Clonal variation in childhood acute lymphoblastic leukaemia at early and late relapse detected by analyses of phenotype and genotype.

abstract：:The long-term consequences of transient neonatal hypoglycemia are sparsely studied. We performed a follow-up of a cohort of neonates with blood glucose recordings < 1.7 mmol/L (< 30 mg/dL), treated with > 2.5 mmol/L (> 45 mg/dL), compared with healthy siblings. Exclusion criteria were gestational age < 35 weeks, sever...

journal_title：European journal of pediatrics

authors： Rasmussen AH,Wehberg S,Pørtner F,Larsen AM,Filipsen K,Christesen HT

更新日期：2020-12-01 00:00:00

abstract：:Early diagnosis and treatment of phenylketonuria (PKU) in Poland was started in 1965, initially on a voluntary and then on a obligatory basis. Guthrie tests have been used for newborn screening. For confirmation of diagnosis changing with time methods of blood phenylalanine (Phe) and tyrosine estimation were used. In ...

journal_title：European journal of pediatrics

authors： Cabalska MB,Nowaczewska I,Sendecka E,Zorska K

更新日期：1996-07-01 00:00:00

abstract：:In a five-year-old girl with congenital hepatic fibrosis raised erythrocyte sedimentation rate and serum gammaglobulins were noted for 3 years. Needle liver biopsy showed histological features of cholangitis and Klebsiella oxytoca was cultured from a liver biopsy specimen. Antibiotic treatment resulted in normalizatio...

journal_title：European journal of pediatrics

authors： Alvarez F,Hadchouel M,Bernard O

更新日期：1982-11-01 00:00:00

abstract：UNLABELLED:To monitor infant care practices associated with risks for sudden infant death, 400 Belgian families with infants less than 6 months old were questioned by 21 paediatricians during routine visits to local paediatric practices and well baby services (11 in urban centres, 10 in rural areas). Because of incompl...

journal_title：European journal of pediatrics

authors： Kahn A,Bauche P,Groswasser J,Dramaix M,Scaillet S,Working Group, Groupe Belge de Pediatres Francophones.

更新日期：2001-08-01 00:00:00

abstract：:In order to determine the hepatotoxicity of rifampicin in children treated for tuberculosis, a survey was performed of 18 children receiving this medicine in combination with isoniazid. Fifteen of the 18 children (83%) showed a rise in ASAT values and 11 (61%) in ALAT values exceeding 29U/L. Seven children with maxima...

journal_title：European journal of pediatrics

authors： Linna O,Uhari M

更新日期：1980-09-01 00:00:00

abstract：:The triad of adrenocortical insufficiency with alacrima and achalasia is an unusual disease entity in paediatrics. The association of autonomic and peripheral neuropathies has more commonly been reported in older individuals. We describe four children (two siblings) with this disorder, aged between 3 and 6 years at di...

journal_title：European journal of pediatrics

authors： Gazarian M,Cowell CT,Bonney M,Grigor WG

更新日期：1995-01-01 00:00:00

abstract：:Familial hemophagocytic lymphohistiocytosis (FHL) is probably a genetically transmitted disease affecting infants and very young children. Cardinal symptoms are fever, hepatosplenomegaly, and pancytopenia. Frequently meningeal involvement is seen, manifested by neurologic symptoms and a lymphohistiocytic pleocytosis w...

journal_title：European journal of pediatrics

authors： Janka GE

更新日期：1983-06-01 00:00:00

abstract：UNLABELLED:In patients with propionic acidaemia (PA), the increased intracellular concentration of propionyl-CoA leads to a relative abundance of odd-numbered long-chain fatty acids (OLCFAs) in body lipids. We investigated the relative amount of OLCFA in erythrocyte membrane lipids over a period of 1-8 years in five pa...

journal_title：European journal of pediatrics

authors： Sperl W,Murr C,Skladal D,Sass JO,Suormala T,Baumgartner R,Wendel U

更新日期：2000-01-01 00:00:00

abstract：:Vascularization of the arms has been studied by impedance plethysmography (rheography) in eight children with Poland syndrome, a common malformation characterized by unilateral hand anomaly and ipsilateral aplasia of the inferior head of the pectoralis major muscle. A marked decrease of the velocity of the systolic in...

journal_title：European journal of pediatrics

authors： Bouvet JP,Leveque D,Bernetieres F,Gros JJ

更新日期：1978-05-22 00:00:00

abstract：:Human metapneumovirus (hMPV) is a recently discovered pathogen in respiratory tract infection. The published literature suggests milder illness severity in hMPV compared with respiratory syncytial virus (RSV) infection. In two consecutive seasons, 637 nasopharyngeal aspirates from pediatric patients were tested by hMP...

journal_title：European journal of pediatrics

authors： Wilkesmann A,Schildgen O,Eis-Hübinger AM,Geikowski T,Glatzel T,Lentze MJ,Bode U,Simon A

更新日期：2006-07-01 00:00:00

abstract：:A 22 years old female with the late-onset of argininosuccinic aciduria was successfully treated for 5 months with a mixture of essential amino acids and their keto-analogues. There was a marked change in plasma ammonia, plasma amino acids and argininosuccinic acid excretion. A long term anabolic response was reflected...

journal_title：European journal of pediatrics

authors： Böhles H,Heid H,Harms D,Schmid D,Fekl W

更新日期：1978-07-19 00:00:00

abstract：UNLABELLED:Recent evidence has demonstrated the prenatal initiation of childhood obesity as epidemiological studies and animal studies have illustrated the effect of the intrauterine milieu for subsequent development of childhood obesity. This study investigates the relationship between severe childhood obesity and the...

journal_title：European journal of pediatrics

authors： Lausten-Thomsen U,Bille DS,Nässlund I,Folskov L,Larsen T,Holm JC

更新日期：2013-06-01 00:00:00

abstract：:The objectives of this study were to determine if any specific clinical signs, symptoms, or comorbidities could reliably predict underlying feeding difficulty and need for further evaluation (i.e., video swallow study, VSS) in infants with Down syndrome, to establish the prevalence of gastrostomy tube placement (G-tub...

journal_title：European journal of pediatrics

authors： Poskanzer SA,Hobensack VL,Ciciora SL,Santoro SL

更新日期：2020-06-01 00:00:00

abstract：:Infantile hepatic hemangioma is the most common benign liver tumor during infancy. Prompt diagnosis and timely institution of therapy are of utmost importance. Magnetic resonance imaging (MRI) plays a key role in the correct diagnosis and monitoring of treatment. We report on a 15-week-old girl with multifocal infanti...

journal_title：European journal of pediatrics

authors： Bosemani T,Puttgen KB,Huisman TA,Tekes A

更新日期：2012-07-01 00:00:00

abstract：UNLABELLED:This retrospective study attempts to assess the size and growth pattern of the pulmonary artery about 1 year after neonatal arterial switch operation for simple transposition of the great arteries. Sixty-seven patients underwent cardiac catheterization, including catheterization of the right and left pulmona...

journal_title：European journal of pediatrics

authors： Massin MM,Nitsch GB,Däbritz S,Seghaye MC,Messmer BJ,von Bernuth G

更新日期：1998-02-01 00:00:00

abstract：:The clinical spectrum of the perinatal COVID-19 and prospective data on neonatal outcomes remains largely unexplored. Most of the existing literature is in the form of case series or single-centre experience. In this review, we aim to summarize available literature on the clinical spectrum of COVID-19 in neonates and ...

journal_title：European journal of pediatrics

authors： Vardhelli V,Pandita A,Pillai A,Badatya SK

更新日期：2020-11-12 00:00:00

abstract：:Severe hand, foot, and mouth disease (HFMD) is likely to develop critical complications such as brainstem encephalitis, acute pulmonary edema, and circulatory failure, which cause child mortality during outbreaks. This study aims to investigate factors that predict the severity of HFMD. One hundred sixteen in-patient ...

journal_title：European journal of pediatrics

authors： Li Y,Dang S,Deng H,Wang W,Jia X,Gao N,Li M,Wang J

更新日期：2013-05-01 00:00:00

abstract：:This paper describes the design of a study to follow the development of boys and girls in secondary schools from the age of 12 through 17 on an annual basis, in order to acquire more information concerning the growth and development of teenagers. In this study, both physical and psychological characteristics are measu...

journal_title：European journal of pediatrics

authors： Kemper HC,van 't Hof MA

更新日期：1978-10-12 00:00:00

abstract：:The present study was done to evaluate the effect of short-term dietary therapy on 148 dyslipidaemic children (24 familial hypercholesterolaemia, 105 non-familial hypercholesterolaemia and 19 hypertriglyceridaemia), detected by mass screening in children at 18 months of age. In the model diet used for treatment, 15% o...

journal_title：European journal of pediatrics

authors： Ohta T,Nakamura R,Ikeda Y,Hattori S,Matsuda I

更新日期：1993-11-01 00:00:00

abstract：UNLABELLED:Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder commonly prevalent in children worldwide including Thailand. However, there are very few studies thus far addressing risk factors for ASD in Thai children. This case-control study aims to investigate whether various risk factors es...

journal_title：European journal of pediatrics

authors： Khaiman C,Onnuam K,Photchanakaew S,Chonchaiya W,Suphapeetiporn K

更新日期：2015-10-01 00:00:00

abstract：:DiGeorge syndrome is a rare congenital anomaly with a wide range of clinical manifestations. This syndrome is usually associated with hypocalcaemia resulting from primary hypoparathyroidism. We report here a case of an 8-year-old boy with partial DiGeorge syndrome who presented initially with neonatal hypocalcaemia, b...

journal_title：European journal of pediatrics

authors： Hasegawa T,Hasegawa Y,Yokoyama T,Koto S,Asamura S,Tsuchiya Y

更新日期：1993-04-01 00:00:00

abstract：:Growth hormone (GH) responses to GRF (1 microgram/kg BW i.v.) were investigated. Comparison between GRF(1-40) and GRF(1-29)NH2 in 11 young adult volunteers gave identical results. One hundred and thirty-one children and adolescents (45 with idiopathic GHD) were tested with GRF (1-29)NH2. The maximal GH levels (max GH)...

journal_title：European journal of pediatrics

authors： Ranke MB,Gruhler M,Rosskamp R,Brügmann G,Attanasio A,Blum WF,Bierich JR

更新日期：1986-12-01 00:00:00

abstract：:The study material consisted of 251 newborn light-treated infants with rhesus haemolytic disease (RHD) caused by anti-D. 139 infants were treated with ordinary phototherapy (white single light) and 112 infants with intensive phototherapy (blue double light). An evaluation was made as to wheter the indications for earl...

journal_title：European journal of pediatrics

authors： Ebbesen F

更新日期：1980-01-01 00:00:00

abstract：:A large number of ventilation strategies are now available for the neonate. This review has focused on new information, that is, studies published since 2000 and the implication of their results for current clinical practice. Meta-analysis of randomised trials has demonstrated that assist control and synchronous inter...

journal_title：European journal of pediatrics

authors： Greenough A,Sharma A

更新日期：2007-10-01 00:00:00

abstract：:Two siblings with molybdenum cofactor deficiency are presented. They showed clinical, biochemical and neuroradiological features very similar to those of the few previously described cases. Difficulties in diagnosis are emphasised. ...

journal_title：European journal of pediatrics

authors： Hansen LK,Wulff K,Dorche C,Christensen E

更新日期：1993-08-01 00:00:00

abstract：:Co-trimoxazole is an effective antibacterial agent for the prophylaxis of urinary tract infection. Because experimental evidence raises the possibility that high-dose cotrimoxazole might interfere with normal somatic growth, the longitudinal growth and growth velocities were analysed in 114 girls receiving long-term, ...

journal_title：European journal of pediatrics

authors： Smellie JM,Preece MA,Paton AM

更新日期：1983-09-01 00:00:00

abstract：:Eight patients with the syndrome of benign paroxysmal vertigo of childhood are presented. This symptom complex is characterized by attacks of vertigo in young children combined with nystagmus, ataxia and transiently decreased vestibular function, but without impaired consciousness. Diagnostic and follow-up studies rev...

journal_title：European journal of pediatrics

authors： Koehler B

更新日期：1980-08-01 00:00:00

abstract：:Chronic lung disease of prematurity (CLD) remains a common cause of morbidity and mortality in preterm infants. Oxygen toxicity remains a major risk factor for the development of CLD and as a consequence the antioxidant status of CLD babies is a major focus of interest. In the present study, we determined whether asco...

journal_title：European journal of pediatrics

authors： Vyas JR,Currie A,Dunster C,Kelly FJ,Kotecha S

更新日期：2001-03-01 00:00:00

abstract：UNLABELLED:Fifty-two cases of childhood brucellosis which occurred in north-western Greece during the 15-year period 1979-1993, are reviewed. It is believed that they represent very closely the total incidence of the disease in the region which has a population of 100,000 children aged 0-14 years old. Brucellosis-affec...

journal_title：European journal of pediatrics

authors： Galanakis E,Bourantas KL,Leveidiotou S,Lapatsanis PD

更新日期：1996-01-01 00:00:00

abstract：UNLABELLED:A retrospective analysis of 218 bunk-bed accidents and a random sample survey with 991 family interviews were performed in order to establish guidelines for bunk-bed accident prevention. Falls from the top bed during sleep (35.1%) or while playing (34.4%) and falling off the ladder (23.2%) are the leading ca...

journal_title：European journal of pediatrics

authors： Mayr JM,Seebacher U,Lawrenz K,Pesendorfer P,Berghold A,Baradaran S

更新日期：2000-06-01 00:00:00