Genetic and pharmacological inhibition of eIF4E effectively targets esophageal cancer cells and augments 5-FU's efficacy.

abstract：:Lung transplantation is the only therapeutic option for end-stage pulmonary failure. Nevertheless, the shortage of donor pool available for transplantation does not allow to satisfy the requests, thus the mortality on the waiting list remains high. One of the tools to overcome the donor pool shortage is the use of ex-...

journal_title：Journal of thoracic disease

authors： Rosso L,Zanella A,Righi I,Barilani M,Lazzari L,Scotti E,Gori F,Mendogni P

更新日期：2018-07-01 00:00:00

abstract：Background:Interatrial block (IAB) has been previously shown to predict atrial fibrillation (AF) in cardiac populations. This study sought to evaluate the relationship between IAB and new-onset AF in a population of patients undergoing clinically indicated coronary angiography who received carotid ultrasonography. Met...

journal_title：Journal of thoracic disease

authors： Alexander B,Baranchuk A,Haseeb S,van Rooy H,Kuchtaruk A,Hopman W,Çinier G,Hetu MF,Li TY,Johri AM

更新日期：2018-07-01 00:00:00

abstract：:Cerebral oximetry based on near-infrared spectroscopy (NIRS) is increasingly used during the perioperative period of cardiovascular operations. It is a noninvasive technology that can monitor the regional oxygen saturation of the frontal cortex. Current literature indicates that it can stratify patients preoperatively...

journal_title：Journal of thoracic disease

authors： Vretzakis G,Georgopoulou S,Stamoulis K,Stamatiou G,Tsakiridis K,Zarogoulidis P,Katsikogianis N,Kougioumtzi I,Machairiotis N,Tsiouda T,Mpakas A,Beleveslis T,Koletas A,Siminelakis SN,Zarogoulidis K

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Rapid on-site evaluation (ROSE) of cytologic specimens is a useful ancillary technique in needle aspiration procedures of pulmonary/mediastinal lesions, but few reports had been carried out to confirm the utility in the diagnosis of peripheral pulmonary lesions (PPLs) by radial probe endobronchial ultrasound...

journal_title：Journal of thoracic disease

authors： Chen CH,Cheng WC,Wu BR,Chen CY,Chen WC,Hsia TC,Liao WC,Tu CY,Shih CM,Hsu WH,Wang KP

更新日期：2015-12-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) associates with several extra-pulmonary effects. Muscle dysfunction and wasting is one of the most prominent extra-pulmonary effects and contributes to exercise limitation and health related quality of life (HRQoL), morbidity as well as mortality. The loss of muscle mass is...

journal_title：Journal of thoracic disease

authors： Lakhdar R,Rabinovich RA

更新日期：2018-05-01 00:00:00

abstract：:Radical radiotherapy remains the cornerstone of treatment for patients with unresectable locally advanced non small cell lung cancer (NSCLC) either as single modality treatment for poor performance status patients or with sequential or concomitant chemotherapy for good performance status patients. Advances in understa...

journal_title：Journal of thoracic disease

authors： McDonald F,Popat S

更新日期：2014-04-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is the most common cause of interstitial lung disease (ILD) and carries a worse prognosis than many cancers. Until recently, there were no active treatment options available for patients with IPF, meaning palliation or lung transplantation in selected patients were the only options....

journal_title：Journal of thoracic disease

authors： Shaw J,Marshall T,Morris H,Hayton C,Chaudhuri N

更新日期：2017-11-01 00:00:00

abstract：:In 2011, three authoritative academic communities, International Association for the Study of Lung Cancer, the American Thoracic Society, and the European Respiratory Society (IASLC/ATS/ERS), published a novel lung adenocarcinoma histologic classification. The major modifications of this classification include the abo...

journal_title：Journal of thoracic disease

authors： Tang Y,He Z,Zhu Q,Qiao G

更新日期：2014-10-01 00:00:00

abstract：Background:Endoscopic thoracic sympathectomy (ETS) has not been widely adopted for treating craniofacial hyperhidrosis (CFH) due to its known postoperative complication, compensatory hyperhidrosis (CH). In this study, we evaluated whether the autonomic nerve analysis data via pre-ETS heart rate variability (HRV) test c...

journal_title：Journal of thoracic disease

authors： Moon DH,Kang DY,Lee HS,Lee JW,Lee YJ,Lee S

更新日期：2020-05-01 00:00:00

abstract：Background:Although emphysema and small cell lung cancer (SCLC) are prevalent in smokers, no previous study has investigated the prognostic impact of computed tomography (CT)-determined emphysema in SCLC. This study was undertaken to analyze the prognostic value of emphysema scores as determined by baseline CT scans in...

journal_title：Journal of thoracic disease

authors： Lee HY,Kim EY,Kim YS,Ahn HK,Kim YK

更新日期：2018-02-01 00:00:00

abstract：:More than half of primary lung cancers are not resectable at diagnosis and 40% of deaths may be secondary to loco-regional disease. Many of these patients suffer from symptoms related to airways obstruction. Indications for therapeutic endoscopic treatment are palliation of dyspnea and other obstructive symptoms in ad...

journal_title：Journal of thoracic disease

authors： Scarlata S,Fuso L,Lucantoni G,Varone F,Magnini D,Antonelli Incalzi R,Galluccio G

更新日期：2017-08-01 00:00:00

abstract：:The selection of appropriate recipients for lung transplantation is an evolving discipline. As experience with the procedure has developed over the last decades, the identification of transplant candidates has also changed as transplant centers strive to safely provide the therapy to as many patients possible. The Int...

journal_title：Journal of thoracic disease

authors： Weill D

更新日期：2018-07-01 00:00:00

abstract：Background:Reconstruction of the aorto-mitral curtain (AMC) for invasive double-valve infective endocarditis (IE) is a rare and challenging procedure. This study presents the short- and mid-term results of reconstruction of AMC in a single center. Methods:From 2016 to 2019, 14 patients with invasive double-valve under...

journal_title：Journal of thoracic disease

authors： Jiang X,Liu J,Khan F,Tang R,Zhang Y,Gu T

更新日期：2020-04-01 00:00:00

abstract：:Transcatheter procedures offer less invasive approaches allowing rapid recovery and earlier hospital discharge. A number of international guidelines have defined the role of echocardiography spanning diagnosis, detailed anatomical assessment, device sizing and selection, peri-procedure guidance and post device surveil...

journal_title：Journal of thoracic disease

authors： Rana BS

更新日期：2018-09-01 00:00:00

abstract：:Implementing a new technical process demands a complex preparation. In cardiac surgery this complex preparation is often reduced to visiting a surgeon who is familiar with a technique. The science of learning has identified that several steps are needed towards a successful implementation. The first step is the creati...

journal_title：Journal of thoracic disease

authors： Sergeant P

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to reveal the short-term outcomes of video-assisted thoracoscopic surgery (VATS) segmentectomy without tracheal intubation compared with intubated general anesthesia with one-lung ventilation (OLV). METHODS:We performed a retrospective review of our institutional database of consec...

journal_title：Journal of thoracic disease

authors： Guo Z,Yin W,Pan H,Zhang X,Xu X,Shao W,Chen H,He J

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The characteristics of patients with urinothorax (UT) are poorly defined. METHODS:A systematic review was performed searching for studies reporting clinical findings, pleural fluid (PF) characteristics, and the most effective treatment of UT. Case descriptions and retrospective studies were included. RESUL...

journal_title：Journal of thoracic disease

authors： Toubes ME,Lama A,Ferreiro L,Golpe A,Álvarez-Dobaño JM,González-Barcala FJ,San José E,Rodríguez-Núñez N,Rábade C,Lourido T,Valdés L

更新日期：2017-05-01 00:00:00

abstract：:Sensory information arising from the airways is processed in a distributed brain network that encodes for the discriminative and affective components of the resultant sensations. These higher brain networks in turn regulate descending motor control circuits that can both promote or suppress behavioural responses. Here...

journal_title：Journal of thoracic disease

authors： McGovern AE,Ajayi IE,Farrell MJ,Mazzone SB

更新日期：2017-10-01 00:00:00

abstract：Background:Sleeve resection allows for preservation of lung parenchyma and improved long-term outcomes when compared with pneumonectomy. Little is known about minimally invasive sleeve resection, especially indications, feasibility, technical aspects, complications, and outcomes. We reviewed our institutional experienc...

journal_title：Journal of thoracic disease

authors： Caso R,Watson TJ,Khaitan PG,Marshall MB

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the effectiveness and safety of diagnostic flexi-rigid thoracoscopy in differentiating exudative pleural effusion of unknown etiology. METHODS:A total of 215 patients with undiagnosed exudative pleural effusion were consecutively recruited between January 2011 and Febru...

journal_title：Journal of thoracic disease

authors： Gao BA,Zhou G,Guan L,Zhang LY,Xiang GM

更新日期：2014-05-01 00:00:00

abstract：:Histological characteristics and clinical behaviour define lung neuroendocrine tumors (NETs), which are classified into four groups: typical (TC) and atypical carcinoids (AC), large-cell neuroendocrine carcinomas (LCNCs) and small-cell lung cancers (SCLCs). Historically, outcome and treatment of these rare neoplasms h...

journal_title：Journal of thoracic disease

authors： Filosso PL,Falcoz PE,Solidoro P,Pellicano D,Passani S,Guerrera F,Ruffini E,ESTS Lung Neuroendocrine Working-Group Participating Centers*.

更新日期：2018-10-01 00:00:00

abstract：:Lung transplantation is the gold standard therapy for patients with end-stage lung disease. The use of the lung allocation score (LAS) has permitted improved allocation of scarce pulmonary allografts. Recently, Crawford et al. examined the experience in the United States in lung transplantation in candidates with the ...

journal_title：Journal of thoracic disease

authors： Mulvihill MS,Hartwig MG,Daneshmand MA

更新日期：2017-09-01 00:00:00

abstract：Background:Good compliance in chronic obstructive pulmonary disease (COPD) is of 'paramount importance' in reducing the occurrence of acute exacerbations, hospitalisation and mortality and in improving quality of life. However, a number of studies have confirmed that long-term compliance is low and often associated wit...

journal_title：Journal of thoracic disease

authors： O'Hagan P,Dederichs J,Viswanad B,Gasser M,Walda S

更新日期：2018-10-01 00:00:00

abstract：Background:Postoperative air leaks are the most common complication after a pulmonary resection. There is no data in the literature comparing the traditional and digital chest drainage system after a robotic-assisted pulmonary lobectomy. Methods:This was a retrospective, correlational study. Medical records from 182 e...

journal_title：Journal of thoracic disease

authors： Jacobsen K,Talbert S,Boyer JH

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Several studies have demonstrated that reduced lung function is a significant risk factor for lung cancer and increased surgical risk in patients with operable stages of lung cancer. The aim of the study was to perform pulmonary function tests and investigate which is a favorable respiratory function test fo...

journal_title：Journal of thoracic disease

authors： Zarogoulidis P,Kerenidi T,Huang H,Kontakiotis T,Tremma O,Porpodis K,Kalianos A,Rapti A,Foroulis C,Zissimopoulos A,Courcoutsakis N,Zarogoulidis K

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Lung cancer is a leading cause of death worldwide. Considerable studies have reported that NADPH oxidase (NOX) expression or activity may play an important role in the tumorigenesis of lung cancer. However, the results are inconsistent. Thus, a systematic review and meta-analysis were conducted in this study...

journal_title：Journal of thoracic disease

authors： Han M,Zhang T,Yang L,Wang Z,Ruan J,Chang X

更新日期：2016-07-01 00:00:00

abstract：Background:The development of minimally invasive surgical approaches has revolutionized surgical care and greatly improved surgical outcomes. This study aimed to evaluate the clinical effectiveness of a powered vascular stapler (PVS) during video-assisted thoracoscopic surgery (VATS) lobectomy. Methods:This prospectiv...

journal_title：Journal of thoracic disease

authors： Qiu B,Kang X,Chen KN,Hu J,Li J,Zeng L,Fegelman EJ,Schwiers ML,Creedon EE,Waggoner JR,Ding D,Yang T,Gao S

更新日期：2019-05-01 00:00:00

abstract：:Presented is a rare case of a primary melanoma of the lung in an 89 year old male patient. Primary melanoma of the lung has been previously reported in the English literature in about 30 patients. Surgical resection either with lobectomy of pneumonectomy and a lymph node dissection has been shown to be the best chance...

journal_title：Journal of thoracic disease

authors： Seitelman E,Donenfeld P,Kay K,Takabe K,Andaz S,Fox S

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:With the widespread use of computed tomography (CT), the frequency of discovering ground glass opacity (GGO) pulmonary lesions has increased. There have been some reports on surgery or transthoracic needle aspiration (TTNA) for diagnostic sampling of GGOs but none on transbronchial biopsy (TBB). The purpose ...

journal_title：Journal of thoracic disease

authors： Izumo T,Sasada S,Chavez C,Tsuchida T

更新日期：2013-12-01 00:00:00

abstract：:Protocols for the management of air leaks are critical aspects in the postoperative course of patients following lung resections. Many investigations in the last decade are focusing on the chest tube modalities or preventative measures, however, little is known about the pathophysiology of air leak and the patient per...

journal_title：Journal of thoracic disease

authors： Pompili C,Miserocchi G

更新日期：2016-02-01 00:00:00