Abstract:
OBJECTIVES:This study evaluated the effect of the administration of pre-operative dexamethasone on tooth sensitivity stemming from in-office bleaching. MATERIALS AND METHODS:A triple-blind, parallel-design, randomized clinical trial was conducted on 70 volunteers who received dexamethasone or placebo capsules. The drugs were administered in a protocol of three daily 8-mg doses of the drug, starting 48 h before the in-office bleaching treatment. Two bleaching sessions with 37.5% hydrogen peroxide gel were performed with a 1-week interval. Tooth sensitivity (TS) was recorded on visual analog scales (VAS) and numeric rating scales (NRS) in different periods up to 48 h after bleaching. The color evaluations were also performed. The absolute risk of TS and its intensity were evaluated by using Fisher's exact test. Comparisons of the TS intensity (NRS and VAS data) were performed by using the Mann-Whitney U test and a two-way repeated measures ANOVA and Tukey's test, respectively. RESULTS:In both groups, a high risk of TS (Dexa 80% x Placebo 94%) was detected. No significant difference was observed in terms of TS intensity. A whitening of approximately 3 shade guide units of the VITA Classical was detected in both groups, which were statistically similar. CONCLUSIONS:It was concluded that the administration pre-operatively of dexamethasone, in the proposed protocol, does not reduce the incidence or intensity of bleaching-induced tooth sensitivity. CLINICAL RELEVANCE:The use of dexamethasone drug before in-office bleaching treatment does not reduce incidence or intensity of tooth sensitivity. CLINICAL TRIAL REGISTRATION NUMBER:NCT02956070.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
da Costa Poubel LA,de Gouvea CVD,Calazans FS,Dip EC,Alves WV,Marins SS,Barcelos R,Barceleiro MOdoi
10.1007/s00784-018-2452-8subject
Has Abstractpub_date
2019-01-01 00:00:00pages
435-444issue
1eissn
1432-6981issn
1436-3771pii
10.1007/s00784-018-2452-8journal_volume
23pub_type
杂志文章,随机对照试验abstract:OBJECTIVES:Targeted modifications of the bulk implant surfaces using bioactive agents provide a promising tool for improvement of the long-term bony and soft tissue integration of dental implants. In this study, we assessed the cellular responses of primary human gingival fibroblasts (HGF) to different surface modifica...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1784-5
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:The main purpose of this prospective, double-blind, randomized study was to evaluate anaesthetic parameters, postoperative analgesia and vasoactive properties of levobupivacaine and bupivacaine for lower third molar surgery. MATERIAL AND METHODS:Sixty patients (ASA I) were scheduled for lower third molar su...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1114-0
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to compare the onset, success rate, injection pain, and post-injection pain of mental/incisive nerve block (MINB) with that of inferior alveolar nerve block (IANB) using 4% articaine in mandibular premolars with symptomatic irreversible pulpitis. The accuracy of electrical pulp test...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-018-2500-4
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to quantify the blue light that passes through different incremental thicknesses of bulk fill in comparison to conventional resin-based composites (RBCs) and to relate it to the induced mechanical properties. MATERIALS AND METHODS:Seven bulk fill, five nanohybrid and two flowable R...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1177-y
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:Bisphosphonates and denosumab are antiresorptive drugs used for the treatment of osteoporosis and oncological tumors. A severe side effect is osteonecrosis of the jaw. Monocyte/macrophage dysfunction is considered to play a distinct role in osteonecrosis. THP-1 monocytic cells were used in this study to eluc...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1358-3
更新日期:2015-07-01 00:00:00
abstract::The goal of this investigation was to evaluate the effect of postoperative exposure of two different bioresorbable membranes on the guided tissue regeneration (GTR) healing results compared to nonexposed sites. In each of 25 patients one pair of contralateral intrabony lesions was treated either with polylactic acid (...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050021
更新日期:1997-09-01 00:00:00
abstract::The purpose of this 4-day plaque regrowth study was to assess the effect of N-chlorotaurine (NCT) mouth rinses on plaque inhibition and plaque vitality. Eighty volunteers participated in this investigator-blind, randomized, clinical controlled study in parallel groups. No oral hygiene was permitted except rinsing with...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-008-0207-7
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:The aim of this article is to compare the influence of surface treatment on the integration (at 2, 4 and 8 weeks) of 120 dental implants inserted in 60 tibiae of rabbits. MATERIALS AND METHODS:Four different surfaces were double-blind tested: blasted, acid-etched and discrete crystal deposition (DCD) (group ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1241-2
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to investigate the caries-preventive effect of newly developed fluoride and fluoride-free toothpastes specially designed for erosion prevention. The hypothesis was that these products might also show superior caries-inhibiting effect than regular fluoride toothpastes, since they were...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1789-0
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:The corona disease (COVID-19) is developing into one of the greatest challenges for healthcare professionals around the world. In this article, we report the detailed actions taken in the Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians-University (LMU), Munich...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03440-z
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:To investigate the relationship of the irradiance-beam-profile areas from six different light-curing units (LCUs) with the degree of conversion (DC), microhardness (KH), and cross-link density (CLD) throughout a resin-based composite (RBC) cured at two clinically relevant distances, and to explore the correl...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02831-1
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:This study aimed to assess self- and proxy-rated changes in the oral health-related quality of life (OHRQoL) in adult patients with intellectual disabilities after dental treatment in general anesthesia. METHODS:The OHRQoL in 52 adult patients with intellectual and developmental disabilities was assessed pr...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02820-4
更新日期:2019-10-01 00:00:00
abstract::The alveolar cleft in patients with clefts of lip, alveolus and palate (CLAP) is usually reconstructed with an autologous bone graft. Harvesting of autologous bone grafts is associated with more or less donor site morbidity. Donor site morbidity could be eliminated if bone is fabricated by growth factor-aided tissue e...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s00784-011-0547-6
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Interleukin 8 (IL-8) is a pro-angiogenic, pro-inflammatory mediator that belongs to the family of chemokines. Due to its pro-angiogenic characteristic, it may play a vital role in tumour angiogenesis and progression. OBJECTIVES:This study was designed to estimate the levels of salivary IL-8 in oral precance...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0723-3
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the prevalence, clinical features, and risk factors of dentin hypersensitivity (DH) in a Brazilian population. MATERIALS AND METHODS:300 patients at the Dentistry Clinic of the University of São Paulo participated in this study. The subjects completed a questionnaire regarding their personal inf...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1008-1
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Long-term culture system is used to prevent the impediment of insufficient cells and is good for low starting materials such as dental pulp or periodontal ligament. In general, although cell viability and functionality are the most common aspects taken into consideration in culturing cells for...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1497-1
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:This animal study was conducted to evaluate the osteocyte index in the peri-implant bone around immediately restored implants under static lateral overload. MATERIAL AND METHODS:Seven mongrel dogs received three implants on each side of the mandible. Forty-two implants were distributed into three groups (14...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03662-1
更新日期:2020-11-05 00:00:00
abstract:OBJECTIVES:Evaluate the bone remodeling during orthodontic movement with corticotomy when submitted to low-intensity electrical stimulation application (microcurrent-MC) and low-level laser therapy (LLLT). MATERIAL AND METHODS:One hundred and fifty Wistar rats were divided into the following 5 groups: (C) submitted to...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02845-9
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:The main goal of the present study was to compare the biomechanical stability of locking plates and conventional miniplate combinations in human mandibles reconstructed with fibular grafts. MATERIALS AND METHODS:A specially developed and well-proven testing device reproduced the in vivo loading conditions o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1105-1
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:C-shaped root canal configuration is an unusual root canal morphology and one of the most often anatomical variations in root canal systems of second mandibular molars. The purpose of this study was to assess the prevalence, symmetry and configuration of C-shaped canals in first and second mandibular molars ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1993-y
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVES:For well-defined deep (> 2/3 dentin extension) carious lesions, selective (SE) or stepwise (SW) carious tissue removals have been recommended, while there is limited comparative evidence for both. We compared SE and SW over 24 months in a randomized controlled trial. METHODS:A two-arm superiority trial was ...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-020-03536-6
更新日期:2021-02-01 00:00:00
abstract:OBJECTIVE:To evaluate the systemic and periodontal conditions, as well as the determinants of health in pregnant women with and without obesity/overweight during the second and third trimesters of pregnancy and after delivery. MATERIALS AND METHODS:In the second trimester (T1), 93 pregnant women were divided into two ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02932-x
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to measure modifications of mastication after immediate loading full-arch prosthesis (ILFAP) rehabilitation. MATERIALS AND METHOD:Fourteen patients were observed before and 6 months after ILFAP rehabilitation when masticating two natural, standardized foods (peanut and carrot) and three mode...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-012-0787-0
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVES:The clinical standard for alveolar cleft osteoplasty is augmentation with autologous bone being available in limited amounts and might be associated with donor site morbidity. The aim of the present study was the creation of tissue-engineered bone grafts and their in vivo evaluation regarding their potential...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2050-1
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:This study investigated the antibacterial properties and micro-hardness of polyacrylic acid (PAA)-coated copper iodide (CuI) nanoparticles incorporated into glass ionomer-based materials, and the effect of PAA-CuI on collagen degradation. MATERIALS AND METHODS:PAA-CuI nanoparticles were incorporated into gl...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1799-y
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess postoperative pain in a prospective randomized clinical trial comparing two groups, using the Reciproc® system in one group and the ProTaper® rotary system in the other. MATERIAL AND METHODS:The study included 78 male patients, aged 18-64 years (mean age of 26 years), wit...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-015-1692-0
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:This study aims to investigate the additional influence of multiple applications of antimicrobial photodynamic therapy (aPDT) in smokers with chronic periodontitis. MATERIALS AND METHODS:Twenty smokers with chronic periodontitis were treated in a split-mouth design study with aPDT adjunct to Scaling and Roo...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-018-2740-3
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to validate a standardized pragmatic approach to manage new oral anticoagulants (NOACs) in patients who undergo dental extractions. MATERIALS AND METHODS:This prospective case-control study in patients undergoing dental extraction included 26 patients (mean age 76 years, 57% male) ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-2010-1
更新日期:2017-09-01 00:00:00
abstract:AIM:The aim of this study was to compare the effectiveness of 2% articaine and 2% lignocaine in achieving adequate anesthesia in children between the age group of 6-13 years using inferior alveolar nerve block. METHODS:A triple blinded randomized controlled trial was conducted in 180 participants (90 patients- 2% arti...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-018-2775-5
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:The aim of this retrospective study was to evaluate the influence of various predictors on healing outcomes after direct pulp capping (DPC) using either mineral trioxide aggregate (MTA) or calcium hydroxide (CH) as a pulp-dressing agent. MATERIALS AND METHODS:The present study included 172 mature asymptomat...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1798-z
更新日期:2017-01-01 00:00:00