quality knowledge-randomized clinical trials (RCTs) and meta-analyses. Although RCTs provide the best assessment of the overall value of a therapy, high-quality evidence from RCTs is o...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Sniderman AD,LaChapelle KJ,Rachon NA,Furberg CD

    更新日期:2013-10-01 00:00:00

  • Prognostic value of cardiac troponin T after myocardial infarction: a contemporary community experience.

    abstract:OBJECTIVE:To evaluate the role of cardiac troponin T (cTnT) in predicting death, recurrent ischemic events, and heart failure among community-dwelling persons with first myocardial infarction (MI). PATIENTS AND METHODS:Consecutive Olmsted County, Minnesota, residents with an incident MI between November 6, 2002, and D...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Gerber Y,Jaffe AS,Weston SA,Jiang R,Roger VL

    更新日期:2012-03-01 00:00:00

  • Diagnosis of obesity by primary care physicians and impact on obesity management.

    abstract:OBJECTIVE:To evaluate whether primary care physicians document obesity as a diagnosis and formulate a management plan. PATIENTS AND METHODS:The Mayo Clinic primary care database was used to identify general medical examinations performed from November 1, 2004, to October 31, 2005, in a primary care clinic for obese pa...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Bardia A,Holtan SG,Slezak JM,Thompson WG

    更新日期:2007-08-01 00:00:00

  • A computerized simulator for critical-care training: new technology for medical education.

    abstract::A patient simulator has been developed for training, certification, modeling, and demonstrating problems in the management of critical-care patients. The Critical Care & Hemodynamic Monitoring Training System consists of a personal computer, software, and a replica of a human torso designed to enable students to pract...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Saliterman SS

    更新日期:1990-07-01 00:00:00

  • Quality of life in 650 lung cancer survivors 6 months to 4 years after diagnosis.

    abstract:OBJECTIVE:To present the results of a quality-of-life (QOL) assessment performed with the current version of the Lung Cancer Symptom Scale (LCSS) questionnaire in a large single-institutional data set of 650 patients with lung cancer. PATIENTS AND METHODS:The study group included 650 patients with pathologically confi...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Svobodník A,Yang P,Novotny PJ,Bass E,Garces YI,Jett JR,Bonner JA,Sloan JA

    更新日期:2004-08-01 00:00:00

  • Medical treatment of benign prostatic hyperplasia: 5 alpha-reductase inhibitors and alpha-adrenergic antagonists.

    abstract::Benign prostatic hyperplasia (BPH), a nonmalignant neoplasm of the prostatic epithelial and stromal tissue, occurs commonly in elderly men. The "gold standard" of care for symptomatic BPH has been and remains transurethral resection of the prostate. This operation, however, like any surgical procedure, has associated ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Monda JM,Oesterling JE

    更新日期:1993-07-01 00:00:00

  • Pneumocystis carinii pneumonia in a 3-month-old infant receiving high-dose corticosteroid therapy for airway hemangiomas.

    abstract::Primary infection with Pneumocystis carinii usually occurs early in life, and young infants receiving prolonged treatment with high-dose corticosteroids may be at risk for the development of symptomatic disease. Prophylaxis with trimethoprim-sulfamethoxazole is safe and effective and should be considered for such infa...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Aviles R,Boyce TG,Thompson DM

    更新日期:2004-02-01 00:00:00

  • The early history of giant cell arteritis and polymyalgia rheumatica: first descriptions to 1970.

    abstract::Giant cell arteritis and polymyalgia rheumatica were described separately more than 100 years ago. However, the original reports of both conditions were neglected for many years. After the article by Horton et al on giant cell arteritis in the 1930s and studies published by others in the 1940s, giant cell arteritis be...

    journal_title:Mayo Clinic proceedings

    pub_type: 历史文章,杂志文章


    authors: Hunder GG

    更新日期:2006-08-01 00:00:00

  • Safety, diagnostic yield, and therapeutic implications of flexible bronchoscopy in patients with febrile neutropenia and pulmonary infiltrates.

    abstract:OBJECTIVE:To evaluate the safety, diagnostic yield, and therapeutic implications of flexible bronchoscopy with bronchoalveolar lavage (BAL) and transbronchial biopsy in patients with febrile neutropenia and pulmonary infiltrates. PATIENTS AND METHODS:We retrospectively reviewed the medical records of all patients with...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Peikert T,Rana S,Edell ES

    更新日期:2005-11-01 00:00:00

  • Albuminocytologic Dissociation in Posterior Reversible Encephalopathy Syndrome.

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    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Datar S,Singh TD,Fugate JE,Mandrekar J,Rabinstein AA,Hocker S

    更新日期:2015-10-01 00:00:00

  • Factors affecting survival and occurrence of stroke in patients with transient ischemic attacks.

    abstract:OBJECTIVE:To assess the predictive value of a series of demographic and clinical variables for stroke and survival in a population after a first transient ischemic attack (TIA). DESIGN:Cox proportional hazards regression analysis was used to determine the association of various demographic and clinical factors with su...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Evans BA,Sicks JD,Whisnant JP

    更新日期:1994-05-01 00:00:00

  • Cessation of unsuccessful pediatric resuscitation--how long is too long?

    abstract::Emergency teams asked to provide cardiopulmonary resuscitation for pediatric patients often consist of nurses and physicians from various pediatric and nonpediatric specialties. Team members should agree on the timing of termination of unsuccessful resuscitative efforts; however, no firm guidelines about such timing h...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: O'Marcaigh AS,Koenig WJ,Rosekrans JA,Berseth CL

    更新日期:1993-04-01 00:00:00

  • Acute pancreatitis in the postpartum period: a population-based case-control study.

    abstract:OBJECTIVE:To determine relationships among pregnancy (during and postpartum), acute pancreatitis, and gallstones. PATIENTS AND METHODS:In this retrospective population-based case-control study, we identified all 12- to 50-year-old Rochester, Minn, females diagnosed between 1976 and 1991 as having acute pancreatitis (c...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Maringhini A,Lankisch MR,Zinsmeister AR,Melton LJ 3rd,DiMagno EP

    更新日期:2000-04-01 00:00:00

  • Adjuvant Therapy in High-Risk Renal Cell Cancer: A Systematic Review and Meta-analysis.

    abstract:OBJECTIVE:To perform a systematic review and meta-analysis of randomized controlled trials (RCTs) evaluating risk-benefit for adjuvant postoperative treatments in high-risk renal cell carcinoma by assessing reported disease-free survival (DFS), overall survival (OS), toxicity, and quality of life. METHODS:A literature...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,meta分析


    authors: Riaz IB,Faridi W,Husnain M,Malik SU,Sipra QUAR,Gondal FR,Xie H,Yadav S,Kohli M

    更新日期:2019-08-01 00:00:00

  • An unusual compressive syndrome of the cauda equina.

    abstract::An unusual case of a capillary hemangioma of the filum terminale is presented. The successful removal returned the patient to an asymptomatic state. ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Freeman RE,Onofrio BM,Layton DD Jr

    更新日期:1975-03-01 00:00:00

  • Fluoroscopically Guided vs Landmark-Guided Sacroiliac Joint Injections: A Randomized Controlled Study.

    abstract:OBJECTIVES:To determine the prevalence of intra- and extra-articular sacroiliac joint (SIJ) pain, which injection is more beneficial, and whether fluoroscopy improves outcomes. PATIENTS AND METHODS:This patient- and evaluator-blinded comparative effectiveness study randomized 125 participants with SIJ pain from April ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,随机对照试验


    authors: Cohen SP,Bicket MC,Kurihara C,Griffith SR,Fowler IM,Jacobs MB,Liu R,Anderson White M,Verdun AJ,Hari SB,Fisher RL,Pasquina PF,Vorobeychik Y

    更新日期:2019-04-01 00:00:00

  • Attitude and disposition: do they make a difference in cancer survival?

    abstract::Psychosocial and spiritual factors influence a broad spectrum of medical and surgical disorders. The adverse effects of stress have been most clearly documented in cardiovascular disease. In cancer, unresolved questions include the following: Do emotional factors have a causal role in either initiating or promoting a ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Creagan ET

    更新日期:1997-02-01 00:00:00

  • Primarily resected meningiomas: outcome and prognostic factors in 581 Mayo Clinic patients, 1978 through 1988.

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    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Stafford SL,Perry A,Suman VJ,Meyer FB,Scheithauer BW,Lohse CM,Shaw EG

    更新日期:1998-10-01 00:00:00

  • Monoclonal gammopathy of undetermined significance: predictors of malignant transformation and recognition of an evolving type characterized by a progressive increase in M protein size.

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    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Rosiñol L,Cibeira MT,Montoto S,Rozman M,Esteve J,Filella X,Bladé J

    更新日期:2007-04-01 00:00:00

  • Anatomic correction of dextrotransposition of the great arteries in a 36-year-old patient.

    abstract::During the 1960s, the Mustard or Senning operation was the conventional palliative therapy for patients with transposition of the great arteries. Many of these patients are now adults, and the durability of the morphologic right ventricle to function as the systemic ventricle is being questioned. Surgical options for ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Cetta F,Bonilla JJ,Lichtenberg RC,Stasior C,Troman JE,Deleon SY

    更新日期:1997-03-01 00:00:00

  • Transurethral microwave thermotherapy for prostatism: early Mayo Foundation experience.

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    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,多中心研究


    authors: Blute ML,Tomera KM,Hellerstein DK,Atkinson EJ,Patterson DE,Segura JW

    更新日期:1992-05-01 00:00:00

  • Analysis of trochlear nerve palsies. Diagnosis, etiology, and treatment.

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    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Younge BR,Sutula F

    更新日期:1977-01-01 00:00:00

  • Communication and the humanities: the nature of the nexus.

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    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Little JM

    更新日期:1993-09-01 00:00:00

  • Post-September 11, 2001, Incidence of Systemic Autoimmune Diseases in World Trade Center-Exposed Firefighters and Emergency Medical Service Workers.

    abstract:OBJECTIVE:To estimate the incidence of selected systemic autoimmune diseases (SAIDs) in approximately 14,000 male rescue/recovery workers enrolled in the Fire Department of the City of New York (FDNY) World Trade Center (WTC) Health Program and to compare FDNY incidence to rates from demographically similar men in the ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Webber MP,Moir W,Crowson CS,Cohen HW,Zeig-Owens R,Hall CB,Berman J,Qayyum B,Jaber N,Matteson EL,Liu Y,Kelly K,Prezant DJ

    更新日期:2016-01-01 00:00:00