New molecular targeted therapies for advanced non-small-cell lung cancer.

abstract：Background:Complete resection is the mainstay of treatment for thymoma, but few studies have investigated the extent of resection on normal thymus. Extended thymectomy is considered the treatment of choice for myasthenic patients with thymoma, while the optimal therapy for non-myasthenic patients is still a matter of d...

journal_title：Journal of thoracic disease

authors： Tassi V,Ceccarelli S,Zannori C,Gili A,Daddi N,Bellezza G,Ascani S,Liberati AM,Puma F

更新日期：2017-10-01 00:00:00

abstract：Background:Pacing parameters may influence pacing lead life and pacemaker life. This study sought to determine whether different right atrial active-fixation lead implantation parameters are associated with chronic pacing performance. Methods:A retrospective observational study was conducted on all consecutive patient...

journal_title：Journal of thoracic disease

authors： Chen MR,Zhang FL,Wang WW,Chen XH,Chen JH,Chen LL

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:A clinical trial of extracorporeal membrane oxygenation (ECMO) as an alternative ventilator tool is being performed as a new indication for ECMO. The purpose of this study was to evaluate the feasibility of awake ECMO to increase the success rate of weaning patients from ECMO and ventilator care during treat...

journal_title：Journal of thoracic disease

authors： Yeo HJ,Cho WH,Kim D

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The feasibility and practicality of preoperative rehabilitation (PR) programs remains quite controversial in the treatment of lung cancer (LC). This study explored whether a short-term high-intensity rehabilitation program could improve postoperative outcomes compared to those achieved with conventional insp...

journal_title：Journal of thoracic disease

authors： Huang J,Lai Y,Zhou X,Li S,Su J,Yang M,Che G

更新日期：2017-07-01 00:00:00

abstract：Background:Persistent cardiac hypertrophy threatens health worldwide. Long non-coding RNAs (lncRNAs) attracted lots of attention in cardiac diseases such as cardiac hypertrophy. In this study, we aimed to study the function of KCNQ1OT1 in cardiac hypertrophy. Methods:We first used qRT-PCR to detect the expression of K...

journal_title：Journal of thoracic disease

authors： Chen Y,Zhang Z,Zhu D,Zhao W,Li F

更新日期：2020-09-01 00:00:00

abstract：Background:Arterial desaturations experienced during endotracheal intubation (ETI) may lead to poor outcomes. Thus, our primary aim was to identify predictors of arterial desaturation (pulse oximetry <90%) during the peri-intubation period and to assess outcomes of those who developed arterial hypoxemia. Methods:Adult...

journal_title：Journal of thoracic disease

authors： Smischney NJ,Seisa MO,Heise KJ,Wiegand RA,Busack KD,Loftsgard TO,Schroeder DR,Diedrich DA

更新日期：2017-10-01 00:00:00

abstract：:Fatal hemoptysis is a serious complication of pulmonary tuberculosis, which can rarely be due to a bronchial aneurysm. Here, we present a case of fatal hemoptysis due to bronchial aneurysm occurred in a 59-year-old patient of Han ethnicity suffering from active pulmonary tuberculosis. Meanwhile, we perform a literatur...

journal_title：Journal of thoracic disease

authors： Cheng YS,Lu ZW

更新日期：2014-06-01 00:00:00

abstract：:Video-assisted thoracoscopic surgery (VATS) segmentectomy is a promising treatment option for rigorously selected patients with earlystage non-small cell lung cancer. In the presented video, a 66-year-old male with a 1.6 cm suspicious nodule located at the posterior segment of the right upper lobe was treated with ana...

journal_title：Journal of thoracic disease

authors： Ma L,Liu C,Liu L

更新日期：2014-12-01 00:00:00

abstract：Background:To investigate the roles of gastrin-releasing peptide (ProGRP) in the diagnosis of small cell lung cancer (SCLC). Methods:We retrospectively analyzed data from 11,206 patients with clinical suspicion of lung cancer from January 1, 2015 to May 31, 2018. ProGRP and neuron-specific enolase (NSE) were detected ...

journal_title：Journal of thoracic disease

authors： Dong A,Zhang J,Chen X,Ren X,Zhang X

更新日期：2019-04-01 00:00:00

abstract：:Cardiopulmonary support is frequently required during lung transplantation. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has been recently shown to be an acceptable and, perhaps, safer alternative to cardiopulmonary bypass machine (CBM) for lung transplantation. However, therapeutic anticoagulation used...

journal_title：Journal of thoracic disease

authors： Bharat A,DeCamp MM

更新日期：2017-07-01 00:00:00

abstract：:Recent studies have demonstrated that there are differences among races in efficacy, tolerance and other outcomes in oncologic care. Some of these differences may be explained by different pharmacogenetics; however, social and environmental factors that can affect oncology practice are relatively underestimated. In th...

journal_title：Journal of thoracic disease

authors： Komiya T,Chaaya G,Deshotels L,Wang A

更新日期：2020-07-01 00:00:00

abstract：:In functionally fit patients with localized disease surgical resection remains the treatment of choice. There is also good evidence to support the use of chemotherapy in stages II-III. However, whether to use neoadjuvant or adjuvant therapy has been the topic of much debate. With its strong evidence base, adjuvant che...

journal_title：Journal of thoracic disease

authors： McElnay P,Lim E

更新日期：2014-05-01 00:00:00

abstract：:The cornerstone of curative care for esophageal cancer is neoadjuvant chemoradiotherapy followed by esophagectomy with a radical lymphadenectomy. An esophagectomy is a major and complex surgical procedure and is often followed by postoperative morbidity, especially pulmonary complications. These complications may lead...

journal_title：Journal of thoracic disease

authors： Seesing MFJ,Kingma BF,Weijs TJ,Ruurda JP,van Hillegersberg R

更新日期：2019-04-01 00:00:00

abstract：:Lung transplantation is the only therapeutic option for end-stage pulmonary failure. Nevertheless, the shortage of donor pool available for transplantation does not allow to satisfy the requests, thus the mortality on the waiting list remains high. One of the tools to overcome the donor pool shortage is the use of ex-...

journal_title：Journal of thoracic disease

authors： Rosso L,Zanella A,Righi I,Barilani M,Lazzari L,Scotti E,Gori F,Mendogni P

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Studies on diagnostic tests for exercise-induced bronchoconstriction (EIB) have centered around the asthmatic and elite athletic population. Traditionally, the exercise challenge test (ET) was recommended to assess EIB. We aimed to compare the performance of surrogate testing, mainly the hypertonic saline (H...

journal_title：Journal of thoracic disease

authors： Tan JHY,Chew WM,Lapperre TS,Tan GL,Loo CM,Koh MS

更新日期：2017-03-01 00:00:00

abstract：:Esophagectomy is a complex surgical procedure associated with high rates of mortality and morbidity, mainly dominated by pulmonary complications. Minimally invasive approaches have been developed in order to decrease postoperative morbidity, including totally minimally invasive esophagectomy (MIE) and hybrid esophagec...

journal_title：Journal of thoracic disease

authors： Voron T,Lintis A,Piessen G

更新日期：2019-04-01 00:00:00

abstract：Background:Cervical anastomotic leakage remains a great challenge for thoracic surgeons in the surgical treatment of esophageal cancer. Among the factors affecting cervical anastomosis healing, the surgical technique is the key controllable element. This study aimed to identify the risk factors of cervical anastomotic ...

journal_title：Journal of thoracic disease

authors： Luo J,Zhuo ZG,Zhu YK,Deng HY,Song TN,Alai GH,Shen X,Lin YD

更新日期：2020-05-01 00:00:00

abstract：Background:In veno-arterial extracorporeal membrane oxygenation (V-A ECMO), a patient is cannulated using either an atrio-aortic technique (central type ECMO; cECMO) or a femoro-femoral technique (peripheral type ECMO; pECMO). The direction of the pump flow at the aortic arch is anterograde from the ascending aorta in ...

journal_title：Journal of thoracic disease

authors： Jeong SC,Kim HJ,Shin YS,Han JW,Lim JY,Son HS

更新日期：2018-11-01 00:00:00

abstract：:Performing dual point 18F-FDG PET scans of solitary pulmonary nodules at an initial SUV (max) <2.5 is a useful technique. However, prolonging second image acquisition from 120 to 180 min does not appear to improve accuracy. Dual time 18F-FDG PET is not useful in differentiating benign and malignant pulmonary nodules w...

journal_title：Journal of thoracic disease

authors： Khan AN,Al-Jahdali H

更新日期：2013-06-01 00:00:00

abstract：Background:Continuous positive airway pressure (CPAP), the best available treatment for obstructive sleep apnea (OSA), requires long-term compliance to be effective. Behavioral interventions may be used to improve adherence to CPAP. We aimed to investigate whether positive or negative message framing impacts on CPAP co...

journal_title：Journal of thoracic disease

authors： Pengo MF,Czaban M,Berry MP,Nirmalan P,Brown R,Birdseye A,Woroszyl A,Chapman J,Kent BD,Hart N,Rossi GP,Steier J

更新日期：2018-01-01 00:00:00

abstract：Background:Eosinophilic chronic obstructive pulmonary disease (COPD) patients have eosinophilic airway inflammation. No prospective study has reported blood eosinophil counts in an endemic area for parasitic infection. The primary objective was to compare exacerbation rates. The secondary objectives were patient-report...

journal_title：Journal of thoracic disease

authors： Juthong S,Kaenmuang P

更新日期：2020-09-01 00:00:00

abstract：:Tuberculosis (TB) is still a major public health concern, mostly affecting resource-constrained settings and marginalized populations. The fight against the disease is hindered by the growing emergence of drug-resistant forms whose management can be rather challenging. Surgery may play an important role to support dia...

journal_title：Journal of thoracic disease

authors： Subotic D,Yablonskiy P,Sulis G,Cordos I,Petrov D,Centis R,D'Ambrosio L,Sotgiu G,Migliori GB

更新日期：2016-07-01 00:00:00

abstract：Background:Operative safety and oncologic adequacy of thoracoscopic sleeve lobectomy remain controversial. As such, the purpose of this meta-analysis was to evaluate evidence comparing thoracoscopy and thoracotomy in sleeve lobectomy for centrally located non-small cell lung cancer (NSCLC). Methods:Electronic searches...

journal_title：Journal of thoracic disease

authors： Zhong Y,Wang Y,Hu X,Wang G,She Y,Deng J,Zhang L,Peng Q,Zhu Y,Jiang G,Yang M,Xie D,Chen C

更新日期：2020-10-01 00:00:00

abstract：:In this case, a patient presented with a large primary midtracheal tumor posterior to the innominate vein and brachiocephalic artery. The left innominate vein (LIV) was temporarily transected to attain proper access to the tumor. After complete removal of the tumor, the vessel was reanastomosed. The operation was unev...

journal_title：Journal of thoracic disease

authors： Ren F,Pu Q,Liu L

更新日期：2014-02-01 00:00:00

abstract：:Congenital pulmonary agenesis is a rare condition with high mortality. Mechanical ventilation in these patients is challenging and there has no such case been reported in the literature. We reported a 61-year-old female with lung agenesis who presented to our hospital with pneumonia and pelvic mass. In the past, she h...

journal_title：Journal of thoracic disease

authors： Yu Y,Zhu C,Qian X,Gao Y,Zhang Z

更新日期：2016-01-01 00:00:00

abstract：:The expanded possibilities to explore the lung deeper with new tools such as electromagnetic navigation bronchoscopy (ENB) or radial probe endobronchial ultrasonography (radial EBUS), combined with miniaturization of traditional local therapies such as radiofrequency ablation (RFA), radiotherapy, cryotherapy or photod...

journal_title：Journal of thoracic disease

authors： Vieira T,Stern JB,Girard P,Caliandro R

更新日期：2018-04-01 00:00:00

abstract：Background:Cigarette smoking remains a significant public health problem. However, current treatment programs have not yet succeeded in sufficiently reducing smoking rates. The study aimed to examine whether patients' recognition of "spirometric-lung-age (SLA)" estimated from spirometry data prompts smoking cessation. ...

journal_title：Journal of thoracic disease

authors： Takagi H,Morio Y,Ishiwata T,Shimada K,Kume A,Miura K,Kuwasaki E,Kato M,Seyama K,Takahashi K

更新日期：2017-12-01 00:00:00

abstract：:Optimal exposure of the mitral valve is paramount in minimally invasive surgery (MIS) and a prerequisite for successful mitral valve repair or replacement. We report the concept of a new left atrial retractor (Karl Storz GmbH, Tuttlingen, Germany) dedicated to MIS. The effectiveness of the device was evaluated in a pr...

journal_title：Journal of thoracic disease

authors： Greco E,Rose D,Irace F,Frati G

更新日期：2016-12-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) associates with several extra-pulmonary effects. Muscle dysfunction and wasting is one of the most prominent extra-pulmonary effects and contributes to exercise limitation and health related quality of life (HRQoL), morbidity as well as mortality. The loss of muscle mass is...

journal_title：Journal of thoracic disease

authors： Lakhdar R,Rabinovich RA

更新日期：2018-05-01 00:00:00

abstract：:Lung transplantation is the gold standard therapy for patients with end-stage lung disease. The use of the lung allocation score (LAS) has permitted improved allocation of scarce pulmonary allografts. Recently, Crawford et al. examined the experience in the United States in lung transplantation in candidates with the ...

journal_title：Journal of thoracic disease

authors： Mulvihill MS,Hartwig MG,Daneshmand MA

更新日期：2017-09-01 00:00:00