Abstract：
:The present study was done to evaluate the effect of short-term dietary therapy on 148 dyslipidaemic children (24 familial hypercholesterolaemia, 105 non-familial hypercholesterolaemia and 19 hypertriglyceridaemia), detected by mass screening in children at 18 months of age. In the model diet used for treatment, 15% of the total calories were obtained from protein, 27% from fat and 57% from carbohydrate. Cholesterol intake was set at < 200 mg/day and the ratio of polyunsaturated to saturated fatty acid (P/S ratio) was 1.2. When compared to the composition of the diet ingested by the dyslipidaemic children, only the P/S ratio changed from 0.7 to 1.2. During 12 months treatment, levels of total cholesterol, low density lipoproteins cholesterol and apoB decreased by 10%-15% in children with familial and non-familial hypercholesterolaemia. There was no significant change in the levels of high density lipoproteins. In 19 children with hypertriglyceridaemia, the intake of carbohydrate was limited to 55% of the total calories consumed and after 12 months of treatment, triglyceride levels reverted to normal. Throughout the study period, approximately 70% of the children on this dietary therapy were seen in our clinics every 3-6 months and physical development was within normal ranges. These results, taken together, indicate that dietary therapy can be effective for correcting dyslipidaemia, even in young children.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Ohta T,Nakamura R,Ikeda Y,Hattori S,Matsuda Idoi
10.1007/BF01957537subject
Has Abstractpub_date
1993-11-01 00:00:00pages
939-43issue
11eissn
0340-6199issn
1432-1076journal_volume
152pub_type
杂志文章abstract：:Neonatal acute respiratory distress syndrome (NARDS) reflects pulmonary surfactant dysfunction, and the usage of bovine surfactant (Calsurf) supplement may therefore be beneficial. To determine whether bovine surfactant given in NARDS can improve oxygenation and survival rate, we conducted a multicenter, randomized tr...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03821-2
更新日期：2020-10-21 00:00:00
abstract：:The renal function of 12 patients with non vitamin B12 responsive methylmalonic acidaemia has been investigated. Eight patients had reduced glomerular filtration rates, but the plasma creatinine concentration was only raised in those with values of less than 40 ml/min per 1.73 m2 surface area. The reduction in glomeru...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00444131
更新日期：1989-01-01 00:00:00
abstract：INTRODUCTION:Hypothermia at birth is strongly associated with mortality and morbidity in pre-term infants. BACKGROUND:A local audit showed limited effectiveness of occlusive wrapping in preventing admission hypothermia in very pre-term infants. Self-heating acetate gel mattresses were introduced as a result to prevent...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-009-1113-y
更新日期：2010-07-01 00:00:00
abstract：UNLABELLED:This study was conducted to determine if clinical features can predict the risk of intracranial injury (ICI) in pediatric closed head trauma. We enrolled 3,806 children under 16 years consecutively referred for acute closed head trauma to the paediatric emergency room of five Italian children's hospitals. Re...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s00431-005-0019-6
更新日期：2006-03-01 00:00:00
abstract：:Two siblings were found to be affected by long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, one of which died suddenly and unexpectedly on the 3rd day of life suffering from extreme hypoketotic hypoglycaemia. The younger sibling started to have feeding problems, lowered consciousness, and liver dysfunction at the...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01963564
更新日期：1991-01-01 00:00:00
abstract：:Exchange transfusion using a peripheral artery and vein was carried out 18 times in 17 newborn infants. The arteries use to withdraw blood were the radial [13], the ulnar [3] an the posterior tibial [2]. Infusion of blood was carried out simultaneously through a peripheral vein. There was no mortality or morbidity dir...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00443258
更新日期：1981-11-01 00:00:00
abstract：:Beckwith-Wiedemann syndrome is an overgrowth disorder characterized by neonatal macrosomia, abdominal wall defects, macroglossia, renal anomalies, organomegaly, hypoglycemia, and cancer predisposition. Hepatoblastoma is the second most frequent tumor and periodic serum alpha-fetoprotein (αFP) dosage is the cornerstone...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-011-1455-0
更新日期：2011-11-01 00:00:00
abstract：:Tonsillectomy is one of the commonest ENT paediatric procedures. Recovery is best achieved at home, and cost-effectiveness of the day case pathway is significant in tonsillectomy. This project scrutinised the local practice regarding the effectiveness of day case pathway in paediatric tonsillectomy in a large regional...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-018-3220-0
更新日期：2018-11-01 00:00:00
abstract：UNLABELLED:In patients with propionic acidaemia (PA), the increased intracellular concentration of propionyl-CoA leads to a relative abundance of odd-numbered long-chain fatty acids (OLCFAs) in body lipids. We investigated the relative amount of OLCFA in erythrocyte membrane lipids over a period of 1-8 years in five pa...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050010
更新日期：2000-01-01 00:00:00
abstract：:Plasma vitamin E levels were determined serially in preterm infants surviving respiratory distress syndrome (RDS) and in premature infants without RDS (control). Vitamin E intakes of the RDS and control infant group were not significantly different. The results of the study show that preterm infants surviving RDS have...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00446056
更新日期：1986-08-01 00:00:00
abstract：:It is known that the 5%-10% of adults infected with hepatitis B virus (HBV) develop a chronic infection and that HBV infection acquired at birth by an hepatitis B surface antigen (HBsAg)/hepatitis B "e" antigen (HBeAg)-positive mother almost invariably leads to chronic infection. Little information is, however, availa...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01954381
更新日期：1992-03-01 00:00:00
abstract：UNLABELLED:Dynamic processes are of great interest in the study of lipid and fatty acid metabolism. Their in vivo investigation is now possible with the use of stable isotope tracers and the available sensitive analytical technology. We present some examples demonstrating the assessment of lipid oxidation as well as mo...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/pl00014276
更新日期：1997-08-01 00:00:00
abstract：:A 9-year-old girl presented with a red scaly rash confined to sun-exposed areas which started at 2 years of age and had the appearance of pellagra. Investigation of urinary tryptophan metabolites following an oral tryptophan load, showed increased excretion of kynurenine and kynurenic acid but reduced excretion of 3-h...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01958432
更新日期：1991-05-01 00:00:00
abstract：:Adolescence obesity and depression are increasingly prevalent and are associated with various health complications. The aim of this study was to examine the association between weight status (normal weight, overweight, and obese) and depressive symptoms in adolescents and to explore the probable mediators, including o...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1753-1
更新日期：2012-08-01 00:00:00
abstract：:This is apparently the first report on connatal hemihypertrophy with malignant pheochromocytoma. The coincidence of hemihypertrophy with other diseases, particularly neuroectodermal dysplasias on the one hand and the frequent association of neuroectodermal dysplasias with pheochromocytoma on the other, are emphasized....
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00481506
更新日期：1976-07-12 00:00:00
abstract：:We report what we believe to be the first case of simultaneous infection by Toxoplasma gondii and cytomegalovirus in a newborn. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00496426
更新日期：1988-05-01 00:00:00
abstract：:Positional plagiocephaly (PP) denotes flattening of the skull that occurs frequently in healthy infants. Aim of this study was to estimate the prevalence of positional plagiocephaly and to identify the risk factors in a cohort of healthy infants in order to help prevention of PP. In a prospective design, all healthy f...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-018-3212-0
更新日期：2018-10-01 00:00:00
abstract：:There is far-reaching consent in the literature that public and consensual agreements on the basics of the different aspects of medical ethics are inalienable before the instigation of any innovative transplant procedure. In the case of a certain method and/or of an individual patient, however, the ultimate ethical ev...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02125808
更新日期：1992-01-01 00:00:00
abstract：:This study gives, for the first time, an estimate of the incidence and the cost of rotavirus infection in day care centers in Lyon, France. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s00431-006-0187-z
更新日期：2006-12-01 00:00:00
abstract：:A new method for the detection of hyperammonemia, using a kit based on the principle of microdiffusion of ammonia, is described. The method requires only one drop of blood and takes only 15 min to complete. Experiments for recovery and reproducibility were satisfactory, and good correlation was obtained when compared ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442347
更新日期：1979-02-08 00:00:00
abstract：UNLABELLED:Self-medication is a common event. To use drugs correctly, a basic knowledge about drugs is required. Poor data are available about adults' drug knowledge. Furthermore, adolescents' basic drug knowledge has not been investigated. This study was designed in order to explore adolescents' drug use and knowledge...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310000503
更新日期：2000-08-01 00:00:00
abstract：BACKGROUND:The tuberculin skin test (TST) is the most useful method for the diagnosis of tuberculosis (TB). There is no evidence about the effect of bacillus Calmette-Guerin (BCG) vaccine on the interpretation of TST results. OBJECTIVE:The aim of this study was to evaluate TST results in a population of immigrants and...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1783-8
更新日期：2012-11-01 00:00:00
abstract：:WHO-Europe's goal is to eliminate measles and rubella by 2010 which will require a coverage rate of 95% for both MMR-vaccine doses. Belgian recommendations include a first MMR vaccine at 12 months and a second at 10-12 years of age. To survey MMR vaccination coverage, EPI two-stage random cluster samples of 1,500 todd...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0652-3
更新日期：2008-10-01 00:00:00
abstract：:Presentation of cystic fibrosis (CF) with an acrodermatitis enteropathica-like skin rash, anemia, and hypoproteinemia without pulmonary disease is rarely reported before. We describe an 11-month-old boy with rash and edema as the presenting signs of cystic fibrosis. The interesting additional finding in our patient wa...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-011-1447-0
更新日期：2011-10-01 00:00:00
abstract：UNLABELLED:Acid reflux and/or oesophagitis may be responsible for inconsolable crying in infants. We evaluated prospectively the presence of acid reflux disease, oesophagitis and the accuracy of pH monitoring in the prediction of oesophagitis in a population of irritable infants. A 24-h oesophageal pH monitoring with a...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-004-1403-3
更新日期：2004-06-01 00:00:00
abstract：UNLABELLED:Adolescents are becoming more independently responsible for their medication regimen; therefore, adolescence is a crucial period to address medication beliefs, as many of the beliefs may persist into adulthood and can impair adherence and willingness to continue a prescribed therapy. Within this study, we ai...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-2211-4
更新日期：2014-04-01 00:00:00
abstract：:We report a patient with the characteristic features of the brittle cornea syndrome, a rare, autosomal recessively inherited disorder, namely brittle corneae, blue sclerae, and red hair. The patient also showed joint hyperextensibility, a soft skin, and dysplastic auricles with unusually soft cartilage. Phenotypically...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01959396
更新日期：1990-04-01 00:00:00
abstract：:There are three forms of high frequency ventilation, high frequency jet ventilation (HFJV, up to 400/min), high frequency oscillation (HFO, up to 40 Hz), and high frequency positive pressure ventilation (HFPPV, rates between 60 and 150/min). The first two forms of ventilation are still experimental and have been used ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441591
更新日期：1987-09-01 00:00:00
abstract：:A bulging fontanelle due to benign increased intracranial pressure is not generally recognized as a manifestation of nutritional rickets but should be considered in the appropriate clinical setting. Two children who we saw presented with bulging anterior fontanelles were found to have pseudotumor cerebri in associatio...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442144
更新日期：1985-01-01 00:00:00
abstract：:Olfactory function in children is most commonly evaluated using the odour identification test despite the fact that it is difficult to properly name odorants for young children. The goal of this study was to evaluate the pleasantness rating of odorants by children. The participants were 182 healthy children: the first...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03778-2
更新日期：2020-08-14 00:00:00
