Abstract:
PURPOSE:To explore the association between retinal vein occlusion (RVO) and incident cancer. METHODS:All Danish citizens with a first-time diagnosis of RVO and no previous diagnosis of cancer in the period from 1 January 2004 to 31 December 2014 were included. Five likewise cancer-free, age- and gender-matched controls were included in a control cohort. All were followed up for 5 years or until either first diagnosis of cancer or death. Proportional hazards models with adjustment for age, gender, year of diagnosis and covariates and death as competing risk were used to estimate the risk of being diagnosed with cancer. RESULTS:There were 7963 RVO patients without cancer at the time of diagnosis, and all could be matched to likewise cancer-free controls. Half of RVO patients were male, and the median age at RVO diagnosis was 70 years (61-79). The control cohort was similar in terms of gender and age. The risk of cancer within 1 year was 1.8 among RVO patients and 1.5 among controls. The crude risk of cancer was 1.22 (1.11;1.34) and upon full adjustment 1.15 (1.05;1.27). No time dependency was detected, and the types of cancer developed in RVO patients and controls were similar. CONCLUSION:Retinal vein occlusion (RVO) diagnosis is associated with an increased risk of being diagnosed with cancer. This risk is likely to reflect shared risk factors rather than a causal association.
journal_name
Acta Ophthalmoljournal_title
Acta ophthalmologicaauthors
Toft-Petersen AP,Muttuvelu DV,Heegaard S,Torp-Pedersen Cdoi
10.1111/aos.13860subject
Has Abstractpub_date
2018-12-01 00:00:00pages
800-803issue
8eissn
1755-375Xissn
1755-3768journal_volume
96pub_type
杂志文章,多中心研究abstract:PURPOSE:Monthly dosing with ranibizumab (RBZ) is needed to achieve maximal visual gains in patients with neovascular ('wet') age-related macular degeneration (wAMD). In Sweden, dosing is performed as needed (RBZ PRN), resulting in suboptimal efficacy. Intravitreal aflibercept (IVT-AFL) every 2 months after three initia...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12964
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:The present study aimed to investigate and compare the psychometric properties of the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) and the Visual Function Index-14 (VF-14) in a large sample of patients with cataracts. METHODS:A total of 1052 patients with bilateral age-related catara...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2020-09-17 00:00:00
abstract:PURPOSE:To investigate the ability of mesenchymal stem cells (MSC) to transdifferentiate to corneal epithelial cells in experimental limbal stem cell deficiency in rabbits. METHODS:Total limbal stem cell deficiency was produced in 21 right eyes of 21 New Zealand rabbits; 6 eyes served as controls (group 1, G1). After ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01812.x
更新日期:2011-12-01 00:00:00
abstract:PURPOSE:Approximately 50% of patients with uveal melanomas develop metastases. Thus, it is important to improve our understanding of how melanoma metastases develop. METHODS:As part of a uveal melanoma micrometastasis study, we compared the detection rates of immunomagnetically selected (IMS) tumour cells in bone marr...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2012.02449.x
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abstract:PURPOSE:To evaluate the biomechanical properties of the cornea using Corneal Visualization Scheimpflug Technology (CorVis ST, Oculus) in eyes with primary open-angle glaucoma (POAG) and normal control eyes. METHODS:A comparative cross-sectional study that included 42 patients with POAG and 60 normal control subjects m...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12672
更新日期:2016-08-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1600-0420.2007.00940.x
更新日期:2008-02-01 00:00:00
abstract:PURPOSE:To evaluate the impact of pseudoexfoliation syndrome on intraocular lens (IOL) dislocation after phacoemulsification cataract surgery and explore possible associations related to surgical technique. METHODS:We systematically searched the MEDLINE, Embase, Web of Science, Cochrane, and Lilacs databases and grey ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,meta分析,评审
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更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To assess the trend patterns and gender disparity in global burden of vision loss due to diabetic retinopathy (DR) by year, age, region and socioeconomic status using prevalence and years lived with disability (YLDs) from Global Burden of Disease (GBD) study 2017. METHODS:Prevalence and YLDs data of vision los...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2020-10-29 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
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更新日期:2017-09-01 00:00:00
abstract:PURPOSE:To describe the concordance of keratoconus in 18 sets of twins. METHODS:Thirteen monozygotic (MZ) and five dizygotic (DZ) pairs of twins were identified during an investigation of familial keratoconus. We used 16 forensic microsatellite markers to confirm the zygosity of same sex twins. Patients and available ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2012.02448.x
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abstract:PURPOSE:Complex segregation analysis of 60 unrelated sporadic keratoconus (KC) families was performed to reveal the presumed mode of inheritance in our dataset. METHODS:Sixty probands, 212 family members and 212 age and gender matched healthy controls underwent clinical and videokeratographic examination. Family aggre...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12389
更新日期:2014-11-01 00:00:00
abstract:PURPOSE:To evaluate effectiveness, tolerability and safety of repeated intravitreal injections of 0.5 mg ranibizumab for the treatment of neovascular age-related macular degeneration in routine medical practice in Germany. METHODS:A noninterventional study with 3470 patients treated in 274 medical centres according to...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究
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更新日期:2013-09-01 00:00:00
abstract:PURPOSE:To study the effect of glaucoma drainage implant (GDI) surgery on corneal topography during the first postoperative year. METHODS:Twenty-one adult glaucoma patients were implanted with a Molteno3 or a Baerveldt 250 GDI. Corneal topography measurements were taken preoperatively and at 6 and 12 months after surg...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14247
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To investigate the cerebrospinal fluid (CSF) dynamics along the entire optic nerve (ON) in patients with normal-tension glaucoma (NTG). METHODS:Retrospective analysis of computed tomographic (CT) cisternographies in Caucasian patients with NTG. Fifty-six patients (99 of 112 eyes) fulfilled the diagnostic crite...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13647
更新日期:2018-08-01 00:00:00
abstract::The main purpose of this thesis was to examine whether the Danish National Patient Registry (NPR) could be used to monitor and assess the quality of cataract surgery in Denmark by studying the risks of two serious postoperative complications following cataract surgery - retinal detachment (RD) and postoperative endoph...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12676
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:To investigate risk factors for the development of the hypertensive phase after implantation of the Ahmed glaucoma valve (AGV). METHODS:A total of 128 patients who had undergone AGV implantation were included in this study. The hypertensive phase was defined as intraocular pressure (IOP) > 21 mmHg during the f...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12916
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:Chronic inflammation is involved in retinitis pigmentosa (RP). We demonstrated previously that intraocular inflammatory levels, as measured by slit-lamp ophthalmoscopy or laser flare photometry, are inversely correlated with central visual function in patients with RP. Here, we investigated the relationship bet...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13502
更新日期:2018-03-01 00:00:00
abstract:PURPOSE:To investigate the effects of cyclopentolate hydrochloride 1% on the main numerical parameters of anterior segment with Pentacam rotating Scheimpflug camera in children. SETTING:Ege University Faculty of Medicine, Department of Ophthalmology. METHODS:Pentacam measurements of 50 (23 boys and 27 girls) children...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2011.02122.x
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.01954.x
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abstract:PURPOSE:Elevated intra-ocular pressure (IOP) has been identified as a major risk factor for glaucoma. Additionally, extensive literature depicts a vascular dysfunction to exist in these patients. However, a large ocular blood flow-oriented trial to integrate these findings in the clinical setting is lacking. This study...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12962
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To report the functional and anatomical outcomes resulting from the use of intravitreal pegaptanib sodium (Macugen) in patients with diabetic macular oedema (DMO). METHODS:We conducted a retrospective outcome analysis, by optical coherence tomography (OCT) and best-corrected visual acuity (BCVA), of eyes with ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01580.x
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To establish whether differences in the assessment of diabetic macular oedema (DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead to variability in the photocoagulation treatment of DME. METHODS:The differences in the assessment of DME with either OCT or stereoscopic biomicr...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2012.02524.x
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:Choroideremia is an X-linked retinal disease characterized by early retinal pigment epithelium (RPE) loss and subsequent retinal degeneration. The RPE adopts either a smooth or mottled appearance on fundus autofluorescence (FAF). It is not known how RPE changes predict the health of the overlying ellipsoid zone...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.14281
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:The aim of the study was to describe the prevalence of visual impairment and retinopathy and to investigate risk factors for retinopathy in persons with diabetes, screen-detected diabetes, impaired glucose tolerance and normal glucose tolerance in a subpopulation of the HUNT study. METHODS:We used a sample (n ...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2010.01998.x
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:Angiogenic inhibitors, alone or combined with other therapies, are believed to represent a promising treatment for neovascularization in age-related macular degeneration (wet AMD). They can maintain or improve visual acuity (VA), at least for the first 2years. However, evolution to retinal atrophy cannot be rul...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/j.1755-3768.2009.01526.x
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of the ultrasonic circular cyclocoagulation procedure in patients with open-angle glaucoma naïve of previous filtering surgery. METHODS:Prospective non-comparative interventional clinical study conducted in five French University Hospitals. Thirty eyes of 30 patients with op...
journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2016-08-01 00:00:00
abstract:PURPOSE:The Gloucestershire Diabetic Eye Screening Programme offers annual digital photographic screening for diabetic retinopathy to a countywide population of people with diabetes. This study was designed to investigate progression of diabetic retinopathy in this programme of the English NHS Diabetic Eye Screening Pr...
journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12074
更新日期:2013-08-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.12135
更新日期:2013-11-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章
doi:10.1111/aos.13040
更新日期:2016-09-01 00:00:00
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journal_title:Acta ophthalmologica
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2018-06-01 00:00:00