Lazarus response to treatment of patients with lung cancer and oncogenic mutations in the intensive care unit.

abstract：Background:The objectives of this study were to evaluate the feasibility and safety of robot-assisted thoracic surgery (RATS) using the da Vinci robotic system for mediastinal mass resection and to describe the surgical approach for masses in different mediastinal regions. Methods:We retrospectively reviewed data from...

journal_title：Journal of thoracic disease

authors： Chen K,Zhang X,Jin R,Xiang J,Han D,Zhang Y,Li H

更新日期：2020-02-01 00:00:00

abstract：:Patients with locally advanced esophageal cancer are treated with definitive chemoradiation (dCXRT) for a number of reasons. Some patients are never referred to a surgeon for a con-versation about surgery, others decline surgery, and some are not candidates for surgery due to a sag in performance status secondary to t...

journal_title：Journal of thoracic disease

authors： Hofstetter WL

更新日期：2014-05-01 00:00:00

abstract：:A 47-year-old man was referred to our hospital because of a 2-month history of dry cough, 2-kg weight loss, and a feeling of abdominal fullness. The PET-CT scan depicts the intense standard uptake values (SUVs) of the anterior and subphrenic lymphnodes, and intraperitoneal cavity, especially in the omentum, while, no ...

journal_title：Journal of thoracic disease

authors： Saraya T,Yokoyama T,Ishii H,Tanaka Y,Tsujimoto N,Ogawa Y,Sohara E,Nakajima A,Inui T,Sayuki H,Fujiwara M,Oka T,Kawachi R,Goya T,Takizawa H,Goto H

更新日期：2013-02-01 00:00:00

abstract：Background:To evaluate the safety of resection of anterior mediastinal lesions involving the left innominate vein (LIV) and analyze the risk factors affecting LIV resection safety. Methods:Patients who underwent anterior mediastinal lesion and LIV resection from January 2010 to December 2018 in the Department of Thora...

journal_title：Journal of thoracic disease

authors： Wang HQ,Tian F,Wei M,Chen LH,Cheng SY,Feng Z,Ma J,Zhang TY,Guo YZ,Yin XL,Zhao ZW,Zhou YA

更新日期：2020-03-01 00:00:00

abstract：Background:It is important to identify patients with esophageal squamous cell carcinoma (ESCC) in T1b stage that are the least likely to metastasize on the lymph nodes, to undergo endoscopic resection, especially for the patients unfit for esophagectomy. The relationship between endoscopic morphology and frequency of n...

journal_title：Journal of thoracic disease

authors： Zhuge L,Wang S,Xie J,Huang B,Zheng D,Zheng S,Mao H,Pennathur A,Sanchez MV,Luketich JD,Xiang J,Chen H,Zhang J

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Red cell distribution width (RDW) might be a novel biomarker that reflects multiple physiological impairments related to atherosclerosis and coronary artery diseases (CAD). We conducted this systematic review and meta-analysis to evaluate the association of RDW between all-cause mortality and fatal/non-fatal...

journal_title：Journal of thoracic disease

authors： Su C,Liao LZ,Song Y,Xu ZW,Mei WY

更新日期：2014-10-01 00:00:00

abstract：:Recent studies have demonstrated that there are differences among races in efficacy, tolerance and other outcomes in oncologic care. Some of these differences may be explained by different pharmacogenetics; however, social and environmental factors that can affect oncology practice are relatively underestimated. In th...

journal_title：Journal of thoracic disease

authors： Komiya T,Chaaya G,Deshotels L,Wang A

更新日期：2020-07-01 00:00:00

abstract：:We report a case involving a female patient with primary hyperparathyroidism arising from a middle mediastinal parathyroid adenoma. Initial diagnosis was made based on a history of polyuria and recurrent renal colic. At the age of 77 she underwent videoscopic assisted mediastinoscopy (VAM) for resection of the adenoma...

journal_title：Journal of thoracic disease

authors： Razzak R,McMullen T,Bédard EL

更新日期：2016-09-01 00:00:00

abstract：:Diagnosing pleural effusion is challenging, especially in patients with malignant or benign fibrothorax, which is difficult to sample using standard flexible forceps (SFF) via flex-rigid pleuroscopy. An adequate sample is crucial for the differential diagnosis of malignant fibrothorax (malignant pleural mesothelioma, ...

journal_title：Journal of thoracic disease

authors： Wang XB,Yin Y,Miao Y,Eberhardt R,Hou G,Herth FJ,Kang J

更新日期：2016-11-01 00:00:00

abstract：Background:Retrospective compared the results of root reconstruction and root replacement for acute type A aortic dissection (ATAAD) patients and observed the rate of aortic insufficiency (AI) and aortic root dilation in the midterm follow-up period. Methods:From 2008-2016, 427 ATAAD patients received surgical therapy...

journal_title：Journal of thoracic disease

authors： Xue Y,Zhou Q,Pan J,Cao H,Fan F,Zhu X,Chong H,Wang D

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:To investigate the effect of percutaneous electrical stimulation on chemotherapy-induced bone marrow suppression in patients with lung cancer. METHODS:From December 2014 to August 2015, one hundred ninety-one non-small cell lung cancer patients with chemotherapy naive were randomly divided into control grou...

journal_title：Journal of thoracic disease

authors： Hou L,Gu F,Gao G,Zhou C

更新日期：2017-03-01 00:00:00

abstract：Background:Consolidation durvalumab improved overall survival (OS) in locally advanced non-small cell lung cancer (LA-NSCLC) treated with chemoradiotherapy (CRT) in the PACIFIC trial; however, pneumonitis was increased with durvalumab. We sought to examine real-world outcomes with the PACIFIC paradigm, especially facto...

journal_title：Journal of thoracic disease

authors： Hassanzadeh C,Sita T,Savoor R,Samson PP,Bradley J,Gentile M,Roach M,Mohindra N,Waqar S,Kruser TJ,Robinson C

更新日期：2020-11-01 00:00:00

abstract：:Minimally invasive esophagectomy (MIE) is increasingly accepted in the treatment of locoregional or advanced esophageal cancer. Laparoscopic-thoracoscopic Ivor-Lewis esophagectomy has been proved to be effective in treating middle and distal esophageal cancer, however, intrathoracic esophagogastric anastomosis is tech...

journal_title：Journal of thoracic disease

authors： Shen G,Pan SB,Wu M,Zhang S,Xu XF,Chen G

更新日期：2013-12-01 00:00:00

abstract：Background:Functional mitral valve regurgitation is a frequent consequence of left ventricular dysfunction in patients with severe heart failure and is associated with a poor prognosis. It is hypothesized that in this patient group the mitral valve repair, respectively replacement, improves hemodynamics and clinical sy...

journal_title：Journal of thoracic disease

authors： Dogan G,Hanke JS,Ricklefs M,Chatterjee A,Feldmann C,Mashaqi B,Deniz E,Haverich A,Schmitto JD

更新日期：2018-06-01 00:00:00

abstract：:Newly-appearing lung nodules on surveillance imaging in patients with pre-existing lung cancer can present a diagnostic dilemma when attempting to differentiate between metastatic disease, infection, and other inflammatory conditions. Here we report a case of an EGFR-/ALK-/BRAF+ metastatic adenocarcinoma patient who u...

journal_title：Journal of thoracic disease

authors： Kalchiem-Dekel O,Paulk A,Kligerman SJ,Burke AP,Shah NG,Dixon RK

更新日期：2017-12-01 00:00:00

abstract：:Bioresorbable vascular scaffolds (BVS) represent a disruptive technology that has caused a new revolution in interventional cardiology. BVS appear to be particularly appealing in patients presenting with an acute myocardial infarction (MI). The available evidence on the value of BVS implantation in this challenging sc...

journal_title：Journal of thoracic disease

authors： Alfonso F,Cuesta J,Bastante T,Rivero F,García-Guimaraes M,Alvarado T,Benedicto A,Cortese B,Byrne R,Kastrati A

更新日期：2016-06-01 00:00:00

abstract：Background:Although emphysema and small cell lung cancer (SCLC) are prevalent in smokers, no previous study has investigated the prognostic impact of computed tomography (CT)-determined emphysema in SCLC. This study was undertaken to analyze the prognostic value of emphysema scores as determined by baseline CT scans in...

journal_title：Journal of thoracic disease

authors： Lee HY,Kim EY,Kim YS,Ahn HK,Kim YK

更新日期：2018-02-01 00:00:00

abstract：Background:The primary objective of the study was to evaluate the health-related quality of life (HRQL) of patients with benign post-intubation tracheal stenosis considered as unfit for surgical treatment. Secondary objectives were: (I) to determine if clinical variables (gender, age, total treatment time, and type of ...

journal_title：Journal of thoracic disease

authors： Bibas BJ,Cardoso PFG,Salati M,Minamoto H,Luiz Tamagno MF,Terra RM,Pêgo-Fernandes PM

更新日期：2018-08-01 00:00:00

abstract：Background:Allergic asthma is a complex genetic disorder that involves interactions between genetic and environmental factors. Usage of PTEN may be a good therapeutic strategy for the management of allergic inflammation. Thus, the present study aims to explore the effects of phosphatase and tensin homolog (PTEN) gene s...

journal_title：Journal of thoracic disease

authors： Wen X,Yan J,Han XR,Zheng GH,Tang R,Liu LF,Wu DM,Lu J,Zheng YL

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Hand sewn cervical esophagogastric anastomosis (CEGA) is regarded as preferred technique by surgeons after esophagectomy. However, considering the anastomotic leakage and stricture, the optimal technique for performing this anastomosis is still under debate. METHODS:Between November 2010 and September 2012,...

journal_title：Journal of thoracic disease

authors： Feng F,Sun L,Xu G,Hong L,Yang J,Cai L,Li G,Guo M,Lian X,Zhang H

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:In patients with prior cardiac surgery requiring re-operative coronary and valve surgery, a hybrid approach of percutaneous coronary intervention followed by minimally invasive valve surgery (PCI + MIVS) may be an alternative to the standard median sternotomy coronary artery bypass and valve surgery (CABG + ...

journal_title：Journal of thoracic disease

authors： Santana O,Xydas S,Williams RF,LaPietra A,Mawad M,Wigley JC,Beohar N,Mihos CG

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:A retrospective analysis of patients undergoing cancer surgery suggested that using local anesthetics could reduce cancer recurrence and improve survival rate. Previous studies have indicated that local anesthetics may induce apoptosis in several kinds of cells in vitro, but the mechanism is unclear. METHOD...

journal_title：Journal of thoracic disease

authors： Wang HW,Wang LY,Jiang L,Tian SM,Zhong TD,Fang XM

更新日期：2016-10-01 00:00:00

abstract：Background:Continuous positive airway pressure (CPAP), the best available treatment for obstructive sleep apnea (OSA), requires long-term compliance to be effective. Behavioral interventions may be used to improve adherence to CPAP. We aimed to investigate whether positive or negative message framing impacts on CPAP co...

journal_title：Journal of thoracic disease

authors： Pengo MF,Czaban M,Berry MP,Nirmalan P,Brown R,Birdseye A,Woroszyl A,Chapman J,Kent BD,Hart N,Rossi GP,Steier J

更新日期：2018-01-01 00:00:00

abstract：Background:The impact of radiation dose to the heart in early-stage lung cancer patients treated with definitive stereotactic body radiation therapy (SBRT) is not well known. We, therefore, analyzed whether higher radiation dose to the heart would lead to an increase in cardiac toxicity and overall mortality. Methods:...

journal_title：Journal of thoracic disease

authors： Reshko LB,Kalman NS,Hugo GD,Weiss E

更新日期：2018-04-01 00:00:00

abstract：Background:Complete resection is the mainstay of treatment for thymoma, but few studies have investigated the extent of resection on normal thymus. Extended thymectomy is considered the treatment of choice for myasthenic patients with thymoma, while the optimal therapy for non-myasthenic patients is still a matter of d...

journal_title：Journal of thoracic disease

authors： Tassi V,Ceccarelli S,Zannori C,Gili A,Daddi N,Bellezza G,Ascani S,Liberati AM,Puma F

更新日期：2017-10-01 00:00:00

abstract：Background:Operative safety and oncologic adequacy of thoracoscopic sleeve lobectomy remain controversial. As such, the purpose of this meta-analysis was to evaluate evidence comparing thoracoscopy and thoracotomy in sleeve lobectomy for centrally located non-small cell lung cancer (NSCLC). Methods:Electronic searches...

journal_title：Journal of thoracic disease

authors： Zhong Y,Wang Y,Hu X,Wang G,She Y,Deng J,Zhang L,Peng Q,Zhu Y,Jiang G,Yang M,Xie D,Chen C

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Although N-ERC/mesothelin (N-ERC) is an attractive diagnostic and treatment monitoring biomarker for malignant pleural mesothelioma (MPM), its clinical utility for predicting the prognosis has not yet been clarified. The aim of this study is to investigate whether the serum N-ERC level can accurately predict...

journal_title：Journal of thoracic disease

authors： Mori T,Tajima K,Hirama M,Sato T,Kido K,Iwakami S,Sasaki S,Iwase A,Shiomi K,Maeda M,Hino O,Takahashi K

更新日期：2013-04-01 00:00:00

abstract：Background:Thymic carcinoma (TC) is a rare mediastinal tumor, and patients with stage IV TC have a poor prognosis. No optimal chemotherapeutic regimen has yet been established. In this study, we evaluated the efficacy and safety of S-1 as a salvage mono-therapy in stage IV TC. Methods:Patients with histologically conf...

journal_title：Journal of thoracic disease

authors： Wang CL,Gao LT,Lu CX

更新日期：2019-07-01 00:00:00

abstract：Background:The purpose of our study was to investigate the correlation between tumor volume (TV) and each subtype of thymic epithelial tumors (TETs) based on the World Health Organization (WHO) classification and Masaoka staging. Methods:Sixty-one consecutive patients (45 thymomas and 16 thymic carcinomas) were studie...

journal_title：Journal of thoracic disease

authors： Sato Y,Yanagawa M,Hata A,Enchi Y,Kikuchi N,Honda O,Nakanishi K,Tomiyama N

更新日期：2018-10-01 00:00:00

abstract：:In this study, we report the case of a 42-year-old female patient who was diagnosed with hemangioma in the pericardium connected to the main pulmonary artery. Chest CT revealed a hypodense, well-marginated, mass-like lesion, probably connected to the main pulmonary artery, and multiple heterogeneous attenuations were ...

journal_title：Journal of thoracic disease

authors： Kim IS,Kim JJ,Choi SY,Jeong SC,Chang E,Kim YH

更新日期：2017-10-01 00:00:00