Surgery and pleuro-pulmonary tuberculosis: a scientific literature review.

Abstract:

:Tuberculosis (TB) is still a major public health concern, mostly affecting resource-constrained settings and marginalized populations. The fight against the disease is hindered by the growing emergence of drug-resistant forms whose management can be rather challenging. Surgery may play an important role to support diagnosis and treatment of the most complex cases and improve their therapeutic outcome. We conducted a non-systematic review of the literature based on relevant keywords through PubMed database. Papers in English and Russian were included. The search was focused on five main areas of intervention as follows: (I) diagnosis of complicated cases; (II) elimination of contagious persisting cavities, despite appropriate chemotherapy; (III) treatment of destroyed lung; (V) resection of tuberculomas; (VI) treatment of tuberculous pleural empyema. Although specific practical guidelines concerning surgical indications and approaches are currently unavailable, a summary of the evidence emerged from the scientific literature was elaborated to help the clinician in the management of severely compromised TB patients. The decision to proceed to surgery is usually individualized and a careful assessment of the patient's risk profile is always recommended before performing any procedure in addition to appropriate chemotherapy.

journal_name

J Thorac Dis

authors

Subotic D,Yablonskiy P,Sulis G,Cordos I,Petrov D,Centis R,D'Ambrosio L,Sotgiu G,Migliori GB

doi

10.21037/jtd.2016.05.59

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

E474-85

issue

7

eissn

2072-1439

issn

2077-6624

pii

jtd-08-07-E474

journal_volume

8

pub_type

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