Gelation of plasmonic metal oxide nanocrystals by polymer-induced depletion attractions.

abstract：:Two functional human dUTP pyrophosphatase (dUTPase; EC 3.6.1.23) cDNAs were isolated from a cDNA expression library by genetic complementation in Escherichia coli. These cDNAs differed in size but exhibited a common overlapping DNA sequence. Contained within this sequence was a single long open reading frame sufficien...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： McIntosh EM,Ager DD,Gadsden MH,Haynes RH

更新日期：1992-09-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of unknown cause that afflicts the central nervous system. MS is typified by a highly clonally restricted antigen-driven antibody response that is confined largely to the central nervous system. The major antigenic targets of this response and the...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Williamson RA,Burgoon MP,Owens GP,Ghausi O,Leclerc E,Firme L,Carlson S,Corboy J,Parren PW,Sanna PP,Gilden DH,Burton DR

更新日期：2001-02-13 00:00:00

abstract：:Five peptides corresponding to amino acid sequences predicted from all three reading frames of the nucleotide sequence of the third internal repeat array (IR3) of the Epstein-Barr virus (EBV) genome were synthesized chemically. All five peptides elicited antipeptide antibodies in rabbits. The antiserum raised against ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dillner J,Sternås L,Kallin B,Alexander H,Ehlin-Henriksson B,Jörnvall H,Klein G,Lerner R

更新日期：1984-08-01 00:00:00

abstract：:The rates of reassociation of DNA from a monkey cell line (Vero), from SV40 pseudovirus (consisting of Vero DNA and virus protein coat), and from mature SV40 were measured. The results show that the host DNA in the pseudovirus contains repeated and unique sequences in the same proportions as normal host DNA; hence, no...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Grady L,Axelrod D,Trilling D

更新日期：1970-12-01 00:00:00

abstract：:Understanding the mechanisms by which compounds discovered using cell-based phenotypic screening strategies might exert their effects would be highly augmented by new approaches exploring their potential interactions with the genome. For example, altered androgen receptor (AR) transcriptional programs, including castr...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Jin C,Yang L,Xie M,Lin C,Merkurjev D,Yang JC,Tanasa B,Oh S,Zhang J,Ohgi KA,Zhou H,Li W,Evans CP,Ding S,Rosenfeld MG

更新日期：2014-06-24 00:00:00

abstract：:Atmospheric oxidation of natural and anthropogenic volatile organic compounds (VOCs) leads to secondary organic aerosol (SOA), which constitutes a major and often dominant component of atmospheric fine particulate matter (PM2.5). Recent work demonstrates that rapid autoxidation of organic peroxy radicals (RO2) formed ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Pye HOT,D'Ambro EL,Lee BH,Schobesberger S,Takeuchi M,Zhao Y,Lopez-Hilfiker F,Liu J,Shilling JE,Xing J,Mathur R,Middlebrook AM,Liao J,Welti A,Graus M,Warneke C,de Gouw JA,Holloway JS,Ryerson TB,Pollack IB,Thornton

更新日期：2019-04-02 00:00:00

abstract：:Recent work has demonstrated that Web search volume can "predict the present," meaning that it can be used to accurately track outcomes such as unemployment levels, auto and home sales, and disease prevalence in near real time. Here we show that what consumers are searching for online can also predict their collective...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Goel S,Hofman JM,Lahaie S,Pennock DM,Watts DJ

更新日期：2010-10-12 00:00:00

abstract：:Seed germination is regulated by endogenous hormonal cues and external environmental stimuli such as water, low temperature, and light. After germination, the young seedling must rapidly establish its root system and the photoautotrophic capability appropriate to its surrounding environment. Light and the phytohormone...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chen H,Zhang J,Neff MM,Hong SW,Zhang H,Deng XW,Xiong L

更新日期：2008-03-18 00:00:00

abstract：:A 1,942-base-pair DNA segment encoding the structural gene for diphtheria toxin was sequenced, and the primary structure of the toxin was deduced. Restriction enzyme fragments corresponding to nontoxic or hypotoxic peptides of the toxin were isolated from corynebacteriophage beta and cloned into Escherichia coli on pl...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Greenfield L,Bjorn MJ,Horn G,Fong D,Buck GA,Collier RJ,Kaplan DA

更新日期：1983-11-01 00:00:00

abstract：:Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we used psilocybin, a classic psychedelic found in magic mushrooms, and a task-free functional MRI (fMRI) protocol desi...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Carhart-Harris RL,Erritzoe D,Williams T,Stone JM,Reed LJ,Colasanti A,Tyacke RJ,Leech R,Malizia AL,Murphy K,Hobden P,Evans J,Feilding A,Wise RG,Nutt DJ

更新日期：2012-02-07 00:00:00

abstract：:Glial fibrillary acidic protein (GFAP) is an intermediate-filament (IF) protein that is highly specific for cells of astroglial lineage, although its tissue-specific role is speculative. Determination of the primary structure of this protein should be of importance for understanding the functional role it plays in ast...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Reeves SA,Helman LJ,Allison A,Israel MA

更新日期：1989-07-01 00:00:00

abstract：:IL-7 and thymic stromal lymphopoietin (TSLP) are two major cytokines controlling murine B cell development. IL-7 has been studied extensively, but only recently has it become possible to unravel the role of TSLP in detail. We studied the biological activities of TSLP in B cell development at distinct ages in the mouse...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vosshenrich CA,Cumano A,Müller W,Di Santo JP,Vieira P

更新日期：2004-07-27 00:00:00

abstract：:Five different selectively deuterated analogs of staphylococcal nuclease (Foggi) were prepared having all but a selected few hydrogen atoms in the enzyme molecule replaced by deuterium. The (1)H-NMR spectra of these analogs are extremely simplified, since they consist of lines arising only from the remaining protonate...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Putter I,Barreto A,Markley JL,Jardetzky O

更新日期：1969-12-01 00:00:00

abstract：:The gene for the RNA-dependent eIF-2 alpha protein kinase (PKR) was isolated from mouse genomic DNA and characterized. The mouse PKR gene contains 16 exons and spans about 28 kilobase pairs. Exon 1 is untranslated; the AUG translation initiation site is located early in the second exon. Exon 16 includes the UAG transl...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Tanaka H,Samuel CE

更新日期：1994-08-16 00:00:00

abstract：:Short oxygen-halogen interactions have been known in organic chemistry since the 1950s and recently have been exploited in the design of supramolecular assemblies. The present survey of protein and nucleic acid structures reveals similar halogen bonds as potentially stabilizing inter- and intramolecular interactions t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Auffinger P,Hays FA,Westhof E,Ho PS

更新日期：2004-11-30 00:00:00

abstract：:Monkeypox virus (MPV) is a virulent human pathogen that has gained increased attention because of its potential use as a bioterrorism agent and inadvertent introduction into North America in 2003. The US outbreak also provided an important opportunity to study MPV-specific T cell immunity. Although MPV-specific CD4(+)...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hammarlund E,Dasgupta A,Pinilla C,Norori P,Früh K,Slifka MK

更新日期：2008-09-23 00:00:00

abstract：:The bacterial superantigen staphylococcal enterotoxin A (SEA) is an extremely potent activator of T lymphocytes when presented on major histocompatibility complex (MHC) class II molecules. To develop a tumor-specific superantigen for cancer therapy, we have made a recombinant fusion protein of SEA and the Fab region o...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dohlsten M,Abrahmsén L,Björk P,Lando PA,Hedlund G,Forsberg G,Brodin T,Gascoigne NR,Förberg C,Lind P

更新日期：1994-09-13 00:00:00

abstract：:Selected aspects of the evolutionary process and more specifically of the genetic variation are considered, with an emphasis in studies performed by my group. One key aspect of evolution seems to be the concomitant occurrence of dichotomic, contradictory (dialect) processes. Genetic variation is structured, and the dy...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Salzano FM

更新日期：2000-05-09 00:00:00

abstract：:Previous work indicated that the light chains of a monotypic immunoglobulins G2-K and M-K from a single patient (Ti1) are identical. Our present data show that the monotypic immunoglobulins G and M share idiotypic determinants not present in their isolated light chains or in any of a large number of other immunoglobul...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wang AC,Wilson KS,Hopper JE,Fudenberg HH,Nisonoff A

更新日期：1970-06-01 00:00:00

abstract：:Bone mineralization is an essential step during the embryonic development of vertebrates, and bone serves vital functions in human physiology. To systematically identify unique gene functions essential for osteogenesis, we performed a forward genetic screen in zebrafish and isolated a mutant, no bone (nob), that does ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Huitema LF,Apschner A,Logister I,Spoorendonk KM,Bussmann J,Hammond CL,Schulte-Merker S

更新日期：2012-12-26 00:00:00

abstract：:A unique multicomponent vaccine against serogroup B meningococci incorporates the novel genome-derived proteins fHbp, NHBA, and NadA that may vary in sequence and level of expression. Measuring the effectiveness of such vaccines, using the accepted correlate of protection against invasive meningococcal disease, could ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Donnelly J,Medini D,Boccadifuoco G,Biolchi A,Ward J,Frasch C,Moxon ER,Stella M,Comanducci M,Bambini S,Muzzi A,Andrews W,Chen J,Santos G,Santini L,Boucher P,Serruto D,Pizza M,Rappuoli R,Giuliani MM

更新日期：2010-11-09 00:00:00

abstract：:Certain cheU mutants of Salmonella show inverted chemotactic behavior, being repelled by attractants and attracted by repellents. Such a dramatic change in behavioral pattern would seem at first glance to require drastic and complex alterations in the sensory processing system. In fact, the behavior can be explained b...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Khan S,Macnab RM,DeFranco AL,Koshland DE Jr

更新日期：1978-09-01 00:00:00

abstract：:Anti-immunoglobulin treatment of fura-2-loaded Daudi cells induces a calcium mobilization as judged by the increase in the fluorescence of the dye fura-2, AM. No calcium mobilization by N-fMet-Leu-Phe is observed in these cells. However, exposure of the cells to N-fMet-Leu-Phe after the first hit with anti-immunoglobu...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kalunta CI,Kaptein JS,Niedzin H,Scott SJ,Lee GH,Lad PM

更新日期：1988-12-01 00:00:00

abstract：:Experiments reported here show that some UV-irradiated wild-type T7 phage markers can be rescued efficiently by coinfection with T7 amber mutant phage in a permissive host. Other results show that the segments of a UV-irradiated genome that replicate efficiently are those that also are rescued efficiently during a mar...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Burck KB,Miller RC Jr

更新日期：1978-12-01 00:00:00

abstract：:The isolated beta subunit of hemoglobin Kansas has an oxygen affinity that is as low relative to the oxygen affinity of the beta(A) subunit as the affinity of hemoglobin Kansas is low relative to hemoglobin A. Thus the low affinity properties of hemoglobin Kansas are almost completely reflected in the properties of th...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Riggs A,Gibson QH

更新日期：1973-06-01 00:00:00

abstract：:The prefrontal cortex plays a fundamental role in the working memory functions of the cerebral cortex and is also the site of dysfunction in several neurological and psychiatric disorders, including schizophrenia. Prefrontal neurons are distinguished by their capacity for sustained activity during the time a stimulus ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gao WJ,Krimer LS,Goldman-Rakic PS

更新日期：2001-01-02 00:00:00

abstract：:UDPglucuronosyltransferase [UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific), EC 2.4.1.17] is a group of enzymes with distinct but partially overlapping substrate specificity. A rabbit antiserum raised against one purified rat liver UDPglycuronosyltransferase isoform was specific for UDPglucuronosyl...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chowdhury JR,Novikoff PM,Chowdhury NR,Novikoff AB

更新日期：1985-05-01 00:00:00

abstract：:Sialic acid-recognizing Ig-like lectins (Siglecs) are signaling receptors that modulate immune responses, and are targeted for interactions by certain pathogens. We describe two primate Siglecs that were rendered nonfunctional by single genetic events during hominin evolution after our common ancestor with the chimpan...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wang X,Mitra N,Secundino I,Banda K,Cruz P,Padler-Karavani V,Verhagen A,Reid C,Lari M,Rizzi E,Balsamo C,Corti G,De Bellis G,Longo L,NISC Comparative Sequencing Program.,Beggs W,Caramelli D,Tishkoff SA,Hayakawa T,Gree

更新日期：2012-06-19 00:00:00

abstract：:DEAD-box RNA helicase proteins use the energy of ATP hydrolysis to drive the unwinding of duplex RNA. However, the mechanism that couples ATP utilization to duplex RNA unwinding is unknown. We measured ATP utilization and duplex RNA unwinding by DbpA, a non-processive bacterial DEAD-box RNA helicase specifically activ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Henn A,Cao W,Licciardello N,Heitkamp SE,Hackney DD,De La Cruz EM

更新日期：2010-03-02 00:00:00

abstract：:Seemingly similar individuals often experience drastically different success trajectories, with some repeatedly failing and others consistently succeeding. One explanation is preexisting variability along unobserved fitness dimensions that is revealed gradually through differential achievement. Alternatively, positive...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： van de Rijt A,Kang SM,Restivo M,Patil A

更新日期：2014-05-13 00:00:00