Abstract：
:Integrin activation is essential for creating functional transmembrane receptors capable of inducing downstream cellular effects such as cell migration, cell spreading, neurite outgrowth and axon regeneration. Integrins are bidirectional signalling molecules that mediate their effects by 'inside-out' and 'outside-in' signalling. This review will provide a detailed overview of integrin activation focusing on intracellular activation in neurons and discussing direct implications in the regulation of neurite outgrowth and axon regeneration.
journal_name
Cellsjournal_title
Cellsauthors
Cheah M,Andrews MRdoi
10.3390/cells7030020subject
Has Abstractpub_date
2018-03-10 00:00:00issue
3issn
2073-4409pii
cells7030020journal_volume
7pub_type
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