On the contributing role of the transmembrane domain for subunit-specific sensitivity of integrin activation.

abstract：:Infection with Mycobacterium ulcerans causes Buruli Ulcer, a neglected tropical disease. Mosquito vectors are suspected to participate in the transmission and environmental maintenance of the bacterium. However, mechanisms and consequences of mosquito contamination by M. ulcerans are not well understood. We evaluated ...

journal_title：Scientific reports

authors： Hoxmeier JC,Thompson BD,Broeckling CD,Small P,Foy BD,Prenni J,Dobos KM

更新日期：2015-03-18 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Zhang H,Li G,Su B,Deng M,Liu YX,Gu YC,Wang QM

更新日期：2018-03-06 00:00:00

abstract：:Real-time Precise Point Positioning (PPP) technique is being widely applied for providing precise positioning services with the significant improvement on satellite precise products accuracy. With the rapid development of the multi-constellation Global Navigation Satellite Systems (multi-GNSS), currently, about 80 nav...

journal_title：Scientific reports

authors： Gao Z,Shen W,Zhang H,Niu X,Ge M

更新日期：2016-07-29 00:00:00

abstract：:A novel polyphenolic natural product, galewone, with undescribed carbon skeleton, was isolated as a racemate from the culture of Daldinia eschscholzii IFB-TL01, a fungus obtained from the mantis (Tenodera aridifolia) gut. The galewone structure was elucidated by a combination of MS and NMR spectra, and substantiated b...

journal_title：Scientific reports

authors： Zhang AH,Jiang N,Wang XQ,Tan RX

更新日期：2019-10-04 00:00:00

abstract：:Multidisciplinary applications of four-coordinate boron(III) complexes make them very attractive and challenging research field in chemistry, biology and material sciences. The dual role played by boron atom in stabilising the chelate ligand and enhancing the π-conjugation makes them very useful as luminescent materia...

journal_title：Scientific reports

authors： Sadu VS,Bin HR,Lee DM,Lee KI

更新日期：2017-03-21 00:00:00

abstract：:The determinants of Xpert MTB/RIF sensitivity, a widely used PCR test for the diagnosis of tuberculosis (TB) are poorly understood. We compared culture time-to-positivity (TTP; a surrogate of bacterial load), MTB/RIF TB-specific and internal positive control (IPC)-specific C(T) values, and clinical characteristics in ...

journal_title：Scientific reports

authors： Theron G,Peter J,Calligaro G,Meldau R,Hanrahan C,Khalfey H,Matinyenya B,Muchinga T,Smith L,Pandie S,Lenders L,Patel V,Mayosi BM,Dheda K

更新日期：2014-07-11 00:00:00

abstract：:This study aims to evaluate the necessity of urgent neuroimaging for emergency admissions exhibiting symptomatology of profound hyponatremia. We retrospectively analyzed the medical records of all patients admitted to the emergency room of the University Hospital Münster from 2010 to 2014 with a serum sodium value < 1...

journal_title：Scientific reports

authors： Bokemeyer A,Dziewas R,Wiendl H,Schwindt W,Bicsán P,Kümpers P,Pavenstädt H

更新日期：2017-05-16 00:00:00

abstract：:Systemic lupus erythematosus (SLE) patients are vulnerable to infections. We aim to explore the approach to differentiate active infection from disease activity in pediatric SLE patients. Fifty pediatric SLE patients presenting with 185 clinical visits were collected. The associations between both clinical and laborat...

journal_title：Scientific reports

authors： Luo KL,Yang YH,Lin YT,Hu YC,Yu HH,Wang LC,Chiang BL,Lee JH

更新日期：2020-11-16 00:00:00

abstract：:Heavy metals are environmental pollutants affect the integrity and distribution of living organisms in the ecosystem and also humans across the food chain. The study targeted the removal of copper (Cu2+) from aqueous solutions, depending on the biosorption process. The bacterial candidate was identified using 16S rRNA...

journal_title：Scientific reports

authors： Ghoniem AA,El-Naggar NE,Saber WIA,El-Hersh MS,El-Khateeb AY

更新日期：2020-06-11 00:00:00

abstract：:In southeastern China (SEC), the precipitation amount produced by the East Asian summer monsoon (EASM) is almost equivalent to that during the non-summer monsoon (NSM) period, both of them significantly affecting agriculture and socioeconomy. Here, we present a seasonally-resolved stalagmite δ18O record (δ18Os) for th...

journal_title：Scientific reports

authors： Zhang H,Cheng H,Spötl C,Cai Y,Sinha A,Tan L,Yi L,Yan H,Kathayat G,Ning Y,Li X,Zhang F,Zhao J,Edwards RL

更新日期：2018-08-17 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Lin RT,Lin CK,Christiani DC,Kawachi I,Cheng Y,Verguet S,Jong S

更新日期：2018-03-12 00:00:00

abstract：:Innate immunity is induced when pathogen-associated molecular patterns (PAMPs) bind host pattern recognition receptors (PRRs). Polyinosinic:polycytidylic acid [poly(I:C)] is a synthetic analogue of viral dsRNA that acts as a PAMP, inducing type I interferons (IFNs) in vertebrates. In the present study, the immunostimu...

journal_title：Scientific reports

authors： Alkie TN,de Jong J,Jenik K,Klinger KM,DeWitte-Orr SJ

更新日期：2019-09-20 00:00:00

abstract：:Melatonin has antioxidant and scavenger effects in the cellular antioxidant system. This research investigated the protective effects and underlying mechanisms of melatonin action in porcine somatic cell nuclear transfer (SCNT) embryos. The results suggested that the developmental competence of porcine SCNT embryos wa...

journal_title：Scientific reports

authors： Liang S,Jin YX,Yuan B,Zhang JB,Kim NH

更新日期：2017-09-11 00:00:00

abstract：:IgA nephropathy (IgAN) is the most prevalent among primary glomerular diseases worldwide. Although our understanding of IgAN has advanced significantly, its underlying biology and potential drug targets are still unexplored. We investigated a combinatorial approach for the analysis of IgAN-relevant -omics data, aiming...

journal_title：Scientific reports

authors： Krochmal M,Cisek K,Filip S,Markoska K,Orange C,Zoidakis J,Gakiopoulou C,Spasovski G,Mischak H,Delles C,Vlahou A,Jankowski J

更新日期：2017-08-22 00:00:00

abstract：:The significant risk of disease transmission has selected for effective immune-defense strategies in insect societies. Division of labour, with individuals specialized in immunity-related tasks, strongly contributes to prevent the spread of diseases. A trade-off, however, may exist between phenotypic specialization to...

journal_title：Scientific reports

authors： Cini A,Bordoni A,Cappa F,Petrocelli I,Pitzalis M,Iovinella I,Dani FR,Turillazzi S,Cervo R

更新日期：2020-06-02 00:00:00

abstract：:Fat deposition of beef cattle varies between breeds. However, the regulation mechanism is still not elucidated completely at molecular level. In the present study, we comparatively analyzed transcriptome of subcutaneous adipose tissue between Wagyu and Holstein cattle with a significant difference in fat deposition to...

journal_title：Scientific reports

authors： Huang W,Guo Y,Du W,Zhang X,Li A,Miao X

更新日期：2017-07-13 00:00:00

abstract：:Nanoscale real-time molecular sensing requires large signal enhancement, small background, short detection time and high spectral resolution. We demonstrate a new vibrational spectroscopic technique which satisfies all of these conditions. This time-resolved surface-enhanced coherent anti-Stokes Raman scattering (tr-S...

journal_title：Scientific reports

authors： Voronine DV,Sinyukov AM,Hua X,Wang K,Jha PK,Munusamy E,Wheeler SE,Welch G,Sokolov AV,Scully MO

更新日期：2012-01-01 00:00:00

abstract：:Abdominal aortic aneurysm (AAA) is a leading cause of sudden death in aged people. Activation of ubiquitin proteasome system (UPS) plays a critical role in the protein quality control and various diseases. However, the functional role of UPS in AAA formation remains unclear. In this study, we found that the proteasome...

journal_title：Scientific reports

authors： Ren H,Li F,Tian C,Nie H,Wang L,Li HH,Zheng Y

更新日期：2015-10-28 00:00:00

abstract：:Monitoring one's actions is essential for goal-directed performance. In the event-related potential (ERP), errors are followed by fronto-centrally distributed negativities. These error(-related) negativity (Ne/ERN) amplitudes are often found to be attenuated in patients with Parkinson's disease (PD) compared to health...

journal_title：Scientific reports

authors： Seer C,Lange F,Loens S,Wegner F,Schrader C,Dressler D,Dengler R,Kopp B

更新日期：2017-01-24 00:00:00

abstract：:High Resolution Melt (HRM) is a versatile and rapid post-PCR DNA analysis technique primarily used to differentiate sequence variants among only a few short amplicons. We recently developed a one-vs-one support vector machine algorithm (OVO SVM) that enables the use of HRM for identifying numerous short amplicon seque...

journal_title：Scientific reports

authors： Fraley SI,Athamanolap P,Masek BJ,Hardick J,Carroll KC,Hsieh YH,Rothman RE,Gaydos CA,Wang TH,Yang S

更新日期：2016-01-18 00:00:00

abstract：:DNA N6-methyldeoxyadenosine (6 mA) modifications were first found more than 60 years ago but were thought to be only widespread in prokaryotes and unicellular eukaryotes. With the development of high-throughput sequencing technology, 6 mA modifications were found in different multicellular eukaryotes by using experime...

journal_title：Scientific reports

authors： Liu Z,Dong W,Jiang W,He Z

更新日期：2019-09-11 00:00:00

abstract：:Insects have evolved multiple mechanisms to adapt to variations in environmental temperatures, including postural control of solar input, variations in diurnal activity, external morphological structures and selecting/generating microhabitats. Foam produced by Mahanarva fimbriolata nymphs (also known as root spittlebu...

journal_title：Scientific reports

authors： Tonelli M,Gomes G,Silva WD,Magri NTC,Vieira DM,Aguiar CL,Bento JMS

更新日期：2018-03-16 00:00:00

abstract：:The fine-tuning of gene expression contributes to both basic science and applications. Here, we develop a novel gene expression technology termed CRITGI (CRISPR/Transposon gene integration). CRITGI uses CRISPR/Cas9 to integrate multiple copies of the plasmid pTy1 into Ty1 loci, budding yeast retrotransposons. The pTy1...

journal_title：Scientific reports

authors： Hanasaki M,Masumoto H

更新日期：2019-10-25 00:00:00

abstract：:Local communities are assembled from larger-scale species pools via dispersal, environmental filtering, biotic interactions, and local stochastic demographic processes. The relative importance, scaling and interplay of these assembly processes can be elucidated by comparing local communities to variously circumscribed...

journal_title：Scientific reports

authors： Feng G,Mi X,Eiserhardt WL,Jin G,Sang W,Lu Z,Wang X,Li X,Li B,Sun I,Ma K,Svenning JC

更新日期：2015-03-23 00:00:00

abstract：:Since their first appearance, organic-inorganic perovskite absorbers have been capturing the attention of the scientific community. While high efficiency devices highlight the importance of band level alignment, very little is known on the origin of the strong n-doping character observed in the perovskite. Here, by me...

journal_title：Scientific reports

authors： Caputo M,Cefarin N,Radivo A,Demitri N,Gigli L,Plaisier JR,Panighel M,Di Santo G,Moretti S,Giglia A,Polentarutti M,De Angelis F,Mosconi E,Umari P,Tormen M,Goldoni A

更新日期：2019-10-22 00:00:00

abstract：:In the following article, we present a simple, two-step method of creating spaced, hollow nanopillars, from the titania nanotube arrays via pulsed laser-treatment. Due to the high ordering of the structure, the prepared material exhibits photonic properties, which has been shown to increase the overall photoefficiency...

journal_title：Scientific reports

authors： Wawrzyniak J,Karczewski J,Kupracz P,Grochowska K,Coy E,Mazikowski A,Ryl J,Siuzdak K

更新日期：2020-11-19 00:00:00

abstract：:Pesticides are commonly used in food crop production systems to control crop pests and diseases and ensure maximum yield with high market value. However, the accumulation of these chemical inputs in crop fields increases risks to biodiversity and human health. In addition, people are increasingly seeking foods in whic...

journal_title：Scientific reports

authors： Ali MP,Bari MN,Haque SS,Kabir MMM,Afrin S,Nowrin F,Islam MS,Landis DA

更新日期：2019-07-15 00:00:00

abstract：:Memory function deficits induced by Alzheimer's disease (AD) are believed to be one of the causes of an increased risk of tripping in patients. Working memory contributes to accurate stepping over obstacles during locomotion, and AD-induced deficits of this memory function may lead to an increased risk of contact with...

journal_title：Scientific reports

authors： Setogawa S,Yamaura H,Arasaki T,Endo S,Yanagihara D

更新日期：2014-11-27 00:00:00

abstract：:A polarized macrophage response into inflammatory (M1) or regenerative/anti-inflammatory (M2) phenotypes is critical in host response to multiple intracellular bacterial infections. Ehrlichia is an obligate Gram-negative intracellular bacterium that causes human monocytic ehrlichiosis (HME): a febrile illness that may...

journal_title：Scientific reports

authors： Haloul M,Oliveira ERA,Kader M,Wells JZ,Tominello TR,El Andaloussi A,Yates CC,Ismail N

更新日期：2019-10-01 00:00:00

abstract：:Theoretical model required for the evolution of regular dislocation pattern should simultaneously take into account both static distribution and dynamic evolution of dislocation pattern. In principle, there exists a stable uniformly moving dislocation with both core and far field advancing at the same constant velocit...

journal_title：Scientific reports

authors： Li P,Zhang ZF

更新日期：2017-06-22 00:00:00