当前位置： SCI文献检索 > Scientific Reports期刊下所有文献 > Transcriptome Analysis in Spleen Reveals Differential Regulation of Response to Newcastle Disease Virus in Two Chicken Lines.

Transcriptome Analysis in Spleen Reveals Differential Regulation of Response to Newcastle Disease Virus in Two Chicken Lines.

Abstract：

:Enhancing genetic resistance of chickens to Newcastle Disease Virus (NDV) provides a promising way to improve poultry health, and to alleviate poverty and food insecurity in developing countries. In this study, two inbred chicken lines with different responses to NDV, Fayoumi and Leghorn, were challenged with LaSota NDV strain at 21 days of age. Through transcriptome analysis, gene expression in spleen at 2 and 6 days post-inoculation was compared between NDV-infected and control groups, as well as between chicken lines. At a false discovery rate <0.05, Fayoumi chickens, which are relatively more resistant to NDV, showed fewer differentially expressed genes (DEGs) than Leghorn chickens. Several interferon-stimulated genes were identified as important DEGs regulating immune response to NDV in chicken. Pathways predicted by IPA analysis, such as "EIF-signaling", "actin cytoskeleton organization nitric oxide production" and "coagulation system" may contribute to resistance to NDV in Fayoumi chickens. The identified DEGs and predicted pathways may contribute to differential responses to NDV between the two chicken lines and provide potential targets for breeding chickens that are more resistant to NDV.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Zhang J,Kaiser MG,Deist MS,Gallardo RA,Bunn DA,Kelly TR,Dekkers JCM,Zhou H,Lamont SJ

doi

10.1038/s41598-018-19754-8

subject

Has Abstract

pub_date

2018-01-19 00:00:00

pages

1278

issue

1

issn

2045-2322

pii

10.1038/s41598-018-19754-8

journal_volume

8

pub_type

杂志文章

相关文献

Scientific Reports文献大全
  • Author Correction: Moderate acute alcohol intoxication increases visual motion repulsion.

    abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

    journal_title：Scientific reports

    pub_type： 已发布勘误

    doi：10.1038/s41598-019-44354-5

    authors： Wang Z,Wang H,Tzvetanov T,Zhou Y

    更新日期：2019-05-23 00:00:00

  • Integration of neurogenesis and angiogenesis models for constructing a neurovascular tissue.

    abstract：:Neurovascular unit (NVU) is a basic unit in the brain, including neurons, glial cells, blood vessels and extracellular matrix. This concept implies the importance of a three-dimensional (3D) culture model including these cell types for investigating brain functions. However, little is known about the construction of a...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-17411-0

    authors： Uwamori H,Higuchi T,Arai K,Sudo R

    更新日期：2017-12-11 00:00:00

  • Successful selection of mouse sperm with high viability and fertility using microfluidics chip cell sorter.

    abstract：:Cell sorting via flow cytometry is a powerful tool to select subpopulations of cells in many biological fields. Selection of fertilisation-prone sperm is a critical step to ensure a stable and high fertilisation rate in in vitro fertilisation (IVF). However, a combination of conventional cell sorting and IVF system ha...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-65931-z

    authors： Nakao S,Takeo T,Watanabe H,Kondoh G,Nakagata N

    更新日期：2020-06-01 00:00:00

  • Human oral isolate Lactobacillus fermentum AGR1487 induces a pro-inflammatory response in germ-free rat colons.

    abstract：:Lactobacilli are thought to be beneficial for human health, with lactobacilli-associated infections being confined to immune-compromised individuals. However, Lactobacillus fermentum AGR1487 negatively affects barrier integrity in vitro so we hypothesized that it caused a pro-inflammatory response in the host. We comp...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep20318

    authors： Anderson RC,Ulluwishewa D,Young W,Ryan LJ,Henderson G,Meijerink M,Maier E,Wells JM,Roy NC

    更新日期：2016-02-04 00:00:00

  • The diagnostic value of human epididymis protein 4 for endometrial cancer is moderate.

    abstract：:Human epididymis protein 4 (HE4) has been used as a biomarker of endometrial cancer (EC) in clinical practice. However, there remains a lack of systemic research on the critical values of HE4 for diagnosing different clinical stages and pathological types of EC. This study investigated the accuracy of human epididymis...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-79960-1

    authors： Liu J,Han L,Jiao Z

    更新日期：2021-01-12 00:00:00

  • Photosynthetic protein classification using genome neighborhood-based machine learning feature.

    abstract：:Identification of novel photosynthetic proteins is important for understanding and improving photosynthetic efficiency. Synergistically, genome neighborhood can provide additional useful information to identify photosynthetic proteins. We, therefore, expected that applying a computational approach, particularly machin...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-64053-w

    authors： Sangphukieo A,Laomettachit T,Ruengjitchatchawalya M

    更新日期：2020-04-28 00:00:00

  • Analysis of the genetic association between IL27 variants and coronary artery disease in a Chinese Han population.

    abstract：:Interleukin-27 (IL-27) is an important cytokine in inflammatory diseases, including coronary artery disease (CAD). To explore the precise role of IL-27 in CAD, we investigated the genetic association between IL27 and CAD in the GeneID Chinese Han population. A two-stage case control association analysis was performed ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep25782

    authors： Fan Q,Nie S,Li S,Liao Y,Zhang H,Zha L,Wang F,Tang T,Xia N,Xu C,Wang P,Xie T,Xie J,Lu Q,Li Q,Qian J,Li B,Wu G,Wu Y,Yang Y,Wang QK,Tu X,Cheng X

    更新日期：2016-05-12 00:00:00

  • Tricolor R/G/B Laser Diode Based Eye-Safe White Lighting Communication Beyond 8 Gbit/s.

    abstract：:White light generation by mixing red, green, and blue laser diodes (RGB LDs) was demonstrated with Commission International de l'Eclairage coordinates of (0.2928, 0.2981), a correlated color temperature of 8382 K, and a color rendering index of 54.4 to provide a maximal illuminance of 7540 lux. All the white lights ge...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-00052-8

    authors： Wu TC,Chi YC,Wang HY,Tsai CT,Huang YF,Lin GR

    更新日期：2017-01-31 00:00:00

  • Comparison of Accuracy of Arrival-Time-Insensitive and Arrival-Time-Sensitive CTP Algorithms for Prediction of Infarct Tissue Volumes.

    abstract：:The purpose of this study was to compare the performance of arrival-time-insensitive (ATI) and arrival-time-sensitive (ATS) computed tomography perfusion (CTP) algorithms in Philips IntelliSpace Portal (v9, ISP) and to investigate optimal thresholds for ATI regarding the prediction of final infarct volume (FIV). Retro...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-66041-6

    authors： Pennig L,Thiele F,Goertz L,Laukamp KR,Perkuhn M,Kabbasch C,Schlamann M,Fink GR,Borggrefe J

    更新日期：2020-06-09 00:00:00

  • A novel design to screen chlorogenic acid-producing microbial strains from the environment.

    abstract：:The present study aimed to develop a plate-screening method, based on the specific color development of complexes formed between chlorogenic acid, a valuable plant-derived compound, and aluminum (III), to detect chlorogenic acid-producing microbial strains. Modified media with 0.75 mM aluminum chloride were developed ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-32968-0

    authors： Wang X,Qin L,Zhou J,Li Y,Fan X

    更新日期：2018-10-03 00:00:00

  • Administration of Lactobacillus salivarius LI01 or Pediococcus pentosaceus LI05 prevents CCl4-induced liver cirrhosis by protecting the intestinal barrier in rats.

    abstract：:Alterations in the gut microbiome have been reported in liver cirrhosis, and probiotic interventions are considered a potential treatment strategy. This study aimed to evaluate the effects and mechanisms of Lactobacillus salivarius LI01, Pediococcus pentosaceus LI05, Lactobacillus rhamnosus GG, Clostridium butyricum M...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-07091-1

    authors： Shi D,Lv L,Fang D,Wu W,Hu C,Xu L,Chen Y,Guo J,Hu X,Li A,Guo F,Ye J,Li Y,Andayani D,Li L

    更新日期：2017-07-31 00:00:00

  • D5 dopamine receptors control glutamatergic AMPA transmission between the motor cortex and subthalamic nucleus.

    abstract：:Corticofugal fibers target the subthalamic nucleus (STN), a component nucleus of the basal ganglia, in addition to the striatum, their main input. The cortico-subthalamic, or hyperdirect, pathway, is thought to supplement the cortico-striatal pathways in order to interrupt/change planned actions. To explore the previo...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-27195-6

    authors： Froux L,Le Bon-Jego M,Miguelez C,Normand E,Morin S,Fioramonti S,Barresi M,Frick A,Baufreton J,Taupignon A

    更新日期：2018-06-11 00:00:00

  • Biosynthesis of CuO nanoparticles using aqueous extract of herbal tea (Stachys Lavandulifolia) flowers and evaluation of its catalytic activity.

    abstract：:Plant derived biogenic synthesis of nanoparticles (NP) has been the recent trend in material science as featured sustainable catalysts. A great deal of the current nanocatalytic research has been oriented on the bio-inspired green catalysts based on their wide applicability. In this context, CuO NPs are synthesized fo...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-021-81320-6

    authors： Veisi H,Karmakar B,Tamoradi T,Hemmati S,Hekmati M,Hamelian M

    更新日期：2021-01-21 00:00:00

  • The time course of auditory recognition measured with rapid sequences of short natural sounds.

    abstract：:Human listeners are able to recognize accurately an impressive range of complex sounds, such as musical instruments or voices. The underlying mechanisms are still poorly understood. Here, we aimed to characterize the processing time needed to recognize a natural sound. To do so, by analogy with the "rapid visual seque...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-43126-5

    authors： Isnard V,Chastres V,Viaud-Delmon I,Suied C

    更新日期：2019-05-29 00:00:00

  • Fully fledged enantiornithine hatchling revealed by Laser-Stimulated Fluorescence supports precocial nesting behavior.

    abstract：:Laser-Stimulated Fluorescence (LSF) is used to identify fully fledged feathering in the hatchling enantiornithine bird specimen MPCM-LH-26189, supporting precocial nesting behavior in this extinct group. The LSF results include the detection of a long pennaceous wing feather as well as cover feathers around the body. ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-41423-7

    authors： Kaye TG,Pittman M,Marugán-Lobón J,Martín-Abad H,Sanz JL,Buscalioni AD

    更新日期：2019-03-21 00:00:00

  • Chemical transfer of dissolved organic matter from surface seawater to sea spray water-soluble organic aerosol in the marine atmosphere.

    abstract：:It is critical to understand how variations in chemical composition in surface seawater (SSW) affect the chemistry of marine atmospheric aerosols. We investigated the sea-to-air transfer of dissolved organic carbon (DOC) via cruise measurements of both ambient aerosols and SSW in the Oyashio and its coastal regions, t...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-32864-7

    authors： Miyazaki Y,Yamashita Y,Kawana K,Tachibana E,Kagami S,Mochida M,Suzuki K,Nishioka J

    更新日期：2018-10-05 00:00:00

  • Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing.

    abstract：:Capable of mediating efficient transfection and protein production without eliciting innate immune responses, chemically modified mRNA holds great potential to produce paracrine factors at a physiologically beneficial level, in a spatiotemporally controlled manner, and with low toxicity. Although highly promising in c...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-35570-6

    authors： Sun N,Ning B,Hansson KM,Bruce AC,Seaman SA,Zhang C,Rikard M,DeRosa CA,Fraser CL,Wågberg M,Fritsche-Danielson R,Wikström J,Chien KR,Lundahl A,Hölttä M,Carlsson LG,Peirce SM,Hu S

    更新日期：2018-11-30 00:00:00

  • Chronic dysfunction of Stromal interaction molecule by pulsed RNAi induction in fat tissue impairs organismal energy homeostasis in Drosophila.

    abstract：:Obesity is a progressive, chronic disease, which can be caused by long-term miscommunication between organs. It remains challenging to understand how chronic dysfunction in a particular tissue remotely impairs other organs to eventually imbalance organismal energy homeostasis. Here we introduce RNAi Pulse Induction (R...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-43327-y

    authors： Xu Y,Borcherding AF,Heier C,Tian G,Roeder T,Kühnlein RP

    更新日期：2019-05-06 00:00:00

  • Delayed discharge is associated with higher complement C3 levels and a longer nucleic acid-negative conversion time in patients with COVID-19.

    abstract：:To determine factors associated with delayed discharge of hospitalized patients with coronavirus disease (COVID-19). This retrospective cohort study included 47 patients with COVID-19 admitted to three hospitals in Quanzhou City, Fujian Province, China, between January 21, 2020 and March 6, 2020. Univariate and multiv...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-021-81010-3

    authors： Lin P,Chen W,Huang H,Lin Y,Cai M,Lin D,Cai H,Su Z,Zhuang X,Yu X

    更新日期：2021-01-13 00:00:00

  • Radio-frequency current drive for thermonuclear fusion reactors.

    abstract：:Principal research on energy from thermonuclear fusion uses Deuterium-Tritium plasmas magnetically trapped in toroidal devices. As major scientific problem for an economic (i.e., really feasible) reactor, we must understand how to lead strongly heated plasmas to sustain a high fusion gain while large fraction of curre...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-27996-9

    authors： Cardinali A,Castaldo C,Cesario R,Amicucci L,Galli A,Napoli F,Panaccione L,Riccardi C,Santini F,Schettini G,Tuccillo AA

    更新日期：2018-07-09 00:00:00

  • Nanoscale graphene Hall sensors for high-resolution ambient magnetic imaging.

    abstract：:A major challenge to routine non-invasive, nanoscale magnetic imaging is the development of Hall sensors that are stable under ambient conditions and retain low minimum detectable fields down to nanoscale dimensions. To address these issues we have fabricated and characterised chemical vapour deposition (CVD) graphene...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-50823-8

    authors： Collomb D,Li P,Bending SJ

    更新日期：2019-10-08 00:00:00

  • Potential of Pantoea dispersa as an effective biocontrol agent for black rot in sweet potato.

    abstract：:Biocontrol offers a promising alternative to synthetic fungicides for the control of a variety of pre- and post-harvest diseases of crops. Black rot, which is caused by the pathogenic fungus Ceratocytis fimbriata, is the most destructive post-harvest disease of sweet potato, but little is currently known about potenti...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-52804-3

    authors： Jiang L,Jeong JC,Lee JS,Park JM,Yang JW,Lee MH,Choi SH,Kim CY,Kim DH,Kim SW,Lee J

    更新日期：2019-11-08 00:00:00

  • Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing.

    abstract：:HIV-1 Tat protein is released from HIV-1-infected cells and can enter non-permissive cells including neurons. Tat disrupts neuronal homeostasis and may contribute to the neuropathogenesis in people living with HIV (PLWH). The use of cocaine by PLWH exacerbates neuronal dysfunction. Here, we examined the mechanisms by ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-34539-9

    authors： Mohseni Ahooyi T,Shekarabi M,Torkzaban B,Langford TD,Burdo TH,Gordon J,Datta PK,Amini S,Khalili K

    更新日期：2018-11-02 00:00:00

  • Internal epitope tagging informed by relative lack of sequence conservation.

    abstract：:Many experimental techniques rely on specific recognition and stringent binding of proteins by antibodies. This can readily be achieved by introducing an epitope tag. We employed an approach that uses a relative lack of evolutionary conservation to inform epitope tag site selection, followed by integration of the tag-...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep36986

    authors： Burg L,Zhang K,Bonawitz T,Grajevskaja V,Bellipanni G,Waring R,Balciunas D

    更新日期：2016-11-28 00:00:00

  • Traumatic Brain Injury Leads to Accelerated Atherosclerosis in Apolipoprotein E Deficient Mice.

    abstract：:Traumatic brain injury (TBI) has been associated with atherosclerosis and cardiovascular mortality in humans. However the causal relationship between TBI and vascular disease is unclear. This study investigated the direct role of TBI on vascular disease using a murine model of atherosclerosis. Apolipoprotein E deficie...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-23959-2

    authors： Wang J,Su E,Wang H,Guo C,Lawrence DA,Eitzman DT

    更新日期：2018-04-04 00:00:00

  • Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion.

    abstract：:We have studied differentially regulated nuclear proteome of the clinical tissue specimens of glioblastoma (GBM, WHO Grade IV) and lower grades of gliomas (Grade II and III) using high resolution mass spectrometry- based quantitative proteomics approach. The results showed altered expression of many regulatory protein...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-47360-9

    authors： Gupta MK,Polisetty RV,Sharma R,Ganesh RA,Gowda H,Purohit AK,Ankathi P,Prasad K,Mariswamappa K,Lakshmikantha A,Uppin MS,Sundaram C,Gautam P,Sirdeshmukh R

    更新日期：2019-07-29 00:00:00

  • KampoDB, database of predicted targets and functional annotations of natural medicines.

    abstract：:Natural medicines (i.e., herbal medicines, traditional formulas) are useful for treatment of multifactorial and chronic diseases. Here, we present KampoDB ( http://wakanmoview.inm.u-toyama.ac.jp/kampo/ ), a novel platform for the analysis of natural medicines, which provides various useful scientific resources on Japa...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-29516-1

    authors： Sawada R,Iwata M,Umezaki M,Usui Y,Kobayashi T,Kubono T,Hayashi S,Kadowaki M,Yamanishi Y

    更新日期：2018-07-25 00:00:00

  • The Natural Course of Intermittent Exotropia over a 3-year Period and the Factors Predicting the Control Deterioration.

    abstract：:The natural course of intermittent exotropia and the factors affecting its control has been unclear. We aim to report the natural course of our cohort of 117 Chinese children with intermittent exotropia and to identify baseline parameters that may have predictive value in the control deterioration of the disease. The ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep27113

    authors： Kwok JJ,Chong GS,Ko ST,Yam JC

    更新日期：2016-06-03 00:00:00

  • Author Correction: Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer.

    abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title：Scientific reports

    pub_type： 已发布勘误

    doi：10.1038/s41598-020-68128-6

    authors： Kim MS,Jeong J,Seo J,Kim HS,Kim SJ,Jin W

    更新日期：2020-07-06 00:00:00

  • An Investigation of the Behavior of Solvent based Polycaprolactone ink for Material Jetting.

    abstract：:An initial study of processing bioresorbable polycaprolactone (PCL) through material jetting was conducted using a Fujifilm Dimatix DMP-2830 material printer. The aim of this work was to investigate a potential solvent based method of jetting polycaprolactone. Several solvents were used to prepare a PCL solvent based ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep20852

    authors： He Y,Wildman RD,Tuck CJ,Christie SD,Edmondson S

    更新日期：2016-02-12 00:00:00