Abstract：
AIMS:Many studies have suggested Cytomegalovirus infection might be implicated in steroid-refractory inflammatory bowel disease (IBD), in which situation management is extremely difficult. CMV infection being a potential cause of IBD have drawn great attention of clinicians, with insufficient evidence to reach conclusions. METHODS:We conduct this meta-analysis to explore the association of CMV infection and steroid-refractory IBD by collecting relevant articles. Literature collections were conducted by searching PubMed, EMBASE, and the cochrane library databases. Pooled risk ratios (RR) with corresponding 95% confidence intervals (CIs) were calculated to estimate the strength of the link between CMV infection and steroid resistance in IBD using Stata 12.0. RESULTS:Thirteen eligible studies with a total of 1119 patients conducted in eight countries were included. The steroid resistance rate in the CMV (+) groups was 62.8%, while that in the CMV (-) groups was 29.2%. The pooled RR of steroid resistance rate in CMV (+) groups compared to CMV (-) groups was 2.343 (95% CI 1.715-3.202, P = 0.0000). Due to marginal heterogeneity across studies (I2 = 77.6%), the random effects model was used. Subgroup analysis based on geographic differences did not alter the overall positive association between CMV infection and steroid resistance in IBD. There is no significant publication bias observed based on the funnel plot and Begg's test. CONCLUSIONS:This meta-analysis disclosed 2.34 fold increased risk of progressing into steroid-refractory IBD in CMV (+) group compared with the CMV (-) group, indicating that CMV infection might be a plausible cause of steroid-refractory IBD.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Liu CC,Ji S,Ding Y,Zhou L,Liu X,Li Wdoi
10.1007/s11845-018-1752-ysubject
Has Abstractpub_date
2018-11-01 00:00:00pages
935-942issue
4eissn
0021-1265issn
1863-4362pii
10.1007/s11845-018-1752-yjournal_volume
187pub_type
杂志文章,meta分析abstract：BACKGROUND:Platelets are involved in atherosclerosis. Mean platelet volume (MPV) could be a marker of platelet activation. We aim to determine whether MPV levels were correlated with the presence of atherosclerotic disease in carotid arteries of patients with stroke. METHODS:We recruited 215 patients with atherothromb...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-011-0755-8
更新日期：2012-06-01 00:00:00
abstract：AIM:The aim of this study was to investigate the microbiology of secondary bacterial peritonitis due to appendicitis and the appropriateness of current antimicrobial practice in one institution. METHODS:A 14-year retrospective single-centre study of 69 consecutive paediatric patients (age 1-14 years) with appendicitis...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1055-2
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Increasing prevalence of overweight and obese children in developed countries poses a substantial threat to long-term health. One well-described factor is the amount of time spent watching television, with exposure to food advertising a known influence on food preferences and consumption patterns. AIMS:Foll...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-014-1088-1
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Dysphagia affects up to 30% of hospitalized patients, and it is associated with numerous complications. AIMS:Assess the impact of a 24/7 dysphagia screening protocol in an Internal Medicine Unit regarding respiratory complications (such as aspiration pneumonia) as the primary outcome. Length of stay and dis...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02371-8
更新日期：2020-09-22 00:00:00
abstract：:Serum antibodies to Epstein-Barr virus (EBV) were measured in members of twenty-nine families in which two or more first degree relatives had rheumatoid arthritis (RA). These patients were assessed clinically for activity of disease and their treatment recorded. A higher proportion of seropositive individuals was foun...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943612
更新日期：1989-08-01 00:00:00
abstract：:All the biopsies of pulmonary mass lesions obtained by percutaneous needle aspiration over a seven year period were reviewed. Emphasis is laid upon the differences in cell typing of malignant tumours when two types of preparation of the same tissue, cytological smears and tissue sections are examined. Some problems in...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942112
更新日期：1989-04-01 00:00:00
abstract：BACKGROUND:Acute scrotal pain is a common urological emergency. Urgent exploration is the standard means of management, as no investigation can confidently exclude torsion of testis from the differential diagnoses. In our department, all patients up to the age of 40 years, presenting with acute scrotal pain undergo eme...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03173885
更新日期：2001-07-01 00:00:00
abstract：INTRODUCTION:Heparin-induced thrombocytopenia syndrome (HITS) is an infrequent complication of heparin anticoagulation. CASE REPORT:We present the case of a 44-year-old male who was admitted with acute ischaemia of his right lower limb. He was initially treated with unfractionated heparin and thrombolysis, but subsequ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0531-1
更新日期：2012-09-01 00:00:00
abstract：:Two term infants suffering severe asphyxial events were found to have diffusely high attenuation of the cortical gyri on CT scanning within 12 days. The findings are consistent with haemorrhagic necrosis or microcalcification. This feature has rarely been described in the literature. The evolution of the CT appearance...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937934
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND:The weight of the delivered placenta gives a useful representation of placental function in utero. In the absence of Irish data, many pathologists rely on data from other populations, many of which are now 15 to 30 years old. The development of a population-specific nomogram would aid in the examination of p...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02102-8
更新日期：2020-05-01 00:00:00
abstract：INTRODUCTION:The "National Integrated Medical Imaging System" or NIMIS went live in 2011 and allows the movement of patient radiology imaging throughout the Irish health system. At the time of its launch, NIMIS was not only going to allow the filmless passage of patient radiology imaging but it was also envisaged that ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-018-1900-4
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:Injecting drug use is associated with increased morbidity and mortality. This is the first longitudinal study of a community-based population of injecting drug users (IDUs) in the Republic of Ireland. AIM:To establish the natural history of IDUs in a deprived Dublin community. METHODS:Eighty-two IDUs (hero...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-012-0814-9
更新日期：2012-12-01 00:00:00
abstract：:The establishment of the Dublin Hospitals Initiative and the Efficiency Review Group as first steps in an "action" plan was based on the report in 1989 of the Commission of Health Funding which suggested that "the solution to the problem facing the Irish health services...(lies) primarily...in the way that services ar...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02973395
更新日期：1991-08-01 00:00:00
abstract：OBJECTIVES:The European and American colonoscopy guidelines recommend mandatory photodocumentation of caecal intubation to allow retrospective analysis and improve outcomes. We aim to demonstrate whether photodocumentation of caecal intubation improves colonoscopy outcomes. METHODS:We extracted images and procedural d...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02469-z
更新日期：2021-01-20 00:00:00
abstract：BACKGROUND:Cancellation of operations increases theatre costs and decreases efficiency. We examined the causes of theatre cancellations in general surgery. METHODS:The Beaumont hospital database (ORSUS system) and theatre records were examined retrospectively between April 1997 and March 2002. The number and causes of...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167925
更新日期：2004-07-01 00:00:00
abstract：:The management of patients with suspected post laparotomy intra-abdominal sepsis poses a major therapeutic challenge to clinicians. The mortality is high and the optimal interventional modality remains ill-defined. We define the incidence, diagnostic methodology, pre- and postoperative findings and outcome of patients...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02944195
更新日期：1997-04-01 00:00:00
abstract：BACKGROUND:Attitudes have been shown to be important determinants of the quality and efficacy of medical care. There is little research on the education about, and assessment of, attitudes in undergraduate medical education. AIM:To describe the design and delivery of an attitude awareness workshop, and the associated ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170282
更新日期：2002-10-01 00:00:00
abstract：AIMS:To evaluate the potential role of key DNA repair proteins in the sensitivity of normal human fibroblasts to ionising radiations. METHODS:Radiosensitivity of six human fibroblast strains established from skin biopsies of women who had undergone conservative breast surgery and received a curative breast conserving ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0554-7
更新日期：2011-09-01 00:00:00
abstract：:A new investigative modality, cervicography, has been advocated for cervical screening. In the first 51 patients referred for colposcopy because of an abnormal cervicogram, none had invasive cancer and 75% had preinvasive cancer. The cervicogram appears superior to cytology but inferior to colposcopy in the detection ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02937249
更新日期：1990-02-01 00:00:00
abstract：INTRODUCTION:Childhood obesity is associated with increased risk of adult obesity, cardiovascular disease, diabetes and cancer. Appropriate techniques for assessment of childhood adiposity are required to identify children at risk. The aim of this review was to examine core clinical measurements and more technical tool...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-014-1124-1
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Hemoglobin (HB) and red cell distribution width (RDW) are known to be prognostic in many cancer types. The HB-RDW ratio (HRR) is a new biomarker that has been shown to be predictive in some cancer types. However, the prognostic significance of HRR in patients with gastric cancer (GC) is unknown. AIMS:In thi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02153-x
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:A review of theatre activity in all Health Service Executive (HSE) hospitals in Cork and Kerry in 2008 required a manual extraction of theatre activity data from largely paper-based log books. A key data management recommendation suggested that "a standardised computerised theatre log book system be develope...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1030-y
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:There is no agreeing if rescue therapy can avoid short-term colectomy in patients treated for severe steroid-refractory ulcerative colitis. AIMS:The aim of our study was to identify predictors of response to infliximab and cyclosporine A. METHODS:In this cross-sectional study, 49 patients with severe ulcer...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1666-0
更新日期：2018-05-01 00:00:00
abstract：:More than 300 risk factors for coronary artery disease (CAD) have been described. There are important geographical and racial differences in both the prevalence of CAD and of potential risk factors. The purpose of this study was to determine the relationship between both the presence and extent of angiographically def...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943801
更新日期：1996-04-01 00:00:00
abstract：:A case of cervical pregnancy resulting in intra abdominal rupture in the first trimester is reported. The clinical features of this rare cause of uterine rupture are outlined. Pathological examination of the uterus showed placenta percreta. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942011
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Pain is one of the primary motivations for patients to seek medical advice. Pain location is one element in the process of formulating a diagnosis. AIMS:The purpose of the study is to determine if there is a correlation between the location of pain and the location of pathology in the knees of patients with...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-0965-3
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Assessment of non-cardiac chest pain places a considerable burden on healthcare resources. The current practice of serial electrocardiographs (ECGs), serum creatinine phosphokinase and by pre-discharge exercise electrocardiography gives an average in-hospital stay of 3.7 days. AIMS:This study assess the use...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03167689
更新日期：2000-07-01 00:00:00
abstract：:A study is presented of the skin manifestations of 30 patients, 25 females and 5 males, with systemic lupus erythematosus (S.L.E.) admitted to this hospital over a two year period. Their ages ranged from 20 years to 75 years. The diagnosis of S.L.E. was made according to the criteria laid down for the diagnosis of S.L...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02938956
更新日期：1976-12-01 00:00:00
abstract：BACKGROUND:Left cardiac sympathetic denervation (LCSD) is a surgical procedure that has been shown to have an antiarrhythmic and antifibrillatory effect. Evidence indicating its antiarrhythmic effect has been available for over 100 years. It involves the removal of the lower half of the stellate ganglion and T2-T4 of t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1577-0
更新日期：2017-08-01 00:00:00
abstract：:Ninety-nine inguinal herniorrhaphies were performed under local anaesthetic blockade between 1980 and 1988. This represents 32% of this surgical teams herniorrhaphy operations. A follow-up interview was possible in 82 patients. Satisfaction was expressed by 77 patient (94%) although six of the interviewed patients (7....
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942128
更新日期：1994-06-01 00:00:00
