Author Correction: Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11.

abstract：:Lnc2Catlas ( http://lnc2catlas.bioinfotech.org/ ) is an atlas of long noncoding RNAs (lncRNAs) associated with cancer risk. LncRNAs are a class of functional noncoding RNAs with lengths over 200 nt and play a vital role in diverse biological processes. Increasing evidence shows that lncRNA dysfunction is associated wi...

journal_title：Scientific reports

authors： Ren C,An G,Zhao C,Ouyang Z,Bo X,Shu W

更新日期：2018-01-30 00:00:00

abstract：:The North Atlantic is characterized by diatom-dominated spring blooms that results in significant transfer of carbon to higher trophic levels and the deep ocean. These blooms are terminated by limiting silicate concentrations in summer. Numerous regional studies have demonstrated phytoplankton community shifts to ligh...

journal_title：Scientific reports

authors： Hátún H,Azetsu-Scott K,Somavilla R,Rey F,Johnson C,Mathis M,Mikolajewicz U,Coupel P,Tremblay JÉ,Hartman S,Pacariz SV,Salter I,Ólafsson J

更新日期：2017-11-06 00:00:00

abstract：:This paper reports the presence of tear strips on the surface of a Ti-22Al-25Nb alloy sheet stretched at 960 °C. The test piece reveals a "bamboo"-shaped pattern on its surface, which severely affects the quality of the alloy. Microstructure analysis indicates that the formation mechanism of the tear strip is related ...

journal_title：Scientific reports

authors： Zong Y,Shao B,Xu W,Guo B,Shan D

更新日期：2017-05-10 00:00:00

abstract：:This study aimed to investigate the dosimetric characteristics of an isocentrically shielded RapidArc (IS-RA) technique for treatment of locally recurrent nasopharyngeal cancer (lrNPC). In IS-RA, the isocenter was placed at the center of the pre-irradiated brainstem (BS)/spinal cord (SC) and the jaws were set to shiel...

journal_title：Scientific reports

authors： Lu JY,Huang BT,Xing L,Chang DT,Peng X,Xie LX,Lin ZX,Li M

更新日期：2016-05-13 00:00:00

abstract：:The use of misidentified cell lines contaminated by other cell lines and/or microorganisms has generated much confusion in the scientific literature. Detailed characterization of such contaminations is therefore crucial to avoid misinterpretation and ensure robustness and reproducibility of research. Here we use DNA-s...

journal_title：Scientific reports

authors： Loiseau V,Cordaux R,Giraud I,Beby-Defaux A,Lévêque N,Gilbert C

更新日期：2020-09-29 00:00:00

abstract：:Horizontal gene transfer (HGT) was attributed as a major driving force for the innovation and evolution of prokaryotic genomes. Previously, multiple research endeavors were undertaken to decipher HGT in different bacterial lineages. The genus Mycobacterium houses some of the most deadly human pathogens; however, the i...

journal_title：Scientific reports

authors： Panda A,Drancourt M,Tuller T,Pontarotti P

更新日期：2018-10-04 00:00:00

abstract：:Exo70, a key component of the Exocyst complex, plays important roles in human cancer progression beyond exocytosis. However, the expression of Exo70 and its prognostic value for patients with colon cancer has not been well investigated to date. In this study, we observed that the mRNA and protein levels of Exo70 were ...

journal_title：Scientific reports

authors： Xiao L,Zheng K,Lv X,Hou J,Xu L,Zhao Y,Song F,Fan Y,Cao H,Zhang W,Hong X,Zhan YY,Hu T

更新日期：2017-07-11 00:00:00

abstract：:Understanding ethanol-induced stresses and responses in biofuel-producing bacteria at systems level has significant implications in engineering more efficient biofuel producers. We present a computational study of transcriptomic and genomic data of both ethanol-stressed and ethanol-adapted E. coli cells with computati...

journal_title：Scientific reports

authors： Cao H,Wei D,Yang Y,Shang Y,Li G,Zhou Y,Ma Q,Xu Y

更新日期：2017-03-16 00:00:00

abstract：:In many cancers, incidence, treatment efficacy and overall prognosis vary between geographic populations. Studies disentangling the contributing factors may help in both understanding cancer biology and tailoring therapeutic interventions. Ancestry estimation in such studies should preferably be driven by genomic data...

journal_title：Scientific reports

authors： Huang Q,Baudis M

更新日期：2020-03-16 00:00:00

abstract：:Healthy neonates exhibit a well-functioning haemostatic system despite peculiarities regarding composition of clotting factors and inhibitors as well as impaired platelet aggregation. Thrombocytopenia and severe bleeding events are feared in sick infants. Recombinant factor VIIa (rFVIIa) is a haemostatic agent used as...

journal_title：Scientific reports

authors： Haidl H,Pohl S,Leschnik B,Gallistl S,Muntean W,Schlagenhauf A

更新日期：2019-05-29 00:00:00

abstract：:It is well established that CD8(+) T cells play an important role in protective immunity against protozoan infections. However, their role in the course of Neospora caninum infection has not been fully elucidated. Here we report that CD8-deficient mice infected with N. caninum presented higher parasitic loads in the b...

journal_title：Scientific reports

authors： Correia A,Ferreirinha P,Botelho S,Belinha A,Leitão C,Caramalho Í,Teixeira L,González-Fernandéz Á,Appelberg R,Vilanova M

更新日期：2015-10-09 00:00:00

abstract：:The systematics of Oriental freshwater mussels (Bivalvia: Unionidae) is poorly known. Here, we present an integrative revision of the genus Trapezoideus Simpson, 1900 to further understanding of freshwater mussel diversity in the region. We demonstrate that Trapezoideus as currently circumscribed is non-monophyletic, ...

journal_title：Scientific reports

authors： Konopleva ES,Pfeiffer JM,Vikhrev IV,Kondakov AV,Gofarov MY,Aksenova OV,Lunn Z,Chan N,Bolotov IN

更新日期：2019-03-11 00:00:00

abstract：:Clustered regulatory interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) technology is a powerful tool to manipulate the genome with extraordinary simplicity and speed. To generate genetically modified animals, CRISPR/Cas9-mediated genome editing is typically accomplished by microinjectio...

journal_title：Scientific reports

authors： Ma X,Chen C,Veevers J,Zhou X,Ross RS,Feng W,Chen J

更新日期：2017-02-08 00:00:00

abstract：:Both targeted therapy and immunotherapy have been used successfully to treat melanoma, but the development of resistance and poor response rates to the individual therapies has limited their success. Designing rational combinations of targeted therapy and immunotherapy may overcome these obstacles, but requires assess...

journal_title：Scientific reports

authors： Lelliott EJ,Cullinane C,Martin CA,Walker R,Ramsbottom KM,Souza-Fonseca-Guimaraes F,Abuhammad S,Michie J,Kirby L,Young RJ,Slater A,Lau P,Meeth K,Oliaro J,Haynes N,McArthur GA,Sheppard KE

更新日期：2019-02-04 00:00:00

abstract：:Although extensive studies have focused on the development of acute mountain sickness (AMS), the exact mechanisms of AMS are still obscure. In this study, we used isobaric tags for relative and absolute quantitation (iTRAQ) proteomic analysis to identify novel AMS-associated biomarkers in human plasma. After 9 hours o...

journal_title：Scientific reports

authors： Lu H,Wang R,Li W,Xie H,Wang C,Hao Y,Sun Y,Jia Z

更新日期：2018-01-19 00:00:00

abstract：:Flow of non-Newtonian fluids through topologically complex structures is ubiquitous in most biological, industrial and environmental settings. The interplay between local hydrodynamics and the fluid's constitutive law determines the distribution of flow paths. Consequently the spatial heterogeneity of the viscous resi...

journal_title：Scientific reports

authors： Eberhard U,Seybold HJ,Secchi E,Jiménez-Martínez J,Rühs PA,Ofner A,Andrade JS Jr,Holzner M

更新日期：2020-07-16 00:00:00

abstract：:We demonstrate fluorescent Fe embedded magnetic nanodiamonds by ion implantation and two-step annealing. The diamond characteristics with a highly ordered core and a graphite surface layer are maintained after the implantation process. After the two-step annealing process, a bright red fluorescence associated with nit...

journal_title：Scientific reports

authors： Lin BR,Kunuku S,Chen CH,Chen TY,Hsiao TY,Yu HK,Chang YJ,Liao LC,Niu H,Lee CP

更新日期：2019-02-04 00:00:00

abstract：:The bioactive lipid sphingosine 1-phosphate (S1P) is a degradation product of sphingolipids that are particularly abundant in neurons. We have shown previously that neuronal S1P accumulation is toxic leading to ER-stress and an increase in intracellular calcium. To clarify the neuronal function of S1P, we generated br...

journal_title：Scientific reports

authors： Mitroi DN,Deutschmann AU,Raucamp M,Karunakaran I,Glebov K,Hans M,Walter J,Saba J,Gräler M,Ehninger D,Sopova E,Shupliakov O,Swandulla D,van Echten-Deckert G

更新日期：2016-11-24 00:00:00

abstract：:Myostatin (MSTN) is a dominant inhibitor of skeletal muscle development and growth. Mutations in MSTN gene can lead to muscle hypertrophy or double-muscled (DM) phenotype in cattle, sheep, dog and human. However, there has not been reported significant muscle phenotypes in pigs in association with MSTN mutations. Pigs...

journal_title：Scientific reports

authors： Qian L,Tang M,Yang J,Wang Q,Cai C,Jiang S,Li H,Jiang K,Gao P,Ma D,Chen Y,An X,Li K,Cui W

更新日期：2015-09-24 00:00:00

abstract：:The endo-levanase BT1760 of a human gut commensal Bacteroides thetaiotaomicron randomly cuts a β-2,6-linked fructan, levan, into fructo-oligosaccharides providing a prebiotic substrate for gut microbiota. Here we introduce the crystal structure of BT1760 at resolution of 1.65 Å. The fold of the enzyme is typical for G...

journal_title：Scientific reports

authors： Ernits K,Eek P,Lukk T,Visnapuu T,Alamäe T

更新日期：2019-06-11 00:00:00

abstract：:Non-human animals sometimes show marked intraspecific variation in their cognitive abilities that may reflect variation in external inputs and experience during the developmental period. We examined variation in exploration and cognitive performance on a problem-solving task in a large sample of captive orang-utans (P...

journal_title：Scientific reports

authors： Damerius LA,Forss SI,Kosonen ZK,Willems EP,Burkart JM,Call J,Galdikas BM,Liebal K,Haun DB,van Schaik CP

更新日期：2017-01-09 00:00:00

abstract：:Many mathematical models have been published with the purpose of explaining aspects of T-cell development in the thymus. In this manuscript we adapted a four-compartment model of the thymus and used a range of mathematical approaches with the aim of explaining the dynamics of the four main thymocyte populations in the...

journal_title：Scientific reports

authors： Zaharie D,Moleriu RD,Mic FA

更新日期：2016-11-08 00:00:00

abstract：:Adaptive optics (AO) visual simulators based on deformable mirrors, spatial light modulators or optotunable lenses are increasingly used to simulate vision through different multifocal lens designs. However, the correspondence of this simulation with that obtained through real intraocular lenses (IOLs) tested on the s...

journal_title：Scientific reports

authors： Vinas M,Benedi-Garcia C,Aissati S,Pascual D,Akondi V,Dorronsoro C,Marcos S

更新日期：2019-02-07 00:00:00

abstract：:Within year individual variation in the timing of seasonal reproduction within wild bird populations in highly seasonal environments can be pronounced, but the molecular and physiological mechanisms responsible for this variation are unclear. We investigated the relationship between Clock gene poly-Q length, activatio...

journal_title：Scientific reports

authors： Zhang S,Xu X,Wang W,Yang W,Liang W

更新日期：2017-11-03 00:00:00

abstract：:The coiled-coil domain containing 50 (CCDC50) protein is a phosphotyrosine-dependent signalling protein stimulated by epidermal growth factor. It is highly expressed in neuronal cells in the central nervous system; however, the roles of CCDC50 in neuronal development are largely unknown. In this study, we showed that ...

journal_title：Scientific reports

authors： Min JS,Halder D,Yoon JY,Jeon SJ,Jun SY,Lee JR,Lee JJ,Choi MH,Jung CR,Lee D,Kim BJ,Kim NS

更新日期：2020-12-04 00:00:00

abstract：:The mammalian cochlea has historically resisted attempts at high-resolution, non-invasive imaging due to its small size, complex three-dimensional structure, and embedded location within the temporal bone. As a result, little is known about the relationship between an individual's cochlear pathology and hearing functi...

journal_title：Scientific reports

authors： Iyer JS,Batts SA,Chu KK,Sahin MI,Leung HM,Tearney GJ,Stankovic KM

更新日期：2016-09-16 00:00:00

abstract：:This study analyses spatially resolved estimates of mass budget and surface velocity of glaciers in the Zanskar Basin of Western Himalaya in the context of varying debris cover, glacier hypsometry and orientation. The regional glacier mass budget for the period of 1999-2014 is -0.38 ± 0.09 m w.e./a. Individual mass bu...

journal_title：Scientific reports

authors： Bhushan S,Syed TH,Arendt AA,Kulkarni AV,Sinha D

更新日期：2018-06-11 00:00:00

abstract：:Quality assessment of protein models using no other information than the structure of the model itself has been shown to be useful for structure prediction. Here, we introduce two novel methods, ProQRosFA and ProQRosCen, inspired by the state-of-art method ProQ2, but using a completely different description of a prote...

journal_title：Scientific reports

authors： Uziela K,Shu N,Wallner B,Elofsson A

更新日期：2016-10-04 00:00:00

abstract：:Membrane protein oligomerization mediates a wide range of biological events including signal transduction, viral infection and membrane curvature induction. However, the relative contributions of protein-protein and protein-membrane interactions to protein oligomerization remain poorly understood. Here, we used the Ca...

journal_title：Scientific reports

authors： Tao M,Isas JM,Langen R

更新日期：2020-03-24 00:00:00

abstract：:Inbred strains of mice are powerful models for understanding human pregnancy complications. For example, the exclusive mating of CBA/J females to DBA/2J males increases fetal resorption to 20-35% with an associated decline in placentation and maintenance of maternal Th1 immunity. More recently other complications of p...

journal_title：Scientific reports

authors： McKelvey KJ,Yenson VM,Ashton AW,Morris JM,McCracken SA

更新日期：2016-10-21 00:00:00