A subset of esophageal squamous cell carcinoma patient-derived xenografts respond to cetuximab, which is predicted by high EGFR expression and amplification.

abstract：:Carinal resection (CR) and sleeve pneumonectomy (SP) are one of the challenging issues in thoracic surgery and performed rarely. In spite of the knowledge of the technique, the incidence of postoperative complications is higher compared to standard resections. Adequate patient selection, improved anesthetic management...

journal_title：Journal of thoracic disease

authors： Weder W,Inci I

更新日期：2016-11-01 00:00:00

abstract：Background:The subcategory "solid component of tumor" is a new criterion of tumor categories in the updated eighth edition of the TNM classification. Nevertheless, the predictors of lymph node metastasis among patients with clinical T1 adenocarcinoma, based on the TNM classification 8th edition, remain unclear. This st...

journal_title：Journal of thoracic disease

authors： Nakahashi K,Tsunooka N,Hirayama K,Matsuno M,Endo M,Akahira J,Taguri M

更新日期：2020-05-01 00:00:00

abstract：:This report describes a rare case of benign superior vena cava syndrome (SVCS) accompanying recalcitrant pleural effusion developed secondary to extrinsic compression by anthracotic calcified mediastinal lymphadenopathy which was corrected by surgical bypass graft. An 81-year-old female presented with recalcitrant ple...

journal_title：Journal of thoracic disease

authors： Lee YP,Chun EM,Kim YK,Kim KC

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The analysis of lung artefacts has gained increasing importance as markers of lung pathology. B-line artefact (BLA), caused by a reverberation phenomenon, is the most important lung artefact. In this review, we discuss the current role of BLA in pneumology and explore open questions of the published consensu...

journal_title：Journal of thoracic disease

authors： Dietrich CF,Mathis G,Blaivas M,Volpicelli G,Seibel A,Wastl D,Atkinson NS,Cui XW,Fan M,Yi D

更新日期：2016-06-01 00:00:00

abstract：Background:The incidence of conduction disturbances requiring permanent pacemaker (PPM) implantation following transcatheter aortic valve replacement (TAVR) have remained a common concern. The purpose of this study was to evaluate the impact of postprocedural PPM implantation following TAVR on clinical outcomes. Metho...

journal_title：Journal of thoracic disease

authors： Xi Z,Liu T,Liang J,Zhou YJ,Liu W

更新日期：2019-12-01 00:00:00

abstract：:Non-malignant and malignant obstruction of the tracheal airway causes significant morbidity and mortality. With increased use of artificial airways, benign and iatrogenic complications are increasing. A tracheal stenosis that is less than 5 cm in length can be resected with end-to-end anastomosis. Longer tracheal lesi...

journal_title：Journal of thoracic disease

authors： Delaere P,Van Raemdonck D

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Chronic obstructive pulmonary disease (COPD) represents an increasing healthcare concern as a leading cause of morbidity and mortality worldwide. Our objective was to predict the outcome of COPD patients associated with multiple organ dysfunction syndrome (MODS) by scoring models. METHODS:A re...

journal_title：Journal of thoracic disease

authors： Xiao K,Guo C,Su L,Yan P,Li X,Xie L

更新日期：2015-03-01 00:00:00

abstract：:Sepsis is a medical emergency and life-threatening condition due to a dysregulated host response to infection, which is time-dependent and associated with unacceptably high mortality. Thus, when treating suspicious or confirmed cases of sepsis, clinicians must initiate broad-spectrum antimicrobials within the first ho...

journal_title：Journal of thoracic disease

authors： Martínez ML,Plata-Menchaca EP,Ruiz-Rodríguez JC,Ferrer R

更新日期：2020-03-01 00:00:00

abstract：Background:The pathogenesis of atrial fibrillation (AF) remains unclear. Vascular endothelial growth factors (VEGFs) can stimulate fibrosis within the atrium and ventricle. We hypothesized that there is a relationship between the serum VEGFs/soluble vascular endothelial growth factor receptor (sVEGFRs) levels and AF in...

journal_title：Journal of thoracic disease

authors： Wang K,Liu Y,Huang S,Li H,Hou J,Huang J,Chen J,Feng K,Liang M,Chen G,Wu Z

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Cytomegalovirus (CMV) pneumonia is a major cause of death in immunosuppressed patients. Despite the effective treatment with ganciclovir (GCV) and other antiviral agents, the mortality rate remains between 30% to 50%. Recently, the anti-malarial drug artesunate (ART) wasfound to exhibit significant anti-vira...

journal_title：Journal of thoracic disease

authors： Zeng AH,Ou YY,Guo MM,Dai X,Zhou DZ,Chen R

更新日期：2015-07-01 00:00:00

abstract：Background:Endobronchial stents that are used to treat airway obstruction may migrate over time. These stents can be repositioned. However, not much has been reported about this technique. We retrospectively reviewed our experience with self-expanding metallic stents (SEMS) and attempted to determine-(I) factors relate...

journal_title：Journal of thoracic disease

authors： Biswas A,Jantz MA,Fernandez-Bussy S,Flanagan M,Mehta HJ

更新日期：2020-05-01 00:00:00

abstract：Background:Thoracoscopic surgery (TS) has been used more commonly as a less invasive procedure for early-stage non-small cell lung cancer (NSCLC) than conventional thoracotomy (TH) in Japan. However, limited evidential data are available to compare the treatment efficacy of TS and TH. The purpose of this study was to r...

journal_title：Journal of thoracic disease

authors： Nakao M,Ichinose J,Matsuura Y,Nakagawa K,Okumura S,Mun M

更新日期：2019-07-01 00:00:00

abstract：:Germ cell tumors, like teratoma, typically occur in young adults in their second to fourth decade with equal sex distribution. We firstly report a very rare case of a huge tumor compressed the vital structures of the mediastinum that was diagnosed in a 21-year-old woman at 39 weeks of gestation during a routine prenat...

journal_title：Journal of thoracic disease

authors： Yang M,Shen C,Du H,Wang Y,Che G

更新日期：2014-10-01 00:00:00

abstract：Background:Modern left ventricular assist devices (LVAD) have evolved to become standard of care in severe heart failure (HF) patients. Right HF (RHF) is a major complication responsible for early mortality. Several techniques for temporary right ventricular assist device (t-RVAD) have been described before, baring rel...

journal_title：Journal of thoracic disease

authors： Schmack B,Farag M,Kremer J,Grossekettler L,Brcic A,Raake PW,Kreusser MM,Goldwasser R,Popov AF,Mansur A,Karck M,Ruhparwar A

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Influenza surveillance is carried out in Guangdong province, southern China. A better understanding of influenza seasonality and predominant Subtypes of influenza virus in Guangdong can help to improve evidence-based prevention and control strategies for influenza in the future. MATERIALS AND METHODS:THERE ...

journal_title：Journal of thoracic disease

authors： Lin J,Kang M,Zhong H,Zhang X,Yang F,Ni H,Huang P,Hong T,Ke C,He J

更新日期：2013-08-01 00:00:00

abstract：:Peripheral lung nodule evaluation represents a clinical challenge. Given that many nodules will be incidentally found with lung cancer screening following the publication of the National Lung Screening Trial (NLST), the goal is to find an accurate, safe and minimally-invasive diagnostic modality to biopsy the concerni...

journal_title：Journal of thoracic disease

authors： Arias S,Yarmus L,Argento AC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:We aimed to summarize the diagnostic accuracy of white light bronchoscopy (WLB) and advanced techniques for airway pre-cancerous lesions and early cancer, such as autofluorescence bronchoscopy (AFB), AFB combined with WLB (AFB + WLB) and narrow-band imaging (NBI) bronchoscopy. METHODS:We searched for eligib...

journal_title：Journal of thoracic disease

authors： Zhang J,Wu J,Yang Y,Liao H,Xu Z,Hamblin LT,Jiang L,Depypere L,Ang KL,He J,Liang Z,Huang J,Li J,He Q,Liang W,He J

更新日期：2016-11-01 00:00:00

abstract：Background:We previously reported the techniques for total endoscopic atrial septal defect (ASD) repair on hearts arrested with cardioplegia through three small incisions in the chest wall without aid of a surgical robotic system. The optimal results motivated us to use total thoracoscopic technology for ASD on perfuse...

journal_title：Journal of thoracic disease

authors： Tang Y,Wu Y,Zhu J,Liu X,Zhou J,Huang H,Li M,Dai Y,Han X

更新日期：2018-12-01 00:00:00

abstract：:Acute Stanford type A aortic dissection requires an extremely complex surgical strategy and presents high risk of complications. Although many different procedures were reported to treat this aortic dissection, high mortality rate and incidences of complications still exist. This study presents a 59-year-old lady with...

journal_title：Journal of thoracic disease

authors： Liu L,Qin C,Hou J,Zhu D,Zhang B,Ma H,Guo Y

更新日期：2016-12-01 00:00:00

abstract：:Natural history of acute Stanford type A aortic dissection (AAAD) implies the need of emergent surgical treatment in the vast majority of cases. Nevertheless, conservative treatment has been described to yield acceptable outcomes, when compared to surgery, in selected high risk cases of thrombosed false lumen. We repo...

journal_title：Journal of thoracic disease

authors： Piñón M,Acuña B,Lugo J,Pradas G

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Several studies have demonstrated that reduced lung function is a significant risk factor for lung cancer and increased surgical risk in patients with operable stages of lung cancer. The aim of the study was to perform pulmonary function tests and investigate which is a favorable respiratory function test fo...

journal_title：Journal of thoracic disease

authors： Zarogoulidis P,Kerenidi T,Huang H,Kontakiotis T,Tremma O,Porpodis K,Kalianos A,Rapti A,Foroulis C,Zissimopoulos A,Courcoutsakis N,Zarogoulidis K

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Beta-2 adrenergic receptor (β2AR) downregulation is critical to asthma rescue therapy; however, tolerance, also known as β2AR or bronchodilator desensitization, mechanisms potentially resulting in life-threatening rescue treatment failure remain poorly understood. METHODS:Airway smooth muscle cells (ASMCs) ...

journal_title：Journal of thoracic disease

authors： Ni S,Zhang Y,Wang H,Zhou J,Ding L,Liu H

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Intensity modulated radiotherapy (IMRT) is routinely utilized in the treatment of locally advanced non-small cell lung cancer (NSCLC). RTOG 0617 found that overall survival was impacted by increased low (5 Gy) and intermediate (30 Gy) cardiac doses. We evaluated the impact of esophageal-sparing IMRT on cardi...

journal_title：Journal of thoracic disease

authors： Woodford K,Panettieri V,Ruben JD,Senthi S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Visceral pleural invasion (VPI) had been demonstrated as an aggressive sign in non-small cell lung cancers (NSCLC). However, its incidence and clinical relevance in early lung cancer showing ground glass nodules (GGNs) has not been clarified. METHODS:All consecutive surgically treated patients with solitary...

journal_title：Journal of thoracic disease

authors： Zhao LL,Xie HK,Zhang LP,Zha JY,Zhou FY,Jiang GN,Chen C

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:To assess the feasibility and safety of tubeless video-assisted thoracoscopic surgery (VATS) under non-intubated, intravenous anesthesia with spontaneous ventilation and no placement of a chest tube postoperatively compared with VATS under intubated anesthesia with single-lung mechanical ventilation. METHOD...

journal_title：Journal of thoracic disease

authors： Cui F,Liu J,Li S,Yin W,Xin X,Shao W,He J

更新日期：2016-08-01 00:00:00

abstract：:A novel strategy of one-stage surgery in combination with thoracic endovascular grafting and resection for T4 lung cancer invading the thoracic aorta and spine is described. A 56-year-old man with locally advanced lung cancer infiltrating the aortic wall and spine underwent neoadjuvant chemotherapy and thoracic irradi...

journal_title：Journal of thoracic disease

authors： Sato S,Goto T,Koike T,Okamoto T,Shoji H,Ohashi M,Watanabe K,Tsuchida M

更新日期：2017-11-01 00:00:00

abstract：:Esophageal chondromatous hamartomas are very rare tumors, characterized by proliferating hyaline cartilage cells. We described the case of a 64-year-old woman, with a progressive foreign body sensation in the laryngopharynx caused by an intraluminal pedicled mass. Transcervical esophagectomy was performed and intraope...

journal_title：Journal of thoracic disease

authors： Zhang C,Xu J,Wang Z,He Z,Yang H,Hu J

更新日期：2017-03-01 00:00:00

abstract：:Cases of tracheobronchial foreign body aspiration are frequently encountered emergency cases of childhood; and, delays in its recognition and treatment do result in serious morbidity and mortality. Diagnosis mainly relies on taking history which should indicate what the foreign body is, when it has been aspirated and ...

journal_title：Journal of thoracic disease

authors： Kendigelen P

更新日期：2016-12-01 00:00:00

abstract：Background:Optimal preservation of endothelial integrity of the vessels used as aortocoronary grafts is a crucial determinant of long-term clinical success of coronary artery bypass grafting (CABG). The purpose of this study was to evaluate an impact of two common techniques to harvest left internal thoracic artery (LI...

journal_title：Journal of thoracic disease

authors： Puslecki M,Buczkowski P,Nowicki M,Sujka-Kordowska P,Ligowski M,Misterski M,Stefaniak S,Dąbrowski M,Dabrowska A,Bocianski M,Szarpak L,Ruetzler K,Jemielity M,Perek B

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to determine the safety and feasibility of the use of laryngeal mask airway (LMA) for non-endotracheal intubated anesthesia for patients with pectus excavatum (PE) undergoing thoracoscopic Nuss procedure. METHODS:Between July 2015 and December 2015, 30 selected patients with...

journal_title：Journal of thoracic disease

authors： Du X,Mao S,Cui J,Ma J,Zhang G,Zheng Y,Zhou H,Xie L,Zhang D,Shi R,Chen G

更新日期：2016-08-01 00:00:00