Correlation between retinal vein occlusion and cancer - a nationwide Danish cohort study.


PURPOSE:To explore the association between retinal vein occlusion (RVO) and incident cancer. METHODS:All Danish citizens with a first-time diagnosis of RVO and no previous diagnosis of cancer in the period from 1 January 2004 to 31 December 2014 were included. Five likewise cancer-free, age- and gender-matched controls were included in a control cohort. All were followed up for 5 years or until either first diagnosis of cancer or death. Proportional hazards models with adjustment for age, gender, year of diagnosis and covariates and death as competing risk were used to estimate the risk of being diagnosed with cancer. RESULTS:There were 7963 RVO patients without cancer at the time of diagnosis, and all could be matched to likewise cancer-free controls. Half of RVO patients were male, and the median age at RVO diagnosis was 70 years (61-79). The control cohort was similar in terms of gender and age. The risk of cancer within 1 year was 1.8 among RVO patients and 1.5 among controls. The crude risk of cancer was 1.22 (1.11;1.34) and upon full adjustment 1.15 (1.05;1.27). No time dependency was detected, and the types of cancer developed in RVO patients and controls were similar. CONCLUSION:Retinal vein occlusion (RVO) diagnosis is associated with an increased risk of being diagnosed with cancer. This risk is likely to reflect shared risk factors rather than a causal association.


Acta Ophthalmol


Acta ophthalmologica


Toft-Petersen AP,Muttuvelu DV,Heegaard S,Torp-Pedersen C




Has Abstract


2018-12-01 00:00:00












  • Aflibercept vs. Ranibizumab: cost-effectiveness of treatment for wet age-related macular degeneration in Sweden.

    abstract:PURPOSE:Monthly dosing with ranibizumab (RBZ) is needed to achieve maximal visual gains in patients with neovascular ('wet') age-related macular degeneration (wAMD). In Sweden, dosing is performed as needed (RBZ PRN), resulting in suboptimal efficacy. Intravitreal aflibercept (IVT-AFL) every 2 months after three initia...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Panchmatia HR,Clements KM,Hulbert E,Eriksson M,Wittrup-Jensen K,Nilsson J,Weinstein MC

    更新日期:2016-08-01 00:00:00

  • Validation and comparison of the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) and the Visual Function Index-14 (VF-14) in patients with cataracts: a multicentre study.

    abstract:PURPOSE:The present study aimed to investigate and compare the psychometric properties of the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) and the Visual Function Index-14 (VF-14) in a large sample of patients with cataracts. METHODS:A total of 1052 patients with bilateral age-related catara...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Wan Y,Zhao L,Huang C,Xu Y,Sun M,Yang Y,An L,Lv S,Yu Y,Chen D,Zhou P,Wang Y,Zhang M,Jiang A,Chen Z,Li X

    更新日期:2020-09-17 00:00:00

  • Corneal surface reconstruction using adult mesenchymal stem cells in experimental limbal stem cell deficiency in rabbits.

    abstract:PURPOSE:To investigate the ability of mesenchymal stem cells (MSC) to transdifferentiate to corneal epithelial cells in experimental limbal stem cell deficiency in rabbits. METHODS:Total limbal stem cell deficiency was produced in 21 right eyes of 21 New Zealand rabbits; 6 eyes served as controls (group 1, G1). After ...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Reinshagen H,Auw-Haedrich C,Sorg RV,Boehringer D,Eberwein P,Schwartzkopff J,Sundmacher R,Reinhard T

    更新日期:2011-12-01 00:00:00

  • Disseminated tumour cells in bone marrow of patients with uveal melanoma.

    abstract:PURPOSE:Approximately 50% of patients with uveal melanomas develop metastases. Thus, it is important to improve our understanding of how melanoma metastases develop. METHODS:As part of a uveal melanoma micrometastasis study, we compared the detection rates of immunomagnetically selected (IMS) tumour cells in bone marr...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Eide N,Hoifødt HK,Nesland JM,Faye RS,Qvale GA,Faber RT,Jebsen P,Kvalheim G,Fodstad Ø

    更新日期:2013-06-01 00:00:00

  • Corneal biomechanical characteristics measured by the CorVis Scheimpflug technology in eyes with primary open-angle glaucoma and normal eyes.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Tian L,Wang D,Wu Y,Meng X,Chen B,Ge M,Huang Y

    更新日期:2016-08-01 00:00:00

  • Intravitreal triamcinolone as adjunctive treatment to laser panretinal photocoagulation for concomitant proliferative diabetic retinopathy and clinically significant macular oedema.

    abstract:PURPOSE:To evaluate the effect of intravitreal injections of triamcinolone acetonide (IVTA) combined with panretinal photocoagulation (PRP) on visual acuity (VA) and foveal thickness in patients with concomitant high-risk proliferative diabetic retinopathy (PDR) and clinically significant macular oedema (CSMO). METHOD...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Margolis R,Singh RP,Bhatnagar P,Kaiser PK

    更新日期:2008-02-01 00:00:00

  • Intraocular lens dislocation in pseudoexfoliation: a systematic review and meta-analysis.

    abstract:PURPOSE:To evaluate the impact of pseudoexfoliation syndrome on intraocular lens (IOL) dislocation after phacoemulsification cataract surgery and explore possible associations related to surgical technique. METHODS:We systematically searched the MEDLINE, Embase, Web of Science, Cochrane, and Lilacs databases and grey ...

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    pub_type: 杂志文章,meta分析,评审


    authors: Vazquez-Ferreiro P,Carrera-Hueso FJ,Fikri-Benbrahim N,Barreiro-Rodriguez L,Diaz-Rey M,Ramón Barrios MA

    更新日期:2017-05-01 00:00:00

  • Global burden and gender disparity of vision loss associated with diabetes retinopathy.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Xu Y,Wang A,Lin X,Xu J,Shan Y,Pan X,Ye J,Shan PF

    更新日期:2020-10-29 00:00:00

  • Internal cyclopexy for complicated traumatic cyclodialysis cleft.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Wang C,Peng XY,You QS,Liu Y,Pang XQ,Zheng PF,Jonas JB

    更新日期:2017-09-01 00:00:00

  • Keratoconus in 18 pairs of twins.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Tuft SJ,Hassan H,George S,Frazer DG,Willoughby CE,Liskova P

    更新日期:2012-09-01 00:00:00

  • Segregation analysis suggests that keratoconus is a complex non-mendelian disease.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Kriszt A,Losonczy G,Berta A,Vereb G,Takács L

    更新日期:2014-11-01 00:00:00

  • Treatment patterns, visual acuity and quality-of-life outcomes of the WAVE study - a noninterventional study of ranibizumab treatment for neovascular age-related macular degeneration in Germany.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,多中心研究


    authors: Finger RP,Wiedemann P,Blumhagen F,Pohl K,Holz FG

    更新日期:2013-09-01 00:00:00

  • Effect of glaucoma drainage implant surgery on corneal topography: a prospective study.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Koivusalo R,Välimäki J

    更新日期:2020-05-01 00:00:00

  • Impaired cerebrospinal fluid dynamics along the entire optic nerve in normal-tension glaucoma.

    abstract:PURPOSE:To investigate the cerebrospinal fluid (CSF) dynamics along the entire optic nerve (ON) in patients with normal-tension glaucoma (NTG). METHODS:Retrospective analysis of computed tomographic (CT) cisternographies in Caucasian patients with NTG. Fifty-six patients (99 of 112 eyes) fulfilled the diagnostic crite...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Pircher A,Montali M,Wostyn P,Pircher J,Berberat J,Remonda L,Killer HE

    更新日期:2018-08-01 00:00:00

  • Quality assessment of cataract surgery in Denmark - risk of retinal detachment and postoperative endophthalmitis.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Bjerrum SS

    更新日期:2015-03-01 00:00:00

  • Risk factors for the hypertensive phase after implantation of a glaucoma drainage device.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Jung KI,Park CK

    更新日期:2016-08-01 00:00:00

  • C-Reactive protein and progression of vision loss in retinitis pigmentosa.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Murakami Y,Ikeda Y,Nakatake S,Fujiwara K,Tachibana T,Yoshida N,Notomi S,Hisatomi T,Yoshida S,Ishibashi T,Sonoda KH

    更新日期:2018-03-01 00:00:00

  • Influences of cyclopentolate hydrochloride on anterior segment parameters with Pentacam in children.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Palamar M,Egrilmez S,Uretmen O,Yagci A,Kose S

    更新日期:2011-08-01 00:00:00

  • Factors affecting ocular pulse amplitude in eyes with open angle glaucoma and glaucoma-suspect eyes.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Choi J,Lee J,Park SB,Lee KS,Sung KR,Kook MS

    更新日期:2012-09-01 00:00:00

  • Ocular blood flow in glaucoma - the Leuven Eye Study.

    abstract:PURPOSE:Elevated intra-ocular pressure (IOP) has been identified as a major risk factor for glaucoma. Additionally, extensive literature depicts a vascular dysfunction to exist in these patients. However, a large ocular blood flow-oriented trial to integrate these findings in the clinical setting is lacking. This study...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


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    更新日期:2016-09-01 00:00:00

  • Intravitreal pegaptanib sodium (Macugen) for diabetic macular oedema.

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    pub_type: 杂志文章


    authors: Querques G,Bux AV,Martinelli D,Iaculli C,Noci ND

    更新日期:2009-09-01 00:00:00

  • Variability in photocoagulation treatment of diabetic macular oedema.

    abstract:PURPOSE:To establish whether differences in the assessment of diabetic macular oedema (DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead to variability in the photocoagulation treatment of DME. METHODS:The differences in the assessment of DME with either OCT or stereoscopic biomicr...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: van Dijk HW,Verbraak FD,Kok PH,Oberstein SY,Schlingemann RO,Russell SR,Abràmoff MD

    更新日期:2013-12-01 00:00:00

  • A distinct retinal pigment epithelial cell autofluorescence pattern in choroideremia predicts early involvement of overlying photoreceptors.

    abstract:PURPOSE:Choroideremia is an X-linked retinal disease characterized by early retinal pigment epithelium (RPE) loss and subsequent retinal degeneration. The RPE adopts either a smooth or mottled appearance on fundus autofluorescence (FAF). It is not known how RPE changes predict the health of the overlying ellipsoid zone...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Stevanovic M,Cehajic Kapetanovic J,Jolly JK,MacLaren RE

    更新日期:2020-05-01 00:00:00

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Sundling V,Platou CG,Jansson RW,Bertelsen G,Wøllo E,Gulbrandsen P

    更新日期:2012-05-01 00:00:00

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Bonnin P,Pournaras JA,Lazrak Z,Cohen SY,Legargasson JF,Gaudric A,Levy BI,Massin P

    更新日期:2010-09-01 00:00:00

  • Multicenter clinical trial of high-intensity focused ultrasound treatment in glaucoma patients without previous filtering surgery.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Aptel F,Denis P,Rouland JF,Renard JP,Bron A

    更新日期:2016-08-01 00:00:00

  • The influence of background diabetic retinopathy in the second eye on rates of progression of diabetic retinopathy between 2005 and 2010.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Scanlon PH,Stratton IM,Histed M,Chave SJ,Aldington SJ

    更新日期:2013-08-01 00:00:00

  • Evaluation of adding item-response theory analysis for evaluation of the European Board of Ophthalmology Diploma examination.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Mathysen DG,Aclimandos W,Roelant E,Wouters K,Creuzot-Garcher C,Ringens PJ,Hawlina M,Tassignon MJ

    更新日期:2013-11-01 00:00:00

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Majander A,Kivelä TT,Krootila K

    更新日期:2016-09-01 00:00:00

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,多中心研究,随机对照试验


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    更新日期:2018-06-01 00:00:00