Application of 3D printing technology in RGPCL simulation fitting.

Abstract:

:The rigid gas permeable contact lens (RGPCL) is an ideal choice to improve the corrective vision of patients with a high degree of refractive error, keratoconus and corneal transplantation. However, RGPCL fitting is not an easy work for those patients with extremely irregular corneal surface. Technicians or doctors often need to try many times to determine the relatively satisfied lens customization parameters. This repeated try-on process not only increases discomfort of patients, but also will increase the risks of corneal epithelial shedding or corneal infection. In order to conduct RGP fitting in a faster and safer manner, a new method of simulating RGPCL fitting in 3D printing technology was assumed. The preliminary experimental results indicated that this method could effectively reduce the number of try-on and increase patient satisfaction, while decrease the risk of epithelial shedding or infection.

journal_name

Med Hypotheses

journal_title

Medical hypotheses

authors

Zhao F,Zhao G,Weijie F,Chen L

doi

10.1016/j.mehy.2018.02.028

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

74-76

eissn

0306-9877

issn

1532-2777

pii

S0306-9877(17)31310-5

journal_volume

113

pub_type

杂志文章
  • Breastfeeding: A standard or an intervention? Review of systematic reviews.

    abstract::Clinical trials designed to answer treatment-related questions typically compare an intervention group that receives a drug or other intervention to a control group that serves as a standard against which results of the intervention are evaluated. An observed divergence from this trend in research papers on breastfeed...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2020.109737

    authors: Dimnjakovic J,Poljicanin T,Svajda M

    更新日期:2020-08-01 00:00:00

  • Enhanced polymorphonuclear chemotaxis - a common feature of diseases responsive to colchicine.

    abstract::Increased chemotactic activity of peripheral polymorphonuclear (PMN) cells has been described in disease states of different etiology and may represent a common pathway in the generation of an inflammatory reaction. The suppressive effect of colchicine on PMN chemotaxis may explain its effect in apparently unrelated d...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(81)90017-7

    authors: Levy M,Ehrenfeld M,Gallily R,Eliakim M

    更新日期:1981-01-01 00:00:00

  • On the chemotherapeutic agents localization in tissue by means of snake venoms.

    abstract::The efficiency of anti-tumour drug strongly depends on its dose. Higher drug doses and exposure times usually result in better treatment. It is why the implementation of high-dose treatment is always attractive. However, most of the drug delivery techniques meet essential limitations. In isolated regional perfusion a ...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2017.05.025

    authors: Rukhlenko OS,Guria GT,Vorobiev AI

    更新日期:2017-07-01 00:00:00

  • Forecasting versus projection models in epidemiology: the case of the SARS epidemics.

    abstract::In this work we propose a simple mathematical model for the analysis of the impact of control measures against an emerging infection, namely, the severe acute respiratory syndrome (SARS). The model provides a testable hypothesis by considering a dynamical equation for the contact parameter, which drops exponentially w...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2004.09.029

    authors: Massad E,Burattini MN,Lopez LF,Coutinho FA

    更新日期:2005-01-01 00:00:00

  • Secretion of cytokines and modulation of function of immunologically competent cells.

    abstract::Cytokines and their effects are widely studied in immunology, but the cellular mechanisms responsible for producing these substances are not yet described or proven. Antigen presenting cells (APCs), macrophages and dendritic cells are suitable subjects for such a study. One of the many papers illustrating the interpla...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1054/mehy.1997.0720

    authors: Fedorko ME

    更新日期:1999-08-01 00:00:00

  • Have public hospitals outlived their usefulness? Is it possible to assess with health care parameters the impact of public hospitals on major American cities?

    abstract:BACKGROUND:Short-term acute care public county hospitals in the US were a mainstay of much "safety net" medical care in the early twentieth century. The private sector currently provides much of what was in the past public medical care. Does this transition affect health care indices? METHODS:The presence of public ho...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2019.109265

    authors: Shandera WX

    更新日期:2019-11-01 00:00:00

  • A novel immunotherapy to hepatocellular carcinoma: CD40-activated B lymphocytes transfected with AFPmRNA.

    abstract::Alpha-fetoprotein (AFP) is overexpressed in the majority of hepatocellular carcinomas (HCCs), and thus may offer attractive target for immunotherapy against this neoplasm. CD40 ligand (CD40L) is the major signal that induces B cells to efficiently present antigen to T cells, and CD40-activated B (CD40-B) lymphocyte ce...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2008.12.050

    authors: Wan Y,Ma X,Li X,Yi J

    更新日期:2009-11-01 00:00:00

  • Periodontal disease and targeted prevention using aMMP-8 point-of-care oral fluid analytics in the COVID-19 era.

    abstract::Periodontal disease is a chronic multifactorial infectious and inflammatory disease associated with several chronic systemic diseases, such as diabetes, cardiovascular diseases (CVD), chronic obstructive pulmonary disease, hypertension, Alzheimer's disease and so on. These same systemic diseases have been associated w...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2020.110276

    authors: Räisänen IT,Umeizudike KA,Pärnänen P,Heikkilä P,Tervahartiala T,Nwhator SO,Grigoriadis A,Sakellari D,Sorsa T

    更新日期:2020-11-01 00:00:00

  • Beef allergy and the Persian Gulf syndrome.

    abstract::It is suggested that the Persian Gulf Syndrome (PGS) is caused by beef allergy. In the first symptomless phase, as a result of an energetic US Army immunizing program, using sera with adjuvants to produce detectable antibody levels, the subjects not only developed immunity to the targeted substances, but also became s...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(95)90106-x

    authors: Hollander DH

    更新日期:1995-09-01 00:00:00

  • The Gamma Loop: a model of glomerular hemodynamics. Part II.

    abstract::The "Gamma Loop" Part I compared a model of rubber tubing to the architecture of the glomerulus with emphasis placed on the observed relationship between the position of the outflow resistance clamp and the perfusion of the loop (1, 2). Part II describes the pressures observed in the different parts of the loop, as we...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(89)90163-1

    authors: Gatzek WJ,Wells SC

    更新日期:1989-05-01 00:00:00

  • Alfred Nobel's unusual creativity: an analysis.

    abstract::Howard Gardner identified five different kinds of creative activity among eminent creators, namely, solving a well-defined problem, putting forth a general conceptual scheme, creating a product that embodies ideas, stylized innovation of an art form, and a 'high-stakes' performance in the socio-political arena. In thi...

    journal_title:Medical hypotheses

    pub_type: 传,历史文章,杂志文章

    doi:10.1054/mehy.1998.0777

    authors: Kantha SS

    更新日期:1999-10-01 00:00:00

  • The olive and central control of blood pressure.

    abstract::This evidence, then, would suggest that the olive becomes active when, with a change in the motor task, the motor performance is required to adjust to the new circumstance. From Smith's experiments on blood pressure, it is extrapolated that the olive becomes active when there is a change in the physiological state, an...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(78)90050-6

    authors: Kennedy PR

    更新日期:1978-11-01 00:00:00

  • Hypoxia inducible factors as mediators of reactive oxygen/nitrogen species homeostasis in physiological normoxia.

    abstract::Although once considered by biologists almost exclusively for their toxicity, reactive oxygen (ROS) and nitrogen (RNS) species produced within normal cells under baseline physiological conditions are now appreciated as redox regulators of a wide range of protein functions. Two families of enzymes, the NADPH oxidases (...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2019.109249

    authors: Stuart JA,Aibueku O,Bagshaw O,Moradi F

    更新日期:2019-08-01 00:00:00

  • Migraine: A disorder of metabolism?

    abstract::The treatment and prevention of migraine within the last decade has become largely pharmacological. While there is little doubt that the advent of drugs (e.g. triptans) has helped many migraine sufferers to lead a normal life, there is still little knowledge with respect to the factors responsible for precipitating a ...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2016.10.029

    authors: Kokavec A

    更新日期:2016-12-01 00:00:00

  • Immune response developing in tumorous organism as a result of immunotherapy. Chance of recovery?

    abstract::S-allylgutimine has immunostimulant and tumor cell inhibitory activities. This complex action may be a result of the stimulation of IL-2 production. The effectiveness of immunotherapy depends on the uncoupling of IL-2 downregulation. This principle can be widely used with those immunological diseases where IL-2 level ...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(93)90214-b

    authors: Vértesi C

    更新日期:1993-06-01 00:00:00

  • Permanent His bundle pacing to replace biventricular pacing for cardiac resynchronization therapy.

    abstract:INTRODUCTION:Cardiac resynchronization therapy (CRT) or biventricular pacing (BIVP) has become a common procedure for the treatment of ventricular dyssynchrony in patients with heart failure, particularly in those with bundle branch block patterns (QRS durations >150ms) on the electrocardiogram (ECG). However, a large ...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2017.09.026

    authors: Scherlag BJ,Papaila A

    更新日期:2017-11-01 00:00:00

  • Malignancy may contribute to rapid evolution.

    abstract::Characteristics of malignant tumors, including anaerobic metabolism and metastases to lung, liver, bone and brain, may permit the enhanced survival of edited parts of the genome during periods of rapid environmental change. Carcinogenesis may be partially analogous to fossilization. ...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(89)90150-3

    authors: Fischer K

    更新日期:1989-01-01 00:00:00

  • New theory of acoustic signal detection in the inner ear - An explanation of bifilar structure of the cochlea.

    abstract::In this work a new theory of acoustic signal detection in the inner ear and an experimental explanation of the causes of bifilar cochlear structure was presented. Our innovative approach describes sound detection in a completely different way from the one currently adopted. It requires analyzing the inner ear system i...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2020.109636

    authors: Dora J,Wojcieszak D,Kaczmarek D,Mazur M,Aksenczuk A

    更新日期:2020-02-18 00:00:00

  • Could exogenous melatonin prevent sudden infant death syndrome?

    abstract::Hypoplastic pineal glands and decreased melatonin levels are found in sudden infant death syndrome. Excess oxygen radical production and inadequate radical quenching is suggested to cause oxidative stress in the brain of sudden infant death syndrome victims. Loss of intraventricular cerebrospinal fluid melatonin could...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/s0306-9877(97)90091-8

    authors: Maurizi CP

    更新日期:1997-11-01 00:00:00

  • Construction of a bispecific antisense oligonucleotide containing multiple binding sites for the treatment of hormone insensitive prostate tumors.

    abstract::Antisense oligonucleotides (oligos) have demonstrated efficacy for the treatment of various cancers, infectious diseases and metabolic disorders. While most studies have utilized single oligos either administered alone, or more recently in combination therapy with other drugs, some investigators have administered more...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2004.12.032

    authors: Rubenstein M,Tsui P,Guinan P

    更新日期:2005-01-01 00:00:00

  • Salt addiction: a different kind of drug addiction.

    abstract::Under the headline "drug addiction" the medical world has exclusively been interested in psychoactive drugs. For diagnosis of substance dependence (addiction), DSM-IV-TR has determined seven criteria, and fulfilling at least tree of them signifies addiction. When studied salt intake according to these criteria it is s...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2006.04.041

    authors: Tekol Y

    更新日期:2006-01-01 00:00:00

  • Hypothesis: conjugate vaccines may predispose children to autism spectrum disorders.

    abstract::The first conjugate vaccine was approved for use in the US in 1988 to protect infants and young children against the capsular bacteria Haemophilus influenzae type b (Hib). Since its introduction in the US, this vaccine has been approved in most developed countries, including Denmark and Israel where the vaccine was ad...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2011.08.019

    authors: Richmand BJ

    更新日期:2011-12-01 00:00:00

  • Premature atherosclerosis in premenopausal women: Does cytokine balance play a role?

    abstract::Contributory risk factors to premature coronary artery disease (CAD) in premenopausal women are poorly understood and data on this subset of women is lacking. There is growing evidence that the process of inflammation is a part of the atherosclerotic process. Mechanistic insights from animal work suggest that the prof...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2017.09.010

    authors: Eastwood JA,Taylor DA,Johnson BD,Resende M,Sharaf BL,Ahmed B,Minissian M,Shufelt C,Merz NB

    更新日期:2017-11-01 00:00:00

  • Can methionine and zinc prevent the embryopathic effects of alcohol?

    abstract::Alcoholism is a major and world-wide health problem. A characteristic pattern of congenital defects, known as the fetal alcohol syndrome, has been detected in the offspring of mothers who are chronic alcoholics. The mechanism underlying the teratogenic effects of ethanol is not known. An important hypothesis is that e...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(91)90185-2

    authors: Seyoum GG,Persaud TV

    更新日期:1991-02-01 00:00:00

  • You are what you ate: the Biosetpoint hypothesis.

    abstract::The current epidemic of obesity has developed at a rate that cannot be attributed to genetic drift. Attempts to treat obesity using diet and activity have been largely disappointing. Genes are fixed at conception, but genetic expression is known to be influenced by nutriture during the stages of growth and development...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2006.02.019

    authors: Blonz ER

    更新日期:2006-01-01 00:00:00

  • Sphingomyelin: a natural modulator of membrane homeostasis and inflammation.

    abstract::Although membrane sphingomyelin (SPH) serves as the precursor for many signaling molecules, its presence in large amounts, and its specific localization in the outer monolayer of the plasma membrane suggest that it may have a cytoprotective function. We propose that SPH helps maintain the integrity of the plasma membr...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1054/mehy.2001.1336

    authors: Subbaiah PV,Sargis RM

    更新日期:2001-08-01 00:00:00

  • Margarines and coronary artery disease.

    abstract::In a previous paper we predicted that health effects of dietary fats in humans would require half a century or more to be understood, instead of the decade or so predicted during 1956 by an Editorial in The Lancet. It would seem that our prediction may have been optimistic since it has now been reported that trans uns...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(92)90194-h

    authors: Booyens J,van der Merwe CF

    更新日期:1992-04-01 00:00:00

  • Autologous bone marrow transplantation/mobilization: a potential regenerative medicine for systemic degenerative disorders and healthy living.

    abstract::Increased longevity is compromised for the quality of life due to prevalence of metabolic derangements and systemic degenerative disorders, as a result of lifestyle changes in modern days. In a craze to improve upon quality of life, use of pharmacological formulations aimed towards symptomatic treatment regimen is man...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2006.09.069

    authors: Banerjee M,Bhonde RR

    更新日期:2007-01-01 00:00:00

  • Are consumers satisfied with the use of prosthetic sports feet and the provision process? A mixed-methods study.

    abstract:BACKGROUND:Special feet connected to a prosthesis, prosthetic sports feet, enable athletes with a lower limb amputation to run. The selection of a prosthetic sports feet is usually based on body weight and preferred sports performance. The selection of a prosthetic sport feet is also based on clinicians who likely have...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2020.109869

    authors: Poonsiri J,van Putten SWE,Ausma AT,Geertzen JHB,Dijkstra PU,Dekker R

    更新日期:2020-10-01 00:00:00

  • Can testosterone replacement decrease the memory problem of old age?

    abstract::The world is rapidly ageing. It is against this backdrop that there are increasing incidences of dementia reported worldwide, with Alzheimer's disease (AD) being the most common form of dementia in the elderly. It is estimated that AD affects almost 4 million people in the US, and costs the US economy more than 65 mil...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/s0306-9877(03)00072-0

    authors: Lim D,Flicker L,Dharamarajan A,Martins RN

    更新日期:2003-06-01 00:00:00