Abstract:
BACKGROUND:With the widespread use of computed tomography (CT), the frequency of discovering ground glass opacity (GGO) pulmonary lesions has increased. There have been some reports on surgery or transthoracic needle aspiration (TTNA) for diagnostic sampling of GGOs but none on transbronchial biopsy (TBB). The purpose of this study was to evaluate the diagnostic utility of chest tomosynthesis images and TBB through endobronchial ultrasonography with a guide sheath (EBUS-GS) for GGO. METHODS:This study included 40 patients (19 men, 21 women; age 66.9±8.7 years, mean ± standard deviation, SD). The mean lesion diameter was 22±10 mm (mean ± SD). Chest tomosynthesis images served as maps prior to bronchoscopic sampling using radial EBUS probe with a guide sheath kit. RESULTS:The overall diagnostic yield of EBUS-GS-guided TBB was 65.0% (26 of 40 lesions). In a multivariate analysis, diagnostic yield of lesions with EBUS images (79.2%, 19 of 24 cases) was significantly higher than those lesions without EBUS images detected (43.8%, 7 of 16 cases) (P=0.017). Detectability on chest tomosynthesis was not a significant contributing factor. Only one complication was observed: pneumothorax that did not require chest tube drainage. CONCLUSIONS:TBB through EBUS-GS can be considered as one of the diagnostic methods for GGO. Further technological development is required to identify the location of the target GGO lesion more precisely.
journal_name
J Thorac Disjournal_title
Journal of thoracic diseaseauthors
Izumo T,Sasada S,Chavez C,Tsuchida Tdoi
10.3978/j.issn.2072-1439.2013.11.30subject
Has Abstractpub_date
2013-12-01 00:00:00pages
745-50issue
6eissn
2072-1439issn
2077-6624pii
jtd-05-06-745journal_volume
5pub_type
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