Lung transplantation in the most critically-III: forging ahead.

Abstract:

:Lung transplantation is the gold standard therapy for patients with end-stage lung disease. The use of the lung allocation score (LAS) has permitted improved allocation of scarce pulmonary allografts. Recently, Crawford et al. examined the experience in the United States in lung transplantation in candidates with the highest LAS, demonstrating that outcomes for candidates with the highest LAS scores have improved significantly. This editorial places these data in the broader context of thoracic transplantation, and highlights the critical need for ongoing examination of this critically-ill patient population.

journal_name

J Thorac Dis

authors

Mulvihill MS,Hartwig MG,Daneshmand MA

doi

10.21037/jtd.2017.08.12

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

3430-3432

issue

9

eissn

2072-1439

issn

2077-6624

pii

jtd-09-09-3430

journal_volume

9

pub_type

评论,杂志文章
  • Sequencing postoperative radiotherapy and adjuvant chemotherapy in non-small cell lung cancer: unanswered questions on the not evidence-based approach.

    abstract::This editorial comments on the study by Lee et al. which reported on the use of postoperative radiotherapy (PORT) as first strategy after resection of stage IIIA-pN2 non-small cell lung cancer (NSCLC). After completion of PORT, 41% of patients received postoperative chemotherapy (POCT). The five-year overall survival ...

    journal_title:Journal of thoracic disease

    pub_type: 评论,杂志文章

    doi:10.21037/jtd.2016.05.76

    authors: Kepka L,Socha J,Rucinska M,Wasilewska-Tesluk E,Komosinska K

    更新日期:2016-07-01 00:00:00

  • Awake extracorporeal membrane oxygenation in patients with severe postoperative acute respiratory distress syndrome.

    abstract:BACKGROUND:A clinical trial of extracorporeal membrane oxygenation (ECMO) as an alternative ventilator tool is being performed as a new indication for ECMO. The purpose of this study was to evaluate the feasibility of awake ECMO to increase the success rate of weaning patients from ECMO and ventilator care during treat...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2016.01.32

    authors: Yeo HJ,Cho WH,Kim D

    更新日期:2016-01-01 00:00:00

  • To avoid compensatory hyperhidrosis after sympathetic surgery for craniofacial hyperhidrosis.

    abstract:Background:Endoscopic thoracic sympathectomy (ETS) has not been widely adopted for treating craniofacial hyperhidrosis (CFH) due to its known postoperative complication, compensatory hyperhidrosis (CH). In this study, we evaluated whether the autonomic nerve analysis data via pre-ETS heart rate variability (HRV) test c...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2020.03.28

    authors: Moon DH,Kang DY,Lee HS,Lee JW,Lee YJ,Lee S

    更新日期:2020-05-01 00:00:00

  • Albert-Lembert versus hybrid-layered suture in hand sewn end-to-end cervical esophagogastric anastomosis after esophageal squamous cell carcinoma resection.

    abstract:BACKGROUND:Hand sewn cervical esophagogastric anastomosis (CEGA) is regarded as preferred technique by surgeons after esophagectomy. However, considering the anastomotic leakage and stricture, the optimal technique for performing this anastomosis is still under debate. METHODS:Between November 2010 and September 2012,...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2015.11.09

    authors: Feng F,Sun L,Xu G,Hong L,Yang J,Cai L,Li G,Guo M,Lian X,Zhang H

    更新日期:2015-11-01 00:00:00

  • Clinical utility of robot-assisted transthoracic esophagectomy in advanced esophageal cancer after neoadjuvant chemoradiation therapy.

    abstract:Background:Although robot-assisted minimally-invasive esophagectomy (RAMIE) surgeries are expanding clinically, few studies have reported patients with locally-advanced esophageal cancer who underwent neoadjuvant chemoradiation therapy (nCRT). Methods:From 2013 to 2017, 219 patients with esophageal squamous cell carci...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2019.07.53

    authors: Yun JK,Lee IS,Gong CS,Kim BS,Kim HR,Kim DK,Park SI,Kim YH

    更新日期:2019-07-01 00:00:00

  • Suberoylanilide hydroxamic acid attenuates paraquat-induced pulmonary fibrosis by preventing Smad7 from deacetylation in rats.

    abstract:BACKGROUND:Recent evidence suggests that a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), has anti-fibrotic effect. However, the exact mechanism of its anti-fibrotic potential remains is unclear. In this study, we investigated the molecular mechanism of SAHA in attenuating pulmonary fibrosis by ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.08.08

    authors: Rao SS,Zhang XY,Shi MJ,Xiao Y,Zhang YY,Wang YY,Zhang CZ,Shao SJ,Liu XM,Guo B

    更新日期:2016-09-01 00:00:00

  • Autonomic dysfunction in patients with chronic obstructive pulmonary disease (COPD).

    abstract::It has been recognized that chronic obstructive pulmonary disease (COPD) is a systemic disease which has been shown to negatively affect the cardiovascular and autonomic nerve system. The complexity of the physiologic basis by which autonomic dysfunction occurs in patients with COPD is considerable and the knowledge i...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2010.02.04.5

    authors: van Gestel AJ,Steier J

    更新日期:2010-12-01 00:00:00

  • Liquid biopsy is a valuable tool in the diagnosis and management of lung cancer.

    abstract::Liquid biopsy refers to the use of various body fluids to test for circulating biological elements derived from the tumor. Liquid biopsy has taken on an increasingly important role in lung cancer diagnosis, molecular characterization, surveillance, monitoring, and determining mechanisms of resistance. These assays can...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.21037/jtd.2020.04.20

    authors: Cecchini MJ,Yi ES

    更新日期:2020-11-01 00:00:00

  • Inframammary approach for addressing anterior mediastinal tumours: initial experience.

    abstract:Background:Anterior mediastinal tumours account for 50% of all mediastinal masses. Surgical intervention is the standard approach for their diagnosis or treatment. Minimally invasive techniques have gained significant popularity in the last few decades due to the obvious advantages that they offer. We will describe a s...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd-19-3310b

    authors: Ferreira R,Junqueira N,Rodrigues M,Nobre Â

    更新日期:2020-05-01 00:00:00

  • Glucose-insulin-potassium correlates with hemodynamic improvement in patients with septic myocardial dysfunction.

    abstract:BACKGROUND:Glucose-insulin-potassium (GIK) demonstrates a cardioprotective effect by providing metabolic support and anti-inflammatory action, and may be useful in septic myocardial depression. The aim of this study was to examine the relationship between GIK and hemodynamic outcomes in septic shock patients with myoca...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.12.10

    authors: Kim WY,Baek MS,Kim YS,Seo J,Huh JW,Lim CM,Koh Y,Hong SB

    更新日期:2016-12-01 00:00:00

  • Results of the introduction of a minimally invasive esophagectomy program in a tertiary referral center.

    abstract:BACKGROUND:Esophagectomy is accompanied by a high postoperative complication rate. Minimally invasive esophageal surgery appears to be a promising technique that might be associated with a lower pulmonary morbidity rate. The objective of this study was to describe the implementation of minimally invasive esophageal sur...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2012.09.05

    authors: Blom RL,Klinkenbijl JH,Hollmann MW,Bergman JJ,Cuesta MA,Bemelman WA,Busch OR,van Berge Henegouwen MI

    更新日期:2012-10-01 00:00:00

  • Detection, classification, and management of rejection after lung transplantation.

    abstract::Rejection is a major complication following lung transplantation. Acute cellular rejection, lymphocytic bronchiolitis, and antibody-mediated rejection (AMR) are all risk factors for the subsequent development of chronic lung allograft dysfunction (CLAD). Acute cellular rejection and lymphocytic bronchiolitis have well...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.21037/jtd.2019.03.83

    authors: Parulekar AD,Kao CC

    更新日期:2019-09-01 00:00:00

  • Comprehensive analysis of EGFR T790M detection by ddPCR and ARMS-PCR and the effect of mutant abundance on the efficacy of osimertinib in NSCLC patients.

    abstract:Background:Patients with non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations often develop systemic disease progression during treatment with EGFR-tyrosine kinase inhibitors (TKIs). Droplet digital polymerase chain reaction (ddPCR) and amplification refractory mutation system ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2019.07.42

    authors: Li Y,Xu Y,Wu X,He C,Liu Q,Wang F

    更新日期:2019-07-01 00:00:00

  • Ultrasound techniques in the evaluation of the mediastinum, part 2: mediastinal lymph node anatomy and diagnostic reach of ultrasound techniques, clinical work up of neoplastic and inflammatory mediastinal lymphadenopathy using ultrasound techniques and h

    abstract::Ultrasound imaging has gained importance in pulmonary medicine over the last decades including conventional transcutaneous ultrasound (TUS), endoscopic ultrasound (EUS), and endobronchial ultrasound (EBUS). Mediastinal lymph node (MLN) staging affects the management of patients with both operable and inoperable lung c...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.3978/j.issn.2072-1439.2015.10.08

    authors: Jenssen C,Annema JT,Clementsen P,Cui XW,Borst MM,Dietrich CF

    更新日期:2015-10-01 00:00:00

  • Anomalous origin of the left coronary artery from the pulmonary artery diagnosed during transcatheter treatment of severe pulmonary branch stenoses: a potentially life-threatening situation.

    abstract::We report an 8-year-old female undergoing interventional catheterization for treatment of pulmonary artery stenoses, atrial septal defect and patent ductus arteriosus. Anomalous left coronary artery arising from the pulmonary artery was diagnosed during the procedure. We highlight the importance of recognizing this ra...

    journal_title:Journal of thoracic disease

    pub_type:

    doi:10.21037/jtd.2018.05.20

    authors: Robinson L,Baruteau AE,Fraisse A

    更新日期:2018-05-01 00:00:00

  • Urinothorax: a systematic review.

    abstract:BACKGROUND:The characteristics of patients with urinothorax (UT) are poorly defined. METHODS:A systematic review was performed searching for studies reporting clinical findings, pleural fluid (PF) characteristics, and the most effective treatment of UT. Case descriptions and retrospective studies were included. RESUL...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2017.04.22

    authors: Toubes ME,Lama A,Ferreiro L,Golpe A,Álvarez-Dobaño JM,González-Barcala FJ,San José E,Rodríguez-Núñez N,Rábade C,Lourido T,Valdés L

    更新日期:2017-05-01 00:00:00

  • What can individuals do to reduce personal health risks from air pollution?

    abstract::In many areas of the world, concentrations of ambient air pollutants exceed levels associated with increased risk of acute and chronic health problems. While effective policies to reduce emissions at their sources are clearly preferable, some evidence supports the effectiveness of individual actions to reduce exposure...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.3978/j.issn.2072-1439.2014.12.21

    authors: Laumbach R,Meng Q,Kipen H

    更新日期:2015-01-01 00:00:00

  • Pulmonary emphysema is associated with fungal sensitization in asthma.

    abstract:Background:Fungal sensitization is a risk factor for severe asthma. Colonization in the lower respiratory tract is one of the forms of fungal exposure, and it is related to fungal sensitization. Pulmonary emphysema was recently reported to be an underlying disease of fungal colonization. The aim of study was to evaluat...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd-20-995

    authors: Kono Y,To M,Tsuzuki R,Yamawaki S,Soeda S,To Y

    更新日期:2020-10-01 00:00:00

  • Independent factors related to preoperative acute lung injury in 130 adults undergoing Stanford type-A acute aortic dissection surgery: a single-center cross-sectional clinical study.

    abstract:Background:Previous retrospective study suggested that acute lung injury (ALI) is frequent (78.49%) in patients undergoing aortic dissection surgery, and accompanied by a number of untoward consequences, and even induces death. Methods:This prospective single-center cross-sectional study, registered in the ClinicalTri...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2018.06.140

    authors: Pan X,Lu J,Cheng W,Yang Y,Zhu J,Jin M

    更新日期:2018-07-01 00:00:00

  • McKeown or Ivor Lewis totally minimally invasive esophagectomy for cancer of the esophagus and gastroesophageal junction: systematic review and meta-analysis.

    abstract:BACKGROUND:Minimally invasive esophagectomy (MIE) has consistently been associated with improved perioperative outcome and similar oncological safety compared to open esophagectomy. However, it is currently unclear what type of MIE is preferred for patients with resectable esophageal cancer. METHODS:Literature was sea...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2017.03.173

    authors: van Workum F,Berkelmans GH,Klarenbeek BR,Nieuwenhuijzen GAP,Luyer MDP,Rosman C

    更新日期:2017-07-01 00:00:00

  • Lentivirus vector-mediated Rho guanine nucleotide dissociation inhibitor 2 overexpression induces beta-2 adrenergic receptor desensitization in airway smooth muscle cells.

    abstract:BACKGROUND:Beta-2 adrenergic receptor (β2AR) downregulation is critical to asthma rescue therapy; however, tolerance, also known as β2AR or bronchodilator desensitization, mechanisms potentially resulting in life-threatening rescue treatment failure remain poorly understood. METHODS:Airway smooth muscle cells (ASMCs) ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2013.10.07

    authors: Ni S,Zhang Y,Wang H,Zhou J,Ding L,Liu H

    更新日期:2013-10-01 00:00:00

  • Effectiveness and safety of diagnostic flexi-rigid thoracoscopy in differentiating exudative pleural effusion of unknown etiology: a retrospective study of 215 patients.

    abstract:BACKGROUND:The aim of this study was to evaluate the effectiveness and safety of diagnostic flexi-rigid thoracoscopy in differentiating exudative pleural effusion of unknown etiology. METHODS:A total of 215 patients with undiagnosed exudative pleural effusion were consecutively recruited between January 2011 and Febru...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2014.02.09

    authors: Gao BA,Zhou G,Guan L,Zhang LY,Xiang GM

    更新日期:2014-05-01 00:00:00

  • Nm23-H1 was involved in regulation of KAI1 expression in high-metastatic lung cancer cells L9981.

    abstract:BACKGROUND:The tetraspanin KAI1/CD82 was identified as a tumor metastasis suppressor that down-regulated in malignant progression of lung cancer. However, the underlying mechanism of anti-metastasis role of KAI1 in lung cancer is hardly known. In this paper, we sought to study the function and regulatory mechanism of K...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.04.59

    authors: You J,Chang R,Liu B,Zu L,Zhou Q

    更新日期:2016-06-01 00:00:00

  • Addition to inhaled corticosteroids of leukotriene receptor antagonists versus theophylline for symptomatic asthma: a meta-analysis.

    abstract:BACKGROUND:Inhaled corticosteroids (ICSs) are widely used in combination with second controller medications in the management of asthma in adults and children. There lacks a systematic comparison between addition of leukotriene receptor antagonists (LTRAs) and theophylline to ICS. The purpose of this meta-analysis was ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2015.04.12

    authors: Chen X,Kang YB,Wang LQ,Li Y,Luo YW,Zhu Z,Chen R

    更新日期:2015-04-01 00:00:00

  • Preliminary evaluation and discussion of the safety of left innominate vein resection.

    abstract:Background:To evaluate the safety of resection of anterior mediastinal lesions involving the left innominate vein (LIV) and analyze the risk factors affecting LIV resection safety. Methods:Patients who underwent anterior mediastinal lesion and LIV resection from January 2010 to December 2018 in the Department of Thora...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2020.01.29

    authors: Wang HQ,Tian F,Wei M,Chen LH,Cheng SY,Feng Z,Ma J,Zhang TY,Guo YZ,Yin XL,Zhao ZW,Zhou YA

    更新日期:2020-03-01 00:00:00

  • Management of acute postoperative pain with continuous intercostal nerve block after single port video-assisted thoracoscopic anatomic resection.

    abstract:BACKGROUND:Effective postoperative pain control for thoracic surgery is very important, not only because it reduces pulmonary complications but also because it accelerates the pace of recovery. Moreover, it increases patients' satisfaction with the surgery. In this study, we present a simple approach involving the safe...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.12.30

    authors: Hsieh MJ,Wang KC,Liu HP,Gonzalez-Rivas D,Wu CY,Liu YH,Wu YC,Chao YK,Wu CF

    更新日期:2016-12-01 00:00:00

  • Prosthetic valve endocarditis after transcatheter aortic valve implantation-diagnostic and surgical considerations.

    abstract::Prosthetic valve endocarditis (PVE) after transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (SAVR) is a potential life threatening complication. Better understanding of the incidence, predictors, clinical presentation, diagnostic measures, complications and management of PVE may help ...

    journal_title:Journal of thoracic disease

    pub_type:

    doi:10.21037/jtd.2016.10.28

    authors: Ahmad K,Klaaborg KE,Hjortdal V,Nørgaard BL,Terkelsen CJ,Jensen K,Christiansen EH,Terp KA,Andersen G,Hvitfeldt S,Andersen HR

    更新日期:2016-10-01 00:00:00

  • Uniportal video-assisted thoracic surgery right upper lobectomy with systemic lymphadenectomy.

    abstract::This video demonstrated a performance of uniportal video-assisted thoracoscopic surgery (VATS) right upper lobectomy with systemic lymphadenectomy. The patient had a malignant mass in his right upper lobe. The operator took a posterior to anterior approach to dissection the right upper lobe, the adjacent structures we...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.05.01

    authors: Han DP,Xiang J,Li HC,Hang JB

    更新日期:2016-08-01 00:00:00

  • How well does pathologic stage predict survival for esophageal adenocarcinoma after neoadjuvant therapy?

    abstract:BACKGROUND:Cancer staging systems are designed to predict survival and stratify patients. The 7(th) edition of the American Joint Commission on Cancer (AJCC7) staging system for esophageal cancer was modeled using survival data on patients who underwent esophagectomy without induction or adjuvant therapy. In the United...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2015.04.30

    authors: Kim JY,Nelson RA,Kim J,Raz D

    更新日期:2015-04-01 00:00:00

  • Role of electromagnetic navigational bronchoscopy in pulmonary nodule management.

    abstract::The incidence of pulmonary nodules and lung cancer is rising. Some of this increase in incidence is due to improved pick up by newer imaging modalities. However, the goal is to diagnose these lesion, many of which are located in the periphery, by safe and relatively non-invasive methods. This has led to the emergence ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.21037/jtd.2016.02.73

    authors: Goud A,Dahagam C,Breen DP,Sarkar S

    更新日期:2016-07-01 00:00:00