In vivo characterization of brain metabolism by 1 H MRS, 13 C MRS and 18 FDG PET reveals significant glucose oxidation of invasively growing glioma cells.

abstract：:Conjugates (immunotoxins) comprising ricin A-chain and monoclonal antibody 96.5, which is specific for human melanoma-associated antigen p97, inhibited protein synthesis and colony formation of cultured human melanoma cells that expressed more than 80,000 molecules of p97 per cell. Cells expressing fewer than 5,000 mo...

journal_title：International journal of cancer

authors： Casellas P,Brown JP,Gros O,Gros P,Hellström I,Jansen FK,Poncelet P,Roncucci R,Vidal H,Hellström KE

更新日期：1982-10-15 00:00:00

abstract：:We studied plasmin receptors on 3 MCF-7 sublines: MCF7, MCF7R which was derived by transfection with v-Ha-ras oncogene, and MCF7MF which has been studied for the secretion of procathepsin D in the presence of estrogen. All 3 sublines bound plasmin (Pli) with a much higher affinity than plasminogen (Pg). The number of ...

journal_title：International journal of cancer

authors： Correc P,Fondanèche MC,Bracke M,Burtin P

更新日期：1990-10-15 00:00:00

abstract：:We investigated the therapeutic potential and molecular mechanism of adenovirus-mediated wt p53 gene therapy for drug-resistant human bladder cancers. KK47, a human bladder-cancer cell line, along with the drug-resistant sublines KK47/DDP10, KK47/DDP20 (cisplatin-resistant) and KK47/ADM (doxorubicin-resistant) were us...

journal_title：International journal of cancer

authors： Shirakawa T,Sasaki R,Gardner TA,Kao C,Zhang ZJ,Sugimura K,Matsuo M,Kamidono S,Gotoh A

更新日期：2001-10-15 00:00:00

abstract：:The association between subtypes of hepatitis C virus (HCV) and risk of hepatocellular carcinoma (HCC) remained inconclusive and evaluated in both case-control and cohort studies. In the case-control study, 397 HCC cases from medical centers were compared with 410 community-based non-HCC controls. All of them were ant...

journal_title：International journal of cancer

authors： Lee MH,Yang HI,Lu SN,Jen CL,You SL,Wang LY,L'Italien G,Chen CJ,Yuan Y,REVEAL-HCV Study Group.

更新日期：2014-09-01 00:00:00

abstract：:MaTu is a novel agent which may be of relevance in human oncogenesis, and has 2 components. One of them, the exogenous MX (coding for protein p58X), is transmissible to human fibroblasts, to HeLa and to HeLa x fibroblast (H/F) hybrids. The other component, MN, is a cellular gene. Its product, the protein p54/58N, is i...

journal_title：International journal of cancer

authors： Závada J,Závadová Z,Pastoreková S,Ciampor F,Pastorek J,Zelník V

更新日期：1993-05-08 00:00:00

abstract：:Hereditary non-polyposis colorectal cancer (HNPCC) is known to be associated with several extracolonic cancers, e.g., cancers of the endometrium, stomach, urinary tract, small bowel and ovary. An association between HNPCC and brain tumours has also been reported, although previous risk analysis did not reveal an exces...

journal_title：International journal of cancer

authors： Vasen HF,Sanders EA,Taal BG,Nagengast FM,Griffioen G,Menko FH,Kleibeuker JH,Houwing-Duistermaat JJ,Meera Khan P

更新日期：1996-02-08 00:00:00

abstract：:Previous studies have proved that a certain acidic isoform of ferritin is specifically synthesized by the placenta and breast-cancer tissue. In this context it has been further reported that the determination of this so-called placental isoferritin (PLF) on the surface of a subset of peripheral lymphocytes is highly s...

journal_title：International journal of cancer

authors： Rosen HR,Stierer M,Göttlicher J,Wolf H,Weber R,Vogl E,Eibl M

更新日期：1992-09-09 00:00:00

abstract：:Osteosacarcoma (OS) lung metastases are often resistant to chemotherapy. Most anticancer drugs are administered systemically. In many cases this is followed by dose-dependent toxicity, which may not allow the achievement of therapeutic levels in lungs to eradicate metastases. We determined the efficacy of gemcitabine ...

journal_title：International journal of cancer

authors： Koshkina NV,Kleinerman ES

更新日期：2005-09-01 00:00:00

abstract：:EBNA-positive lymphoblast cells were detected in 0.1 to 0.9% of the T-cell-depleted lymphocytes obtained from peripheral blood samples of five patients with infectious mononucleosis (IM). The same blood specimens from four of the five patients contained cells that formed EBNA-positive colonies in soft agar containing ...

journal_title：International journal of cancer

authors： Katsuki T,Hinuma Y,Saito T,Yamamoto J,Hirashima Y,Sudoh H,Deguchi M,Motokawa M

更新日期：1979-06-15 00:00:00

abstract：:Chromosome 17 is a frequent target during breast-cancer formation and progression. It has been shown to be affected by allele losses at multiple sites, as well as by DNA amplification. Our aim was to delineate a map of the genetic alterations on chromosome 17 in a given set of breast tumors. To this end we analyzed 15...

journal_title：International journal of cancer

authors： Kirchweger R,Zeillinger R,Schneeberger C,Speiser P,Louason G,Theillet C

更新日期：1994-01-15 00:00:00

abstract：:Deletions on chromosomes 1p and 19q are associated with favorable prognosis in patients with oligodendroglial tumors. The aim of our study was to identify additional genomic aberrations linked to patient survival. We performed a genome-wide screen for genomic imbalances by comparative genomic hybridization on tumors f...

journal_title：International journal of cancer

authors： Trost D,Ehrler M,Fimmers R,Felsberg J,Sabel MC,Kirsch L,Schramm J,Wiestler OD,Reifenberger G,Weber RG

更新日期：2007-06-01 00:00:00

abstract：:Recurrent deletions of chromosome fragments observed in neoplasms are thought to participate in tumor development through the inactivation of tumor-suppressor genes. In gliomas, the most frequent deletions involve chromosome arms 9p, 10q, 17p, 19q and 22q. We have analysed deletions of chromosome 22 in gliomas by stud...

journal_title：International journal of cancer

authors： Hoang-Xuan K,Merel P,Vega F,Hugot JP,Cornu P,Delattre JY,Poisson M,Thomas G,Delattre O

更新日期：1995-02-08 00:00:00

abstract：:We conducted a population-based case-control study of 1,447 incident rectal cancer cases and 3,106 population controls aged 20-76 years to assess the effect of recreational physical activity, energy intake and obesity on rectal cancer risk in 7 of 10 Canadian provinces in 1994-97. After adjustment for the effect of va...

journal_title：International journal of cancer

authors： Mao Y,Pan S,Wen SW,Johnson KC,Canadian Cancer Registries Epidemiology Research Group.

更新日期：2003-07-20 00:00:00

abstract：:Cancers of the stomach, pancreas, colon and rectum are increasingly regarded as being diet-influenced. Migrants to Australia from England, Scotland, Ireland, Poland, Yugoslavia, Greece, and Italy have come from countries with varied dietary backgrounds and gastrointestinal cancer risks. Age-standardized cancer death r...

journal_title：International journal of cancer

authors： McMichael AJ,McCall MG,Hartshorne JM,Woodings TL

更新日期：1980-04-15 00:00:00

abstract：:The object of our multicenter retrospective study was to compare the new histologic World Health Organization (WHO) classification and the classical histologic Bernatz classification in terms of interobserver agreement and prognostic importance. The influence of coexisting diseases was also analyzed using the Charlson...

journal_title：International journal of cancer

authors： Rieker RJ,Hoegel J,Morresi-Hauf A,Hofmann WJ,Blaeker H,Penzel R,Otto HF

更新日期：2002-04-20 00:00:00

abstract：:The kinetics of the immune response of hamsters transplanted with virus-free SV40 tumor cells (TSV5) to two SV40-coded non-structural proteins of 94,000 daltons (T antigen) and 17,000 daltons (t antigen) was studied in order to determine if the variation in the immune reactivity of serum from tumor-bearing animals tow...

journal_title：International journal of cancer

authors： Ransom JH,Thompson DL,Tevethia SS

更新日期：1982-02-15 00:00:00

abstract：:The impact of screening by visual inspection with acetic acid (VIA), cytology or HPV testing on cervical cancer incidence and mortality is investigated in a cluster randomized controlled trial in India. We report findings after the screening phase, when 52 clusters, with a total of 142,701 women aged 30-59 years in Os...

journal_title：International journal of cancer

authors： Sankaranarayanan R,Nene BM,Dinshaw KA,Mahe C,Jayant K,Shastri SS,Malvi SG,Chinoy R,Kelkar R,Budukh AM,Keskar V,Rajeshwarker R,Muwonge R,Kane S,Parkin DM,Chauhan MK,Desai S,Fontaniere B,Frappart L,Kothari A,Lucas E

更新日期：2005-09-10 00:00:00

abstract：:Cancer stem cells (CSCs) are initiating cells in colorectal cancer (CRC). Colorectal tumours undergo epithelial to mesenchymal transition (EMT)-like processes at the invasive front, enabling invasion and metastasis, and recent studies have linked this process to the acquisition of stem cell-like properties. It is of f...

journal_title：International journal of cancer

authors： Sarkar D,Shields B,Davies ML,Müller J,Wakeman JA

更新日期：2012-01-15 00:00:00

abstract：:Data from 1,916 cases of oral neoplasms occurring in the Sudan in a 16-year period, from January 1970 to December 1985, were retrieved and analysed. The study revealed a relatively high frequency of oral neoplasms in comparison with neighbouring countries. In this study, squamous-cell carcinoma was the most common ora...

journal_title：International journal of cancer

authors： Idris AM,Ahmed HM,Mukhtar BI,Gadir AF,el-Beshir EI

更新日期：1995-04-10 00:00:00

abstract：:Homeobox-containing genes are a network of genes encoding DNA-binding proteins highly conserved throughout evolution. They are involved in the control of normal development as well as in the regulation of gene expression in adult differentiating systems, including hematopoiesis. Aberrant expression of homeobox-contain...

journal_title：International journal of cancer

authors： Celetti A,Barba P,Cillo C,Rotoli B,Boncinelli E,Magli MC

更新日期：1993-01-21 00:00:00

abstract：:We have established a number of cell lines from Merkel cell carcinoma (MCC) of the skin. In many respects these cell lines resemble those established from small cell lung cancer (SCLC) and it is difficult to differentiate between metastatic MCC and SCLC on morphological or histochemical criteria. Both are thought to b...

journal_title：International journal of cancer

authors： Thomson JA,Leonard JH,McGregor K,Sturm RA,Parsons PG

更新日期：1994-07-15 00:00:00

abstract：:There is concern that hormone replacement therapy (HRT) increases the risk of breast cancer. We undertook a case-control study of this risk relationship within a cohort of 40- to 74-year-old women in Uppsala County, Sweden, who participated in mammography screening. Incident cases of breast cancer were ascertained dur...

journal_title：International journal of cancer

authors： Persson I,Thurfjell E,Bergstrom R,Holmberg L

更新日期：1997-09-04 00:00:00

abstract：:The incidence of testicular cancer was examined in the Nordic and Baltic countries, Poland and Germany by collaboration among 10 cancer registries. Population-based registers were used to analyze a total of 34,309 cases, diagnosed from the start of registration (varying from 1943 in Denmark to 1980 in Latvia and Lithu...

journal_title：International journal of cancer

authors： Adami HO,Bergström R,Möhner M,Zatoński W,Storm H,Ekbom A,Tretli S,Teppo L,Ziegler H,Rahu M

更新日期：1994-10-01 00:00:00

abstract：:The question of whether squamous cell carcinomas (SCCs) arising in different sites of lung are caused by different etiological factors is of obvious importance for prevention, early detection and effective treatment. We here subclassified a large series of resected SCCs (74 cases) into 3 tumor-sites, central (main to ...

journal_title：International journal of cancer

authors： Shimmyo T,Hashimoto T,Kobayashi Y,Miyagi Y,Ishikawa Y,Nakagawa K,Osada H,Tsuchiya E

更新日期：2006-08-01 00:00:00

abstract：:Abnormal survivin expression has been reported to be involved in many types of cancer. A single-nucleotide polymorphism (SNP), C-31G, located in the promoter region of survivin reportedly may alter the mRNA level, while the significance of the nonsynonymous SNP A9194G in exon 4 has not yet been clarified. Here, the as...

journal_title：International journal of cancer

authors： Kawata N,Tsuchiya N,Horikawa Y,Inoue T,Tsuruta H,Maita S,Satoh S,Mitobe Y,Narita S,Habuchi T

更新日期：2011-10-15 00:00:00

abstract：:Although preliminary evidence suggests that germline variation in genes involved in steroid hormone metabolism may alter breast cancer prognosis, this has not been systematically evaluated. We examined associations between germline polymorphisms in 6 genes involved in the steroid hormone metabolism and signaling pathw...

journal_title：International journal of cancer

authors： Udler MS,Azzato EM,Healey CS,Ahmed S,Pooley KA,Greenberg D,Shah M,Teschendorff AE,Caldas C,Dunning AM,Ostrander EA,Caporaso NE,Easton D,Pharoah PD

更新日期：2009-12-01 00:00:00

abstract：:A PCR assay using capillary electrophoresis was designed for the detection of c-erbB-2 gene amplification in alcohol-formalin-acetic acid (AFA)-fixed, paraffin-embedded biopsies from 81 consecutive breast tumors. c-erbB-2 expression was analyzed in the same samples using immuno-histochemistry (IHC). In the competitive...

journal_title：International journal of cancer

authors： de Cremoux P,Martin EC,Vincent-Salomon A,Dieras V,Barbaroux C,Liva S,Pouillart P,Sastre-Garau X,Magdelenat H

更新日期：1999-10-08 00:00:00

abstract：:Current evidence suggests poor identification and referral of Lynch syndrome patients. This study evaluated the strategies by which patients with endometrial cancer were referred to genetics services. Data from clinic-based patients with endometrial cancer enrolled through the Australian National Endometrial Cancer po...

journal_title：International journal of cancer

authors： Tan YY,McGaughran J,Ferguson K,Walsh MD,Buchanan DD,Young JP,Webb PM,Obermair A,Spurdle AB,ANECS Group.

更新日期：2013-06-15 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is a morbid cancer with poor outcomes. Statins possess anticancer properties such as immunomodulatory and anti-inflammatory effects. The objective of our study is to identify the association between statin use among untreated HNSCC patients and overall death, disease-speci...

journal_title：International journal of cancer

authors： Getz KR,Bellile E,Zarins KR,Rullman C,Chinn SB,Taylor JMG,Rozek LS,Wolf GT,Mondul AM

更新日期：2020-12-15 00:00:00

abstract：:Neuroendocrine gastrointestinal tumors take up, decarboxylate and store large amounts of monoamines. Radioactive-labeled monoamines like the norepinephrine analogue meta-iodobenzylguanidine (MIBG) have been used for the imaging of neuroendocrine tumors for many years. MIBG is selectively taken up via norepinephrine tr...

journal_title：International journal of cancer

authors： Höpfner M,Sutter AP,Beck NI,Barthel B,Maaser K,Jockers-Scherübl MC,Zeitz M,Scherübl H

更新日期：2002-09-20 00:00:00