Visceral pleural invasion in lung adenocarcinoma ≤3 cm with ground-glass opacity: a clinical, pathological and radiological study.

Abstract:

BACKGROUND:Visceral pleural invasion (VPI) had been demonstrated as an aggressive sign in non-small cell lung cancers (NSCLC). However, its incidence and clinical relevance in early lung cancer showing ground glass nodules (GGNs) has not been clarified. METHODS:All consecutive surgically treated patients with solitary GGNs between 2009 and 2013 were reviewed retrospectively. Inclusion criteria were defined as lesions ≤3 cm with pleura abutting on computed tomography (CT) scan and pathologically confirmed NSCLC. RESULTS:Out of 156 enrolled patients, 38 had pathologically confirmed VPI. The incidence of VPI was 41.5% (27/65) if the tumor diameter was larger than 2.0 cm and 14.3% (13/91) if diameter was smaller than 2.0 cm (P<0.001). Further, the incidence was 17.4% (12/69) in pure GGNs and 32.2% (28/87) in part-solid GGNs (P=0.040). The tumor size and the nodule nodule-pleural relationship were significant predictors of positive VPI. In cases with pleural indentation, attachment, and closeness, the incidence was 38.1%, 25.5%, and 5.3%, respectively (P=0.001). All cases were PL0 and PL1, with no PL2 cases observed. CONCLUSIONS:Although VPI was visible in both pure/mix GGNs, it was more common in larger (>2 cm) GGNs. The radiographic findings of nodule abutment or a pleural tag did not reliably predict or exclude VPI. In patients with GGNs, a low rate of PL2 invasion may be observed.

journal_name

J Thorac Dis

authors

Zhao LL,Xie HK,Zhang LP,Zha JY,Zhou FY,Jiang GN,Chen C

doi

10.21037/jtd.2016.05.90

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

1788-97

issue

7

eissn

2072-1439

issn

2077-6624

pii

jtd-08-07-1788

journal_volume

8

pub_type

杂志文章
  • Identifying patients at higher risk of pneumonia after lung resection.

    abstract:BACKGROUND:Pneumonia is considered as one of the most common and serious complications after lung resection. The purpose of this study was to identify the risk factors associated with postoperative pneumonia (POP) after lung resection and to develop a scoring system to stratify patients with increased risk of POP. MET...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2017.04.42

    authors: Liu GW,Sui XZ,Wang SD,Zhao H,Wang J

    更新日期:2017-05-01 00:00:00

  • Patient safety in thoracic surgery and European Society of Thoracic Surgeons checklist.

    abstract::Improving patient safety seems to be a new interesting clinical subject but, in fact, it is no new. It has to do with one of the oldest ethical principles of our profession: curing and not harming. The important research that has been done in a short period of time has brought in new insight to this complex area that ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.3978/j.issn.2072-1439.2015.03.13

    authors: Novoa NM

    更新日期:2015-04-01 00:00:00

  • A comparison of longitudinal and transverse approaches to ultrasound-guided axillary vein cannulation by experienced operators.

    abstract:BACKGROUND:The axillary vein is an easily accessible vessel that can be used for ultrasound-guided central vascular access and offers an alternative to the internal jugular and subclavian veins. The objective of this study was to identify which transducer orientation, longitudinal or transverse, is better for imaging t...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2017.03.137

    authors: He YZ,Zhong M,Wu W,Song JQ,Zhu DM

    更新日期:2017-04-01 00:00:00

  • Precontrol of the pulmonary artery during thoracoscopic left upper lobectomy and systemic lymph node dissection.

    abstract::The main reasons of emergent conversion during thoracoscopic lobectomy included tumor invasion, hilar lymph node (LN) metastasis, and lymphoid tuberculosis. We presented a video which depicted a three-portal thoracoscopic left upper lobectomy with dissection of large LNs. Severe adhesions between a large LN and the fi...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.03.56

    authors: Ma L,Mei J,Liu C,Liu L

    更新日期:2016-05-01 00:00:00

  • Value of delayed 18F-FDG PET in the diagnosis of solitary pulmonary nodule.

    abstract::Performing dual point 18F-FDG PET scans of solitary pulmonary nodules at an initial SUV (max) <2.5 is a useful technique. However, prolonging second image acquisition from 120 to 180 min does not appear to improve accuracy. Dual time 18F-FDG PET is not useful in differentiating benign and malignant pulmonary nodules w...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.3978/j.issn.2072-1439.2013.06.05

    authors: Khan AN,Al-Jahdali H

    更新日期:2013-06-01 00:00:00

  • The utility of three-dimensional computed tomography for prediction of tumor invasiveness in clinical stage IA lung adenocarcinoma.

    abstract:Background:It is critical to have an accurate measurement of solid tumor size in order to predict the invasiveness of small lung adenocarcinomas. Some lesions cannot be measured accurately via High-resolution computed tomography (HRCT) due to their irregular shape and unclear borders. For this reason, we evaluated the ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd-20-2131

    authors: Kawaguchi Y,Nakao M,Omura K,Iwamoto N,Ozawa H,Kondo Y,Ichinose J,Matsuura Y,Okumura S,Mun M

    更新日期:2020-12-01 00:00:00

  • In the era of ultrasound technology, could conventional trans-bronchial needle aspiration still play a role in lung cancer mediastinal staging?

    abstract:BACKGROUND:To evaluate the feasibility of a combined strategy including conventional-trans-bronchial needle aspiration biopsy (C-TBNA) and endobronchial ultrasounds transbronchial needle aspiration (EBUS-TBNA) for sampling mediastinal adenopathies in patients with lung cancer in order to determinate whether in the era ...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2017.04.13

    authors: Fiorelli A,Santoriello C,Di Natale D,Cascone R,Musella V,Mastromarino R,Serra N,Vicidomini G,Polverino M,Santini M

    更新日期:2017-05-01 00:00:00

  • Video-assisted thoracoscopic surgery segmentectomy by non-intubated or intubated anesthesia: a comparative analysis of short-term outcome.

    abstract:BACKGROUND:The aim of this study was to reveal the short-term outcomes of video-assisted thoracoscopic surgery (VATS) segmentectomy without tracheal intubation compared with intubated general anesthesia with one-lung ventilation (OLV). METHODS:We performed a retrospective review of our institutional database of consec...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.02.50

    authors: Guo Z,Yin W,Pan H,Zhang X,Xu X,Shao W,Chen H,He J

    更新日期:2016-03-01 00:00:00

  • Surgical and endoscopic treatment for COPD: patients selection, techniques and results.

    abstract::Chronic obstructive pulmonary disease (COPD) is a very heterogeneous disease characterised by an obstructive lung pattern that constitutes worldwide a major cause of high morbidity and mortality. In the last decades, lung volume reduction surgery (LVRS) has demonstrated to be a potential good alternative to transplant...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.21037/jtd.2018.06.156

    authors: Minervini F,Kestenholz PB,Paolini V,Pesci A,Libretti L,Bertolaccini L,Scarci M

    更新日期:2018-10-01 00:00:00

  • Long-term outcomes of multiple and single arterial off-pump coronary artery bypass grafting.

    abstract:Background:To compare the clinical outcomes between multiple arterial (MA) and single arterial (SA) off-pump coronary artery bypass grafting (OPCAB) when applied to left main coronary disease or three-vessel disease. Methods:A total of 537 patients with left main coronary disease or three-vessel disease underwent MA O...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2019.01.101

    authors: Zhu P,Chen A,Wang Z,Ye X,Zhou M,Liu J,Zhao Q

    更新日期:2019-03-01 00:00:00

  • Analysing the reasons of failure of surgical mitral repair approaches-do we need to better think in biomechanics?

    abstract::The failure of mitral valve repair procedures revealed in the outcomes of the recent randomized studies is suggesting the necessity for a better understanding of the biomechanical mechanisms underlying the failure of the surgical approaches. Use of biomechanical modelling and finite element analysis (FEA) in cardiovas...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2017.06.33

    authors: Fraldi M,Spadaccio C,Mihos CG,Nappi F

    更新日期:2017-06-01 00:00:00

  • The development of uniportal video-assisted thoracoscopic surgery in São Paulo: from diagnosis to lobectomy.

    abstract:BACKGROUND:The use of uniportal video-assisted thoracoscopic surgery (VATS) has been increasing worldwide. Our main goal was to describe the evolution of uniportal surgery in the biggest private hospital in Latin America that is located in São Paulo, Brazil. METHODS:This descriptive and retrospective study included pa...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.10.79

    authors: de Oliveira A,Couto TAPP

    更新日期:2017-04-01 00:00:00

  • True video-assisted thoracic surgery for early-stage non-small cell lung cancer.

    abstract::Since its inception, minimally invasive surgery has made a dramatic impact on all branches of surgery. Video-assisted thoracic surgery (VATS) lobectomy for early-stage non-small cell lung cancer (NSCLC) was first described in the early 1990s and has since become popular in a number of tertiary referral centers. Propon...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:

    authors: Cao CQ,Stine ML,Yan TD

    更新日期:2009-12-01 00:00:00

  • Pulmonary arteriovenous malformations presenting as refractory heart failure.

    abstract::A 22-year-old young man with a history of idiopathic dilated cardiomyopathy (IDC) was admitted to our hospital due to difficult-to-control heart failure. A thoracic X-ray showed multiple nodules at the both pulmonary hilus and upper lobe of the right lung. Computed tomography (CT) angiography of the thorax confirmed a...

    journal_title:Journal of thoracic disease

    pub_type:

    doi:10.3978/j.issn.2072-1439.2014.07.39

    authors: Liao Y,Chen KH,Huang GY,Song W

    更新日期:2014-09-01 00:00:00

  • Right anterior mini-thoracotomy vs. conventional sternotomy for aortic valve replacement: a propensity-matched comparison.

    abstract:Background:Right anterior mini-thoracotomy (MIAVR) is a promising technique for aortic valve replacement. We aimed at comparing its outcomes with those obtained in a propensity-matched group of patients undergoing sternotomy at our two high-volume centers. Methods:Main clinical and operative data of patients undergoin...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2018.03.47

    authors: Del Giglio M,Mikus E,Nerla R,Micari A,Calvi S,Tripodi A,Campo G,Maietti E,Castriota F,Cremonesi A

    更新日期:2018-03-01 00:00:00

  • Hemangioma originating from the main pulmonary artery.

    abstract::In this study, we report the case of a 42-year-old female patient who was diagnosed with hemangioma in the pericardium connected to the main pulmonary artery. Chest CT revealed a hypodense, well-marginated, mass-like lesion, probably connected to the main pulmonary artery, and multiple heterogeneous attenuations were ...

    journal_title:Journal of thoracic disease

    pub_type:

    doi:10.21037/jtd.2017.08.129

    authors: Kim IS,Kim JJ,Choi SY,Jeong SC,Chang E,Kim YH

    更新日期:2017-10-01 00:00:00

  • Sequencing postoperative radiotherapy and adjuvant chemotherapy in non-small cell lung cancer: unanswered questions on the not evidence-based approach.

    abstract::This editorial comments on the study by Lee et al. which reported on the use of postoperative radiotherapy (PORT) as first strategy after resection of stage IIIA-pN2 non-small cell lung cancer (NSCLC). After completion of PORT, 41% of patients received postoperative chemotherapy (POCT). The five-year overall survival ...

    journal_title:Journal of thoracic disease

    pub_type: 评论,杂志文章

    doi:10.21037/jtd.2016.05.76

    authors: Kepka L,Socha J,Rucinska M,Wasilewska-Tesluk E,Komosinska K

    更新日期:2016-07-01 00:00:00

  • Mechanical interventricular dependency supports hemodynamics in tako-tsubo cardiomyopathy.

    abstract:Background:Although morphological abnormalities of the heart appear to be remarkable, most patients with tako-tsubo cardiomyopathy (TTC) remain clinically stable. We investigate real time changes in the left ventricular (LV) and right ventricular (RV) mechanics and function to explore the mechanism to preserve hemodyna...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2018.04.143

    authors: Lei J,Sun Z,Lyu L,Green RG,Scalzetti E,Feiglin D,Wang J,Liu K

    更新日期:2018-05-01 00:00:00

  • Learning curve for robot-assisted lobectomy of lung cancer.

    abstract:Background:Robotic lobectomy is widely used for lung cancer treatment. So far, few studies have been performed to systematically analyze the learning curve. Our purpose is to define the learning curve to provide a training guideline of this technique. Methods:A total of 208 consecutive patients with primary lung cance...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2019.05.71

    authors: Song G,Sun X,Miao S,Li S,Zhao Y,Xuan Y,Qiu T,Niu Z,Song J,Jiao W

    更新日期:2019-06-01 00:00:00

  • Applications of cell-free circulating tumor DNA detection in EGFR mutant lung cancer.

    abstract::Analyses of cell-free tumor DNA (ctDNA) have provided a non-invasive strategy for cancer diagnosis, the identification of molecular aberrations for treatment identification, and evaluation of tumor response. Sensitive and specific ctDNA sequencing strategies have allowed for implementation into clinical practice for t...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.21037/jtd.2020.01.66

    authors: Bulbul A,Leal A,Husain H

    更新日期:2020-05-01 00:00:00

  • Glucose-insulin-potassium correlates with hemodynamic improvement in patients with septic myocardial dysfunction.

    abstract:BACKGROUND:Glucose-insulin-potassium (GIK) demonstrates a cardioprotective effect by providing metabolic support and anti-inflammatory action, and may be useful in septic myocardial depression. The aim of this study was to examine the relationship between GIK and hemodynamic outcomes in septic shock patients with myoca...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.12.10

    authors: Kim WY,Baek MS,Kim YS,Seo J,Huh JW,Lim CM,Koh Y,Hong SB

    更新日期:2016-12-01 00:00:00

  • Preliminary evaluation and discussion of the safety of left innominate vein resection.

    abstract:Background:To evaluate the safety of resection of anterior mediastinal lesions involving the left innominate vein (LIV) and analyze the risk factors affecting LIV resection safety. Methods:Patients who underwent anterior mediastinal lesion and LIV resection from January 2010 to December 2018 in the Department of Thora...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2020.01.29

    authors: Wang HQ,Tian F,Wei M,Chen LH,Cheng SY,Feng Z,Ma J,Zhang TY,Guo YZ,Yin XL,Zhao ZW,Zhou YA

    更新日期:2020-03-01 00:00:00

  • Use of efficient purse-string stapling technique for esophagogastric anastomosis in minimally invasive Ivor Lewis esophagectomy.

    abstract::Minimally invasive esophagectomy (MIE) is increasingly accepted in the treatment of locoregional or advanced esophageal cancer. Laparoscopic-thoracoscopic Ivor-Lewis esophagectomy has been proved to be effective in treating middle and distal esophageal cancer, however, intrathoracic esophagogastric anastomosis is tech...

    journal_title:Journal of thoracic disease

    pub_type:

    doi:10.3978/j.issn.2072-1439.2013.12.10

    authors: Shen G,Pan SB,Wu M,Zhang S,Xu XF,Chen G

    更新日期:2013-12-01 00:00:00

  • Survival impact of locoregional metachronous malignancy in survival of lung cancer patients who received curative treatment.

    abstract:BACKGROUND:Metachronous malignancy is also found in the lung cancer population and may be identified before or after diagnosis of lung cancer. No prior studies have documented lung cancer patients with metachronous malignancy and its survival impact in this population. The aim of this study was to try to clarify the su...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2016.04.45

    authors: Wen CT,Fu JY,Wu CF,Hsieh MJ,Liu YH,Wu YC,Tsai YH,Wu CY

    更新日期:2016-06-01 00:00:00

  • Analysis of the clinical differentiation of pulmonary sclerosing pneumocytoma and lung cancer.

    abstract:Background:Pulmonary sclerosing pneumocytoma (PSP) is a rare benign lung tumor. This study investigated the diagnostic experience of PSP and lung cancer. Methods:This study is a retrospective study. We observed the locations of lung lesions, imaging form and clinical symptoms, and recorded the surgical complications t...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2017.08.07

    authors: Zhu J

    更新日期:2017-09-01 00:00:00

  • A model based on endoscopic morphology of submucosal esophageal squamous cell carcinoma for determining risk of metastasis on lymph nodes.

    abstract:Background:It is important to identify patients with esophageal squamous cell carcinoma (ESCC) in T1b stage that are the least likely to metastasize on the lymph nodes, to undergo endoscopic resection, especially for the patients unfit for esophagectomy. The relationship between endoscopic morphology and frequency of n...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2018.11.77

    authors: Zhuge L,Wang S,Xie J,Huang B,Zheng D,Zheng S,Mao H,Pennathur A,Sanchez MV,Luketich JD,Xiang J,Chen H,Zhang J

    更新日期:2018-12-01 00:00:00

  • Bridging to lung transplantation with extracorporeal circulatory support: when or when not?

    abstract::Patients with end-stage lung disease who are candidates for lung transplantation may acutely decompensate before a donor organ becomes available. In this scenario, extracorporeal life support (ECLS) may be considered as a bridge to transplant or as a bridge to decision. In the current chapter, we review the indication...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章,评审

    doi:10.21037/jtd.2017.08.117

    authors: Loor G,Simpson L,Parulekar A

    更新日期:2017-09-01 00:00:00

  • The value of a post-polio syndrome self-management programme.

    abstract:Background:Post-polio syndrome is characterised by symptoms of fatigue, pain and new-onset neuromuscular weakness, and emerges decades after the initial poliovirus infection. We sought to evaluate the only post-polio syndrome specific self-management programme in the United Kingdom. Methods:This was a retrospective st...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd-cus-2020-009

    authors: Curtis A,Lee JS,Kaltsakas G,Auyeung V,Shaw S,Hart N,Steier J

    更新日期:2020-10-01 00:00:00

  • Ventilator-associated events: prevalence and mortality in Japan.

    abstract:Background:In 2013, the Centers for Disease Control and Prevention (CDC) issued the concept of the ventilator-associated events (VAEs) as a quality indicator (QI) in the intensive care unit (ICU). A number of studies have been conducted in the United States and other Western countries to evaluate its practicality. Howe...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2018.12.40

    authors: Nakahashi S,Imai H,Imanaka H,Ohshimo S,Satou T,Shima M,Yanagisawa M,Yamashita C,Ogura T,Yamada T,Shime N

    更新日期:2018-12-01 00:00:00

  • Perioperative outcome of lung cancer surgery in women: results from a Spanish nationwide prospective cohort study.

    abstract:Background:To assess possible differences in the perioperative profile between men and women in lung cancer surgery. Methods:A prospective cohort multicenter study was design, in which consecutive patients undergoing curative intent surgery for lung cancer in 24 Thoracic Services throughout Spain were included. Clinic...

    journal_title:Journal of thoracic disease

    pub_type: 杂志文章

    doi:10.21037/jtd.2019.03.30

    authors: Fibla JJ,Molins L,Quero F,Izquierdo JM,Sánchez D,Hernández J,Bayarri C,Boada M,Guirao Á,Cueto A

    更新日期:2019-04-01 00:00:00