Correlation between retinal vein occlusion and cancer - a nationwide Danish cohort study.


PURPOSE:To explore the association between retinal vein occlusion (RVO) and incident cancer. METHODS:All Danish citizens with a first-time diagnosis of RVO and no previous diagnosis of cancer in the period from 1 January 2004 to 31 December 2014 were included. Five likewise cancer-free, age- and gender-matched controls were included in a control cohort. All were followed up for 5 years or until either first diagnosis of cancer or death. Proportional hazards models with adjustment for age, gender, year of diagnosis and covariates and death as competing risk were used to estimate the risk of being diagnosed with cancer. RESULTS:There were 7963 RVO patients without cancer at the time of diagnosis, and all could be matched to likewise cancer-free controls. Half of RVO patients were male, and the median age at RVO diagnosis was 70 years (61-79). The control cohort was similar in terms of gender and age. The risk of cancer within 1 year was 1.8 among RVO patients and 1.5 among controls. The crude risk of cancer was 1.22 (1.11;1.34) and upon full adjustment 1.15 (1.05;1.27). No time dependency was detected, and the types of cancer developed in RVO patients and controls were similar. CONCLUSION:Retinal vein occlusion (RVO) diagnosis is associated with an increased risk of being diagnosed with cancer. This risk is likely to reflect shared risk factors rather than a causal association.


Acta Ophthalmol


Acta ophthalmologica


Toft-Petersen AP,Muttuvelu DV,Heegaard S,Torp-Pedersen C




Has Abstract


2018-12-01 00:00:00












  • Actinomycotic canaliculitis: resolution following surgery and short topical antibiotic treatment.

    abstract:PURPOSE:This study aimed to study the incidence and clinical characteristics of patients diagnosed with actinomycotic canaliculitis in Iceland. METHODS:We present a nationwide, retrospective case series for which cases were identified by searches of hospital diagnostic registries and pathology databases. Case historie...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Baldursdóttir E,Sigurdsson H,Jónasson L,Gottfredsson M

    更新日期:2010-05-01 00:00:00

  • Initial observation or treatment for diabetic macular oedema with good visual acuity: two-year outcomes comparison in routine clinical practice: data from the Fight Retinal Blindness! Registry.

    abstract:PURPOSE:To compare visual acuity (VA) change at 24 months in eyes with clinically significant DME (CSDME) and good VA initially treated versus initially observed in routine clinical practice. METHODS:Retrospective analysis of treatment-naïve eyes with CSDME and good VA (baseline VA ≥ 79 letters), with at least 24 mont...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Gabrielle PH,Nguyen V,Bhandari S,Mehta H,Viola F,Arnold J,Fraser-Bell S,Barthelmes D,Creuzot-Garcher C,Gillies M

    更新日期:2020-11-16 00:00:00

  • Influences of cyclopentolate hydrochloride on anterior segment parameters with Pentacam in children.

    abstract:PURPOSE:To investigate the effects of cyclopentolate hydrochloride 1% on the main numerical parameters of anterior segment with Pentacam rotating Scheimpflug camera in children. SETTING:Ege University Faculty of Medicine, Department of Ophthalmology. METHODS:Pentacam measurements of 50 (23 boys and 27 girls) children...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Palamar M,Egrilmez S,Uretmen O,Yagci A,Kose S

    更新日期:2011-08-01 00:00:00

  • Comparison of macular pigment and serum lutein concentration changes between free lutein and lutein esters supplements in Japanese subjects.

    abstract:PURPOSE:To compare changes in macular pigment optical density (MPOD) and serum lutein concentration between free lutein and lutein esters supplements in healthy Japanese individuals. METHODS:Twenty healthy subjects (age range, 22-47 years) were recruited into this prospective, randomized, doubled-blind comparative stu...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,随机对照试验


    authors: Yoshizako H,Hara K,Takai Y,Kaidzu S,Obana A,Ohira A

    更新日期:2016-09-01 00:00:00

  • Global prevalence of asteroid hyalosis and projection of its future burden: a systematic review and meta-analysis.

    abstract::Asteroid hyalosis is defined by the presence of white, snowball-like non-crystalline vitreous opacities that move with the vitreous and appear to be anchored to its matrix. Asteroid hyalosis commonly occurs in the absence of other identifiable ocular abnormalities and is usually an incidental finding. The vitreous opa...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,评审


    authors: Møller-Lorentzen TB,Eckmann-Hansen C,Faber C,Larsen M,Subhi Y

    更新日期:2020-12-01 00:00:00

  • Pseudoexfoliation syndrome and relating factors in a rural Japanese population: the Kumejima Study.

    abstract:PURPOSE:To report the prevalence of pseudoexfoliation (PEX) syndrome and glaucoma associated with PEX (PEX-G) and their relating factors of them in a south-western island of Japan. METHODS:A population-based survey of all residents aged ≥ 40 years was conducted in Kumejima, Okinawa, Japan, and 3762 subjects (participa...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Arakaki Y,Sawaguchi S,Iwase A,Tomidokoro A,Araie M

    更新日期:2020-11-01 00:00:00

  • Topical dexamethasone-cyclodextrin nanoparticle eye drops for non-infectious Uveitic macular oedema and vitritis - a pilot study.

    abstract:PURPOSE:To evaluate the safety and efficacy of 1.5% dexamethasone nanoparticle (DexNP) drops in eyes with non-infectious uveitic macular oedema and vitritis. METHODS:In a prospective pilot study, DexNP drops were administered four times a day for 4 weeks followed by drops tapering over a period of another 4 weeks. Fol...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Shulman S,Jóhannesson G,Stefánsson E,Loewenstein A,Rosenblatt A,Habot-Wilner Z

    更新日期:2015-08-01 00:00:00

  • Retinal vascular fractal dimension and cerebral blood flow, a pilot study.

    abstract:PURPOSE:Ocular and brain microcirculation share embryological and histological similarities. The retinal vascular fractal dimension (FD) is a marker of retinal vascular complexity of the vascular tree. The purpose of this study was to explore the relationship between cerebral blood flow (CBF), retinal vascular FD and o...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Nadal J,Deverdun J,de Champfleur NM,Carriere I,Creuzot-Garcher C,Delcourt C,Chiquet C,Kawasaki R,Villain M,Ritchie K,Le Bars E,Daien V

    更新日期:2020-02-01 00:00:00

  • Plusoptix photoscreener use for paediatric vision screening in Flanders and Iran.

    abstract:PURPOSE:Photoscreening assesses risk factors for amblyopia, as an alternative to measurement of visual acuity (VA) to detect amblyopia, on the premise that its early correction could prevent development of amblyopia. We studied implementations of Plusoptix photoscreening in existing population-based screening in Flande...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,评审


    authors: Bostamzad P,Horwood AM,Schalij-Delfos NE,Boelaert K,de Koning HJ,Simonsz HJ

    更新日期:2020-02-01 00:00:00

  • Effects of multifocal soft contact lenses used to slow myopia progression on quality of vision in young adults.

    abstract:PURPOSE:To assess the effects of multifocal soft contact lenses (MF SCLs) used for myopia control on visual acuity (VA) and subjective quality of vision. METHODS:Twenty-four young adult myopes had baseline high and low-contrast VAs and refractions measured and quality of vision assessed by the Quality of Vision (QoV) ...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Kang P,McAlinden C,Wildsoet CF

    更新日期:2017-02-01 00:00:00

  • Variability in photocoagulation treatment of diabetic macular oedema.

    abstract:PURPOSE:To establish whether differences in the assessment of diabetic macular oedema (DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead to variability in the photocoagulation treatment of DME. METHODS:The differences in the assessment of DME with either OCT or stereoscopic biomicr...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: van Dijk HW,Verbraak FD,Kok PH,Oberstein SY,Schlingemann RO,Russell SR,Abràmoff MD

    更新日期:2013-12-01 00:00:00

  • Immunohistochemical assessment of mitotic count in uveal melanoma.

    abstract:BACKGROUND/AIMS:The mitotic count of uveal melanomas correlates with the risk of metastatic death, but with haematoxylin and eosin (H&E)-stained sections, it can be difficult to identify mitotic figures (MF) reliably. We investigated whether this measurement could be enhanced by immunohistochemistry, using the mitosis-...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Angi M,Damato B,Kalirai H,Dodson A,Taktak A,Coupland SE

    更新日期:2011-03-01 00:00:00

  • Macular perfusion velocities in the ocular ischaemic syndrome.

    abstract:PURPOSE:To assess retinal perfusion in eyes with unilateral ocular ischaemic syndrome (OIS) and to compare with control subjects. METHODS:Retrospective case series. Linear blood flow velocities in macular vessels were estimated using motion-contrast fundus photography in eight patients with unilateral OIS (eight OIS e...

    journal_title:Acta ophthalmologica



    authors: Klefter ON,Kofoed PK,Munch IC,Larsen M

    更新日期:2019-02-01 00:00:00

  • Retinal vessel diameter can reliably be determined in minipigs using Retinal Vessel Analyser with a microscope-mounted fundus camera.

    abstract:PURPOSE:Retinal Vessel Analyser (RVA) is a validated instrument to measure retinal vessel diameter in humans. The purpose of this study was to assess the reproducibility (inter-observer reliability) and the repeatability (test-retest reliability) of RVA with a microscope-mounted fundus camera to determine retinal vesse...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Papadopoulou DN,Mangioris G,Petropoulos IK,Mendrinos E,Mavropoulos A,Pournaras CJ

    更新日期:2012-06-01 00:00:00

  • Risk factors for the hypertensive phase after implantation of a glaucoma drainage device.

    abstract:PURPOSE:To investigate risk factors for the development of the hypertensive phase after implantation of the Ahmed glaucoma valve (AGV). METHODS:A total of 128 patients who had undergone AGV implantation were included in this study. The hypertensive phase was defined as intraocular pressure (IOP) > 21 mmHg during the f...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Jung KI,Park CK

    更新日期:2016-08-01 00:00:00

  • Subconjunctival bevacizumab for corneal neovascularization.

    abstract:PURPOSE:This work aimed to study and evaluate the effect of subconjunctival bevacizumab injection in patients with corneal neovascularization (CNV) resulting from different ocular surface disorders. METHODS:Ten eyes with CNV caused by different ocular surface disorders were studied. All eyes had both major and minor v...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Zaki AA,Farid SF

    更新日期:2010-12-01 00:00:00

  • Binocular vision alterations after refractive and cataract surgery: a review.

    abstract::To review binocular and accommodative disorders documented after corneal or intraocular refractive surgery, in normal healthy prepresbyopic patients. A bibliographic revision was performed; it included works published before 1st July 2017 where accommodation and/or binocularity was assessed following any type of refra...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,评审


    authors: García-Montero M,Albarrán Diego C,Garzón-Jiménez N,Pérez-Cambrodí RJ,López-Artero E,Ondategui-Parra JC

    更新日期:2019-03-01 00:00:00

  • Stroke risk among adult patients with third, fourth or sixth cranial nerve palsy: a Nationwide Cohort Study.

    abstract:PURPOSE:This study sought to determine whether isolated third, fourth and sixth cranial nerve palsies (NPs) are associated with increased short- and long-term risk of a subsequent stroke. METHODS:This was a nationwide retrospective propensity score-matched cohort study. A cohort of patients with NP (n = 466) and a ran...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,多中心研究


    authors: Rim TH,Han J,Choi YS,Lee T,Kim SS

    更新日期:2017-11-01 00:00:00

  • Optical coherence tomography evaluation of patients with macula-off retinal detachment after different postoperative posturing: a randomized pilot study.

    abstract:PURPOSE:To assess the presence of outer and inner retinal folds (RFs) and drop-out of the ellipsoid zone (EZ) occurring after surgical repair of macula-off rhegmatogenous retinal detachment (RRD) with different postoperative posture and preoperative use of adjuvant perfluorocarbon liquid (PFCO). METHODS:In this prospe...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Peiretti E,Nasini F,Buschini E,Caminiti G,Lesnik Oberstein SY,Willig A,Bijl HM,Mura M

    更新日期:2017-08-01 00:00:00

  • An 8-year follow-up of anti-vascular endothelial growth factor treatment with a treat-and-extend modality for neovascular age-related macular degeneration.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Berg K,Roald AB,Navaratnam J,Bragadóttir R

    更新日期:2017-12-01 00:00:00

  • Vitreomacular traction and exudative age-related macular degeneration.

    abstract::Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章,评审


    authors: Schulze S,Hoerle S,Mennel S,Kroll P

    更新日期:2008-08-01 00:00:00

  • Effects of ultrasound energy on the porcine corneal endothelium - Establishment of a phacoemulsification damage model.

    abstract:PURPOSE:The purpose of this study was to establish a standardized in vitro phacoemulsification damage model for future investigations of the effects of phacoemulsification, surgical devices, protective ophthalmic viscoelastic devices (OVDs), irrigation solutions and other aspects related to cataract phacoemulsification...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Kunzmann BC,Wenzel DA,Bartz-Schmidt KU,Spitzer MS,Schultheiss M

    更新日期:2020-03-01 00:00:00

  • Endoscopic dacryocystorhinostomy: long-term experience and outcomes.

    abstract:PURPOSE:To report our experience in endoscopic dacryocystorhinostomy in treating nasolacrimal duct obstruction over a 14-year period. METHODS:Retrospective case series carried out over a 14-year period from 1999 to 2014. A total of 624 endoscopic dacryocystorhinostomy procedures were performed in 442 patients who were...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Coumou AD,Genders SW,Smid TM,Saeed P

    更新日期:2017-02-01 00:00:00

  • Vasoproliferative retinal tumours in a Swedish population.

    abstract:PURPOSE:To describe the clinical appearance and the visual outcome of a cohort of patients with vasoproliferative retinal tumours (VPRTs) that were diagnosed and treated between 2002 and 2007 at the University Hospital of Örebro. METHODS:Nine patients with diagnosed VPRTs were included in a retrospective study. The me...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Makdoumi K,Crafoord S

    更新日期:2011-02-01 00:00:00

  • Physical activity and myopia in Danish children-The CHAMPS Eye Study.

    abstract:PURPOSE:To determine associations between physical activity (PA) and myopia in Danish school children and investigate the prevalence of myopia. METHODS:This is a prospective study with longitudinal data on PA in a Danish child cohort. Physical activity (PA) was measured objectively by repeated ActiGraph accelerometer ...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Lundberg K,Suhr Thykjaer A,Søgaard Hansen R,Vestergaard AH,Jacobsen N,Goldschmidt E,Lima RA,Peto T,Wedderkopp N,Grauslund J

    更新日期:2018-03-01 00:00:00

  • Retinal microvasculature in pituitary adenoma patients: is optical coherence tomography angiography useful?

    abstract:PURPOSE:To examine retinal vascular changes in the peripapillary and macular areas in patients with pituitary adenoma (PA) using optical coherence tomography angiography (OCTA). METHODS:Cross-sectional, retrospective study of 17 consecutive PA patients and 16 healthy subjects. All patients underwent a neuro-ophthalmol...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Dallorto L,Lavia C,Jeannerot AL,Shor N,Jublanc C,Boch AL,Bodaghi B,Tadayoni R,Touitou V,Bonnin S

    更新日期:2019-12-06 00:00:00

  • Phacoemulsification combined with posterior capsulorhexis and anterior vitrectomy in the management of malignant glaucoma in phakic eyes.

    abstract:PURPOSE:  To describe sequential phacoemulsification-intraocular lens (IOL) implantation-posterior capsulorhexis-anterior vitrectomy in the management of phakic malignant glaucoma. METHODS:  Twenty consecutive patients (25 eyes) with phakic malignant glaucoma were enrolled at the Zhongshan Ophthalmic Center, Sun Yat-s...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Liu X,Li M,Cheng B,Mao Z,Zhong Y,Wang D,Cao D,Yu F,Congdon NG

    更新日期:2013-11-01 00:00:00

  • Dynamics of big bubble formation in deep anterior lamellar keratoplasty by the big bubble technique: in vitro studies.

    abstract:PURPOSE:To examine the movement of air injected in the cornea in simulated deep anterior lamellar keratoplasty (DALK), from the needle tip to the formation of different types of big bubbles (BB) and to ascertain how air travels through the stroma and pre-Descemet's layer [Dua's layer (PDL)] to create a type-1 (air betw...

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Dua HS,Faraj LA,Kenawy MB,AlTaan S,Elalfy MS,Katamish T,Said DG

    更新日期:2018-02-01 00:00:00

  • Terson's syndrome as a prognostic factor for mortality of spontaneous subarachnoid haemorrhage.

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    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Sung W,Arnaldo B,Sergio C,Juliana S,Michel F

    更新日期:2011-09-01 00:00:00

  • Effects of peptide ratios in nanofibre-based hydrogels for the prevention of capsular opacification.

    abstract:PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....

    journal_title:Acta ophthalmologica

    pub_type: 杂志文章


    authors: Nibourg LM,Gelens E,Nibourg SA,de Jong MR,Kuijer R,van Kooten TG,Koopmans SA

    更新日期:2016-11-01 00:00:00