A novel design to screen chlorogenic acid-producing microbial strains from the environment.


:The present study aimed to develop a plate-screening method, based on the specific color development of complexes formed between chlorogenic acid, a valuable plant-derived compound, and aluminum (III), to detect chlorogenic acid-producing microbial strains. Modified media with 0.75 mM aluminum chloride were developed to identify CGA-producing bacteria (based on beef extract agar medium) or fungi (based on the potato dextrose agar medium). Compared with conventional screening, the modified media let to 3.3 times more CGA producers from plants, at 90.9% selective accuracy. Novel chlorogenic acid-biosynthesizing strains included Brevibacillus borstelensis B14, Bacillus amyloliquefaciens B17, Bacillus badius B19, Sphingomonas yabuuchiae N21, Enterobacter tabaci N22, and Lodderomyces elongisporus S216 and P212. Strain S216 produced the highest chlorogenic acid yield (23.39 mg L-1). This study provides a highly efficient and low-cost tool for quick detection and subsequent identification of several newly isolated strains with chlorogenic acid-producing potential.


Sci Rep


Scientific reports


Wang X,Qin L,Zhou J,Li Y,Fan X




Has Abstract


2018-10-03 00:00:00












  • Dissimilatory Nitrate Reduction to Ammonium in the Yellow River Estuary: Rates, Abundance, and Community Diversity.

    abstract::Dissimilatory nitrate reduction to ammonium (DNRA) is an important nitrate reduction process in estuarine sediments. This study reports the first investigation of DNRA in the Yellow River Estuary located in Eastern Shandong, China. Saltwater intrusion could affect the physicochemical characteristics and change the mic...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Bu C,Wang Y,Ge C,Ahmad HA,Gao B,Ni SQ

    更新日期:2017-07-28 00:00:00

  • Bivariate genomic analysis identifies a hidden locus associated with bacteria hypersensitive response in Arabidopsis thaliana.

    abstract::Multi-phenotype analysis has drawn increasing attention to high-throughput genomic studies, whereas only a few applications have justified the use of multivariate techniques. We applied a recently developed multi-trait analysis method on a small set of bacteria hypersensitive response phenotypes and identified a singl...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Wang B,Li Z,Xu W,Feng X,Wan Q,Zan Y,Sheng S,Shen X

    更新日期:2017-03-24 00:00:00

  • Optimization of the energy for Breast monochromatic absorption X-ray Computed Tomography.

    abstract::The limits of mammography have led to an increasing interest on possible alternatives such as the breast Computed Tomography (bCT). The common goal of all X-ray imaging techniques is to achieve the optimal contrast resolution, measured through the Contrast to Noise Ratio (CNR), while minimizing the radiological risks,...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Delogu P,Di Trapani V,Brombal L,Mettivier G,Taibi A,Oliva P

    更新日期:2019-09-11 00:00:00

  • Multi-component quantitative magnetic resonance imaging by phasor representation.

    abstract::Quantitative magnetic resonance imaging (qMRI) is a versatile, non-destructive and non-invasive tool in life, material, and medical sciences. When multiple components contribute to the signal in a single pixel, however, it is difficult to quantify their individual contributions and characteristic parameters. Here we i...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Vergeldt FJ,Prusova A,Fereidouni F,Amerongen HV,Van As H,Scheenen TWJ,Bader AN

    更新日期:2017-04-13 00:00:00

  • Organic mulches reduce crop attack by sweetpotato weevil (Cylas formicarius).

    abstract::Mulching with organic materials is a management practice with long history for weed suppression, soil water conservation and erosion control. Its potential impact on crop pests is less well explored. Here we report its utility for reducing crop damage by the serious pest, sweetpotato weevil (Cylas formicarius). Labora...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Rehman M,Liu J,Johnson AC,Dada TE,Gurr GM

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  • Adult vultures outperform juveniles in challenging thermal soaring conditions.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Harel R,Horvitz N,Nathan R

    更新日期:2016-06-13 00:00:00

  • Trauma-specific Grey Matter Alterations in PTSD.

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    journal_title:Scientific reports

    pub_type: 杂志文章,meta分析,评审


    authors: Meng L,Jiang J,Jin C,Liu J,Zhao Y,Wang W,Li K,Gong Q

    更新日期:2016-09-21 00:00:00

  • Single Crystal Organic Nanoflowers.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Sasidharan S,P C S,Chaudhary N,Ramakrishnan V

    更新日期:2017-12-11 00:00:00

  • Alcohol consumption before pregnancy causes detrimental fetal development and maternal metabolic disorders.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Lee YJ,Kim JY,Lee DY,Park KJ,Kim GH,Kim JE,Roh GS,Lim JY,Koo S,Lim NK,Park HY,Kim WH

    更新日期:2020-06-22 00:00:00

  • Development of novel detection system for sweet potato leaf curl virus using recombinant scFv.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Cho SH,Kil EJ,Cho S,Byun HS,Kang EH,Choi HS,Lee MG,Lee JS,Lee YG,Lee S

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  • Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Chamessian A,Young M,Qadri Y,Berta T,Ji RR,Van de Ven T

    更新日期:2018-05-01 00:00:00

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Baker DH,Meese TS

    更新日期:2016-07-27 00:00:00

  • Author Correction: Quantifying Nearshore Sea Turtle Densities: Applications of Unmanned Aerial Systems for Population Assessments.

    abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误


    authors: Sykora-Bodie ST,Bezy V,Johnston DW,Newton E,Lohmann KJ

    更新日期:2018-04-19 00:00:00

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Ahern KW,Serbulea V,Wingrove CL,Palas ZT,Leitinger N,Harris TE

    更新日期:2019-08-01 00:00:00

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Wei C,Wu G,Yang S,Liu Q

    更新日期:2016-10-13 00:00:00

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Zhang D,Lazim R

    更新日期:2017-03-16 00:00:00

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Du H,Chen W,Cai P,Rong X,Dai K,Peacock CL,Huang Q

    更新日期:2016-01-21 00:00:00

  • In-situ Liquid Phase Epitaxy: Another Strategy to Synthesize Heterostructured Core-shell Composites.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Wen Z,Wang G

    更新日期:2016-04-28 00:00:00

  • Efficient engineering of chromosomal ribosome binding site libraries in mismatch repair proficient Escherichia coli.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Oesterle S,Gerngross D,Schmitt S,Roberts TM,Panke S

    更新日期:2017-09-26 00:00:00

  • Deficient Vitamin E Uptake During Development Impairs Neural Tube Closure in Mice Lacking Lipoprotein Receptor SR-BI.

    abstract::SR-BI is the main receptor for high density lipoproteins (HDL) and mediates the bidirectional transport of lipids, such as cholesterol and vitamin E, between these particles and cells. During early development, SR-BI is expressed in extraembryonic tissue, specifically in trophoblast giant cells in the parietal yolk sa...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Santander N,Lizama C,Parga MJ,Quiroz A,Pérez D,Echeverría G,Ulloa L,Palma V,Rigotti A,Busso D

    更新日期:2017-07-12 00:00:00

  • A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Smith AM,Smith AP

    更新日期:2016-12-15 00:00:00

  • Early Postnatal Cardiomyocyte Proliferation Requires High Oxidative Energy Metabolism.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: de Carvalho AETS,Bassaneze V,Forni MF,Keusseyan AA,Kowaltowski AJ,Krieger JE

    更新日期:2017-11-13 00:00:00

  • Gender-based differences in host behavior and gut microbiota composition in response to high fat diet and stress in a mouse model.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Bridgewater LC,Zhang C,Wu Y,Hu W,Zhang Q,Wang J,Li S,Zhao L

    更新日期:2017-09-07 00:00:00

  • The substrate matters in the Raman spectroscopy analysis of cells.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Mikoliunaite L,Rodriguez RD,Sheremet E,Kolchuzhin V,Mehner J,Ramanavicius A,Zahn DR

    更新日期:2015-08-27 00:00:00

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    journal_title:Scientific reports

    pub_type: 杂志文章,meta分析


    authors: Keuken MC,van Maanen L,Boswijk M,Forstmann BU,Steyvers M

    更新日期:2018-10-26 00:00:00

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Li P,Hua P,Gui D,Niu J,Pei P,Zhang J,Krebs P

    更新日期:2020-08-10 00:00:00

  • Analysis of Co-Associated Transcription Factors via Ordered Adjacency Differences on Motif Distribution.

    abstract::Transcription factors (TFs) binding to specific DNA sequences or motifs, are elementary to the regulation of transcription. The gene is regulated by a combination of TFs in close proximity. Analysis of co-TFs is an important problem in understanding the mechanism of transcriptional regulation. Recently, ChIP-seq in ma...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Pan G,Tang J,Guo F

    更新日期:2017-02-27 00:00:00

  • Expression of Estrogen Receptor Beta Predicts Oncologic Outcome of pT3 Upper Urinary Tract Urothelial Carcinoma Better Than Aggressive Pathological Features.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Luo HL,Sung MT,Tsai EM,Lin CS,Lee NL,Chung YH,Chiang PH

    更新日期:2016-04-07 00:00:00

  • Iron acquisition in Pseudomonas aeruginosa by the siderophore pyoverdine: an intricate interacting network including periplasmic and membrane proteins.

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    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Bonneau A,Roche B,Schalk IJ

    更新日期:2020-01-10 00:00:00

  • Differential expression of immune receptors in two marine sponges upon exposure to microbial-associated molecular patterns.

    abstract::The innate immune system helps animals to navigate the microbial world. The response to microbes relies on the specific recognition of microbial-associated molecular patterns (MAMPs) by immune receptors. Sponges (phylum Porifera), as early-diverging animals, provide insights into conserved mechanisms for animal-microb...

    journal_title:Scientific reports

    pub_type: 杂志文章


    authors: Pita L,Hoeppner MP,Ribes M,Hentschel U

    更新日期:2018-10-31 00:00:00