Abstract:
:A continuous array of overlapping clones covering the entire human chromosome 21q was constructed from human yeast artificial chromosome libraries using sequence-tagged sites as landmarks specifically detected by polymerase chain reaction. The yeast artificial chromosome contiguous unit starts with pericentromeric and ends with subtelomeric loci of 21q. The resulting order of sequence-tagged sites is consistent with other physical and genetic mapping data. This set of overlapping clones will promote our knowledge of the structure of this chromosome and the function of its genes.
journal_name
Naturejournal_title
Natureauthors
Chumakov I,Rigault P,Guillou S,Ougen P,Billaut A,Guasconi G,Gervy P,LeGall I,Soularue P,Grinas Ldoi
10.1038/359380a0keywords:
subject
Has Abstract,Author List Incompletepub_date
1992-10-01 00:00:00pages
380-7issue
6394eissn
0028-0836issn
1476-4687journal_volume
359pub_type
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