Abstract:
:Aims High concentrations of air pollutants are associated with increased risk for myocardial infarction. The European Union has defined statutory limits for air pollutants based on upper absolute concentrations. We evaluated the association between rapid changes in air pollutants and the risk of myocardial infarction independently of absolute concentrations. Methods and results Using a hospital-based case-crossover study, effects of 24h changes of nitrogen oxides (NOX/2), particulate matter (PM10), and ozone on the risk of myocardial infarction was assessed in 693 patients. In the overall population, increases of NOX of more than 20 µg/m3 within 24 h were associated with an increase in the risk of myocardial infarction by up to 121% (odds ratio (OR) 2.21, 95% confidence interval (CI) 1.19-4.08). Comparably, rapid increases of NO2 of more than 8 µg/m3 tended to increase myocardial infarction risk by 73% (OR 1.73, 95% CI 0.91-3.28) while myocardial infarction risk decreased by 60% after a decrease of NO2 concentration of more than 8 µg/m3 (OR 0.4, 95% CI 0.21-0.77), suggesting a close-to-linear association. While results for ozone concentrations were ambiguous, rapid change in PM10 was not associated with myocardial infarction risk. Conclusion Dynamics and extent of increase in nitrogen oxide concentrations may be an independent risk factor for myocardial infarction. As there are currently no European Union statutory limits reflecting this dynamic variation of air pollutants on a daily basis, the results urgently call for confirming studies in different geographical regions to verify the observations.
journal_name
Eur J Prev Cardioljournal_title
European journal of preventive cardiologyauthors
Rasche M,Walther M,Schiffner R,Kroegel N,Rupprecht S,Schlattmann P,Schulze PC,Franzke P,Witte OW,Schwab M,Rakers Fdoi
10.1177/2047487318755804subject
Has Abstractpub_date
2018-11-01 00:00:00pages
1707-1716issue
16eissn
2047-4873issn
2047-4881journal_volume
25pub_type
杂志文章abstract::Background The relationships between dietary intake of soy foods and risk of cardiovascular disease are uncertain. The aims of this study were to evaluate and summarize the evidence on the association between consumption of soy and risk of cardiovascular disease (including stroke and coronary heart disease). Methods W...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1177/2047487316686441
更新日期:2017-05-01 00:00:00
abstract:AIMS:To investigate whether levels of thyroid-stimulating hormone (TSH) within the normal range are associated with an increased risk of new vascular events and mortality in patients with clinical manifest vascular diseases and whether this relation is influenced by adiposity. METHODS AND RESULTS:Prospective cohort st...
journal_title:European journal of preventive cardiology
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doi:10.1177/1741826711416045
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journal_title:European journal of preventive cardiology
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abstract::Despite the proven efficacy and cost-effectiveness of contemporary cardiovascular rehabilitation programmes, the referral to/uptake of and adherence to cardiovascular rehabilitation remains inadequate. In addition, heterogeneity persists amongst different cardiovascular rehabilitation centres in Europe, despite the av...
journal_title:European journal of preventive cardiology
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abstract::Background In view of the increasing heart failure epidemic and awareness of the adverse impact of environmental pollution on human health, we investigated the association of left ventricular structure and function with air pollutants in a general population. Methods In 671 randomly recruited Flemish (51.7% women; mea...
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更新日期:2017-09-01 00:00:00
abstract::Background The risk of cardiovascular disease is closely connected to adipose tissue inflammation. The links between cardiovascular risk predictors and pro and anti-inflammatory macrophages in human adipose tissue were analysed to gain an insight into the pathophysiology of cardiovascular disease. Design Subcutaneous ...
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abstract::Background Patient activity (PA) has been demonstrated to predict all-cause mortality. However, the association between PA and cardiac death is unclear. Aims The aims of this study were to determine whether PA can predict cardiac death and what is the cut-off of PA to discriminate cardiac death, as well as the mechani...
journal_title:European journal of preventive cardiology
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journal_title:European journal of preventive cardiology
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abstract:BACKGROUND:This study aimed to examine the mediating role of psychological distress in the relationship between the physical health component of health-related quality of life (HRQoL) of coronary heart disease patients and their socio-demographic and clinical characteristics. METHODS:This was a cross-sectional study c...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,多中心研究
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journal_title:European journal of preventive cardiology
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abstract::Background Exercise rehabilitation is highly recommended by current guidelines on prevention of cardiovascular disease, but its implementation is still poor. Many clinicians experience difficulties in prescribing exercise in the presence of different concomitant cardiovascular diseases and risk factors within the same...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,实务指引,评审
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abstract:AIMS:Exercise is recommended as prevention, management, and control of all stages of hypertension. There are still controversies about the optimal training dose, frequency, and intensity. We aimed to study the effect of aerobic interval training on blood pressure and myocardial function in hypertensive patients. METHO...
journal_title:European journal of preventive cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1177/1741826711400512
更新日期:2012-04-01 00:00:00
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journal_title:European journal of preventive cardiology
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doi:10.1177/2047487320903866
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journal_title:European journal of preventive cardiology
pub_type: 杂志文章,实务指引
doi:10.1177/2047487312460484
更新日期:2013-06-01 00:00:00
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journal_title:European journal of preventive cardiology
pub_type: 杂志文章,meta分析
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abstract::Aims To explore the predictive and explanatory factors on the incidence of cardiovascular disease and the impact of visit-to-visit variability (VVV) of risk factors on incident cardiovascular disease in people with type 2 diabetes with no history of prior cardiovascular disease. Methods We performed a historical cohor...
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pub_type: 临床试验,杂志文章
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journal_title:European journal of preventive cardiology
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doi:10.1177/1741826711406058
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