Sequencing postoperative radiotherapy and adjuvant chemotherapy in non-small cell lung cancer: unanswered questions on the not evidence-based approach.

abstract：:[This corrects the article DOI: 10.21037/jtd.2017.10.107.]. ...

journal_title：Journal of thoracic disease

authors： Wang K,Xi W,Yang D,Zheng Y,Zhang Y,Chen Y,Yan C,Tian G,An S,Li X,An F,Du J,Hu K,Cao J,Ren L,Huang F,Gao Z

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:Double lung point is a rare sign of pneumothorax in clinical practice. In this report I presented an 18-month-old child who presented with bilateral pneumothorax. DATA SYNTHESIS AND CASE PRESENTATION:Ultrasonography examination revealed conventional lung point sign on the right and double lung point on the l...

journal_title：Journal of thoracic disease

authors： Zhang Z

更新日期：2015-03-01 00:00:00

abstract：:Preoperative patient optimisation is a key point of enhanced recovery after thoracic surgery pathways. This could be particularly advantageous when considering video-assisted thoracic surgery (VATS) lobectomy, because reduced trauma related to minimally invasive techniques is one of the main factors favouring improved...

journal_title：Journal of thoracic disease

authors： D'Andrilli A,Massullo D,Rendina EA

更新日期：2018-03-01 00:00:00

abstract：Background:For malignant pleural mesothelioma (MPM), the benefit of resection, as well as the optimal surgical technique, remain controversial. In efforts to better refine patient selection, this retrospective observational cohort study queried the National Cancer Database in an effort to quantify and evaluate predicto...

journal_title：Journal of thoracic disease

authors： Wright C,Verma V,Barsky AR,Haque W,Polamraju PV,Ludmir EB,Zaorsky NG,Lehrer EJ,Trifiletti DM,Grover S,Friedberg JS,Simone CB 2nd

更新日期：2020-11-01 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) is a uniformly fatal disease and most patients will present with advanced stage. Treatment outcomes remain unsatisfactory, with low long-term survival rates. Standard treatment, such as palliative chemotherapy and radiotherapy, offers a median survival not exceeding 1 year. Hence, co...

journal_title：Journal of thoracic disease

authors： Méndez M,Custodio A,Provencio M

更新日期：2011-03-01 00:00:00

abstract：Background:Cervical anastomotic leakage remains a great challenge for thoracic surgeons in the surgical treatment of esophageal cancer. Among the factors affecting cervical anastomosis healing, the surgical technique is the key controllable element. This study aimed to identify the risk factors of cervical anastomotic ...

journal_title：Journal of thoracic disease

authors： Luo J,Zhuo ZG,Zhu YK,Deng HY,Song TN,Alai GH,Shen X,Lin YD

更新日期：2020-05-01 00:00:00

abstract：Background:To evaluate therapeutic efficacy of minimally invasive and small incision surgery [minimally invasive surgery (MIS)] in patients with non-flail chest rib fractures through a prospective cohort study. Methods:This study included 98 patients with non-flail chest rib fractures (≥3 displaced fractures) and 66 p...

journal_title：Journal of thoracic disease

authors： Li Y,Gao E,Yang Y,Gao Z,He W,Zhao Y,Wu W,Zhao T,Guo X

更新日期：2020-07-01 00:00:00

abstract：Background:Epidermal growth factor receptor (EGFR) is reportedly overexpressed in most esophageal tumors, but most targeted therapies showed no efficacy in non-selected patients. This study aims at investigating the adaptive cetuximab subset in a cohort of esophageal squamous cell carcinoma (ESCC) patient-derived xenog...

journal_title：Journal of thoracic disease

authors： Zhu H,Wang C,Wang J,Chen D,Deng J,Deng J,Fan J,Badakhshi H,Huang X,Zhang L,Cai J,Guo S,Qian W,Nie Y,Li Q,Zhao K

更新日期：2018-09-01 00:00:00

abstract：:Epiphrenic esophageal diverticulum is uncommon disease, which is defined as the herniation of the mucosa and submucosa through the muscle layers of the esophageal wall in distal third of the esophagus. Traditionally, thoracotomy has been the preferred surgical approach. Recently, many surgeons have attempted minimally...

journal_title：Journal of thoracic disease

authors： Kang DK

更新日期：2017-01-01 00:00:00

abstract：Background:Reconstruction of the aorto-mitral curtain (AMC) for invasive double-valve infective endocarditis (IE) is a rare and challenging procedure. This study presents the short- and mid-term results of reconstruction of AMC in a single center. Methods:From 2016 to 2019, 14 patients with invasive double-valve under...

journal_title：Journal of thoracic disease

authors： Jiang X,Liu J,Khan F,Tang R,Zhang Y,Gu T

更新日期：2020-04-01 00:00:00

abstract：:The intrathoracic (or substernal) goiter is more often benign; but it can be malignant in 2-22% of patients. There is history of prior thyroid surgery in 10% to more than 30% of patients. Intrathoracic goiters cause adjacent structure compression more frequently than the cervical goiters, due to the limited space of t...

journal_title：Journal of thoracic disease

authors： Tsakiridis K,Visouli AN,Zarogoulidis P,Karapantzos E,Mpakas A,Machairiotis N,Stylianaki A,Christofis C,Katsikogiannis N,Courcoutsakis N,Zarogoulidis K

更新日期：2012-11-01 00:00:00

abstract：:Primitive neuro-ectodermal tumour of the lung is an extremely rare occurrence and we hereby report a case of a neuro-ectodermal tumour of the lung which was proved by immuno-histochemical examination of the resected specimen, and he had a very aggressive pattern of behavior. ...

journal_title：Journal of thoracic disease

authors： Gaude GS,Patil P,Malur P,Annurshetru S

更新日期：2015-12-01 00:00:00

abstract：:Pulmonary embolism (PE) by occlusion of the pulmonary arterial bed may lead to acute life-threatening but potentially reversible right ventricular failure, one of the most severe complications of thoracic surgery. Still, the incidence of acute pulmonary embolism after surgery is reduced by comprehensive anticoagulant ...

journal_title：Journal of thoracic disease

authors： Wang Z,Pei C,Ma L,Wang D,Zhou J,Wang W,Shen J,Xu Z,He J

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:There is increasing evidence that a considerable proportion of patients with diabetes remain undiagnosed and untreated, however, it is unclear whether this is associated with more severe coronary artery disease (CAD) and microvasculature changes compared with diagnosed patients. We assessed CAD extent and se...

journal_title：Journal of thoracic disease

authors： Phan K,Mitchell P,Liew G,Plant AJ,Wang SB,Xu J,Chiha J,Thiagalingam A,Burlutsky G,Gopinath B

更新日期：2016-07-01 00:00:00

abstract：Background:To investigate the epidemiological characteristics of 11 atypical pathogens of community-acquired pneumonia (CAP) among Chinese, and to determine whether or not there is an association between these pathogens and the severity of illness. Methods:We conducted a surveillance study for CAP in 30 hospitals of B...

journal_title：Journal of thoracic disease

authors： Gong C,Zhang T,Luo M,Li A,Dong M,Li M,Wang Y,Huang F

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The characteristics of patients with urinothorax (UT) are poorly defined. METHODS:A systematic review was performed searching for studies reporting clinical findings, pleural fluid (PF) characteristics, and the most effective treatment of UT. Case descriptions and retrospective studies were included. RESUL...

journal_title：Journal of thoracic disease

authors： Toubes ME,Lama A,Ferreiro L,Golpe A,Álvarez-Dobaño JM,González-Barcala FJ,San José E,Rodríguez-Núñez N,Rábade C,Lourido T,Valdés L

更新日期：2017-05-01 00:00:00

abstract：Background:High levels of thymidylate synthase (TS) and dihydrofolate reductase (DHFR) expression in tumour tissues are an indicator of ineffective responses to pemetrexed-based chemotherapy in various tumours, including non-small cell lung cancer (NSCLC). However, tumour tissues are highly heterogeneous, so a single b...

journal_title：Journal of thoracic disease

authors： Li T,Huang JB,Lu JG,Li R,Wang Y,Shi XR,Shi MX,Zhang XD

更新日期：2020-12-01 00:00:00

abstract：:Video-assisted thoracoscopic surgery (VATS) is a type of thoracic surgery performed using a small video camera that is introduced into the patient's chest via a scope. It is considered a minimally invasive technique where the surgeon is able to view the instruments that are being used along with the anatomy on which t...

journal_title：Journal of thoracic disease

authors： Paliouras D,Barbetakis N,Lazaridis G,Baka S,Mpoukovinas I,Karavasilis V,Kioumis I,Pitsiou G,Papaiwannou A,Karavergou A,Lampaki S,Katsikogiannis N,Mpakas A,Tsakiridis K,Korantzis I,Fassiadis N,Zarogoulidis K,Zarogoulidis

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Although N-ERC/mesothelin (N-ERC) is an attractive diagnostic and treatment monitoring biomarker for malignant pleural mesothelioma (MPM), its clinical utility for predicting the prognosis has not yet been clarified. The aim of this study is to investigate whether the serum N-ERC level can accurately predict...

journal_title：Journal of thoracic disease

authors： Mori T,Tajima K,Hirama M,Sato T,Kido K,Iwakami S,Sasaki S,Iwase A,Shiomi K,Maeda M,Hino O,Takahashi K

更新日期：2013-04-01 00:00:00

abstract：:Since its inception, minimally invasive surgery has made a dramatic impact on all branches of surgery. Video-assisted thoracic surgery (VATS) lobectomy for early-stage non-small cell lung cancer (NSCLC) was first described in the early 1990s and has since become popular in a number of tertiary referral centers. Propon...

journal_title：Journal of thoracic disease

authors： Cao CQ,Stine ML,Yan TD

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Lung cancer is a leading cause of death worldwide. Considerable studies have reported that NADPH oxidase (NOX) expression or activity may play an important role in the tumorigenesis of lung cancer. However, the results are inconsistent. Thus, a systematic review and meta-analysis were conducted in this study...

journal_title：Journal of thoracic disease

authors： Han M,Zhang T,Yang L,Wang Z,Ruan J,Chang X

更新日期：2016-07-01 00:00:00

abstract：:Diabetes mellitus (DM) and small vessel (SV) disease are two major predictors of adverse outcome in patients treated by percutaneous coronary intervention (PCI), even when last generation metallic drug-eluting stents (DES) are used. Bioresorbable scaffold (BRS) technology has been recently developed to overcome the di...

journal_title：Journal of thoracic disease

authors： Masiero G,Mojoli M,Ueshima D,Tarantini G

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:(18)F-FDG PET/CT is increasingly used in evaluation of treatment response for patients with non-small cell lung cancer (NSCLC). There is a need for an accurate criterion to evaluate the effect and predict the prognosis. The aim of this study is to evaluate therapeutic response in NSCLC with comparing PET res...

journal_title：Journal of thoracic disease

authors： Ding Q,Cheng X,Yang L,Zhang Q,Chen J,Li T,Shi H

更新日期：2014-06-01 00:00:00

abstract：:The last decade has seen significant advances in our understanding of lung cancer biology and management. Identification of key driver events in lung carcinogenesis has contributed to the development of targeted lung cancer therapies, heralding the era of personalised medicine for lung cancer. As a result, histologica...

journal_title：Journal of thoracic disease

authors： Davidson MR,Gazdar AF,Clarke BE

更新日期：2013-10-01 00:00:00

abstract：:Many patients who require lung resection have cardiovascular and cerebrovascular comorbidities. It has been recommended that surgical aortic valve replacement (SAVR) should precede lung resection in patients with severe aortic valve stenosis (AS). However, by first undergoing transcatheter aortic valve implantation (T...

journal_title：Journal of thoracic disease

authors： Sakai T,Yahagi K,Miura S,Hoshino T,Yokota T,Tanabe K,Ikeda S

更新日期：2018-05-01 00:00:00

abstract：Background:CO2 insufflation could provide a better surgical field during single-incision thoracoscopic surgery (SITS) with small tidal two-lung ventilation (ST-TLV). Here we compared the surgical field and physiological effects of ST-TLV with and without CO2 during SITS. Methods:Patients underwent scheduled SITS bulle...

journal_title：Journal of thoracic disease

authors： Lee DK,Kim H,Kim HK,Chung DI,Han KN,Choi YH

更新日期：2018-08-01 00:00:00

abstract：Background:Calcific aortic valve disease (CAVD) is the most common type of valvular heart disease in the elderly. This study is aimed to explore molecular mechanism of CAVD via bioinformatics analysis. Methods:The gene expression profiles of GSE51472 (including 5 normal aortic valve and 5 calcified aortic valve) and G...

journal_title：Journal of thoracic disease

authors： Zhang Y,Ma L

更新日期：2019-12-01 00:00:00

abstract：:Chronic dyspnoea, or breathlessness for more than four weeks duration, is a common symptom in adults presenting to primary and tertiary care. It often presents a diagnostic challenge due to the wide spectrum of underlying disease, which is multifactorial in approximately one third of cases. Challenges in diagnosis inc...

journal_title：Journal of thoracic disease

authors： Ferry OR,Huang YC,Masel PJ,Hamilton M,Fong KM,Bowman RV,McKenzie SC,Yang IA

更新日期：2019-10-01 00:00:00

abstract：:Lung cancer continues to be the leading cause of cancer death worldwide. Recently, immunotherapy for non-small cell lung cancer (NSCLC) has emerged as a powerful treatment option for advanced lung cancer. The relative success of programmed death 1 (PD-1) and/or programmed death ligand 1 (PD-L1) antibodies in metastati...

journal_title：Journal of thoracic disease

authors： Yeh J,Marrone KA,Forde PM

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:According to the present evidences suggesting association between low testosterone level and prediction of reduced exercise capacity as well as poor clinical outcome in patients with heart failure, we sought to determine if testosterone replacement therapy (TRT) improves clinical and cardiovascular condition...

journal_title：Journal of thoracic disease

authors： Wang W,Jiang T,Li C,Chen J,Cao K,Qi LW,Li P,Zhu W,Zhu B,Chen Y

更新日期：2016-05-01 00:00:00