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Health-related quality of life evaluation in patients with non-surgical benign tracheal stenosis.

Abstract：

Background:The primary objective of the study was to evaluate the health-related quality of life (HRQL) of patients with benign post-intubation tracheal stenosis considered as unfit for surgical treatment. Secondary objectives were: (I) to determine if clinical variables (gender, age, total treatment time, and type of tracheal device) could influence HRQL and (II) to compare the results with a normal standardized population. Methods:Prospective study between August-2014 and December-2016 including patients with tracheal stenosis treated with silicone stents, T-Tubes or tracheostomy. Candidates to airway resection and reconstruction were excluded from the analysis. HRQL was assessed with the SF-36 Health Questionnaire. Backward stepwise regression model analyzed the influence of clinical variables on the SF-36 domains and component summaries. Norm-based results were compared with normative data. Alpha error was 5%. Results:Ninety-three patients (62M/31F; mean age 38±14 years) were included. Mean overall HRQL in all 8 SF-36 domains was poor. Lowest scores were in the role physical (mean 31.7±38), bodily pain (mean 39.2±35), and role emotional domain (mean 48.7±40). The physical component summary (PCS) was more affected than the mental (P<0.001). Norm-based results indicated that most domains and both physical and mental summaries were below the mean for the USA normative population. Total stenting time significantly influenced the physical (P=0.001) and mental component summaries (P=0.001). Conclusions:Quality of life of patients with benign tracheal stenosis is severely impaired, and norm-based results indicate that the HRQL is below normative data. Physical and mental discomfort seems to be attenuated by total treatment time.

journal_name

J Thorac Dis

journal_title

Journal of thoracic disease

authors

Bibas BJ,Cardoso PFG,Salati M,Minamoto H,Luiz Tamagno MF,Terra RM,Pêgo-Fernandes PM

doi

10.21037/jtd.2018.07.80

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

4782-4788

issue

8

eissn

2072-1439

issn

2077-6624

pii

jtd-10-08-4782

journal_volume

10

pub_type

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