Principles and indications of extracorporeal life support in general thoracic surgery.


:The role of extracorporeal life support (ECLS) has expanded rapidly over the past 15 years to become an important tool in advanced general thoracic surgery practice. Intra-operative and in some cases continued post-operative ECLS is redefining the scope of complex surgical care. ECLS encompasses a spectrum of temporary mechanical support that may remove CO2, oxygenate or provide hemodynamic support or a combination thereof. The most common modalities used in general thoracic surgery include extracorporeal membrane oxygenation (ECMO), interventional lung assist device (iLA® Novalung®, Heilbronn, Germany), and extracorporeal CO2 removal (ECCO2R). The ECMO and Novalung® devices can be used in different modes for the short term or long-term support depending on the situation. In this review, the principles and current applications of ECLS in general thoracic surgery are presented.


J Thorac Dis


McRae K,de Perrot M




Has Abstract


2018-04-01 00:00:00




Suppl 8










  • Results of neoadjuvant therapy followed by esophagectomy for patients with locally advanced thoracic esophageal squamous cell carcinoma.

    abstract:BACKGROUND:For patients diagnosed with locally advanced esophageal cancer, neoadjuvant therapy followed by surgery is the most common approach. However, randomized trials resulted in inconsistent conclusions. We conducted this retrospective study to evaluate the influence of neoadjuvant therapy on postoperative events ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Lin D,Ma L,Ye T,Pan Y,Shao L,Song Z,Jiang S,Chen H,Xiang J

    更新日期:2017-02-01 00:00:00

  • Acute pulmonary embolism after pneumonectomy.

    abstract::Pulmonary embolism (PE) by occlusion of the pulmonary arterial bed may lead to acute life-threatening but potentially reversible right ventricular failure, one of the most severe complications of thoracic surgery. Still, the incidence of acute pulmonary embolism after surgery is reduced by comprehensive anticoagulant ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Wang Z,Pei C,Ma L,Wang D,Zhou J,Wang W,Shen J,Xu Z,He J

    更新日期:2012-02-01 00:00:00

  • Circ_0058063 upregulates GLUT1 expression and promotes glucose-uptake in esophageal squamous-cell carcinomas.

    abstract:Background:CirRNA Circ_0058063 has been proven as an oncogene in bladder cancer, while its involvement in esophageal squamous-cell carcinomas (ESCC) is unknown. This study aimed to investigate the role of Circ_0058063 in ESCC. Methods:Paired ESCC and non-tumor tissues were collected from ESCC patients and gene express...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Zheng Y,Chen Y,Jiang H,Zhang H,Wang H,Xu J,Yu Z

    更新日期:2020-03-01 00:00:00

  • Pleural fluid glucose testing using a finger stick glucometer: a novel bedside test.

    abstract:Background:Pleural fluid glucose (PFG) has diagnostic and therapeutic implications for the management of pleural effusion. The literature examining point-of-care testing of PFG is limited, and no studies exist for the bedside measurement of PFG using a glucometer (B-PFG). In this study, we compared the accuracy of B-PF...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Abdo TF,Bhardwaj H,Ishaq MK,Keddissi JI,Youness HA

    更新日期:2019-11-01 00:00:00

  • Six minute walking test and carbon monoxide diffusing capacity for non-small cell lung cancer: easy performed tests in every day practice.

    abstract:BACKGROUND:Several studies have demonstrated that reduced lung function is a significant risk factor for lung cancer and increased surgical risk in patients with operable stages of lung cancer. The aim of the study was to perform pulmonary function tests and investigate which is a favorable respiratory function test fo...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Zarogoulidis P,Kerenidi T,Huang H,Kontakiotis T,Tremma O,Porpodis K,Kalianos A,Rapti A,Foroulis C,Zissimopoulos A,Courcoutsakis N,Zarogoulidis K

    更新日期:2012-12-01 00:00:00

  • Patient safety in thoracic surgery and European Society of Thoracic Surgeons checklist.

    abstract::Improving patient safety seems to be a new interesting clinical subject but, in fact, it is no new. It has to do with one of the oldest ethical principles of our profession: curing and not harming. The important research that has been done in a short period of time has brought in new insight to this complex area that ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审


    authors: Novoa NM

    更新日期:2015-04-01 00:00:00

  • Five-year outcomes after thoracic endovascular aortic repair of symptomatic type B penetrating aortic ulcer with intramural hematoma in Chinese patients.

    abstract:Background:The aim of this study is to evaluate the five-year outcomes after thoracic endovascular aortic repair (TEVAR) of symptomatic Stanford type B penetrating aortic ulcer (PAU) associated with intramural hematoma (IMH) in Chinese patients. Methods:From January 2009 to April 2013, 118 patients with typical severe...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Liu J,Liu Y,Yang W,Gu J,Xue S

    更新日期:2019-01-01 00:00:00

  • Levels of 1,25(OH)2D3 for patients with pulmonary tuberculosis and correlations of 1,25(OH)2D3 with the clinical features of TB.

    abstract:BACKGROUND:To determine the 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] concentrations to patients with tuberculosis (TB) and whether it influenced the patient's clinical features. METHODS:For the first part, a total of 153 healthy adults and 74 patients with pulmonary TB (PTB) were enrolled. Serum concentrations of 1,25(O...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Gao WW,Wang Y,Zhang XR,Yin CY,Hu CM,Tian M,Wang HW,Zhang X

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  • Vitamin C alone does not improve treatment outcomes in mechanically ventilated patients with severe sepsis or septic shock: a retrospective cohort study.

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    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Ahn JH,Oh DK,Huh JW,Lim CM,Koh Y,Hong SB

    更新日期:2019-04-01 00:00:00

  • Novel air leak test using surfactant for lung surgery.

    abstract:Background:Prolonged air leak is the most common complication after pulmonary resection surgery. Water submersion test (WST) has been used to check for air leak. However, it is cumbersome under the circumstances of video-assisted thoracic surgery (VATS). This study aimed to devise a new air leak detection method that i...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Yang HC,Chang HY

    更新日期:2018-12-01 00:00:00

  • To avoid compensatory hyperhidrosis after sympathetic surgery for craniofacial hyperhidrosis.

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    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Moon DH,Kang DY,Lee HS,Lee JW,Lee YJ,Lee S

    更新日期:2020-05-01 00:00:00

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    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审


    authors: Filosso PL,Falcoz PE,Solidoro P,Pellicano D,Passani S,Guerrera F,Ruffini E,ESTS Lung Neuroendocrine Working-Group Participating Centers*.

    更新日期:2018-10-01 00:00:00

  • Carinal resection and sleeve pneumonectomy.

    abstract::Carinal resection (CR) and sleeve pneumonectomy (SP) are one of the challenging issues in thoracic surgery and performed rarely. In spite of the knowledge of the technique, the incidence of postoperative complications is higher compared to standard resections. Adequate patient selection, improved anesthetic management...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审


    authors: Weder W,Inci I

    更新日期:2016-11-01 00:00:00

  • Prognostic significance of IMP-3 expression pattern in esophageal squamous cell carcinoma.

    abstract:Background:Esophageal cancer is one of the most malignant gastroenterological cancers. To improve the treatment outcomes of patients with esophageal squamous cell carcinoma (ESCC), a biomarker capable of predicting the malignant potential of the cancer cells is needed. The aim of the present study was to investigate th...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Sakakibara T,Ozawa S,Oguma J,Nakui M,Yamamoto S,Makuuchi H,Kajiwara H,Nakamura N

    更新日期:2019-09-01 00:00:00

  • Postoperative changes of the free pericardial fat pad for bronchial stump coverage.

    abstract:Background:Bronchopleural fistula (BPF) remains a serious complication after surgery for lung cancer with bronchial resection. A free pericardial fat pad (FPFP) is applied in high-risk cases to reduce BPF frequency. BPF may occur 6 months after surgery. Thus, we evaluated the residual FPFP volume at 6 months after surg...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Nagashima T,Ito H,Samejima J,Nemoto D,Eriguchi D,Nakayama H,Woo T,Masuda M

    更新日期:2019-12-01 00:00:00

  • Comparison of outcomes following isolated repair of tricuspid versus bicuspid aortic valves.

    abstract:Background:Aortic valve repair (AV-repair) is an alternative treatment option for patients with aortic regurgitation (AR), but durability is still reason for concern, especially for bicuspid aortic valves (BAV). We retrospectively evaluated mid-term results after AV-repair in patients with BAV or tricuspid aortic valve...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Prinzing A,Boehm J,Erlebach M,Sideris K,Lange R,Krane M

    更新日期:2020-07-01 00:00:00

  • Learning curve for robot-assisted lobectomy of lung cancer.

    abstract:Background:Robotic lobectomy is widely used for lung cancer treatment. So far, few studies have been performed to systematically analyze the learning curve. Our purpose is to define the learning curve to provide a training guideline of this technique. Methods:A total of 208 consecutive patients with primary lung cance...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Song G,Sun X,Miao S,Li S,Zhao Y,Xuan Y,Qiu T,Niu Z,Song J,Jiao W

    更新日期:2019-06-01 00:00:00

  • Do low profile implants provide reliable stability in fixing the sternal fractures as a "fourth vertebral column" in sternovertebral injuries?

    abstract:BACKGROUND:Flexion and compression forces to the trunk can cause severe instability of the vertebral column and the anterior chest wall, mostly associated with an unstable fracture of the sternum. In combination, the worst case would be a complete disruption of the trunk. Some authors consider the sternum-rib-complex t...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Krinner S,Grupp S,Oppel P,Langenbach A,Hennig FF,Schulz-Drost S

    更新日期:2017-04-01 00:00:00

  • Inframammary approach for addressing anterior mediastinal tumours: initial experience.

    abstract:Background:Anterior mediastinal tumours account for 50% of all mediastinal masses. Surgical intervention is the standard approach for their diagnosis or treatment. Minimally invasive techniques have gained significant popularity in the last few decades due to the obvious advantages that they offer. We will describe a s...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Ferreira R,Junqueira N,Rodrigues M,Nobre Â

    更新日期:2020-05-01 00:00:00

  • Single-port thoracoscopic right main bronchial tumor sleeve resection and secondary carinal reconstruction.

    abstract::We describe herein a case of single-port thoracoscopic right main bronchial tumor sleeve resection and secondary carinal reconstruction. A 66-year-old male patient had a right main bronchial tumor longer than 12 months, who had been received endobronchial cryosurgery twice before. However, the tumor relapsed quickly. ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Liang M,Chen C,Zheng W,Chen H,Wu W,Zhang S

    更新日期:2015-10-01 00:00:00

  • Left- and right-sided video-assisted thoracoscopic thymectomy exhibit similar effects on myasthenia gravis.

    abstract:BACKGROUND:Unilateral video-assisted thoracoscopic (VATS) thymectomy features less operative trauma, improved cosmesis, and similar efficiency compared with transsternal (TS) thymectomy for treatment of patients with myasthenia gravis (MG). Unilateral VATS thymectomy can be easily performed from either side of the thor...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Xie X,Gan X,Chen B,Shen Z,Wang M,Zhang H,Xu X,Chen J

    更新日期:2016-01-01 00:00:00

  • A case of malignant peritoneal mesothelioma revealed with limitation of PET-CT in the diagnosis of thoracic metastasis.

    abstract::A 47-year-old man was referred to our hospital because of a 2-month history of dry cough, 2-kg weight loss, and a feeling of abdominal fullness. The PET-CT scan depicts the intense standard uptake values (SUVs) of the anterior and subphrenic lymphnodes, and intraperitoneal cavity, especially in the omentum, while, no ...

    journal_title:Journal of thoracic disease



    authors: Saraya T,Yokoyama T,Ishii H,Tanaka Y,Tsujimoto N,Ogawa Y,Sohara E,Nakajima A,Inui T,Sayuki H,Fujiwara M,Oka T,Kawachi R,Goya T,Takizawa H,Goto H

    更新日期:2013-02-01 00:00:00

  • Clinicopathological analysis of 241 thymic epithelial tumors-experience in the Shanghai Chest Hospital from 1997-2004.

    abstract:BACKGROUND:To assess the correlation of WHO histological classification of thymomas and thymic carcinomas (TCs) with prognosis in recently treated patient cohort compared to a historical one from a single institution. METHODS:Retrospective review of clinical charts and histological sections of 241 patients treated dur...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Zhu L,Zhang J,Marx A,Weiss C,Fang WT

    更新日期:2016-04-01 00:00:00

  • Wide phenotypic variability in RSPH9-associated primary ciliary dyskinesia: review of a case-series from Cyprus.

    abstract:Background:Primary ciliary dyskinesia (PCD) is an inherited ciliary motility disorder caused by mutations in at least 40 genes. RSPH9 gene mutations encoding aberrant radial spoke head proteins have been linked with PCD. The clinical spectrum extent of RSPH9 gene mutations remains to date largely unknown. We aimed to d...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Yiallouros PK,Kouis P,Pirpa P,Michailidou K,Loizidou MA,Potamiti L,Kalyva M,Koutras G,Kyriacou K,Hadjisavvas A

    更新日期:2019-05-01 00:00:00

  • Sudden hypotension occurring after 4 days of left-sided central catheter placement.

    abstract::Central venous catheters (CVCs) have an important role in the management of critically ill patients. In contrast to the immediate complications after CVC insertion, the late complications were difficult to be noticed without high suspicion despite their life-threatening outcome. We report a rare but fatal delayed vasc...

    journal_title:Journal of thoracic disease



    authors: Kim YJ,Kim WY

    更新日期:2017-09-01 00:00:00

  • Deep sternal wound infection after cardiac surgery: a comparison of three different wound infection types and an analysis of antibiotic resistance.

    abstract:Background:Deep sternal wound infection (DSWI) is a severe complication following cardiac surgery. We compared epidemiology, clinical features, and microbiology of three types of DSWI and examined the antibiotic resistance in DSWI patients. Methods:From 2011 to 2015, 170 adult post-cardiac surgery DSWI patients were r...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Ma JG,An JX

    更新日期:2018-01-01 00:00:00

  • The diagnostic utility of endobronchial ultrasonography with a guide sheath and tomosynthesis images for ground glass opacity pulmonary lesions.

    abstract:BACKGROUND:With the widespread use of computed tomography (CT), the frequency of discovering ground glass opacity (GGO) pulmonary lesions has increased. There have been some reports on surgery or transthoracic needle aspiration (TTNA) for diagnostic sampling of GGOs but none on transbronchial biopsy (TBB). The purpose ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Izumo T,Sasada S,Chavez C,Tsuchida T

    更新日期:2013-12-01 00:00:00

  • A phase I dose escalation study of S-1 with concurrent radiotherapy in elderly patients with esophageal cancer.

    abstract:BACKGROUND:Concurrent chemoradiotherapy (CRT) with 5-fluorouracil (5-FU) and cisplatin (CDDP) are often associated with significant incidence of toxic effects in elderly patients with esophageal cancer. This phase I trial was designed to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of S-1...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Ji Y,Qiu G,Sheng L,Sun X,Zheng Y,Chen M,Du X

    更新日期:2016-03-01 00:00:00

  • Impact of attenuated plaques on TIMI grade flow and clinical outcomes of coronary artery disease patients: a systematic review and meta analysis.

    abstract:BACKGROUND:Plaques with a large necrotic core or lipid pool and thin-cap fibroatheroma manifest as attenuated plaques on intravascular ultrasound (IVUS). Their impact on TIMI grade flow and clinical outcomes remains undefined. We performed a systematic review and meta-analysis to summarize the association between atten...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Jia R,Nie X,Li H,Zhu H,Pu L,Li X,Han J,Yang D,Meng S,Jin Z

    更新日期:2016-03-01 00:00:00

  • LncRNA260-specific siRNA targeting IL28RA gene inhibit cardiomyocytes hypoxic/reoxygenation injury.

    abstract:BACKGROUND:The interleukin 28 receptor alpha (IL28RA) gene was indicated to be associated with apoptosis. However, it was not clear whether long non-coding RNA 260 (lncRNA 260)-specific siRNA targeting IL28RA gene could inhibit hypoxic reoxygenation (H/R) cardiomyocytes injury or not. To explore the mechanisms underlyi...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章


    authors: Gong G,Yang XX,Li Y,Geng HY,Yang ZJ,Wang LS,Kim HJ,Lu XZ

    更新日期:2017-08-01 00:00:00