Abstract:
:The presence of homoeo box sequences in the genomes of vertebrates has suggested that these metazoans possess the equivalent of the homoeotic genes that have a key role in regulating the development of the fruitfly Drosophila melanogaster. We report here that a novel murine homoeo box-containing gene is expressed in embryonal carcinoma stem cells. Transcripts of the sequences that flank the homoeo box of this gene are found in these cells before and after induced differentiation, whereas a specific transcript that seems to contain the homoeo sequence is only present after differentiation.
journal_name
Naturejournal_title
Natureauthors
Colberg-Poley AM,Voss SD,Chowdhury K,Gruss Pdoi
10.1038/314713a0subject
Has Abstractpub_date
1985-04-25 00:00:00pages
713-8issue
6013eissn
0028-0836issn
1476-4687journal_volume
314pub_type
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