Association between consumption of soy and risk of cardiovascular disease: A meta-analysis of observational studies.

Abstract:

:Background The relationships between dietary intake of soy foods and risk of cardiovascular disease are uncertain. The aims of this study were to evaluate and summarize the evidence on the association between consumption of soy and risk of cardiovascular disease (including stroke and coronary heart disease). Methods We systematically searched the MEDLINE and EMBASE databases from their inception up to 22 February 2016. We included only observational studies, and used random-effects models to calculate summary relative risks (SRRs) and 95% confidence intervals (CIs). Results A total of 10 prospective cohort and seven case-control studies met the inclusion criteria. There were a total of 17,269 cardiovascular disease events, including 6265 stroke events, 10,806 coronary heart disease events, and 198 other cardiovascular disease events. A significant negative association was shown between soy intake and risk of cardiovascular disease (SRR = 0.84 95% CI: 0.75-0.94; pheterogeneity<0.001, I2 = 71.4%). Subgroup meta-analyses indicated that a statistically significant protective effect was primarily observed in case-control studies and in Asian populations. There was a borderline significant association between intake of tofu and the risk of cardiovascular disease (SRR = 0.80, 95% CI: 0.64-1.00). A significant negative association was shown for the association between soy intake and risk of stroke (SRR = 0.82, 95% CI: 0.68-0.99) and coronary heart disease (SRR = 0.83, 95% CI: 0.72-0.95). There were no associations between soy isoflavones consumption and risk of cardiovascular disease, stroke, and coronary heart disease. Conclusion Overall evidence indicated that consumption of soy was negatively associated with the risk of cardiovascular disease, stroke, and coronary heart disease risk.

journal_name

Eur J Prev Cardiol

authors

Yan Z,Zhang X,Li C,Jiao S,Dong W

doi

10.1177/2047487316686441

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

735-747

issue

7

eissn

2047-4873

issn

2047-4881

journal_volume

24

pub_type

杂志文章,meta分析,评审
  • Burden of premature atrial beats in middle-aged endurance athletes with and without lone atrial fibrillation versus sedentary controls.

    abstract:BACKGROUND:The burden of premature atrial beats (PABs) at 24-h electrocardiographic (ECG) monitoring correlates with the risk of atrial fibrillation. It is unknown whether prolonged and intense exercise increases the burden of PABs, thus contributing to the higher prevalence of atrial fibrillation observed in middle-ag...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319880042

    authors: Cipriani A,Vio R,Mastella G,Ciarmatori N,Del Monte A,Trovato D,Iliceto S,Schiavon M,Bertaglia E,Corrado D,Zorzi A

    更新日期:2020-09-01 00:00:00

  • Cardiovascular disease and risk factors in an indigenous minority population. The All-Ireland Traveller Health Study.

    abstract:BACKGROUND:The Traveller community are an indigenous minority group in Great Britain and Ireland who experience premature mortality. While minority populations worldwide are known to have high rates of risk factors for cardiovascular disease (CVD), Traveller CVD risk has not previously been defined. DESIGN:All-Ireland...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/1741826711428059

    authors: McGorrian C,Daly L,Fitzpatrick P,Moore RG,Turner J,Kelleher CC,All-Ireland Traveller Health Study Team.

    更新日期:2012-12-01 00:00:00

  • High ratios of kidney function to kidney size are related to mortality and kidney function decline in high-risk patients.

    abstract::Background The ratio of estimated glomerular filtration rate (eGFR) to kidney size reflects the kidney's capacity for filtration per kidney volume or kidney length. High ratios of eGFR to kidney size, which might indicate glomerular hyperfiltration, could be related to kidney function decline, cardiovascular disease a...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487317690950

    authors: van der Sande NG,Blankestijn PJ,Leiner T,van der Graaf Y,de Borst GJ,Cramer MJ,Visseren FL,SMART study group.

    更新日期:2017-06-01 00:00:00

  • Aerobic interval training reduces blood pressure and improves myocardial function in hypertensive patients.

    abstract:AIMS:Exercise is recommended as prevention, management, and control of all stages of hypertension. There are still controversies about the optimal training dose, frequency, and intensity. We aimed to study the effect of aerobic interval training on blood pressure and myocardial function in hypertensive patients. METHO...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/1741826711400512

    authors: Molmen-Hansen HE,Stolen T,Tjonna AE,Aamot IL,Ekeberg IS,Tyldum GA,Wisloff U,Ingul CB,Stoylen A

    更新日期:2012-04-01 00:00:00

  • Polypill for the prevention of cardiovascular disease (PolyIran): study design and rationale for a pragmatic cluster randomized controlled trial.

    abstract:BACKGROUND:The complexity of treatment regimens, costs and pill burden decrease the medication adherence and contribute to shortfall in cardiovascular preventive drug coverage. The polypill, a fixed dose combination pill of established drugs, is expected to increase adherence and reduce the costs whilst preventing majo...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/2047487314550803

    authors: Ostovaneh MR,Poustchi H,Hemming K,Marjani H,Pourshams A,Nateghi A,Majed M,Navabakhsh B,Khoshnia M,Jaafari E,Mohammadifard N,Malekzadeh F,Merat S,Sadeghi M,Naemi M,Etemadi A,Thomas GN,Sarrafzadegan N,Cheng KK,Marshal

    更新日期:2015-12-01 00:00:00

  • Interval training early after heart failure decompensation is safe and improves exercise tolerance and quality of life in selected patients.

    abstract::Aims To evaluate safety and efficacy of moderate intensity interval exercise training early after heart failure decompensation on exercise tolerance and health-related quality of life (HRQoL). Methods and results This is a prospective randomized controlled study. We screened 234 consecutive patients admitted with deco...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/2047487317724575

    authors: Doletsky A,Andreev D,Giverts I,Svet A,Brand A,Kuklina M,Sedov V,Dikur O,Syrkin A,Saner H

    更新日期:2018-01-01 00:00:00

  • Sesame oil consumption exerts a beneficial effect on endothelial function in hypertensive men.

    abstract:BACKGROUND:The aim of the study was to investigate the effects of sesame oil on endothelial function and to detect the underlying mechanisms, both in the postprandial state and after long-term consumption. DESIGN:We enrolled 30 hypertensive men in a two-phase study. In the first phase, 26 volunteers consumed 35 g of e...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487312437625

    authors: Karatzi K,Stamatelopoulos K,Lykka M,Mantzouratou P,Skalidi S,Zakopoulos N,Papamichael C,Sidossis LS

    更新日期:2013-04-01 00:00:00

  • Association of renal resistive index with aortic pulse wave velocity in hypertensive patients.

    abstract:BACKGROUND:Recent data suggest that renal haemodynamic parameters obtained by duplex Doppler sonography, especially the intrarenal resistive index (RI), may be associated with systemic vascular changes. However, conflicting data exist about the independent relationship between aortic stiffness and RI. The aim of this s...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487314524683

    authors: Geraci G,Mulè G,Geraci C,Mogavero M,D'Ignoto F,Morreale M,Foraci AC,Cottone S

    更新日期:2015-04-01 00:00:00

  • Strong inverse associations of Mediterranean diet, physical activity and their combination with cardiovascular disease: The Seguimiento Universidad de Navarra (SUN) cohort.

    abstract::Background Inverse associations of the Mediterranean diet (MedDiet) and physical activity with cardiovascular disease have been previously reported. We investigated the individual and combined contributions of both to this inverse association in a Mediterranean cohort. Design We used data from 19,536 participants from...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/2047487318783263

    authors: Alvarez-Alvarez I,de Rojas JP,Fernandez-Montero A,Zazpe I,Ruiz-Canela M,Hidalgo-Santamaría M,Bes-Rastrollo M,Martínez-González MÁ

    更新日期:2018-07-01 00:00:00

  • The benefits of exercise in cancer patients and the criteria for exercise prescription in cardio-oncology.

    abstract::Cancer and cardiovascular diseases are the leading causes of death in high-income countries. Cardiovascular complications can be found in cancer patients, being the result of so-called 'cardio-toxicity'. Therefore, it becomes essential to thoroughly investigate the origin of cardiac damage and the strategy to prevent ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319874900

    authors: D'Ascenzi F,Anselmi F,Fiorentini C,Mannucci R,Bonifazi M,Mondillo S

    更新日期:2019-10-06 00:00:00

  • Survey of physicians' practices in the control of cardiovascular risk factors: the EURIKA study.

    abstract:OBJECTIVES:To assess the practices of physicians in 12 European countries in the primary prevention of cardiovascular disease (CVD). METHODS:In 2009, 806 physicians from 12 European countries answered a questionnaire, delivered electronically or by post, regarding their assessment of patients with cardiovascular risk ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/1741826711407705

    authors: Dallongeville J,Banegas JR,Tubach F,Guallar E,Borghi C,De Backer G,Halcox JP,Massó-González EL,Perk J,Sazova O,Steg PG,Artalejo FR,EURIKA Investigators.

    更新日期:2012-06-01 00:00:00

  • Serum tissue-degrading proteinases and incident cardiovascular disease events.

    abstract:BACKGROUND:Extracellular matrix-degrading proteinases are upregulated in atherosclerotic lesions and can contribute to subsequent pathological events. In the present nested case-control study, we investigated the association of serum concentrations of matrix metalloproteinases MMP-7, MMP-8, and MMP-13, tissue inhibitor...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487312465524

    authors: Tuomainen AM,Kormi I,Havulinna AS,Tervahartiala T,Salomaa V,Sorsa T,Pussinen PJ

    更新日期:2014-07-01 00:00:00

  • Metabolic syndrome, diabetes mellitus, or both and cardiovascular risk in outpatients with or at risk for atherothrombosis.

    abstract:BACKGROUND:The incidence of metabolic syndrome (MetS), diabetes mellitus (DM), and their coexistence is increasing but whether MetS increases cardiovascular risk beyond component risk factors is controversial. DESIGN:We compared the risk of cardiovascular death, myocardial infarction, or stroke among patients with Met...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/2047487313500541

    authors: Udell JA,Steg PG,Scirica BM,Eagle KA,Ohman EM,Goto S,Alsheikh-Ali AA,Porath A,Corbalan R,Umez-Eronini AA,Hoffman EB,Wilson PW,Bhatt DL,Reduction of Atherothrombosis for Continued Health (REACH) Registry Investigators.

    更新日期:2014-12-01 00:00:00

  • Physical fitness is a modifiable predictor of early cardiovascular death: A 35-year follow-up study of 2014 healthy middle-aged men.

    abstract::Background Physical fitness has been shown to predict cardiovascular death during long-term follow-up. In the present study we aimed to investigate how physical fitness and other cardiovascular risk factors at middle-age influenced the risk of cardiovascular death during the early (0-11 years), intermediate (12-23 yea...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487318793459

    authors: Engeseth K,Prestgaard EE,Mariampillai JE,Grundvold I,Liestol K,Kjeldsen SE,Bodegard J,Erikssen JE,Gjesdal K,Skretteberg PT

    更新日期:2018-10-01 00:00:00

  • eHealth in cardiovascular medicine: A clinical update.

    abstract::Demographic changes, progress in medicine technology and regional problems in providing healthcare to low density populations are posing great challenges to our healthcare systems. Rapid progress in computer sciences and information technologies have a great impact on the way healthcare will be delivered in the near f...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,评审

    doi:10.1177/2047487316670256

    authors: Saner H,van der Velde E

    更新日期:2016-10-01 00:00:00

  • Status of dyslipidemia management and statin undertreatment in Korean cancer survivors: A Korean National Health and Nutrition Examination Survey study.

    abstract:AIMS:Due to improving cancer treatment results, non-cancer mortality is an important issue for cancer survivors. Cardiovascular diseases are the leading causes of death in Korea and globally. In addition to lowering the risk of cardiovascular disease, the use of statins has led to an overall reduction in cancer mortali...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487320905722

    authors: Shin S,Wook Shin D,Young Cho I,Jeong SM,Jung H

    更新日期:2020-02-23 00:00:00

  • Long term impact of one daily unit of physical exercise at school on cardiovascular risk factors in school children.

    abstract:BACKGROUND:Obesity and physical inactivity in children correlate with the presence of cardiovascular risk factors. The aim of this prospective, randomised, interventional study was to examine the long term impact of additional physical exercise lessons at school on fitness and cardiovascular risk factors. METHODS:We r...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/2047487316632966

    authors: Müller UM,Walther C,Adams V,Mende M,Adam J,Fikenzer K,Machalica KC,Erbs S,Linke A,Schuler G

    更新日期:2016-09-01 00:00:00

  • Impact of orlistat initiation on cardiovascular treatment use: a 6-year population-based cohort study.

    abstract:BACKGROUND:Trials of weight-loss drugs indicate some benefits on lipids, blood glucose, or blood pressure levels. Since obesity is associated with increased cardiovascular (CV) medication use and pharmaceutical costs, weight-loss drug use could beneficially impact CV medication use. OBJECTIVE:We examined the temporal ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/1741826711406058

    authors: Czernichow S,Knol MJ,Fezeu L,Grobbee DE

    更新日期:2012-06-01 00:00:00

  • Are poor health behaviours in anxious and depressed cardiac patients explained by sociodemographic factors?

    abstract:INTRODUCTION:While there is evidence of poor health behaviours in anxious and depressed cardiac patients, it is possible that sociodemographic factors explain these associations. Few previous studies have adequately controlled for confounders. The present study investigated health behaviours in anxious and depressed ca...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/2047487312449593

    authors: Murphy BM,Grande MR,Navaratnam HS,Higgins RO,Elliott PC,Turner A,Rogerson MC,Worcester MU,Goble AJ

    更新日期:2013-12-01 00:00:00

  • Persistence of uncontrolled cardiovascular risk factors in patients treated with percutaneous interventions for stable coronary artery disease not receiving cardiac rehabilitation.

    abstract:BACKGROUND:Cardiac rehabilitation programmes are strongly recommended for all forms of coronary artery disease to reduce recurrent events and mortality. Few patients seem to participate in these programmes after elective percutaneous coronary intervention (PCI). The aim of this study was to assess changes in lifestyle ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487312447751

    authors: Khattab AA,Knecht M,Meier B,Windecker S,Schmid JP,Wilhelm M,Saner H

    更新日期:2013-10-01 00:00:00

  • Exercise training improves neurovascular control and functional capacity in heart failure patients regardless of age.

    abstract:BACKGROUND:Exercise training is a non-pharmacological strategy for treatment of heart failure. Exercise training improves functional capacity and quality of life in patients. Moreover, exercise training reduces muscle sympathetic nerve activity (MSNA) and peripheral vasoconstriction. However, most of these studies have...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/1741826711414626

    authors: Antunes-Correa LM,Kanamura BY,Melo RC,Nobre TS,Ueno LM,Franco FG,Roveda F,Braga AM,Rondon MU,Brum PC,Barretto AC,Middlekauff HR,Negrao CE

    更新日期:2012-08-01 00:00:00

  • Sacubitril-valsartan versus enalapril for acute decompensated heart failure: a cost-effectiveness analysis.

    abstract:BACKGROUND:The Comparison of Sacubitril-Valsartan versus Enalapril on Effect on NT-proBNP in Patients Stabilised from an Acute Heart Failure Episode (PIONEER-HF) trial demonstrated significant reductions in N-terminal pro-B-type natriuretic peptide. Our study explored the cost-effectiveness of the use of sacubitril-val...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319878953

    authors: Perera K,Ademi Z,Liew D,Zomer E

    更新日期:2019-10-04 00:00:00

  • Exercise capacity and haemodynamic response among 12,327 individuals with cardio-metabolic risk factors undergoing treadmill exercise.

    abstract::Aims Haemodynamic parameters during and after exercise test seem to have a role in predicting cardiovascular events. We sought to evaluate the potential different responses in exercise capacity, heart rate and blood pressure levels in relation to major cardiovascular disease risk factors, among individuals undergoing ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487317726069

    authors: Chrysohoou C,Skoumas J,Georgiopoulos G,Liontou C,Vogiatzi G,Tsioufis K,Lerakis S,Soulis D,Pitsavos C,Tousoulis D

    更新日期:2017-10-01 00:00:00

  • The case for extended thromboprophylaxis in medically hospitalised patients - not yet made.

    abstract:BACKGROUND:The role of extended thromboprophylaxis is established for surgical patients, but not yet for hospitalised medical patients. DESIGN:This systematic review and meta-analysis sought to explore the role of extended thromboprophylaxis for medically ill hospitalised patients. METHODS:Medline, EMBASE and Cochran...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487319836572

    authors: Cao JY,Lee SY,Dunkley S,Adams M,Keech A

    更新日期:2019-03-16 00:00:00

  • Impacts of chronic kidney disease and diabetes on cardiovascular mortality in a general Japanese population: A 20-year follow-up of the NIPPON DATA90 study.

    abstract::Background Studies have shown significant associations of chronic kidney disease (CKD) and diabetes mellitus (DM) with cardiovascular disease (CVD) mortality. The impact on the general population is an important public health issue. However, the population attributable fraction (PAF) of CVD because of CKD and/or DM in...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487316679904

    authors: Hirata A,Okamura T,Sugiyama D,Kuwabara K,Kadota A,Fujiyoshi A,Miura K,Okuda N,Ohkubo T,Okayama A,Ueshima H,NIPPON DATA90 and 2010 Research Group.

    更新日期:2017-03-01 00:00:00

  • Effects of high-density lipoprotein targeting treatments on cardiovascular outcomes: A systematic review and meta-analysis.

    abstract:BACKGROUND:The effects of increasing high-density lipoprotein cholesterol on cardiovascular outcomes remain uncertain. DESIGN:We conducted a meta-analysis to investigate the effects of high-density lipoprotein cholesterol modifiers (niacin, fibrates and cholesteryl ester transfer protein inhibitors) on cardiovascular ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章,meta分析

    doi:10.1177/2047487318816495

    authors: Riaz H,Khan SU,Rahman H,Shah NP,Kaluski E,Lincoff AM,Nissen SE

    更新日期:2019-03-01 00:00:00

  • Transgenerational effects of parental cardiovascular disease and risk factors on offspring mortality: family-linkage data from the HUNT Study, Norway.

    abstract:BACKGROUND:Cardiovascular risk factors are known to be associated between parents and offspring. However, whether these associations are reflected in increased offspring mortality has not been extensively studied. DESIGN:This was a family study of 32,536 father-offspring and 39,614 mother-offspring pairs who participa...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487314562118

    authors: Vik KL,Romundstad P,Carslake D,Davey Smith G,Nilsen TI

    更新日期:2016-01-01 00:00:00

  • Risk factor levels, risk factor combinations, and residual coronary risk: population-based estimates for secondary prevention patients using statins.

    abstract:BACKGROUND:Population-based risk factor combinations and residual risks for coronary heart disease (CHD) patients on statins were assessed in order to bridge the gap between knowledge on relative effects from clinical trials and absolute risk from real-world practice. DESIGN:Population-based, retrospective 1-year cros...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/1741826710392668

    authors: Krobot KJ,Wagner A,Siebert U

    更新日期:2012-02-01 00:00:00

  • Prevalence of exertional oscillatory ventilation in continuous-flow left ventricular assist device recipients.

    abstract:BACKGROUND:Exercise oscillatory ventilation is an ominous outcome sign in heart failure due to reduced left ventricular ejection fraction; currently, the prevalence of exercise oscillatory ventilation is unknown in left ventricular assist device recipients. METHODS:We studied cardiopulmonary exercise testing in heart ...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487318801415

    authors: Pistono M,Gnemmi M,Imparato A,Komici K,Corrà U

    更新日期:2018-11-01 00:00:00

  • Underperformance of clinical risk scores in identifying vascular ultrasound-based high cardiovascular risk in systemic lupus erythematosus.

    abstract:AIMS:The aim of this study was to assess the performance of eight clinical risk prediction scores to identify individuals with systemic lupus erythematosus (SLE) at high cardiovascular disease (CVD) risk, as defined by the presence of atherosclerotic plaques. METHODS:CVD risk was estimated in 210 eligible SLE patients...

    journal_title:European journal of preventive cardiology

    pub_type: 杂志文章

    doi:10.1177/2047487320906650

    authors: Drosos GC,Konstantonis G,Sfikakis PP,Tektonidou MG

    更新日期:2020-03-02 00:00:00