Publisher Correction: Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2.

abstract：:Antimicrobial peptides (AMPs) are an important part of the human innate immune system for protection against bacterial infections, however the AMPs display varying degrees of activity against Staphylococcus aureus. Previously, we showed that inactivation of the ATP synthase sensitizes S. aureus towards the AMP antibio...

journal_title：Scientific reports

authors： Liu L,Beck C,Nøhr-Meldgaard K,Peschel A,Kretschmer D,Ingmer H,Vestergaard M

更新日期：2020-07-09 00:00:00

abstract：:Photoreceptor function is impaired in many retinal diseases like age-related macular degeneration. Currently, assessment of the photoreceptor function for the early diagnosis and monitoring of these diseases is either subjective, as in visual field testing, requires contact with the eye, like in electroretinography, o...

journal_title：Scientific reports

authors： Messner A,Werkmeister RM,Seidel G,Stegmann H,Schmetterer L,Aranha Dos Santos V

更新日期：2019-09-20 00:00:00

abstract：:A multi-angle light scattering (MALS) system, combined with chromatographic separation, directly measures the absolute molar mass, size and concentration of the eluate species. The measurement of these crucial properties in solution is essential in basic macromolecular characterization and all research and production ...

journal_title：Scientific reports

authors： Hsieh VH,Wyatt PJ

更新日期：2017-08-30 00:00:00

abstract：:Quercetin is a natural flavonoid, which has been shown to have anti hepatitis C virus (HCV) properties. However, the exact mechanisms whereby quercetin impacts the HCV life cycle are not fully understood. We assessed the effect of quercetin on different steps of the HCV life cycle in Huh-7.5 cells and primary human he...

journal_title：Scientific reports

authors： Rojas Á,Del Campo JA,Clement S,Lemasson M,García-Valdecasas M,Gil-Gómez A,Ranchal I,Bartosch B,Bautista JD,Rosenberg AR,Negro F,Romero-Gómez M

更新日期：2016-08-22 00:00:00

abstract：:Gallic acid is a trihydroxybenzoic acid found in tea leaves and some plants. Here, we report the effect of gallic acid on cardiac dysfunction and fibrosis in a mouse model of pressure overload-induced heart failure and in primary rat cardiac fibroblasts, and compare the effects of gallic acid with those of drugs used ...

journal_title：Scientific reports

authors： Jin L,Sun S,Ryu Y,Piao ZH,Liu B,Choi SY,Kim GR,Kim HS,Kee HJ,Jeong MH

更新日期：2018-06-18 00:00:00

abstract：:Copper-based compounds are promising entities for target-specific next-generation anticancer and NSAIDS therapeutics. In lieu of this, benzimidazole scaffold plays an important role, because of their wide variety of potential functionalizations and coordination modes. Herein, we report three copper complexes 1-3 with ...

journal_title：Scientific reports

authors： Hussain A,AlAjmi MF,Rehman MT,Amir S,Husain FM,Alsalme A,Siddiqui MA,AlKhedhairy AA,Khan RA

更新日期：2019-03-27 00:00:00

abstract：:Aneuploidy has been reported to occur at remarkably high levels in normal somatic tissues using Fluorescence In Situ Hybridization (FISH). Recently, these reports were contradicted by single-cell low-coverage whole genome sequencing (scL-WGS) analyses, which showed aneuploidy frequencies at least an order of magnitude...

journal_title：Scientific reports

authors： Andriani GA,Maggi E,Piqué D,Zimmerman SE,Lee M,Quispe-Tintaya W,Maslov A,Campisi J,Vijg J,Mar JC,Montagna C

更新日期：2019-07-19 00:00:00

abstract：:Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy. A proteomic study in muscles with reduced PABPN1 levels suggested dysregula...

journal_title：Scientific reports

authors： Olie CS,van der Wal E,Domagoj C,Maton L,de Greef JC,Lin IH,Chen YF,Kareem E,Penninger JM,Kessler BM,Raz V

更新日期：2020-10-19 00:00:00

abstract：:Multi-wavelength lasers have widespread applications (e.g. fiber telecommunications, pump-probe measurements, terahertz generation). Here, we report a nanotube-mode-locked all-fiber ultrafast oscillator emitting three wavelengths at the central wavelengths of about 1540, 1550, and 1560 nm, which are tunable by stretch...

journal_title：Scientific reports

authors： Liu X,Han D,Sun Z,Zeng C,Lu H,Mao D,Cui Y,Wang F

更新日期：2013-01-01 00:00:00

abstract：:In this paper, large area and deep sub-wavelength interference patterns are realized experimentally by using odd surface plasmon modes in the metal/insulator/metal structure. Theoretical investigation shows that the odd modes possesses much higher transversal wave vector and great inhibition of tangential electric fie...

journal_title：Scientific reports

authors： Liu L,Luo Y,Zhao Z,Zhang W,Gao G,Zeng B,Wang C,Luo X

更新日期：2016-07-28 00:00:00

abstract：:The increasing use of new and emerging tobacco products has raised public health concern worldwide. This study aimed to assess the association between tobacco product use and the risk of allergic diseases. We used cross-sectional data of 58,336 students aged 12-18 years from the 2018 Korea Youth Risk Behavior Survey. ...

journal_title：Scientific reports

authors： Lee A,Lee SY,Lee KS

更新日期：2019-11-27 00:00:00

abstract：:This paper reports on a tunable transmission frequency characteristics-based metamaterial absorber of an X band sensing application with a fractional bandwidth. Tunable resonator metamaterial absorbers fabricated with dielectric surface have been the subject of growing attention of late. Absorbers possess electromagne...

journal_title：Scientific reports

authors： Hoque A,Islam MT,Almutairi AF,Chowdhury MEH,Samsuzzaman M

更新日期：2020-08-04 00:00:00

abstract：:Networks science plays an enormous role in many aspects of modern society from distributing electrical power across nations to spreading information and social networking amongst global populations. While modern networks constantly change in size, few studies have sought methods for the difficult task of optimising th...

journal_title：Scientific reports

authors： Wang J,Yu X,Stone L

更新日期：2016-05-11 00:00:00

abstract：:Dysfunction of cortical GABAergic interneurons are involved in numerous neurological disorders including epilepsy, schizophrenia and autism; and replenishment of these cells by transplantation strategy has proven to be a feasible and effective method to help revert the symptoms in several animal models. To develop met...

journal_title：Scientific reports

authors： Wang Q,Hong P,Gao H,Chen Y,Yang Q,Jiang M,Li H

更新日期：2016-01-11 00:00:00

abstract：:We sought to investigate the prevalence, functional characteristics, and clinical significance of right ventricular (RV) involvement in patients with hypertrophic cardiomyopathy (HCM). A total of 256 patients with HCM who underwent both cardiac magnetic resonance (CMR) imaging and transthoracic echocardiography within...

journal_title：Scientific reports

authors： Seo J,Hong YJ,Kim YJ,Lkhagvasuren P,Cho I,Shim CY,Ha JW,Hong GR

更新日期：2020-12-14 00:00:00

abstract：:We study the rotational dynamics of solid chiral and birefringent microparticles induced by elliptically polarized laser light in optical tweezers. We find that both reflection of left circularly polarized light and residual linear retardance affect the particle dynamics. The degree of ellipticity of laser light neede...

journal_title：Scientific reports

authors： Donato MG,Mazzulla A,Pagliusi P,Magazzù A,Hernandez RJ,Provenzano C,Gucciardi PG,Maragò OM,Cipparrone G

更新日期：2016-09-07 00:00:00

abstract：:Peatland ecosystem services include drinking water provision, flood mitigation, habitat provision and carbon sequestration. Dissolved organic carbon (DOC) removal is a key treatment process for the supply of potable water downstream from peat-dominated catchments. A transition from peat-forming Sphagnum moss to vascul...

journal_title：Scientific reports

authors： Ritson JP,Bell M,Brazier RE,Grand-Clement E,Graham NJ,Freeman C,Smith D,Templeton MR,Clark JM

更新日期：2016-11-18 00:00:00

abstract：:The gut of Drosophila melanogaster includes a proximal acidic region (~pH 2), however the genome lacks the H(+)/K(+) ATPase characteristic of the mammalian gastric parietal cell, and the molecular mechanisms of acid generation are poorly understood. Here, we show that maintenance of the low pH of the acidic region is ...

journal_title：Scientific reports

authors： Overend G,Luo Y,Henderson L,Douglas AE,Davies SA,Dow JA

更新日期：2016-06-02 00:00:00

abstract：:Recently, platelet-rich plasma (PRP) has received attention as a treatment for patients with osteoarthritis of the knee (OAK), a chronic degenerative disease, to bridge the gap between conservative and surgical treatments. Here, we investigated the differences in the humoral factors present in two types of PRP purifie...

journal_title：Scientific reports

authors： Wasai S,Sato M,Maehara M,Toyoda E,Uchiyama R,Takahashi T,Okada E,Iwasaki Y,Suzuki S,Watanabe M

更新日期：2020-06-29 00:00:00

abstract：:We investigate the impact of borders on the topology of spatially embedded networks. Indeed territorial subdivisions and geographical borders significantly hamper the geographical span of networks thus playing a key role in the formation of network communities. This is especially important in scientific and technologi...

journal_title：Scientific reports

authors： Cerina F,Chessa A,Pammolli F,Riccaboni M

更新日期：2014-04-01 00:00:00

abstract：:Determining mechanisms that naturally protect species from developing cancer is critical in order to prevent and treat cancer. Here, we describe a novel cancer-suppressing mechanism, via the secretion of bioactive factors by mammary cells, that is present in domesticated mammals with a low mammary cancer incidence. Sp...

journal_title：Scientific reports

authors： Ledet MM,Harman RM,Fan JC,Schmitt-Matzen E,Diaz-Rubio ME,Zhang S,Van de Walle GR

更新日期：2020-11-25 00:00:00

abstract：:Printing techniques are becoming increasingly prevalent in modern manufacturing. However, its biggest drawback is the limit in printing resolution. In this paper, we present solvodynamic printing as a novel printing system which aims to improve print resolution by incorporating an additional immiscible carrier solvent...

journal_title：Scientific reports

authors： Liu WC,Watt AAR

更新日期：2019-07-24 00:00:00

abstract：:The origin of the enantio- and regioselectivity of ring-opening reaction of oxabicyclic alkenes catalyzed by rhodium/Josiphos has been examined using M06-2X density functional theory(DFT). DFT calculations predict a 98% ee for the enantioselectivity and only the 1,2-trans product as one regio- and diastereomer, in exc...

journal_title：Scientific reports

authors： Qi ZH,Zhang Y,Gao Y,Zhang Y,Wang XW,Wang Y

更新日期：2017-01-11 00:00:00

abstract：:Rice lines with slower starch digestibility provide opportunities in mitigating the global rise in type II diabetes and related non-communicable diseases. However, screening for low glycemic index (GI) in rice breeding programs is not possible due to time and cost constraints. This study evaluated the feasibility of u...

journal_title：Scientific reports

authors： Guzman MK,Parween S,Butardo VM,Alhambra CM,Anacleto R,Seiler C,Bird AR,Chow CP,Sreenivasulu N

更新日期：2017-07-19 00:00:00

abstract：:The biological function of sterol glucosides (SGs), the most abundant sterol derivatives in higher plants, remains uncertain. In an effort to improve our understanding of these membrane lipids we examined phenotypes exhibited by the roots of Arabidopsis (Arabidopsis thaliana) lines carrying insertions in the UDP-Glc:s...

journal_title：Scientific reports

authors： Pook VG,Nair M,Ryu K,Arpin JC,Schiefelbein J,Schrick K,DeBolt S

更新日期：2017-07-18 00:00:00

abstract：:The combination of biomaterials and stem cells for clinical applications constitute a great challenge in bone tissue engineering. Hence, cellular networks derived from cells-biomaterials crosstalk have a profound influence on cell behaviour and communication, preceding proliferation and differentiation. The purpose of...

journal_title：Scientific reports

authors： Benjumeda Wijnhoven I,Vallejos R,Santibanez JF,Millán C,Vivanco JF

更新日期：2020-10-05 00:00:00

abstract：:In this paper, 4-(dicyanomethylene)-2-t-butyl-6(1,1,7,7-tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB) has been used in interface modification of dye-sensitized solar cells (DSCs) with combined effects of retarding charge recombination and Förster resonant energy transfer (FRET). DCJTB interface modification significan...

journal_title：Scientific reports

authors： Gao R,Cui Y,Liu X,Wang L

更新日期：2014-07-04 00:00:00

abstract：:Gamma-aminobutyric acid (GABA) is a widely conserved signaling molecule that in animals has been adapted as a neurotransmitter. GABA is synthesized from the amino acid glutamate by the action of glutamate decarboxylases (GADs). Two vertebrate genes, GAD1 and GAD2, encode distinct GAD proteins: GAD67 and GAD65, respect...

journal_title：Scientific reports

authors： Grone BP,Maruska KP

更新日期：2016-07-27 00:00:00

abstract：:The South Asian subcontinent is characterized by a complex history of human migrations and population interactions. In this study, we used genome-wide data to provide novel insights on the demographic history and population relationships of six Indo-European populations from the Indian State of West Maharashtra. The s...

journal_title：Scientific reports

authors： Debortoli G,Abbatangelo C,Ceballos F,Fortes-Lima C,Norton HL,Ozarkar S,Parra EJ,Jonnalagadda M

更新日期：2020-06-22 00:00:00

abstract：:Pseudomonas aeruginosa is a major threat for immune-compromised patients. Bacterial pneumonia can induce uncontrolled and massive neutrophil recruitment ultimately leading to acute respiratory distress syndrome and epithelium damage. Interleukin-22 plays a central role in the protection of the epithelium. In this stud...

journal_title：Scientific reports

authors： Broquet A,Jacqueline C,Davieau M,Besbes A,Roquilly A,Martin J,Caillon J,Dumoutier L,Renauld JC,Heslan M,Josien R,Asehnoune K

更新日期：2017-09-08 00:00:00