Abstract：
:Olfactory function in children is most commonly evaluated using the odour identification test despite the fact that it is difficult to properly name odorants for young children. The goal of this study was to evaluate the pleasantness rating of odorants by children. The participants were 182 healthy children: the first group included 63 girls and 59 boys (aged 6-7) and the second included 31 girls and 29 boys (aged 11-12). We assessed olfaction using (1) standard method of odorant identification using a U-Sniff test and (2) classifying the hedonic tone of the odorants into 5 categories. The identification test's median differed in younger and older groups of children; the median was 8 and 10 respectively (p < 0.01). The unpleasant hedonic tones were butter, fish and onion. The pleasant hedonic tones were apple, orange and peach. The younger usually categorised hedonic tones as pleasant, compared with the older children, who categorised the odorant's hedonic tones more often as neutral (p < 0.01).Conclusion: This study demonstrated that older children are able to identify odours better than younger ones. The categorisation of hedonic tones differed depending on the subject's age. The younger children tended to categorise odorants as being pleasant and older children as neutral. What is Known: • The test of odour identification is the most popular because it is reliable, practical, rapid and commercially available. • The ability to identify odours improves with age in children. What is New: • The categorisation of hedonic tones differs depending on age. The older children categorise odorants as being neutral significantly more often than younger children do.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Brothánková P,Vodička J,Bažant Jdoi
10.1007/s00431-020-03778-2subject
Has Abstractpub_date
2020-08-14 00:00:00eissn
0340-6199issn
1432-1076pii
10.1007/s00431-020-03778-2pub_type
杂志文章abstract：:In five L-thyroxine-substituted hypothyroid children with partial epilepsy serum total thyroxine (T4) and free T4 (FT4) significantly (P less than 0.01) decreased following 2 months of carbamazepine (CBZ) administration (20 mg/kg per BW per day) from mean (+/- SD) values of 12.7 +/- 1.1 micrograms/dl and 15.5 +/- 1.8 ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441860
更新日期：1986-04-01 00:00:00
abstract：:Inappropriate use of antibiotics in human and animal is one of the causes of antimicrobial resistance. This study evaluates the prevalence and predictors of antibiotic use among pediatric patients visiting the Emergency Department (ED) in Malaysia. A retrospective cross-sectional study was conducted in the ED of a ter...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-019-03560-z
更新日期：2020-05-01 00:00:00
abstract：UNLABELLED:Fifty-two cases of childhood brucellosis which occurred in north-western Greece during the 15-year period 1979-1993, are reviewed. It is believed that they represent very closely the total incidence of the disease in the region which has a population of 100,000 children aged 0-14 years old. Brucellosis-affec...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02115616
更新日期：1996-01-01 00:00:00
abstract：:A 17-year-old patient suffering from Crohn disease (CD) and liver cirrhosis is presented. At an advanced stage of the disease, he died of a concomitant urosepsis. Autopsy showed that the liver cirrhosis was caused by sclerosing cholangitis. This very rare complication of CD in adolescence is discussed. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02072206
更新日期：1991-06-01 00:00:00
abstract：:Twenty-six children with cerebral palsy were examined with respect to structural asymmetry of the mouth. In 19 children there were clear cut correlations between symmetry/asymmetry of voluntary function and the oral findings. Patients with symmetrical patterns of movements had symmetrical dentition, while in those wit...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441639
更新日期：1980-12-01 00:00:00
abstract：:A South African family with autosomal dominant split hand, split foot (SHSF) malformation has been studied. The pedigree was unusual in that three unaffected siblings with normal parents had each produced affected offspring. New mutation, germinal mosaicism and autosomal recessive inheritance are unlikely. Possible ex...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442225
更新日期：1988-02-01 00:00:00
abstract：:Hypoparathyroidism is one of the recognized causes of late-onset neonatal hypocalcemia. Maternal hypercalcemic hyperparathyroidism has been shown to suppress fetal parathyroid glands, causing transient neonatal hypoparathyroidism. We report two siblings (6 years apart) with transient hypoparathyroidism presented with ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0528-6
更新日期：2008-04-01 00:00:00
abstract：UNLABELLED:Severe head injuries in children (under 15 years of age) have many features that differentiate them from head injuries in adults. In such cases, non-surgical treatment cannot always prevent fatal herniation. We report on seven cases of children with severe head injury, presenting with decorticate posturing a...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-001-0864-x
更新日期：2002-02-01 00:00:00
abstract：:A girl, now three years old, is reported, in whom at the age of 5 months the diagnosis of 3-HMG-CoA lyase deficiency was established. The characteristic excretion pattern consisted of 3-HMG, 3-CH3-glutaconic acid, 3-CH3-glutaric acid and 3-HIVA. Activity of 3-HMG-CoA lyase in leucocytes was very low. She had compensat...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442334
更新日期：1982-02-01 00:00:00
abstract：:The use of supra-physiological, exogenous corticosteroids in pregnancy may lead to neonatal adrenal suppression. We report on a single-center, case series study carried out between 2006 and 2014, which included all newborns (n = 16) of mothers using prednisolone ≥10 mg/day during pregnancy. Newborns were routinely ass...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-2949-1
更新日期：2017-08-01 00:00:00
abstract：:Congenital diaphragmatic eventration (CDE) and congenital diaphragmatic hernia (CDH) with or without hernia sac are three different types of congenital diaphragmatic malformations, which this study evaluates. All surgically treated patients with CDE or Bochdalek type CDH between 2000 and 2016 were included in this ret...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03576-w
更新日期：2020-06-01 00:00:00
abstract：INTRODUCTION:Impaired vitamin K status in cystic fibrosis (CF) has been considered as a newly emerged pathogenetic factor for reduced bone mineral density (BMD). OBJECTIVES:Our aim was to evaluate the effectiveness of vitamin K supplementation in managing bone formation abnormalities in children and adolescents with C...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-006-0132-1
更新日期：2006-08-01 00:00:00
abstract：UNLABELLED:The aim of this study was to evaluate to what extent serum vitamins A and E cystic fibrosis are affected by the underlying disease, pancreatic sufficiency or insufficiency, meconium ileus, nutritional status, age and treatment (enzyme and vitamin supplementation). Serum vitamin A and E levels were determined...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02002713
更新日期：1996-04-01 00:00:00
abstract：UNLABELLED:Over the last few years, the importance of paediatric stroke has become more and more evident; however, there is still little known about long-term neurological and especially neuropsychological outcome of these children. By retrospective chart review, questionnaire and clinical examination with structured i...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-003-1357-x
更新日期：2004-04-01 00:00:00
abstract：:The name of the co-author Wendy J. Ungar was inadvertently omitted on the original published article. Her name and affiliation have now been added to the author list. ...
journal_title：European journal of pediatrics
pub_type： 已发布勘误
doi：10.1007/s00431-019-03526-1
更新日期：2020-02-01 00:00:00
abstract：:An 8-year-old boy with an hepatic form of Wilson disease was treated with oral zinc sulphate as the primary and sole therapy. After 4 months, liver function had dramatically improved, and the parameters characterizing copper metabolism had also normalized. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441526
更新日期：1989-06-01 00:00:00
abstract：UNLABELLED:Cleidocranial dysplasia (CCD; MIM 119600) is an autosomal dominant skeletal dysplasia characterised by hypoplastic clavicles, patent fontanelles, short stature, tooth anomalies and other variable skeletal changes. Different mutations of the RUNX2/CBFA1 gene (MIM 600211) have been detected in patients with CC...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-002-0977-x
更新日期：2002-11-01 00:00:00
abstract：:In a five-year-old girl with congenital hepatic fibrosis raised erythrocyte sedimentation rate and serum gammaglobulins were noted for 3 years. Needle liver biopsy showed histological features of cholangitis and Klebsiella oxytoca was cultured from a liver biopsy specimen. Antibiotic treatment resulted in normalizatio...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01377359
更新日期：1982-11-01 00:00:00
abstract：UNLABELLED:Neutrophils are an essential component of the human host defence system against infection. Recombinant human granulocyte colony-stimulating factor induces neutrophilia and enhances effector functions of mature neutrophils. Since the biological effects of granulocyte colony-stimulating factor (G-CSF) are medi...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310051129
更新日期：1999-06-01 00:00:00
abstract：:Prolonged emergency department (ED) length of stay (LOS) is used as a proxy for ED overcrowding and is associated with adverse outcomes of patients requiring therapy and reduced patient satisfaction. Our aim was to identify and quantify variables which affect ED-LOS. Patients admitted to the pediatric ED of a large re...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-2879-y
更新日期：2017-05-01 00:00:00
abstract：:Failure to thrive, feeding difficulties, variable forms of infantile epilepsy or psychomotor developmental delay and hypotonia were the most frequent clinical disease presentations in eight children with combined oxidative phosphorylation enzyme complex deficiencies carrying mutations in the polymerase gamma (POLG1) g...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-006-0234-9
更新日期：2007-03-01 00:00:00
abstract：:Paraneoplastic manifestations are signs and symptoms observed in patients with cancer, distant from the tumour or its metastases and not caused by invasion, obstruction or bulk mass. In children with cancer, paraneoplastic manifestations are rare and distinct from those observed in adults. Knowledge about paraneoplast...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF01972883
更新日期：1994-11-01 00:00:00
abstract：:Recombinant human erythropoietin was given to eight children and adolescents with stable chronic renal failure in the predialysis state. The hormone was administered subcutaneously, twice weekly for 12 weeks, at a starting dose of 50 U/kg per week. The dosage was adapted every 4th week. Target haemoglobin was 10.5-11....
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01959224
更新日期：1994-02-01 00:00:00
abstract：:We describe the natural history of the RTSII phenotype in a 7-year-old boy who developed intrauterine and postnatal growth retardation, failure to thrive and persisting diarrhoea. The growth hormone stimulation test identified an isolated growth hormone deficiency. Since infancy, the patient manifested skin lesions ch...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0447-6
更新日期：2008-02-01 00:00:00
abstract：:Severe hand, foot, and mouth disease (HFMD) is likely to develop critical complications such as brainstem encephalitis, acute pulmonary edema, and circulatory failure, which cause child mortality during outbreaks. This study aims to investigate factors that predict the severity of HFMD. One hundred sixteen in-patient ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-1939-1
更新日期：2013-05-01 00:00:00
abstract：:We report a 13 year-old girl with manifestations strikingly reminiscent of the tricho-rhino-phalangeal (TRP) II or Langer-Giedion syndrome. A terminal deletion of 8q must be assumed to be the cause of her condition till proven otherwise. A similar chromosome abnormality should be searched for (blindly) in other cases ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441586
更新日期：1980-03-01 00:00:00
abstract：UNLABELLED:Two patients are described with acute collapse caused by pericardial effusion following central venous catheterisation. Echocardiography during resuscitation allowed prompt identification and management. CONCLUSION:Pericardial effusion should be considered in any baby experiencing acute deterioration with a...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310100828
更新日期：2001-12-01 00:00:00
abstract：:Lemierre syndrome, also known as postanginal sepsis, is a severe complication of an acute oropharyngeal infection that results in septic thrombophlebitis of the ipsilateral internal jugular vein with subsequent septicemia, often complicated by metastatic infections (Syed et al., Laryngoscope 117:1605-1610, 2007). We p...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-009-1134-6
更新日期：2010-04-01 00:00:00
abstract：:We report on a newborn infant with complex congenital heart disease (CHD) featuring double outlet right ventricle and hypoplastic left ventricle who had postductal oxygen saturation well above 95% and thus eluded pulse oximetry screening for CHD. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-006-0283-0
更新日期：2007-06-01 00:00:00
abstract：:Primary ciliary dyskinesia (PCD) is an inherited disease related to ciliary dysfunction, with heterogeneity in clinical presentation and in ciliary ultrastructural defect. Our study intended to determine if there are phenotypic differences in patients with PCD based on ciliary ultrastructural abnormality. In this retr...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-1996-5
更新日期：2013-08-01 00:00:00
