Abstract：
:A lesion limited to the dorsal columns, at the level of L3-L4, was carried out in chronic cats. This operation produced a "partial axotomy" type of lesion on the ascending branches of Ia hind limb afferents. Two to six months after this operation, intracellular studies on L7-S1 motoneurons were carried out. Similar studies were done in normal animals. The peak amplitude and the rate of rise (dV/dt) of heteronymous EPSP's were studied during control conditions (sampling at 1 Hz) and during the post-tetanic potentiation produced by a 500 Hz tetanus (for 3 s). The analysis of these synaptic potentials makes us conclude that: The amplitude of the enlarged EPSP's, observed during PTP, seems to be linearly dependent on their amplitude during control (i.e., pre-tetanus) conditions. Judging by their amplitude, there is no difference between potentiated EPSP's of operated and normal animals. There is also a linear relationship between the rate of rise of EPSP's and their peak amplitude. The slope of this relationship becomes steeper after "partial axotomy", i.e., for a given EPSP amplitude, the dV/dt of its rising part is steeper in operated cats. This steeper slope is also present in EPSP's studied during PTP. The sharper rate of rise of EPSP's, induced by the "partial axotomy" of Ia fibers, would be the mechanism behind the larger monosynaptic reflex previously observed in these operated cats.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Decima EE,Lorenzo D,Mallach Ldoi
10.1007/BF00340482subject
Has Abstractpub_date
1986-01-01 00:00:00pages
464-8issue
3eissn
0014-4819issn
1432-1106journal_volume
64pub_type
杂志文章abstract：:Several recent studies indicate that saccades elicited in the absence of a visual target are slower than visually-guided movements of the same size. In addition, we have shown earlier that the slower saccades observed in two different paradigms had more asymmetrical (skewed) velocity profiles. Recently, it has been re...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00253624
更新日期：1989-01-01 00:00:00
abstract：:A wealth of evidence implicates the crossed descending projection from the superior colliculus (SC) in orientation and approach behaviours directed towards novel, non-noxious stimuli. In our preceding paper, we identified a population of nociceptive neurones in the rat SC that have axons that project to the contralate...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231781
更新日期：1996-05-01 00:00:00
abstract：:Identifying a stimulus as the target for a goal-directed movement involves inhibiting competing responses. Separable inhibitory interconnections bias local competition to ensure only one stimulus is selected and to alter movement initiation. Behavioural evidence of these inhibitory processes comes from the effects of ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1645-9
更新日期：2009-03-01 00:00:00
abstract：:The Stroop test enables interference between color naming and reading to be studied. Protopapas et al. (2007) reported more errors in an interference task and longer reaction times in 12.5-year-old dyslexics; also more Stroop interference with lower reading skills. The present study uses a version of the Stroop with f...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2247-x
更新日期：2010-06-01 00:00:00
abstract：:Transient changes in extracellular potassium concentration ([K+]o) and field potentials were evoked by 4-aminopyridine (4-AP; 50-100 microM) and recorded with ion-selective microelectrodes in CA1b, CA3b and dentate sectors of adult rat hippocampal slices. Long-lasting field potentials recurred at a frequency of approx...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228628
更新日期：1996-04-01 00:00:00
abstract：:We constructed average histograms from responses evoked by flashing stimuli and noted previously described variations in the shape of the response profile, particularly with respect to sharpness of the peak. To express this variable, we measured the half-rise latency, which is the latency from stimulus onset required ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00242177
更新日期：1995-01-01 00:00:00
abstract：:Repetitive finger tapping is a well-established clinical test for the evaluation of parkinsonian bradykinesia, but few studies have investigated other finger movement modalities. We compared the kinematic changes (movement rate and amplitude) and response to levodopa during a conventional index finger-thumb-tapping ta...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3491-7
更新日期：2013-06-01 00:00:00
abstract：:The present study was undertaken to investigate the effects of the alpha2 adrenergic agonist, clonidine, on the near complete cerebral ischemia (NCFI) evoked release of glutamate and aspartate from normo- and hyperglycemic rodent brain tissue using microdialysis tissue techniques. Hemodynamic variables, blood lactate,...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0064-4
更新日期：2005-12-01 00:00:00
abstract：:Primary gaze fixation is never perfectly stable but can be interrupted by involuntary, conjugate saccadic intrusions (SI). SI have a high prevalence in the normal population and are characterised by a horizontal fast eye movement away from the desired eye position, followed, after a variable duration, by a return sacc...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2209-2
更新日期：2005-07-01 00:00:00
abstract：:Experimental neurogenic tumors were induced transplacentally in rats by single injections of ethylnitrosourea (ENU). The resulting primary tumors as well as isogenic transplantation tumor lines and clonal cell lines derived therefrom were examined for their content of the brain specific protein 14-3-2 by a quantitativ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237328
更新日期：1976-05-10 00:00:00
abstract：:Quantitative autoradiography was used to examine central binding sites for L-[3H]glutamate in amygdaloid-kindled rats since receptors for excitatory amino acids have been implicated in epileptiform activity and seizure behaviors. In tissue from rats killed five days after two kindled seizures, the ipsilateral hippocam...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231751
更新日期：1991-01-01 00:00:00
abstract：:The vestibulo-ocular reflex (VOR) was intermittently suppressed by fixating a head-fixed target (light on: 9 s; darkness: 2 s) during whole-body (60-100 deg/s peak; 0.01-0.17 Hz) sinusoidal and triangular oscillation about the vertical axis for about 2 min. Eye movements associated with intervals of darkness at differ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00261343
更新日期：1985-01-01 00:00:00
abstract：:Fourteen healthy adults were tested to assess the potential influence on stance maintenance of two parts of the visual feedback technique (display scale and time delay). The task consisted in their keeping a spot on the screen representing their center of pressure, CoP (i.e. successive points of application of the gro...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-2288-8
更新日期：2005-08-01 00:00:00
abstract：:We measured the amount of information transmitted by the direction of two-dimensional (2-D) arm movements of human subjects, and by neuronal populations in the motor cortex and area 5 of monkeys. We also compared the information transmitted by a motor cortical population when the predictability of the direction of mov...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247577
更新日期：1988-01-01 00:00:00
abstract：:We describe a new form of gamma-aminobutyric acid (GABA) -mediated regulation of the inactivation and of the recovery from inactivation of the L-type Ca2+ current (I(Ca)) in crayfish muscle. GABA (1 mM) was applied during a 2-min period and the peak I(Ca) was measured using two-electrode voltage-clamp recordings 30 mi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000445
更新日期：2000-09-01 00:00:00
abstract：:Both human and animal research indicate that rapid eye movement sleep (REM) plays an important role in the processing of emotional information. REM is altered after fear conditioning in rats, but this alteration can be mitigated by exposure to a naïve conspecific. In addition, both the housing condition (isolated vs p...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3828-x
更新日期：2014-05-01 00:00:00
abstract：:The effects of intravenous doses (200 mug) of LSD on the activity of single neurones in the primary visual cortex have been studied in cats anaesthetized with urethane. Cells were stimulated with a bright bar of light moved over the receptive field, and orientation tuning was assessed quantitatively before and after a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00234826
更新日期：1977-01-18 00:00:00
abstract：:Muscle activity patterns in some complex human jaw muscles appear to be task sensitive. However, it is presently uncertain how changes in motor task affect motor unit (MU) behaviour in the human temporalis muscle. In this study, activity was recorded from 40 MUs in the anterior region of the muscle. The lowest sustain...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230303
更新日期：1993-01-01 00:00:00
abstract：:The effects of electrical stimulation of the cerebral cortex on the monosynaptic jaw closing and the disynaptic jaw opening reflexes were studied in cats anaesthetized with chloralose. The time course of the reflex effects was recorded. Similar rhythmic sequences of facilitation and inhibition were observed in both re...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237546
更新日期：1980-01-01 00:00:00
abstract：:Variations of the µ-opioid receptor gene OPRM1 have been shown to modulate pain perception with some evidence pointing towards a modulation of not only physical but also "psychological pain". In line with suggestions of a common neural network involved in the processing of physical pain and negative and distressing st...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4322-9
更新日期：2015-09-01 00:00:00
abstract：:Single fibre recordings were performed from the auditory nerve of the caiman, Caiman crocodilus. All neurones were spontaneously active (1-80 imp/s). Clicks evoked multiple peaks in the post stimulus time histogram spaced at 1/CF. At high intensities irregularities were observed. The latencies of the first peak observ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236735
更新日期：1980-01-01 00:00:00
abstract：:Peripheral sensory-motor neuropathy is one of the most frequent side effects of vincristine (VCR) administration, which often limits its usefulness in the treatment of a wide range of neoplastic diseases. The purpose of this work is to study VCR neurotoxicity in experimental animals from clinical, electrophysiological...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0499-2
更新日期：2006-08-01 00:00:00
abstract：:The effect of histamine administered via the common carotid artery on the transport processes of brain capillaries was investigated in rats. The fine structure of endothelial cells and the glial end-feet system was studied by electron microscopy and the serum albumin was visualized for light microscopy by the peroxida...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239384
更新日期：1982-01-01 00:00:00
abstract：:The retinal projections of the "non-image forming" system to the hypothalamus, anterodorsal thalamus and basal telencephalon were visualized in adult mink using the anterograde transport of cholera toxin conjugated to horseradish peroxidase injected intraocularly. A major and nearly symmetrical bilateral input of labe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228253
更新日期：1992-01-01 00:00:00
abstract：:In 11 squirrel monkeys (Saimiri sciureus), the brain stem was systematically explored with electrical brain stimulation for sites affecting the acoustic structure of ongoing vocalization. Vocalization was elicited by electrical stimulation of different brain structures. A severe deterioration of the acoustical structu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229880
更新日期：1992-01-01 00:00:00
abstract：:This study investigated the importance of binocular vision to foot placement accuracy when stepping onto a floor-based target during gait initiation. Starting from stationary, participants placed alternate feet onto targets sequentially positioned along a straight travel path with the added constraint that the initial...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2910-x
更新日期：2012-01-01 00:00:00
abstract：:According to the peak and decline model divergent thinking declines at a specific age (in or after middle age). However, if divergent thinking declines steadily in aging still has to be clarified. In order to explore the age-related changes in verbal and visual divergent thinking, in the present study a sample of 159 ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4857-4
更新日期：2017-04-01 00:00:00
abstract：:Organotypic slice cultures of striatum and neocortex were prepared from newborn to seven day old rats and cultured for three to 60 days. When processed for tyrosine hydroxylase (TH) immunocytochemistry medium-sized, aspiny TH immunoreactive (TH-i) neurons with a similar morphology were revealed in the striatum and the...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231159
更新日期：1991-01-01 00:00:00
abstract：:Sensitivity to many visual stimuli, and, in particular, image displacement, is reduced during a change in fixation (saccade) compared to when the eye is still. In these experiments, we studied the sensitivity of observers to ecologically relevant image translations of large, complex, real world scenes either during ho...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-2120-y
更新日期：2010-04-01 00:00:00
abstract：:In order to see whether septal neurones are connected to the hypothalamic neurones secreting vasopressin or oxytocin, neurones in different regions of the septum were recorded during electrical stimulation of the supraoptic nucleus. The position of the stimulating electrode within the latter was verified using lactati...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237493
更新日期：1981-01-01 00:00:00
