Food Allergy: A Comprehensive Population-Based Cohort Study.


OBJECTIVE:To determine the incidence and temporal trends of food allergies. PATIENTS AND METHODS:We performed a historical cohort study to describe the epidemiology of food allergies among residents of all ages in Olmsted County, Minnesota, during a 10-year period from January 2, 2002, through December 31, 2011, using the Rochester Epidemiology Project database. Overall incidence and trends in biannual incidence rates over time were evaluated. RESULTS:During the 10-year study period, 578 new cases of food allergies were diagnosed. The average annual incidence rate was significantly higher among males compared with females (4.1 [95% CI, 3.6-4.5] vs 3.0 [95% CI, 2.7-3.4]; P<.001; per 10,000 person-years; 3.6 per 10,000 person-years overall). The pediatric incidence rate of food allergy increased from 7.0 (95% CI, 6.2-8.9) to 13.3 (95% CI, 10.9-15.7) per 10,000 person-years between the 2002-2003 and 2006-2007 calendar periods and then stabilized at 12.5 and 12.1 per 10,000 person-years in the last 2 calendar periods. Milk, peanut, and seafood were the most common allergen in infancy, in children between ages 1 and 4 years, and in the adult population, respectively. CONCLUSION:This is one of the first population-based studies to examine the temporal trends of food allergies. The incidence of food allergies increased markedly between 2002 and 2009, with stabilization afterward. Additional longitudinal studies are warranted to assess for epidemiological evidence of changes in food allergy incidence with changing recommendations for allergenic food introduction.


Mayo Clin Proc


Mayo Clinic proceedings


Willits EK,Park MA,Hartz MF,Schleck CD,Weaver AL,Joshi AY




Has Abstract


2018-10-01 00:00:00














  • Associations of preexisting depression and anxiety with hospitalization in patients with cardiovascular disease.

    abstract:OBJECTIVE:To determine the risk of hospitalization and death in relation to preexisting depression and anxiety among patients with cardiovascular disease (CVD). PATIENTS AND METHODS:The cohort consisted of 799 Olmsted County, MN, residents diagnosed with CVD (myocardial infarction or heart failure) from January 1, 197...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Chamberlain AM,Vickers KS,Colligan RC,Weston SA,Rummans TA,Roger VL

    更新日期:2011-11-01 00:00:00

  • Generalized convulsive status epilepticus.

    abstract::Generalized convulsive status epilepticus (GCSE) is a medical emergency that may be associated with severe neuronal injury. The mortality attributable to GCSE ranges from 3 to 35%. The disorder occurs most frequently in the young and the old extremes of the population. GCSE commonly occurs in patients with no history ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Cascino GD

    更新日期:1996-08-01 00:00:00

  • Wegener's granulomatosis associated with vasculitis of the temporal artery: report of five cases.

    abstract::Between January 1973 and October 1991 at the Mayo Clinic, 5 of 345 patients with Wegener's granulomatosis initially had features suggestive of giant cell arteritis and subsequently were found to have biopsy-proven vasculitis of the temporal artery. All five patients were older than 60 years of age and had jaw claudica...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Nishino H,DeRemee RA,Rubino FA,Parisi JE

    更新日期:1993-02-01 00:00:00

  • Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management.

    abstract::Drugs that target G protein-coupled receptors (GPCRs) represent the primary treatment strategy for patients with acute and chronic pain; however, there is substantial individual variability in both the efficacy and adverse effects associated with these drugs. Variability in drug responses is due, in part, to individua...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Oladosu FA,Maixner W,Nackley AG

    更新日期:2015-08-01 00:00:00

  • Fatal disseminated intravascular coagulation after peritoneovenous shunt for intractable ascites.

    abstract::Peritoneovenous shunt for intractable ascites was complicated by disseminated intravascular coagulation, which resulted in the death of the patient. Attention is called to this potentially serious complication. The cause of disseminated intravascular coagulation occurring after peritoneovenous shunt is uncertain. Pati...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Matseshe JW,Beart RW,Bartholomew LG,Baldus WP

    更新日期:1978-08-01 00:00:00

  • Ondansetron-induced multifocal encephalopathy.

    abstract::We treated a patient who developed transient multifocal encephalopathy with extrapyramidal symptoms (oromandibular dystonia, oculogyric crisis, and limb dystonia) in temporal proximity to ondansetron administration on emergence from general anesthesia. No other medications known to cause extrapyramidal reactions were ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Ritter MJ,Goodman BP,Sprung J,Wijdicks EF

    更新日期:2003-09-01 00:00:00

  • Incidence and Predictors of Infective Endocarditis in Mitral Valve Prolapse: A Population-Based Study.

    abstract:OBJECTIVE:To determine the incidence and predictors of infective endocarditis (IE) in a population-based cohort of patients with mitral valve prolapse (MVP). PATIENTS AND METHODS:We identified all adult Olmsted County residents with MVP diagnosed by echocardiography from January 1989 to December 1998 and cross-matched...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Katan O,Michelena HI,Avierinos JF,Mahoney DW,DeSimone DC,Baddour LM,Suri RM,Enriquez-Sarano M

    更新日期:2016-03-01 00:00:00

  • Horseshoe kidney associated with surgery of the abdominal aorta.

    abstract::Of 53 patients with horseshoe kidney (9 in the present series), 45 underwent operation for an abdominal aortic aneurysm: 40 electively and 5 on an emergency basis. The remaining eight patients underwent revascularization for arteriosclerosis obliterans. Of the 53 patients, 35 (66%) had renal artery anomalies. The anom...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Sidell PM,Pairolero PC,Payne WS,Bernatz PE,Spittel JA Jr

    更新日期:1979-02-01 00:00:00

  • Image enhancement by noncontrast harmonic echocardiography. Part II. Quantitative assessment with use of contrast-to-speckle ratio.

    abstract:OBJECTIVE:To ascertain whether "harmonic imaging"--use of ultrasound signals with the frequency twice that of the transmitted signal for ultrasound image generation--can improve image contrast while reducing noise. METHODS:Technically difficult echocardiograms (nonvisualization of 2 or more endocardial segments in a 1...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Belohlavek M,Tanabe K,Mulvagh SL,Foley DA,Greenleaf JF,Seward JB

    更新日期:1998-11-01 00:00:00

  • Treating tobacco dependence in light of the 2008 US Department of Health and Human Services clinical practice guideline.

    abstract::Cigarette smoking is the most important preventable cause of morbidity, mortality, and excess health care costs in the United States. From 2000 through 2004, cigarette smoking caused an estimated annual average of 443,595 deaths and cost $193 billion per year in smoking-attributable productivity losses and smoking-rel...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Hays JT,Ebbert JO,Sood A

    更新日期:2009-08-01 00:00:00

  • Age and history of cardiac disease as risk factors for cardiac complications after peripheral vascular surgery in diabetic patients.

    abstract:OBJECTIVE:To examine the relationship of age and clinical factors to postoperative cardiovascular events in a cohort of diabetic patients undergoing peripheral vascular surgery. PATIENTS AND METHODS:In this cohort study, 316 diabetic patients were followed up prospectively after femoral-to-distal artery bypass surgery...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Zarich SW,Pierce ET,Nesto RW,Mittleman MA,Bode RH,Kowalchuk G,Cohen MC

    更新日期:2001-01-01 00:00:00

  • Progress in the diagnosis and management of aortic dissection.

    abstract::A 36-year-old man sought medical attention because of pressure in his head and distention of the veins in his neck. Physical examination disclosed a murmur of aortic insufficiency, and a chest roentgenogram showed a dilated ascending aorta. Two-dimensional echocardiography and angiography demonstrated a large intimal ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Cooke JP,Safford RE

    更新日期:1986-02-01 00:00:00

  • Laparoscopic placement of ventriculoperitoneal shunts: preliminary report.

    abstract::We used a laparoscopic technique for the percutaneous placement of the peritoneal end of cerebrospinal fluid shunts in adult patients with obstructive or normal-pressure hydrocephalus. Concurrent with the initial cranial part of the procedure, pneumoperitoneum is established in a routine fashion, and a video-laparosco...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Schievink WI,Wharen RE Jr,Reimer R,Pettit PD,Seiler JC,Shine TS

    更新日期:1993-11-01 00:00:00

  • Clinical value of the bile acid breath test. Evaluation of the Mayo Clinic experience.

    abstract::The Mayo Clinic experience with more than 200 bile acid breath tests was analyzed retrospectively to assess its clinical value. In patients with suspected bacterial overgrowth, the result of the bile acid breath test was compared with that of culture of aspirates of small bowel, and the test was found to have a sensit...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Lauterburg BH,Newcomer AD,Hofmann AF

    更新日期:1978-04-01 00:00:00

  • Omega-3 fatty acids for cardioprotection.

    abstract::The most compelling evidence for the cardiovascular benefit provided by omega-3 fatty acids comes from 3 large controlled trials of 32,000 participants randomized to receive omega-3 fatty acid supplements containing docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) or to act as controls. These trials showed r...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Lee JH,O'Keefe JH,Lavie CJ,Marchioli R,Harris WS

    更新日期:2008-03-01 00:00:00

  • Increasing Incidence of Melanoma in the Elderly: An Epidemiological Study in Olmsted County, Minnesota.

    abstract:OBJECTIVE:To estimate the age- and sex-adjusted incidence of melanoma in adults 61 years or older in Olmsted County, Minnesota, from 1970 through 2009. PATIENTS AND METHODS:Using Rochester Epidemiology Project resources, 397 patients were identified who were 61 years or older and who received a first lifetime diagnosi...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Olazagasti Lourido JM,Ma JE,Lohse CM,Brewer JD

    更新日期:2016-11-01 00:00:00

  • Complication rates between local and referral patients undergoing vaginal hysterectomy at an academic medical center.

    abstract:OBJECTIVE:To explore the influence of referral bias on complication rates after vaginal hysterectomy. PATIENTS AND METHODS:Community-based (local) and referral patients had benign indications and underwent vaginal hysterectomy from January 1, 2004, through December 31, 2005. We retrospectively evaluated patient charac...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Heisler CA,Melton LJ 3rd,Weaver AL,Gebhart JB

    更新日期:2010-02-01 00:00:00

  • Nutritional assessment of orthopedic patients.

    abstract::Eighty-two consecutive orthopedic patients were assessed nutritionally at the time of hospital admission and then at 10-day intervals until hospital dismissal. Forty-eight percent of the patients had one or more abnormal findings suggestive of protein-calorie malnutrition. In spite of this prevalence of abnormal findi...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Dreblow DM,Anderson CF,Moxness K

    更新日期:1981-01-01 00:00:00

  • Chronic Constipation.

    abstract::Constipation is a common symptom that may be primary (idiopathic or functional) or associated with a number of disorders or medications. Although most constipation is self-managed by patients, 22% seek health care, mostly to primary care physicians (>50%) and gastroenterologists (14%), resulting in large expenditures ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Bharucha AE,Wald A

    更新日期:2019-11-01 00:00:00

  • Telemedicine consultations in congenital heart disease: assessment of advanced technical capabilities.

    abstract:OBJECTIVE:To assess the value of adding remote pointer and dynamic display capabilities to a telemedicine system designed to provide consultative services for patients with congenital heart disease. MATERIAL AND METHODS:Independent observations by the referring physician and the consulting physician provided the data ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Julsrud PR,Breen JF,Jedeikin R,Peoples W,Wondrow MA,Bailey KR

    更新日期:1999-08-01 00:00:00

  • Preoperative laboratory screening in healthy Mayo patients: cost-effective elimination of tests and unchanged outcomes.

    abstract::We reviewed the results of preoperative screening laboratory tests in asymptomatic healthy patients who underwent elective surgical procedures at our institution in 1988. Substantially abnormal results were found in 160 of 3,782 patients. All such abnormalities involved five tests: aspartate aminotransferase, glucose,...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Narr BJ,Hansen TR,Warner MA

    更新日期:1991-02-01 00:00:00

  • Clinician's guide to hepatitis C.

    abstract::Hepatitis C virus infection is common, often silent, and almost always chronic and can lead to cirrhosis and hepatocellular cancer. Deaths related to chronic hepatitis C are expected to increase dramatically in the future. Many cases of infection are asymptomatic and are undiagnosed because of a lack of recognition by...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Gross JB Jr

    更新日期:1998-04-01 00:00:00

  • Myectomy for essential blepharospasm.

    abstract::Essential blepharospasm is a progressive, bilateral, involuntary facial spasm. In this study, we conducted a prospective analysis of myectomy for the treatment of this condition in 21 patients. The procedure consisted of extirpation of the muscles that close the eyelids (protractors), which include the pretarsal, pres...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Jones TW Jr,Waller RR,Samples JR

    更新日期:1985-10-01 00:00:00

  • Childhood Attention-Deficit/Hyperactivity Disorder, Sex, and Obesity: A Longitudinal Population-Based Study.

    abstract:OBJECTIVE:To assess obesity rates during childhood and young adulthood in patients with attention-deficit/hyperactivity disorder (ADHD) and age- and sex-matched controls derived from a population-based birth cohort because cross-sectional studies suggest an association between ADHD and obesity. PATIENTS AND METHODS:St...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Aguirre Castaneda RL,Kumar S,Voigt RG,Leibson CL,Barbaresi WJ,Weaver AL,Killian JM,Katusic SK

    更新日期:2016-03-01 00:00:00

  • Outcomes of primary and secondary treatment of pericardial effusion in patients with malignancy.

    abstract:OBJECTIVE:To evaluate the treatment strategies for primary and secondary management of malignancy-related pericardial effusions. PATIENTS AND METHODS:Retrospective review of Mayo Clinic Rochester charts and external records of patients with pericardial effusion associated with malignant disease who required treatment ...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Tsang TS,Seward JB,Barnes ME,Bailey KR,Sinak LJ,Urban LH,Hayes SN

    更新日期:2000-03-01 00:00:00

  • Cerebrospinal fluid physiology and the management of increased intracranial pressure.

    abstract::Increased intracranial pressure can result in irreversible injury to the central nervous system. Among the many functions of the cerebrospinal fluid, it provides protection against acute changes in venous and arterial blood pressure or impact pressure. Nevertheless, trauma, tumors, infections, neurosurgical procedures...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Lyons MK,Meyer FB

    更新日期:1990-05-01 00:00:00

  • Progress in pediatric solid tumors.

    abstract::Since 1980, impressive progress in the treatment of solid tumors has altered the practice of pediatric surgical oncology. Because these advances have been balanced by both liberal and conservative viewpoints, an accurate reassessment of traditional approaches has been possible. Noteworthy alterations in chemotherapy, ...

    journal_title:Mayo Clinic proceedings

    pub_type: 临床试验,杂志文章


    authors: Kaufman BH

    更新日期:1986-04-01 00:00:00

  • Adult-Onset Hypogonadism.

    abstract::In August 2015, an expert colloquium commissioned by the Sexual Medicine Society of North America (SMSNA) convened in Washington, DC, to discuss the common clinical scenario of men who present with low testosterone (T) and associated signs and symptoms accompanied by low or normal gonadotropin levels. This syndrome is...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Khera M,Broderick GA,Carson CC 3rd,Dobs AS,Faraday MM,Goldstein I,Hakim LS,Hellstrom WJ,Kacker R,Köhler TS,Mills JN,Miner M,Sadeghi-Nejad H,Seftel AD,Sharlip ID,Winters SJ,Burnett AL

    更新日期:2016-07-01 00:00:00

  • Left ventricular outflow tract obstruction related to a valve prosthesis: case caused by a low-profile mitral prosthesis.

    abstract::Mechanical and bioprosthetic mitral prostheses may have many potential complications. In patients with isolated mitral stenosis and a small left ventricular cavity, low-profile prostheses are recommended to avoid myocardial impingement that can result from a high-profile valve and lead to possible left ventricular inf...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章


    authors: Currie PJ,Seward JB,Lam JB,Gersh BJ,Pluth JR

    更新日期:1985-03-01 00:00:00

  • Gycemic control, mealtime glucose excursions, and diabetic complications in type 2 diabetes mellitus.

    abstract::Type 2 diabetes mellitus is a heterogeneous disorder characterized by 2 pathogenic defects, impaired insulin secretion and insulin resistance. The resultant hyperglycemia causes microvascular and macrovascular complications that increase morbidity and mortality in patients with diabetes mellitus. Optimum glycemic cont...

    journal_title:Mayo Clinic proceedings

    pub_type: 杂志文章,评审


    authors: Palumbo PJ

    更新日期:2001-06-01 00:00:00